Ethyl Myristate

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  • Identifiers

    CAS number
    124-06-1

    Molecular formula
    C16H32O2

    SMILES
    CCCCCCCCCCCCCC(=O)OCC

    Retention indicies (RI)

    • DB5: 1795.0
    • Carbowax: 2034.75

  • Odor profile

    Fatty 77.95%
    Waxy 75.06%
    Oily 71.33%
    Fruity 53.58%
    Sweet 51.04%
    Creamy 45.83%
    Winey 38.22%
    Dairy 35.52%
    Cognac 35.13%
    Coconut 31.82%

    Scent© AI

  • Properties

    XLogP3-AA
    6.7

    pKa est.
    7.162202

    Molecular weight
    256.42 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 12.3 °C

    Boiling point

    • 178.00 to 180.00 °C. @ 12.00 mm Hg

    Flash point est.
    132.16 ˚C

    Solubility expt.

    • Slightly soluble in ether
    • 1ml in 1ml 95% ethanol (in ethanol)

  • Synonyms

    • Ethyl myristate
    • Ethyl tetradecanoate
    • 124-06-1
    • Tetradecanoic acid, ethyl ester
    • Myristic acid ethyl ester
    • Myristic acid, ethyl ester
    • Ethyl N-tetradecanoate
    • FEMA No. 2445
    • Ethyl myristate (natural)
    • NSC 8917
    • EINECS 204-675-4
    • MFCD00008984
    • tetradecanoic acid ethyl ester
    • Ethyl ester tetradecanoic acid
    • DTXSID6047654
    • CHEBI:84849
    • AI3-01024
    • Ethyl ester of tetradecanoic acid
    • NSC-8917
    • UNII-6995S49749
    • ETHYL MYRISTATE [FCC]
    • Tetradecanoic acid-ethyl ester
    • ETHYL MYRISTATE [FHFI]
    • DTXCID4027654
    • WE(2:0/14:0)
    • Myristic acid, ethyl ester (8CI)
    • 6995S49749
    • MYRISTIC ACID ETHYL ESTER [MI]
    • ETHYLMYRISTATE
    • SCHEMBL116495
    • ETHYL MYRISTATE [INCI]
    • Ethyl myristate, 99% (GC)
    • CHEMBL207555
    • QSPL 039
    • QSPL 070
    • QSPL 164
    • FEMA 2445
    • NSC8917
    • HMS3650O07
    • Ethyl myristate, analytical standard
    • Tox21_303520
    • AC8510
    • LMFA07010468
    • Ethyl myristate, natural, 98%, FG
    • AKOS015839783
    • Ethyl myristate, >=98%, FCC, FG
    • Ethyl tetradecanoate (ethyl myristate)
    • DS-6368
    • HY-W099586
    • NCGC00257436-01
    • CAS-124-06-1
    • SY033131
    • DB-041762
    • M0479
    • NS00012436
    • SR-01000946816
    • SR-01000946816-1
    • Q27158117
    • 204-675-4

  • Applications

    Ethyl myristate (CAS 124-06-1) is the ethyl ester of myristic acid with a pleasant, faintly coconut-like odor and finds wide application in flavor, fragrance, cosmetic, food and pharmaceutical fields: it serves as a fragrance carrier and fixative in perfumes, provides a dry, silky emollient feel in creams, lotions, lipsticks and shampoos, and acts as a solvent or penetration enhancer for lipophilic actives as well as a biodegradable lubricant in sensitive skin formulations; in food processing it contributes creamy, dairy and coconut notes and improves dispersion in fat-based systems; beyond that, ethyl myristate is employed as a green solvent for agrochemicals, as an additive in metalworking oils, as a plasticizer for biodegradable polymers and as a lipid surrogate or internal standard in biochemical research.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1079.83
    methanol 861.27
    isopropanol 1500.88
    water 0.02
    ethyl acetate 3478.69
    n-propanol 1341.1
    acetone 3438.22
    n-butanol 1473.08
    acetonitrile 1353.15
    DMF 2876.62
    toluene 1257.01
    isobutanol 1325.09
    1,4-dioxane 2934.01
    methyl acetate 2017.58
    THF 5432.57
    2-butanone 3320.39
    n-pentanol 1001.97
    sec-butanol 1558.43
    n-hexane 809.27
    ethylene glycol 39.48
    NMP 3326.92
    cyclohexane 1946.04
    DMSO 2924.1
    n-butyl acetate 3168.86
    n-octanol 633.46
    chloroform 5614.44
    n-propyl acetate 3283.67
    acetic acid 821.09
    dichloromethane 5815.05
    cyclohexanone 6789.06
    propylene glycol 144.82
    isopropyl acetate 2766.57
    DMAc 2747.52
    2-ethoxyethanol 1273.18
    isopentanol 1609.2
    n-heptane 457.72
    ethyl formate 1334.82
    1,2-dichloroethane 4459.7
    n-hexanol 941.29
    2-methoxyethanol 1609.21
    isobutyl acetate 1851.36
    tetrachloromethane 1262.5
    n-pentyl acetate 2598.74
    transcutol 4497.84
    n-heptanol 557.22
    ethylbenzene 822.88
    MIBK 2346.84
    2-propoxyethanol 1417.54
    tert-butanol 2187.05
    MTBE 3523.36
    2-butoxyethanol 1144.01
    propionic acid 1026.06
    o-xylene 890.25
    formic acid 98.41
    diethyl ether 3481.72
    m-xylene 866.47
    p-xylene 1176.48
    chlorobenzene 1920.77
    dimethyl carbonate 439.5
    n-octane 160.58
    formamide 233.82
    cyclopentanone 5355.66
    2-pentanone 3550.42
    anisole 1356.83
    cyclopentyl methyl ether 3867.1
    gamma-butyrolactone 4239.65
    1-methoxy-2-propanol 1699.15
    pyridine 3511.53
    3-pentanone 2406.36
    furfural 2686.28
    n-dodecane 77.52
    diethylene glycol 457.74
    diisopropyl ether 1207.72
    tert-amyl alcohol 1959.96
    acetylacetone 2961.86
    n-hexadecane 98.71
    acetophenone 1421.55
    methyl propionate 2004.48
    isopentyl acetate 2735.98
    trichloroethylene 6331.58
    n-nonanol 582.24
    cyclohexanol 2507.35
    benzyl alcohol 819.59
    2-ethylhexanol 984.4
    isooctanol 606.46
    dipropyl ether 2394.03
    1,2-dichlorobenzene 1886.52
    ethyl lactate 680.1
    propylene carbonate 2237.47
    n-methylformamide 1019.52
    2-pentanol 1355.01
    n-pentane 467.96
    1-propoxy-2-propanol 1623.78
    1-methoxy-2-propyl acetate 2060.55
    2-(2-methoxypropoxy) propanol 882.3
    mesitylene 651.93
    ε-caprolactone 4799.87
    p-cymene 555.47
    epichlorohydrin 4563.07
    1,1,1-trichloroethane 4676.26
    2-aminoethanol 218.8
    morpholine-4-carbaldehyde 2718.14
    sulfolane 4773.55
    2,2,4-trimethylpentane 219.56
    2-methyltetrahydrofuran 5377.59
    n-hexyl acetate 2590.97
    isooctane 157.57
    2-(2-butoxyethoxy)ethanol 1331.25
    sec-butyl acetate 2342.39
    tert-butyl acetate 2980.59
    decalin 513.33
    glycerin 184.77
    diglyme 2880.66
    acrylic acid 530.97
    isopropyl myristate 793.1
    n-butyric acid 2644.94
    acetyl acetate 1540.95
    di(2-ethylhexyl) phthalate 493.21
    ethyl propionate 2641.16
    nitromethane 2033.95
    1,2-diethoxyethane 2761.75
    benzonitrile 1496.02
    trioctyl phosphate 410.58
    1-bromopropane 3534.15
    gamma-valerolactone 5523.27
    n-decanol 361.99
    triethyl phosphate 800.96
    4-methyl-2-pentanol 807.89
    propionitrile 1704.84
    vinylene carbonate 1653.65
    1,1,2-trichlorotrifluoroethane 2277.88
    DMS 1178.64
    cumene 547.95
    2-octanol 570.79
    2-hexanone 2727.53
    octyl acetate 928.19
    limonene 1174.37
    1,2-dimethoxyethane 3645.27
    ethyl orthosilicate 814.52
    tributyl phosphate 601.24
    diacetone alcohol 1999.48
    N,N-dimethylaniline 909.91
    acrylonitrile 1485.62
    aniline 1177.59
    1,3-propanediol 545.35
    bromobenzene 2362.92
    dibromomethane 4391.38
    1,1,2,2-tetrachloroethane 5900.19
    2-methyl-cyclohexyl acetate 1531.71
    tetrabutyl urea 832.47
    diisobutyl methanol 654.07
    2-phenylethanol 781.15
    styrene 1087.4
    dioctyl adipate 1105.5
    dimethyl sulfate 804.24
    ethyl butyrate 2628.32
    methyl lactate 521.23
    butyl lactate 1247.37
    diethyl carbonate 1221.25
    propanediol butyl ether 813.98
    triethyl orthoformate 1586.88
    p-tert-butyltoluene 509.25
    methyl 4-tert-butylbenzoate 1149.3
    morpholine 4460.27
    tert-butylamine 1561.42
    n-dodecanol 264.48
    dimethoxymethane 1680.36
    ethylene carbonate 1782.99
    cyrene 798.18
    2-ethoxyethyl acetate 2132.77
    2-ethylhexyl acetate 2223.16
    1,2,4-trichlorobenzene 2017.1
    4-methylpyridine 3349.49
    dibutyl ether 2277.62
    2,6-dimethyl-4-heptanol 654.07
    DEF 3871.67
    dimethyl isosorbide 1788.11
    tetrachloroethylene 3759.78
    eugenol 853.31
    triacetin 1687.24
    span 80 1000.53
    1,4-butanediol 210.43
    1,1-dichloroethane 4557.21
    2-methyl-1-pentanol 1061.95
    methyl formate 585.3
    2-methyl-1-butanol 1455.49
    n-decane 190.47
    butyronitrile 2248.29
    3,7-dimethyl-1-octanol 733.18
    1-chlorooctane 886.42
    1-chlorotetradecane 260.23
    n-nonane 208.86
    undecane 110.34
    tert-butylcyclohexane 377.03
    cyclooctane 425.08
    cyclopentanol 2274.82
    tetrahydropyran 6237.03
    tert-amyl methyl ether 2470.97
    2,5,8-trioxanonane 1527.13
    1-hexene 1903.92
    2-isopropoxyethanol 1199.28
    2,2,2-trifluoroethanol 260.18
    methyl butyrate 3816.32

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Genet absolute 1 8023-80-1 Spartium junceum L., fam. Leguminosae (Papilionaceae) 1.91%
Nigella sativa seed Nigella sativa L., fam. Ranunculaceae 0.22%
Osmanthus absolute 68917-05-5 Osmanthus fragrans (Thunb.) Lour., fam. Oleaceae 0.2%
Rosa rugosa Rosa rugosa Thunb., var. plena Regel, fam. Rosaceae 0.01%
Etrog, leaf Citrus medica L., cultivar ethrog Engl., fam. Rutaceae 0.24%
Orange leaf, sweet (Israel) 3 Citrus sinensis (L.) Osbeck, cultivar Valencia late, fam. Rutaceae 0.03%
Orange leaf, sweet (Israel) 1 Citrus sinensis (L.) Osbeck, cultivar Jaffa (Shamouti), fam. Rutaceae 0.01%
Orange leaf, sweet (Israel) 2 Citrus sinensis (L.) Osbeck, cultivar Ruby (Blood orange), fam. Rutaceae 0.05%
Mandarin leaf (Petitgrain mandarin.) (Israel) 1 Citrus reticulata Blanco, cultivar Balady, fam. Rutaceae 0.18%
Mandarin leaf (Petitgrain mandarin.) (Israel) 2 Citrus reticulata Blanco, cultivar Yussuf Effendy, fam. Rutaceae 0.11%
Mandarin leaf (Petitgrain mandarin.) (Israel) 3 Citrus reticulata Blanco, cultivar Dancy, fam. Rutaceae 0.14%
Mandarin leaf (Petitgrain mandarin.) (Israel) 4 Citrus reticulata Blanco, cultivar Maya, fam. Rutaceae 0.05%
Mandarin leaf (Petitgrain mandarin.) (Israel) 5 Citrus reticulata Blanco, cultivar Clementine, Rutaceae 0.88%
Mandarin leaf (Petitgrain mandarin.) (Israel) 6 Citrus reticulata Blanco, cultivar Michal, fam. Rutaceae 0.41%
Mandarin leaf (Petitgrain mandarin.) (Israel) 7 Citrus reticulata Blanco, cultivar Nectarine, fam. Rutaceae 0.06%
Narcissus poeticus absolute 8023-75-4 Narcissus poeticus L., fam. Amaryllidaceae 0.1%
Coriander fruit (Finland) 1 8008-52-4 Coriandrum sativum L., fam. Apiaceae (Umbelliferae) 0.59%
Pistacia lentiscus (Israel) 1b leaf 90082-83-0 Pistacia lentiscus L., fam. Anacardiaceae 1.97%
Dendranthema vestitum flower absolute (China) Dendranthema vestitum (Hemsl.) Ling ex Shih, fam. Asteraceae (Compositae) 1.43%
Mango (India) 1a cv. Langra 90063-86-8 Mangifera indica L. cv. Langra, fam. Anacardiaceae 2.3%
Kewda (India) Pandanus fascicularis Lam., var. fascilarris, fam. Pandanaceae 0.05%
Soursop, fruit Annona muricata L., fam. Annonaceae 0.05%
Geneps fruit (Cuba) Melicocca bijuga L., fam. Sapindaceae 0.01%
Soursop, wild fruit Annona montana Macf., fam. Annonaceae 0.01%
Ambarella fruit (Brazil) Spondias cytherea Sonnerat, fam. Anarcardiaceae 0.05%