Isopropyl Myristate

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  • Identifiers

    CAS number
    110-27-0

    Molecular formula
    C17H34O2

    SMILES
    CCCCCCCCCCCCCC(=O)OC(C)C

    Safety labels

    Irritant
    Irritant

    Retention indicies (RI)

    • Carbowax: 2017.0

  • Odor profile

    Fatty 76.83%
    Waxy 71.39%
    Oily 71.11%
    Fruity 48.8%
    Creamy 43.18%
    Winey 35.82%
    Dairy 35.33%
    Cognac 34.38%
    Sweet 33.93%
    Soapy 28.73%

    Scent© AI

  • Properties

    XLogP3-AA
    7.2

    Molecular weight
    270.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • Approximately 3 °C
    • 3 °C

    Boiling point

    • 588 K (315 °C) at 760 mm Hg
    • 192.00 to 193.00 °C. @ 20.00 mm Hg

    Flash point est.
    136.37 ˚C

    Solubility expt.

    • Soluble in castor oil, cottonseed oil, acetone, chloroform, ethyl acetate, ethanol, toluene, and mineral oil; practically insoluble in glycerol, propylene glycol
    • Soluble in ether, very soluble in acetone, benzene; insoluble in water
    • insoluble in water and glycerol; soluble in alcohol

  • Synonyms

    • ISOPROPYL MYRISTATE
    • 110-27-0
    • Isopropyl tetradecanoate
    • Estergel
    • Tetradecanoic acid, 1-methylethyl ester
    • Bisomel
    • Isomyst
    • Promyr
    • Deltyl Extra
    • Kesscomir
    • Tegester
    • propan-2-yl tetradecanoate
    • Sinnoester MIP
    • Crodamol IPM
    • Plymoutm IPM
    • Starfol IPM
    • Unimate IPM
    • Kessco IPM
    • Emcol-IM
    • Wickenol 101
    • Stepan D-50
    • Emerest 2314
    • 1-Methylethyl tetradecanoate
    • Deltylextra
    • Myristic acid isopropyl ester
    • JA-FA IPM
    • Crodamol I.P.M.
    • Kessco isopropyl myristate
    • Tetradecanoic acid, isopropyl
    • FEMA No. 3556
    • Myristic acid, isopropyl ester
    • Tetradecanoic acid, isopropyl ester
    • Caswell No. 511E
    • Isopropyl myristate [USAN]
    • 1-Tridecanecarboxylic acid, isopropyl ester
    • HSDB 626
    • NSC 406280
    • UNII-0RE8K4LNJS
    • 0RE8K4LNJS
    • EINECS 203-751-4
    • MFCD00008982
    • Estergel (TN)
    • EPA Pesticide Chemical Code 000207
    • NSC-406280
    • BRN 1781127
    • methylethyl tetradecanoate
    • iso-Propyl N-tetradecanoate
    • DTXSID0026838
    • CHEBI:90027
    • EC 203-751-4
    • Tetradecanoic acid methyethyl ester
    • 1405-98-7
    • NCGC00164071-01
    • WE(2:0(1Me)/14:0)
    • isopropylmyristate
    • MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER
    • Isopropyl myristate, 98%
    • TETRADECONOIC ACID, 1-METHYLETHYL ESTER
    • DTXCID306838
    • ISOPROPYL MYRISTATE (II)
    • ISOPROPYL MYRISTATE [II]
    • ISOPROPYL MYRISTATE (MART.)
    • ISOPROPYL MYRISTATE [MART.]
    • ISOPROPYL MYRISTATE (USP-RS)
    • ISOPROPYL MYRISTATE [USP-RS]
    • CAS-110-27-0
    • ISOPROPYL MYRISTATE (EP MONOGRAPH)
    • ISOPROPYL MYRISTATE [EP MONOGRAPH]
    • IPM-EX
    • Isopropyl myristate; 1-Methylethyl tetradecanoate
    • IPM-R
    • tetradecanoic acid 1-methylethyl ester
    • Deltyextra
    • Myristic acid-isopropyl ester
    • Tegosoft M
    • Isopropyl myristate [USAN:NF]
    • Liponate IPM
    • Crodamol 1PM
    • IPM 100
    • isopropyl-myristate
    • Lexol IPM
    • Isopropyltetradecanoate
    • Radia 7190
    • Isopropyl myristate (NF)
    • Isopropyl tetradecanoic acid
    • SCHEMBL2442
    • Isopropyl myristate, >=98%
    • Isopropyl myristate (Standard)
    • CHEMBL207602
    • ISOPROPYL MYRISTATE [MI]
    • WLN: 13VOY1&1
    • FEMA 3556
    • tetradecanoic acid isopropyl ester
    • ISOPROPYL MYRISTATE [FHFI]
    • ISOPROPYL MYRISTATE [HSDB]
    • ISOPROPYL MYRISTATE [VANDF]
    • Isopropyl myristate, >=90% (GC)
    • Tox21_112080
    • Tox21_202065
    • Tox21_303171
    • ISOPROPYL MYRISTATE [WHO-DD]
    • LMFA07010677
    • NSC406280
    • s2428
    • AKOS015902296
    • Tox21_112080_1
    • DB13966
    • FI32552
    • HY-124190R
    • USEPA/OPP Pesticide Code: 000207
    • NCGC00164071-02
    • NCGC00164071-03
    • NCGC00256937-01
    • NCGC00259614-01
    • LS-14615
    • DB-040910
    • HY-124190
    • CS-0085813
    • M0481
    • NS00006471
    • Isopropyl Myristate Solution. 500mL, Sterile
    • D02296
    • F71211
    • SBI-0654218.0001
    • EN300-25299830
    • Q416222
    • SR-01000944751
    • Isopropyl myristate, Vetec(TM) reagent grade, 98%

  • Applications

    Isopropyl myristate (IPM, CAS 110-27-0) is the ester of isopropanol and myristic acid, valued in cosmetics, pharmaceuticals and technical fields for imparting a light, dry-silky emollience, acting as an oil carrier and fragrance dispersant, and markedly enhancing skin penetration; IPM improves spreadability and absorption of creams, lotions, serums, make-up and sunscreens, allowing actives such as vitamins, corticosteroids and insecticides to cross the stratum corneum; pediculicide and scabicide products use it to dissolve pyrethroids or malathion, or even alone to disrupt the lipid envelope of lice; in transdermal therapy it boosts bioavailability of nitroglycerin, ketoprofen, diclofenac and micro-encapsulated systems; perfumery and hair care benefit from its gloss-enhancing, tack-reducing finish; beyond personal care, IPM functions as an industrial lubricant, polymer plasticizer, ink and coating additive, non-toxic solvent for food extraction, antifoam agent, and compatibility enhancer with mild antimicrobial action in veterinary and agrochemical formulations.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1513.53
    methanol 1123.65
    isopropanol 2089.51
    water 0.05
    ethyl acetate 4188.76
    n-propanol 1863.57
    acetone 4304.2
    n-butanol 2043.52
    acetonitrile 1679.86
    DMF 3440.97
    toluene 1642.25
    isobutanol 1942.77
    1,4-dioxane 3531.32
    methyl acetate 2567.91
    THF 6774.31
    2-butanone 4034.35
    n-pentanol 1352.58
    sec-butanol 2203.85
    n-hexane 1372.58
    ethylene glycol 58.58
    NMP 4349.92
    cyclohexane 2972.59
    DMSO 3038.88
    n-butyl acetate 3768.61
    n-octanol 954.16
    chloroform 6970.22
    n-propyl acetate 3682.48
    acetic acid 1114.97
    dichloromethane 6728.61
    cyclohexanone 8458.72
    propylene glycol 219.12
    isopropyl acetate 3445.0
    DMAc 3483.51
    2-ethoxyethanol 1410.37
    isopentanol 2230.47
    n-heptane 728.46
    ethyl formate 1666.11
    1,2-dichloroethane 5126.66
    n-hexanol 1335.08
    2-methoxyethanol 1907.31
    isobutyl acetate 2343.04
    tetrachloromethane 1674.19
    n-pentyl acetate 3250.3
    transcutol 4931.24
    n-heptanol 805.19
    ethylbenzene 1072.83
    MIBK 3023.09
    2-propoxyethanol 1797.6
    tert-butanol 2852.8
    MTBE 4571.88
    2-butoxyethanol 1426.01
    propionic acid 1393.55
    o-xylene 1183.07
    formic acid 132.76
    diethyl ether 4195.32
    m-xylene 1133.57
    p-xylene 1581.55
    chlorobenzene 2331.21
    dimethyl carbonate 594.73
    n-octane 261.59
    formamide 289.88
    cyclopentanone 6343.18
    2-pentanone 4280.23
    anisole 1596.57
    cyclopentyl methyl ether 4961.1
    gamma-butyrolactone 5215.78
    1-methoxy-2-propanol 2090.94
    pyridine 3777.34
    3-pentanone 2991.25
    furfural 3069.46
    n-dodecane 131.48
    diethylene glycol 578.57
    diisopropyl ether 1690.93
    tert-amyl alcohol 2745.02
    acetylacetone 3527.24
    n-hexadecane 164.99
    acetophenone 1679.47
    methyl propionate 2519.08
    isopentyl acetate 3487.46
    trichloroethylene 6986.57
    n-nonanol 867.43
    cyclohexanol 3488.09
    benzyl alcohol 1012.25
    2-ethylhexanol 1389.42
    isooctanol 862.7
    dipropyl ether 2963.73
    1,2-dichlorobenzene 2307.18
    ethyl lactate 837.77
    propylene carbonate 2993.49
    n-methylformamide 1241.64
    2-pentanol 1911.85
    n-pentane 808.84
    1-propoxy-2-propanol 2001.43
    1-methoxy-2-propyl acetate 2526.63
    2-(2-methoxypropoxy) propanol 1122.05
    mesitylene 879.83
    ε-caprolactone 5944.31
    p-cymene 750.47
    epichlorohydrin 5159.79
    1,1,1-trichloroethane 5767.58
    2-aminoethanol 316.47
    morpholine-4-carbaldehyde 3312.04
    sulfolane 5910.7
    2,2,4-trimethylpentane 382.87
    2-methyltetrahydrofuran 6766.09
    n-hexyl acetate 3478.73
    isooctane 257.94
    2-(2-butoxyethoxy)ethanol 1607.16
    sec-butyl acetate 2807.61
    tert-butyl acetate 3806.46
    decalin 792.65
    glycerin 246.26
    diglyme 3335.41
    acrylic acid 739.63
    isopropyl myristate 1135.12
    n-butyric acid 3409.71
    acetyl acetate 1977.18
    di(2-ethylhexyl) phthalate 692.15
    ethyl propionate 3064.7
    nitromethane 2436.03
    1,2-diethoxyethane 3168.33
    benzonitrile 1777.88
    trioctyl phosphate 591.39
    1-bromopropane 4260.55
    gamma-valerolactone 6541.6
    n-decanol 552.76
    triethyl phosphate 1008.64
    4-methyl-2-pentanol 1131.01
    propionitrile 2047.91
    vinylene carbonate 2202.15
    1,1,2-trichlorotrifluoroethane 2646.21
    DMS 1597.29
    cumene 749.14
    2-octanol 843.41
    2-hexanone 3224.22
    octyl acetate 1347.65
    limonene 1655.6
    1,2-dimethoxyethane 3999.06
    ethyl orthosilicate 1032.86
    tributyl phosphate 836.81
    diacetone alcohol 2494.49
    N,N-dimethylaniline 1150.43
    acrylonitrile 1723.64
    aniline 1477.3
    1,3-propanediol 749.25
    bromobenzene 2867.44
    dibromomethane 5191.86
    1,1,2,2-tetrachloroethane 6785.06
    2-methyl-cyclohexyl acetate 2010.5
    tetrabutyl urea 1141.89
    diisobutyl methanol 898.09
    2-phenylethanol 992.54
    styrene 1313.77
    dioctyl adipate 1497.92
    dimethyl sulfate 1049.39
    ethyl butyrate 3050.8
    methyl lactate 703.81
    butyl lactate 1589.58
    diethyl carbonate 1449.27
    propanediol butyl ether 1082.36
    triethyl orthoformate 1944.98
    p-tert-butyltoluene 699.76
    methyl 4-tert-butylbenzoate 1488.67
    morpholine 5115.14
    tert-butylamine 2173.65
    n-dodecanol 406.63
    dimethoxymethane 2047.05
    ethylene carbonate 2356.77
    cyrene 1006.33
    2-ethoxyethyl acetate 2550.04
    2-ethylhexyl acetate 2881.67
    1,2,4-trichlorobenzene 2516.14
    4-methylpyridine 3928.33
    dibutyl ether 2965.74
    2,6-dimethyl-4-heptanol 898.09
    DEF 4466.22
    dimethyl isosorbide 2201.84
    tetrachloroethylene 4419.29
    eugenol 1065.45
    triacetin 2218.15
    span 80 1317.78
    1,4-butanediol 297.07
    1,1-dichloroethane 5573.74
    2-methyl-1-pentanol 1407.45
    methyl formate 745.85
    2-methyl-1-butanol 2003.66
    n-decane 315.7
    butyronitrile 2751.16
    3,7-dimethyl-1-octanol 1100.68
    1-chlorooctane 1284.73
    1-chlorotetradecane 402.9
    n-nonane 346.05
    undecane 186.02
    tert-butylcyclohexane 609.81
    cyclooctane 693.62
    cyclopentanol 3215.18
    tetrahydropyran 7558.22
    tert-amyl methyl ether 3274.62
    2,5,8-trioxanonane 1792.62
    1-hexene 2762.2
    2-isopropoxyethanol 1392.61
    2,2,2-trifluoroethanol 371.09
    methyl butyrate 4347.49

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Coriander fruit (Finland) 4 8008-52-4 Coriandrum sativum L., fam. Apiaceae (Umbelliferae) 0.2%