Methyl palmitate

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    112-39-0

    Molecular formula
    C17H34O2

    SMILES
    CCCCCCCCCCCCCCCC(=O)OC

    Safety labels

    Irritant
    Irritant

    Retention indicies (RI)

    • DB5: 1924.67
    • Carbowax: 2193.71

  • Odor profile

    Waxy 78.44%
    Fatty 74.55%
    Oily 63.62%
    Sweet 39.95%
    Creamy 37.34%
    Dairy 30.18%
    Fruity 29.59%
    Soapy 26.29%
    Odorless 25.58%
    Coconut 24.61%

    Scent© AI

  • Properties

    XLogP3-AA
    7.9

    pKa est.
    7.53 (neutral)

    Molecular weight
    270.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 30 °C

    Boiling point

    • 417 °C

    Flash point est.
    142.09 ˚C

    Solubility expt.

    • Insol in water; very sol in ethyl alc, acetone; sol in ether
    • Insoluble in water, soluble in alcohol and ether

  • Synonyms

    • METHYL PALMITATE
    • Methyl hexadecanoate
    • 112-39-0
    • Palmitic acid methyl ester
    • Hexadecanoic acid, methyl ester
    • Palmitic acid, methyl ester
    • Methyl n-hexadecanoate
    • Uniphat A60
    • Metholene 2216
    • n-Hexadecanoic acid methyl ester
    • Hexadecanoic acid methyl ester
    • HSDB 5570
    • UNII-DPY8VCM98I
    • DPY8VCM98I
    • NSC 4197
    • EINECS 203-966-3
    • MFCD00008994
    • AI3-03509
    • DUB PM COS
    • NSC-4197
    • AEC METHYL PALMITATE
    • DTXSID4029149
    • CHEBI:69187
    • EC 203-966-3
    • WE(1:0/16:0)
    • METHYL PALMITATE (USP-RS)
    • METHYL PALMITATE [USP-RS]
    • Methyl hexadecanoate; Hexadecanoic acid methyl ester
    • methylpalmitate
    • hexadecanoic acid-methyl ester
    • formyl hexadecanoate
    • Methyl palmitic acid
    • palmitic methyl ester
    • methyl hexadecanoic acid
    • a methylhexadecanoic acid
    • Emery 2216
    • Radia 7120
    • Hexadecanoate methyl ester
    • C16 FAME
    • Methyl palmitate (Standard)
    • Methyl palmitate, >=97%
    • SCHEMBL37365
    • CHEMBL335125
    • DTXCID909149
    • METHYL PALMITATE [HSDB]
    • HY-N1482R
    • MSK1814
    • NSC4197
    • HMS3650G09
    • CS-D1457
    • HY-N1482
    • Tox21_202768
    • BBL010507
    • LMFA07010470
    • Methyl palmitate, analytical standard
    • s9383
    • STL146153
    • AKOS005715213
    • CCG-267168
    • NCGC00260315-01
    • CAS-112-39-0
    • Methyl palmitate, >=99% (capillary GC)
    • DB-041084
    • Hexadecanoic acid methyl ester (FAME MIX)
    • NS00006070
    • P0006
    • S0311
    • C16995
    • D70331
    • EN300-18532402
    • SR-01000946783
    • SR-01000946783-1
    • Q16676086
    • 844D5088-5CCF-4B2D-A678-EA5A7E8CB149
    • Methyl palmitate, United States Pharmacopeia (USP) Reference Standard
    • 203-966-3

  • Applications

    Methyl palmitate (CAS 112-39-0) is the methyl ester of palmitic acid naturally present in palm oil, coconut oil and animal fats; its chemical inertness, moderate viscosity and mild odor make it widely employed as a biodiesel component, biodegradable lubricant base stock, nontoxic solvent, soft plasticizer for food-contact polymers, antifoaming agent in sugar refining, emulsifier and skin-conditioning agent in cosmetics, flavor carrier in foods, intermediate for surfactant synthesis, internal standard for GC-MS fatty-acid analysis, as well as a pharmaceutical excipient for microencapsulation and transdermal permeation enhancement.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 166.91
    methanol 149.01
    isopropanol 292.83
    water 0.01
    ethyl acetate 1232.32
    n-propanol 261.43
    acetone 695.66
    n-butanol 315.84
    acetonitrile 311.56
    DMF 935.87
    toluene 417.14
    isobutanol 288.76
    1,4-dioxane 1023.47
    methyl acetate 645.83
    THF 2095.1
    2-butanone 963.09
    n-pentanol 233.43
    sec-butanol 350.01
    n-hexane 157.21
    ethylene glycol 8.66
    NMP 1486.93
    cyclohexane 636.64
    DMSO 941.3
    n-butyl acetate 1222.9
    n-octanol 222.45
    chloroform 2377.98
    n-propyl acetate 1321.68
    acetic acid 233.65
    dichloromethane 2441.59
    cyclohexanone 2531.75
    propylene glycol 36.29
    isopropyl acetate 1082.21
    DMAc 1185.54
    2-ethoxyethanol 441.1
    isopentanol 417.58
    n-heptane 141.23
    ethyl formate 453.68
    1,2-dichloroethane 1818.55
    n-hexanol 242.83
    2-methoxyethanol 484.39
    isobutyl acetate 780.71
    tetrachloromethane 579.58
    n-pentyl acetate 1231.22
    transcutol 2085.02
    n-heptanol 201.29
    ethylbenzene 313.33
    MIBK 921.79
    2-propoxyethanol 473.51
    tert-butanol 556.04
    MTBE 997.61
    2-butoxyethanol 490.92
    propionic acid 295.23
    o-xylene 354.64
    formic acid 29.54
    diethyl ether 874.56
    m-xylene 326.51
    p-xylene 457.58
    chlorobenzene 715.79
    dimethyl carbonate 171.24
    n-octane 54.02
    formamide 80.46
    cyclopentanone 2132.8
    2-pentanone 1115.06
    anisole 598.83
    cyclopentyl methyl ether 1389.51
    gamma-butyrolactone 1805.86
    1-methoxy-2-propanol 569.36
    pyridine 1204.0
    3-pentanone 855.73
    furfural 1238.23
    n-dodecane 27.16
    diethylene glycol 147.84
    diisopropyl ether 407.56
    tert-amyl alcohol 564.08
    acetylacetone 1193.99
    n-hexadecane 34.91
    acetophenone 687.16
    methyl propionate 715.31
    isopentyl acetate 1102.99
    trichloroethylene 2799.01
    n-nonanol 224.62
    cyclohexanol 744.82
    benzyl alcohol 326.24
    2-ethylhexanol 311.88
    isooctanol 239.88
    dipropyl ether 867.82
    1,2-dichlorobenzene 851.76
    ethyl lactate 308.65
    propylene carbonate 1018.44
    n-methylformamide 291.52
    2-pentanol 320.67
    n-pentane 91.82
    1-propoxy-2-propanol 600.66
    1-methoxy-2-propyl acetate 896.05
    2-(2-methoxypropoxy) propanol 430.71
    mesitylene 266.29
    ε-caprolactone 1951.06
    p-cymene 240.85
    epichlorohydrin 1972.73
    1,1,1-trichloroethane 2054.12
    2-aminoethanol 50.39
    morpholine-4-carbaldehyde 1231.45
    sulfolane 2432.56
    2,2,4-trimethylpentane 74.9
    2-methyltetrahydrofuran 1838.89
    n-hexyl acetate 1112.99
    isooctane 52.08
    2-(2-butoxyethoxy)ethanol 622.61
    sec-butyl acetate 1000.21
    tert-butyl acetate 1317.16
    decalin 180.11
    glycerin 59.43
    diglyme 1484.38
    acrylic acid 167.1
    isopropyl myristate 352.88
    n-butyric acid 830.23
    acetyl acetate 629.96
    di(2-ethylhexyl) phthalate 222.94
    ethyl propionate 1096.37
    nitromethane 675.36
    1,2-diethoxyethane 1175.96
    benzonitrile 574.45
    trioctyl phosphate 179.32
    1-bromopropane 1163.85
    gamma-valerolactone 2436.9
    n-decanol 140.38
    triethyl phosphate 423.12
    4-methyl-2-pentanol 243.28
    propionitrile 447.39
    vinylene carbonate 723.35
    1,1,2-trichlorotrifluoroethane 1114.76
    DMS 517.66
    cumene 215.83
    2-octanol 214.81
    2-hexanone 1017.31
    octyl acetate 402.81
    limonene 492.72
    1,2-dimethoxyethane 1452.34
    ethyl orthosilicate 425.05
    tributyl phosphate 264.67
    diacetone alcohol 873.07
    N,N-dimethylaniline 407.71
    acrylonitrile 422.64
    aniline 390.01
    1,3-propanediol 138.04
    bromobenzene 911.81
    dibromomethane 1652.32
    1,1,2,2-tetrachloroethane 2815.41
    2-methyl-cyclohexyl acetate 751.24
    tetrabutyl urea 384.5
    diisobutyl methanol 258.35
    2-phenylethanol 303.41
    styrene 390.63
    dioctyl adipate 528.25
    dimethyl sulfate 391.37
    ethyl butyrate 1182.66
    methyl lactate 203.23
    butyl lactate 575.93
    diethyl carbonate 557.07
    propanediol butyl ether 344.31
    triethyl orthoformate 779.52
    p-tert-butyltoluene 223.41
    methyl 4-tert-butylbenzoate 625.96
    morpholine 1514.3
    tert-butylamine 406.96
    n-dodecanol 100.69
    dimethoxymethane 592.45
    ethylene carbonate 753.23
    cyrene 438.9
    2-ethoxyethyl acetate 1080.24
    2-ethylhexyl acetate 939.36
    1,2,4-trichlorobenzene 964.5
    4-methylpyridine 1147.09
    dibutyl ether 858.73
    2,6-dimethyl-4-heptanol 258.35
    DEF 1379.06
    dimethyl isosorbide 1033.36
    tetrachloroethylene 1726.04
    eugenol 450.1
    triacetin 891.43
    span 80 454.58
    1,4-butanediol 56.2
    1,1-dichloroethane 1629.34
    2-methyl-1-pentanol 306.4
    methyl formate 191.23
    2-methyl-1-butanol 359.42
    n-decane 67.97
    butyronitrile 609.19
    3,7-dimethyl-1-octanol 275.54
    1-chlorooctane 345.83
    1-chlorotetradecane 100.67
    n-nonane 70.61
    undecane 39.08
    tert-butylcyclohexane 133.83
    cyclooctane 135.58
    cyclopentanol 647.35
    tetrahydropyran 1912.03
    tert-amyl methyl ether 819.76
    2,5,8-trioxanonane 810.73
    1-hexene 391.84
    2-isopropoxyethanol 433.68
    2,2,2-trifluoroethanol 100.4
    methyl butyrate 1541.8

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Ambrette seed 1 8015-62-1 Hibiscus abelmoschus L. (Abelmoschus moschatus Moench), fam. Malvaceae 0.44%
Genet absolute 1 8023-80-1 Spartium junceum L., fam. Leguminosae (Papilionaceae) 0.55%
Jasmine (Indonesia) 8022-96-6 Jasminum officinale var. grandiflorum L. (Red Flower), fam. Oleaceae 0.95%
Jasmine sambac (Indonesia) Jasminum sambac (L.) Aiton, fam. Oleaceae 2.28%
Lily headspace Lilium candidum L., fam. Liliaceae 3.5%
Michelia champaca flower absolute Michelia champaca L., fam. Magnoliaceae 3.0%
Myrtle berry (Italy) 8008-46-6 Myrtus communis L., fam. Myrtaceae 4.1%
Parsley absolute (Egypt) 8000-68-8 Petroselinum crispum (Miller) A.W. Hill (P. sativum Hoffm.), fam. Apiaceae 0.11%
Wistaria sinensis headspace Wistaria sinensis DC., fam. Leguminosae (Papilionaceae) 4.0%
Apple flower Malus arnoldiana (Rehd) Sarg. var. Redgold, fam. Rosaceae 0.09%
Melittis melissophyllum Melittis melissophylum L., ssp. albida Guss, fam. Lamiaceae (Labiatae) 0.38%
Jasmine absolute (India) 2 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 5.7%
Jasmine oil (India) 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 2.6%
Hedychium coronarium flower (Japan) Hedychium coronarium Koenig, fam. Zingiberaceae 0.09%
Daphne genkwa Daphne genkwa Sieb. et Zucc., fam. Thymelaeaceae 0.01%
Narcissus poeticus absolute 8023-75-4 Narcissus poeticus L., fam. Amaryllidaceae 0.1%
Jasmine oil (Turkey) 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 0.13%
Jasmine absolute (Turkey) 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 0.35%
Jasmine absolute (France) 2 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 0.41%
Jasmine absolute (Italy) 2 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 1.0%
Jasmine absolute (India) 1 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 1.5%
Jasmine absolute (Morocco) 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 0.75%
Jasmine absolute (Egypt) 2 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 1.0%
Osmanthus concentrate 1 (Sukhumi-Abkhasia) 68917-05-5 Osmanthus fragrans (Thunb.) Lour., fam. Oleaceae 0.08%
Osmanthus concentrate 2 (Sukhumi-Abkhasia) 68917-05-5 Osmanthus fragrans (Thunb.) Lour., fam. Oleaceae 0.07%
Jasmine absolute (Japan) 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 1.33%
Diospyros discolor, fruit peel Diospyros discolor Willd., Ebenaceae (D. blancoi), fam. Ebenaceae 2.0%
Mustard seed (China) 1 8007-40-7 Brassica juncea (L.) Czern. et Coss., fam. Brassicaceae (Crucifereae) 3.53%
Coriander fruit (Finland) 4 8008-52-4 Coriandrum sativum L., fam. Apiaceae (Umbelliferae) 0.1%
Grape flower 84929-27-1 Vitis vinifera L., ssp. Gruener Veltliner, fam. Vitaceae 0.01%
Genet absolute 2 8023-80-1 Spartium junceum L., fam. Leguminosae (Papilionaceae) 0.4%
Dendranthema vestitum flower absolute (China) Dendranthema vestitum (Hemsl.) Ling ex Shih, fam. Asteraceae (Compositae) 1.35%
Jasmine (China) 1 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 5.51%
Jasmine absolute (Egypt) 4 8022-96-6 Jasminum officinale var. grandiflorum L., fam. Oleaceae 1.56%
Jasmine azoricum concrete Jasminum azoricum L., fam. Oleaceae 6.2%
Jasmine sambac (France) concrete Jasminum sambac (L.) Aiton, fam. Oleaceae 2.1%
Rhubarb root Rheum palmatum L., fam. Polygonaceae 0.3%
Honeysuckle, japanese Lonicera japonica L., fam. Caprifoliaceae 1.4%
Boronia megastigma 91771-36-7 Boronia megastigma Nees., fam. Rutaceae 0.02%
Acacia confusa flower (China) Acacia confusa Merr., fam. Mimosaceae (Leguminosae) 9.39%
Cinnamon fruit (India) 1 8007-80-5 Cinnamomum zeylanicum Blume (C. verum L. Presl), fam. Lauraceae 0.15%
Sage, dalmatian (Cuba) 8022-56-8 Salvia officinalis L., fam. Lamiaceae (Labiatae) 0.26%
Pelargonium reniforme Pelargonium reniforme Curt., fam. Geraniaceae 0.6%
Yarrow (Cuba) 84082-83-7 Achillea millefolium L., fam. Asteraceae (Compositae) 0.8%
Kewda (India) Pandanus fascicularis Lam., var. fascilarris, fam. Pandanaceae 0.05%
Genipap fruit (Brazil) Genipa americana L., fam. Rubiaceae 0.1%
Rollinia mucosa fruit Rollinia mucosa (Jacq.) Baill, fam. Annonaceae 0.1%
Chicory root, roasted 1a 68650-43-1 Cichorium intybus L., fam. Asteraceae (Compositae) 0.02%
Pineapple pulp Ananas comosus (L.) Merr., fam. Bromeliaceae 0.07%
Carapa guianensis Carapa guianensis Aubl., fam. Meliaceae 0.1%