• Identifiers

    CAS number
    481-34-5

    Molecular formula
    C15H26O

    SMILES
    CC1=C[C@H]2[C@@H](CC[C@@]([C@@H]2CC1)(C)O)C(C)C

    Retention indicies (RI)

    • DB5: 1655.0
    • Carbowax: 2200.71
  • Odor profile

    Herbal 75.68%
    Woody 67.43%
    Spicy 62.37%
    Earthy 48.65%
    Floral 47.26%
    Mint 45.86%
    Fresh 44.79%
    Balsamic 42.72%
    Green 41.0%
    Pine 39.53%

    Scent© AI

  • Properties

    XLogP3-AA
    3.3

    Molecular weight
    222.37 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 74.5 - 75 °C

    Boiling point

    • 302.00 to 304.00 °C. @ 760.00 mm Hg

    Flash point est.
    115.03 ˚C

  • Synonyms

    • alpha-Cadinol
    • Cadin-4-en-10-ol
    • 481-34-5
    • l-alpha-Cadinol
    • (-)-alpha-Cadinol
    • DC0YJ4816P
    • alpha-Cadinol, (-)-
    • UNII-DC0YJ4816P
    • (1R,4S,4aR,8aR)-1,6-dimethyl-4-propan-2-yl-3,4,4a,7,8,8a-hexahydro-2H-naphthalen-1-ol
    • l-.alpha.-Cadinol
    • (-)-.alpha.-Cadinol
    • .alpha.-Cadinol
    • a-Cadinol
    • (1R,4S,4aR,8aR)-4-Isopropyl-1,6-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-ol
    • 1-Naphthalenol, 1,2,3,4,4a,7,8,8a-octahydro-1,6-dimethyl-4-(1-methylethyl)-, (1R,4S,4aR,8aR)-
    • CADINOL, ALPHA-
    • CHEMBL486795
    • SCHEMBL4276031
    • CHEBI:132905
    • DTXSID701017679
    • .ALPHA.-CADINOL, (-)-
    • HY-N12805
    • CS-1050967
    • NS00093939
    • G89229
    • Q4734900
    • (1R-(1.ALPHA.,4.BETA.,4A.BETA.,8A.ALPHA.))-
    • 1-NAPHTHALENOL, 1,2,3,4,4A,7,8,8A-OCTAHYDRO-1,6-DIMETHYL-4-(1-METHYLETHYL)-,
    • (1R,4S,4AR,8AR)-1,2,3,4,4A,7,8,8A-OCTAHYDRO-1,6-DIMETHYL-4-(1-METHYLETHYL)-1-NAPHTHALENOL
    • (1R,4S,4aR,8aR)-1,6-dimethyl-4-(propan-2-yl)-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-ol
  • Applications

    Cadin-4-en-10-ol (CAS 481-34-5) is a sesquiterpenoid alcohol with a warm, woody, balsamic odor, used primarily in perfumery and consumer products as a fragrance ingredient and fixative to deliver natural woody notes and enhance depth and longevity; it also features in essential-oil blends for aromatherapy, serves in research and quality control as an analytical reference for profiling resin/wood oils and as a botanical marker, and is widely investigated for antimicrobial, antifungal, insect-repellent, and bio-based preservation functions (e.g., protecting wood and natural fibers), indicating potential in biopesticides, anti-mold treatments, and sustainable packaging additives; additionally, Cadin-4-en-10-ol can be used as an intermediate to prepare functional terpene derivatives, noting that non-fragrance applications typically require safety assessment and regulatory clearance prior to commercialization.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 214.6
    methanol 146.5
    isopropanol 230.06
    water 0.25
    ethyl acetate 245.91
    n-propanol 215.02
    acetone 273.65
    n-butanol 237.29
    acetonitrile 179.65
    DMF 219.78
    toluene 353.18
    isobutanol 170.63
    1,4-dioxane 754.45
    methyl acetate 208.47
    THF 1170.93
    2-butanone 291.97
    n-pentanol 122.19
    sec-butanol 164.66
    n-hexane 46.48
    ethylene glycol 13.19
    NMP 195.18
    cyclohexane 135.88
    DMSO 163.64
    n-butyl acetate 349.53
    n-octanol 152.97
    chloroform 700.13
    n-propyl acetate 153.19
    acetic acid 88.42
    dichloromethane 502.0
    cyclohexanone 455.56
    propylene glycol 35.09
    isopropyl acetate 193.25
    DMAc 190.88
    2-ethoxyethanol 121.86
    isopentanol 205.92
    n-heptane 77.96
    ethyl formate 132.27
    1,2-dichloroethane 260.56
    n-hexanol 306.66
    2-methoxyethanol 215.6
    isobutyl acetate 141.56
    tetrachloromethane 114.2
    n-pentyl acetate 199.56
    transcutol 671.49
    n-heptanol 149.01
    ethylbenzene 142.11
    MIBK 180.23
    2-propoxyethanol 320.25
    tert-butanol 261.56
    MTBE 319.77
    2-butoxyethanol 195.23
    propionic acid 89.33
    o-xylene 169.19
    formic acid 16.22
    diethyl ether 330.23
    m-xylene 213.27
    p-xylene 181.77
    chlorobenzene 258.88
    dimethyl carbonate 64.61
    n-octane 28.05
    formamide 32.86
    cyclopentanone 473.23
    2-pentanone 252.81
    anisole 211.96
    cyclopentyl methyl ether 368.86
    gamma-butyrolactone 374.92
    1-methoxy-2-propanol 223.22
    pyridine 444.67
    3-pentanone 172.92
    furfural 272.36
    n-dodecane 22.79
    diethylene glycol 139.96
    diisopropyl ether 121.0
    tert-amyl alcohol 163.84
    acetylacetone 234.84
    n-hexadecane 27.19
    acetophenone 171.42
    methyl propionate 160.2
    isopentyl acetate 320.52
    trichloroethylene 476.07
    n-nonanol 140.63
    cyclohexanol 227.76
    benzyl alcohol 141.75
    2-ethylhexanol 193.82
    isooctanol 122.71
    dipropyl ether 287.61
    1,2-dichlorobenzene 193.58
    ethyl lactate 62.93
    propylene carbonate 207.07
    n-methylformamide 84.96
    2-pentanol 150.8
    n-pentane 58.79
    1-propoxy-2-propanol 280.64
    1-methoxy-2-propyl acetate 280.37
    2-(2-methoxypropoxy) propanol 209.65
    mesitylene 135.24
    ε-caprolactone 330.4
    p-cymene 142.36
    epichlorohydrin 442.16
    1,1,1-trichloroethane 311.91
    2-aminoethanol 45.74
    morpholine-4-carbaldehyde 296.53
    sulfolane 268.56
    2,2,4-trimethylpentane 29.57
    2-methyltetrahydrofuran 646.3
    n-hexyl acetate 282.6
    isooctane 31.26
    2-(2-butoxyethoxy)ethanol 277.23
    sec-butyl acetate 125.82
    tert-butyl acetate 217.8
    decalin 49.27
    glycerin 45.17
    diglyme 451.78
    acrylic acid 59.52
    isopropyl myristate 133.14
    n-butyric acid 204.09
    acetyl acetate 151.67
    di(2-ethylhexyl) phthalate 123.65
    ethyl propionate 127.02
    nitromethane 151.28
    1,2-diethoxyethane 347.24
    benzonitrile 227.06
    trioctyl phosphate 93.44
    1-bromopropane 274.25
    gamma-valerolactone 507.61
    n-decanol 107.36
    triethyl phosphate 92.23
    4-methyl-2-pentanol 110.41
    propionitrile 205.95
    vinylene carbonate 197.13
    1,1,2-trichlorotrifluoroethane 168.04
    DMS 154.38
    cumene 101.09
    2-octanol 106.8
    2-hexanone 167.71
    octyl acetate 157.63
    limonene 186.56
    1,2-dimethoxyethane 323.17
    ethyl orthosilicate 97.25
    tributyl phosphate 100.11
    diacetone alcohol 181.74
    N,N-dimethylaniline 140.58
    acrylonitrile 166.48
    aniline 231.68
    1,3-propanediol 107.25
    bromobenzene 298.28
    dibromomethane 370.67
    1,1,2,2-tetrachloroethane 352.88
    2-methyl-cyclohexyl acetate 198.65
    tetrabutyl urea 128.6
    diisobutyl methanol 123.55
    2-phenylethanol 216.13
    styrene 161.81
    dioctyl adipate 155.83
    dimethyl sulfate 74.05
    ethyl butyrate 208.32
    methyl lactate 64.44
    butyl lactate 139.57
    diethyl carbonate 123.2
    propanediol butyl ether 167.8
    triethyl orthoformate 157.1
    p-tert-butyltoluene 148.26
    methyl 4-tert-butylbenzoate 188.14
    morpholine 670.97
    tert-butylamine 212.48
    n-dodecanol 84.83
    dimethoxymethane 258.57
    ethylene carbonate 176.2
    cyrene 152.0
    2-ethoxyethyl acetate 239.73
    2-ethylhexyl acetate 265.52
    1,2,4-trichlorobenzene 224.36
    4-methylpyridine 429.97
    dibutyl ether 210.67
    2,6-dimethyl-4-heptanol 123.55
    DEF 185.98
    dimethyl isosorbide 356.31
    tetrachloroethylene 214.15
    eugenol 162.38
    triacetin 206.08
    span 80 214.91
    1,4-butanediol 32.63
    1,1-dichloroethane 310.96
    2-methyl-1-pentanol 124.23
    methyl formate 70.09
    2-methyl-1-butanol 167.43
    n-decane 40.85
    butyronitrile 273.2
    3,7-dimethyl-1-octanol 164.05
    1-chlorooctane 115.91
    1-chlorotetradecane 53.2
    n-nonane 38.66
    undecane 29.65
    tert-butylcyclohexane 45.62
    cyclooctane 52.16
    cyclopentanol 216.15
    tetrahydropyran 835.92
    tert-amyl methyl ether 178.33
    2,5,8-trioxanonane 322.33
    1-hexene 135.15
    2-isopropoxyethanol 111.06
    2,2,2-trifluoroethanol 28.35
    methyl butyrate 152.26

    Scent© AI

1 of 4
Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
No restriction
Category 2
Products applied to the axillae
No restriction Category 7B
Leave-on products applied to the hair with some hand contact
No restriction
Category 3
Products applied to the face/body using fingertips
No restriction Category 8
Products with significant anogenital exposure
No restriction
Category 4
Products related to fine fragrance
No restriction Category 9
Products with body and hand exposure, primarily rinse off
No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
No restriction Category 10A
Household care products with mostly hand contact
No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
No restriction
Category 5D
Baby Creams, baby Oils and baby talc
No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
No restriction
Category 6
Products with oral and lip exposure
No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
No restriction
Name CAS Botanical Proportion
Amomum pavieanum rhizome Amomum pavieanum Pierre & Gagnep, fam. Zingiberaceae 0.1%
Ayou Aydendron barbeyana Mez. (Nectandra globosa Mez.), fam. Lauraceae 2.45%
Basil (Egypt) 1 (linalool-type) 8015-73-4 Ocimum basilicum L., fam. Lamiaceae (Labiatae) 0.2%
Basil (Madagascar) 1 8015-73-4 Ocimum basilicum L., fam. Lamiaceae (Labiatae) 0.01%
Basil (Pakistan) 8015-73-4 Ocimum basilicum L., fam. Lamiaceae (Labiatae) 0.01%
Basil (Vietnam) 8015-73-4 Ocimum basilicum L., fam. Lamiaceae (Labiatae) 0.01%
Basil (Yugoslavia) 8015-73-4 Ocimum basilicum L., fam. Lamiaceae (Labiatae) 0.4%
Bergamot (Italy) 3 8007-75-8 Citrus bergamia Risso et Poiteau, fam. Rutaceae 0.01%
Blackcurrant bud 1 68606-81-5 Ribes nigrum L., fam. Grossulariaceae 0.01%
Cedarleaf 3 8000-27-9 Thuja occidentalis L., fam. Taxodiaceae 0.21%
Cedrela odorata Cedrela odorata L., fam. Meliaceae 1.5%
Coleonema pulchellum Coleonema pulchellum Williams (C. pulchrum Hook.), fam. Rutaceae 0.17%
Cypress 8013-86-3 Cupressus sempervirens L. (C. fastigiata DC), fam. Cupressaceae 0.7%
Eugenia javanica Eugenia javanica Lamk., fam. Myrtaceae 0.9%
Fern, sweet 1 Comptonia peregrina (L.) Coulter, fam. Pteridophytae 0.47%
Fern, sweet 2 Comptonia peregrina (L.) Coulter, fam. Pteridophytae 0.25%
Spike lavender (Spain) 3 8016-78-2 Lavandula latifolia Medikus (L. spica D.C.), fam. Lamiaceae (Labiatae) 0.01%
Hinoki root Chamaecyparis obtusa (Sieb. et Zucc.) Endl., fam. Cupressaceae 5.28%
Hinoki wood Chamaecyparis obtusa (Sieb. et Zucc.) Endl., fam. Cupressaceae 20.51%
Hyptis pectinata Hyptis pectinata (L.) Poit., fam. Lamiaceae (Labiatae) 0.1%
Juniper berry 1 8012-91-7 Juniperus communis L., fam. Cupressaceae 0.04%
Juniper berry 5 8012-91-7 Juniperus communis L., fam. Cupressaceae 1.3%
Juniperus foetidissima leaf Juniperus foetidissima Willd., fam. Cupressaceae 1.0%
Dracocephalum kotschyi Dracocephalum kotschyi Boiss., fam. Lamiaceae (Labiatae) 0.3%
Larix conifer bark Larix decidua Mill., fam. Pinaceae 1.07%
Larix conifer needle Larix decidua Mill., fam. Pinaceae 4.16%
Lavender (Spain) (var. pyrenaica) Lavandula angustifolia Mill. ssp. pyrenaica, fam. Lamiaceae (Labiatae) 0.6%
Lavandula luisieri (Chemotype A) Lavandula luisieri L., Chemotype A, fam. Lamiaceae (Labiatae) 2.1%
Lavandula luisieri (Chemotype B) Lavandula luisieri L., Chemotype B, fam. Lamiaceae (Labiatae) 1.9%
Lavandula stoechas (ssp. sampaioana A) Lavandula stoechas L. (ssp. sampaioana, Chemotype A), fam. Lamiaceae 0.5%
Lavandula stoechas (ssp. pedunculata A) Lavandula stoechas L. (ssp. pedunculata, Chemotype A), fam. Lamiaceae 1.2%
Lavandula stoechas (ssp. pedunculata B) Lavandula stoechas L. (ssp. pedunculata, Chemotype B), fam. Lamiaceae 0.2%
Lavandula stoechas (ssp. sampaioana B) Lavandula stoechas L. (ssp. sampaioana, Chemotype B), fam. Lamiaceae 0.05%
Lavandula stoechas (ssp. stoechas) Lavandula stoechas L. (ssp. stoechas), fam. Lamiaceae (Labiatae) 0.1%
Lavandula viridis Lavandula viridis L., fam. Lamiaceae (Labiatae) 2.5%
Lavender (France) 2a 8000-28-0 Lavandula angustifolia Mill. (L. officinalis Chaix), fam. Lamiaceae 0.01%
Lotus flower Nelumbo nucifera L., fam. Nelumbonaceae 0.7%
Lovage root (France) 8016-31-7 Levisticum officinale Koch, fam. Apiaceae (Umbelliferae) 0.28%
Lemon balm 4 ssp. altimissia 8014-71-9 Melissa officinalis L. ssp.altissima (Sibthr. et Smith) Arcang., Lamiaceae 3.1%
Nepeta cataria 2 84929-35-1 Nepeta cataria L. var. citriodora, fam. Lamiaceae (Labiatae) 5.0%
Picea engelmanni needle Picea engelmanni (Parry) Engelm., fam. Pinaceae 0.52%
Picea engelmanni twigs with needles Picea engelmanni (Parry) Engelm., fam. Pinaceae 0.52%
Pinus cembra Pinus cembra L. ssp. cembra (Swiss Stone Pine), fam. Pinaceae 0.41%
Pinus mugo (Dwarf pine) 2 8000-26-8 Pinus mugo Turra ssp. pumilio (P. montana Miller), fam. Pinaceae 0.01%
Pinus nigra Pinus nigra Arnold (Austrian Pine), fam. Pinaceae 0.89%
Pinus sylvestris 5 8023-99-2 Pinus sylvestris L. (Scotch pine), fam. Pinaceae 1.29%
Pinus strobus 2 Pinus strobus L. (North American Eastern White Pine), fam. Pinaceae 0.4%
Rose (Bulgaria) 3a 8007-01-0 Rosa damascena Mill., fam. Rosaceae 0.05%
Santolina pectina Santolina pectina Lag., fam. Asteraceae (Compositae) 9.3%
Santolina semidentata Santolina semidentata Hoffmanns. & Link, fam. Asteraceae (Compositae) 4.9%
Eucalyptus globulus (Spain) 2c mature fruits 8016-26-0 Eucalyptus globulus Labill., fam. Myrtaceae 0.2%
Eucalyptus citriodora (Rwanda) 8008-48-4 Eucalyptus citriodora Hook. f., fam. Myrtaceae 0.55%
Eucalyptus globulus (Italy) 1a hydrodistiled 8016-26-0 Eucalyptus globulus Labill., fam. Myrtaceae 0.6%
Eucalyptus globulus (Italy) 1b CO2-extract 8016-26-0 Eucalyptus globulus Labill., fam. Myrtaceae 0.5%
Hyptis crenata (Brazil) Hyptis crenata Pohl ex Benth, fam. Lamiaceae (Labiatae) 0.2%
Tejpat leaf Cinnamomum tamala (Ham.) Nees et Eberm., fam. Lauraceae 1.5%
Juniperus cedrus (Portugal-Madeira) Juniperus cedrus Webb & Berth. (J. oxycedrus L), fam. Cupressaceae 0.05%
Lantana camara (India) 1a leaf 90046-17-6 Lantana camara L., fam. Verbenaceae 1.8%
Lantana camara (India) 1b flower 90046-17-6 Lantana camara L., fam. Verbenaceae 2.5%
Nepeta fissa (Iran) Nepeta fissa C.A.Mey (N.microphylla Stapf, N.trautvetteri Boiss),Lamiaceae 2.7%
Geranium (India) 14a 8000-46-2 Pelargonium species, cultivar Bourbon, fam. Geraniaceae 0.1%
Santolina insularis (Italy) 1b hydrodistilled Santolina insularis L., fam. Asteraceae (Compositae) 0.3%
Licaria salicifolia Licaria salicifolia (Sw.) Kosterm., fam. Lauraceae 1.0%
Salvia pomifera Salvia pomifera L. ssp. calycina (Sm.) Hayek, fam. Lamiaceae (Labiatae) 0.01%
Cinnamomum aureofulvum bark Cinnamomum aureofulvum Gamb., fam. Lauraceae 0.8%
Geranium (Cuba) 8000-46-2 Pelargonium species, fam. Geraniaceae 0.2%
Mikania cordata leaf Mikania cordata (Burm.f.) B.L. Robinson var. cordata, fam. Asteraceae 1.6%
Nepeta betonicifolia (Turkey) Nepeta betonicifolia C.A. Meyer, fam. Lamiaceae (Labiatae) 0.1%
Hyptis suaveolens (Mali) Hyptis suaveolens (L.) Poit., fam. Lamiaceae (Labiatae) 0.5%
Cinnamon flower (India) 8007-80-5 Cinnamomum zeylanicum Blume (C. verum L. Presl), fam. Lauraceae 6.35%
Cinnamon leaf (India) 4 8007-80-5 Cinnamomum zeylanicum Blume (C. verum L. Presl), fam. Lauraceae 0.06%
Cinnamon fruit (India) 2 8007-80-5 Cinnamomum zeylanicum Blume (C. verum L. Presl), fam. Lauraceae 3.1%
Caraway herb (Mongolia) 8000-42-8 Carum carvi L., fam. Apiaceae (Umbelliferae) 1.9%
Pepper, black (India) 6a distilled 8006-82-4 Piper nigrum L., fam. Piperaceae 0.2%
Pepper, black (India) 6b free volatiles 8006-82-4 Piper nigrum L., fam. Piperaceae 0.01%
Pepper, black (India) 4 8006-82-4 Piper nigrum L., fam. Piperaceae 0.75%
Pepper, black (India) 5a 8006-82-4 Piper nigrum L., cultivar 'Karimunda', fam. Piperaceae 0.1%
Pepper, black (India) 5b 8006-82-4 Piper nigrum L., cultivar 'Kalluvally', fam. Piperaceae 0.2%
Pepper, black (India) 5c 8006-82-4 Piper nigrum L., cultivar 'Thommankodi', fam. Piperaceae 0.15%
Pepper, black (India) 5d 8006-82-4 Piper nigrum L., cultivar 'Arakulam', fam. Piperaceae 0.45%
Laurel leaf (Turkey) 4 8006-78-8 Laurus nobilis L., fam. Lauraceae 0.1%
Eucalyptus camaldulensis (Israel) Eucalyptus camaldulensis Dehn., fam. Myrtaceae 0.9%
Lemongrass (Ivory Coast) 1 8007-02-1 Cymbopogon citratus (DC) Stapf (C. flexuosus), fam. Poaceae (Gramineae) 0.35%
Santolina canescens flower Santolina canescens Lagasca, fam. Asteraceae (Compositae) 0.05%
Pinus sylvestris (Greece) 8023-99-2 Pinus sylvestris L. (Scotch pine), fam. Pinaceae 3.1%
Pinus mugo (Dwarf pine) 3 (Greece) 8000-26-8 Pinus mugo Turra, fam. Pinaceae 4.4%
Pinus pumila 2 Pinus pumila (Pall.) Regel, fam. Pinaceae 2.2%
Neomitranthes cordifolia Neomitranthes cordifolia (D. Legrand) D. Legrand, fam. Myrtaceae 2.2%
Yarrow (Estonia) 1a flower 84082-83-7 Achillea millefolium L., fam. Asteraceae (Compositae) 0.5%
Yarrow (Estonia) 1b leaf 84082-83-7 Achillea millefolium L., fam. Asteraceae (Compositae) 0.3%
Yarrow (Estonia) 1c stem 84082-83-7 Achillea millefolium L., fam. Asteraceae (Compositae) 0.1%
Achillea biebersteinii (Iran) flower Achillea biebersteinii Afan., fam. Asteraceae (Compositae) 0.1%
Achillea filipendulina (Iran) flower Achillea filipendulina Lam., fam. Asteraceae (Compositae) 0.6%
Achillea tenuifolia (Iran) flower Achillea tenuifolia Lam., fam. Asteraceae (Compositae) 0.01%
Inula verbascifolia ssp. parnassica Inula verbascifolia Hausskn., ssp. parnassia Tutin, fam. Asteraceae 0.01%
Inula verbascifolia ssp. methanea Inula verbascifolia ssp methanea (Hausskn.) Turin, fam. Asteraceae 4.7%
Laurel leaf (Mongolia) 8006-78-8 Laurus nobilis L., fam. Lauraceae 4.7%
Ferula flabelliloba Ferula flabelliloba Rech. F. et Aell., fam. Apiaceae (Umbelliferae) 12.0%
Hyssop (Yugoslavia) 1b form cyaneus 8006-83-5 Hyssopus officinalis L., f. cyaneus Alef., fam. Lamiaceae (Labiatae) 0.4%
Hyssop (Yugoslavia) 1a form albus 8006-83-5 Hyssopus officinalis L., f. albus Alef., fam. Lamiaceae (Labiatae) 0.1%