gamma-EUDESMOL

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  • Identifiers

    CAS number
    1209-71-8

    Molecular formula
    C15H26O

    SMILES
    CC1=C2C[C@@H](CC[C@]2(CCC1)C)C(C)(C)O

    Retention indicies (RI)

    • DB5: 1620.0
    • Carbowax: 2098.0

  • Odor profile

    Woody 81.71%
    Sweet 62.28%
    Floral 62.06%
    Amber 46.88%
    Musk 42.3%
    Balsamic 41.04%
    Powdery 40.87%
    Dry 40.25%
    Spicy 35.99%
    Waxy 35.24%

    Scent© AI

  • Properties

    XLogP3-AA
    3.4

    Molecular weight
    222.37 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    312°C

    Flash point est.
    115.3 ˚C

  • Synonyms

    • gamma-Eudesmol
    • Machilol
    • Selinenol
    • 1209-71-8
    • Uncineol
    • eudesm-4-en-11-ol
    • .gamma.-Eudesmol
    • 2-[(2R,4aR)-4a,8-dimethyl-2,3,4,5,6,7-hexahydro-1H-naphthalen-2-yl]propan-2-ol
    • (+)-gamma-eudesmol
    • C3M974G2BE
    • CHEBI:62513
    • DTXSID301017639
    • Gamma-Eudesmol (>85%)
    • (2R-cis)-1,2,3,4,4a,5,6,7-Octahydro-alpha,alpha,4a,8-tetramethyl-2-naphthalenemethanol
    • 2-((2R,4aR)-4a,8-Dimethyl-1,2,3,4,4a,5,6,7-octahydronaphthalen-2-yl)propan-2-ol
    • 2-Naphthalenemethanol, 1,2,3,4,4a,5,6,7-octahydro-alpha,alpha,4a,8-tetramethyl-, (2R-cis)-
    • 2-Naphthalenemethanol, 1,2,3,4,4a,5,6,7-octahydro-.alpha.,.alpha.,4a,8-tetramethyl-, (2R-cis)-
    • .gamma.-Eudesmole
    • 2-[(2R,4aR)-4a,8-dimethyl-1,2,3,4,4a,5,6,7-octahydronaphthalen-2-yl]propan-2-ol
    • 2-((4aR)-1,2,3,4,4alpha,5,6,7-octahydro-4alpha,8-dimethylnaphthalen-2-yl)-propan-2-ol
    • EUDESMOL, gamma-
    • UNII-C3M974G2BE
    • EUDESMOL, .GAMMA.-
    • SCHEMBL194293
    • CHEMBL477900
    • (+)-.GAMMA.-EUDESMOL
    • DTXCID001475824
    • [2R-cis]-1,2,3,4,4a,5,6,7-Octahydro-.alpha.,.alpha.,4a,8-tetramethyl-2-naphthalenemethanol
    • HY-N0065
    • CS-0007112
    • NS00126364
    • C17124
    • Q27131974
    • (2R,4AR)-1,2,3,4,4A,5,6,7-OCTAHYDRO-.ALPHA.,.ALPHA.,4A,8-TETRAMETHYL-2-NAPHTHALENEMETHANOL
    • (2R,4AR)-1,2,3,4,4A,5,6,7-OCTAHYDRO-alpha,alpha,4A,8-TETRAMETHYL-2-NAPHTHALENEMETHANOL
    • 2-NAPHTHALENEMETHANOL, 1,2,3,4,4A,5,6,7-OCTAHYDRO-.ALPHA.,.ALPHA.,4A,8-TETRAMETHYL-, (2R,4AR)-
    • 2-NAPHTHALENEMETHANOL, 1,2,3,4,4A,5,6,7-OCTAHYDRO-alpha,alpha,4A,8-TETRAMETHYL-, (2R,4AR)-

  • Applications

    gamma-EUDESMOL (CAS 1209-71-8) is a sesquiterpene alcohol with a warm, woody, slightly sweet odor, used primarily in perfumery and fragrances to impart and reinforce woody–earthy facets, add depth and longevity, and act as a fixative in fine fragrances, soaps, personal care, scented candles, and home care products; in analytics and quality control it is employed as a GC–MS reference standard for identification/quantification, supporting essential‑oil fingerprinting (notably oils rich in eudesmols such as agarwood and Atractylodes) and monitoring compositional variation by origin, season, and processing; in research, gamma‑eudesmol serves as a model component to study sesquiterpene biosynthesis, chiral separations, and in‑vitro bioactivity screening (e.g., anti‑inflammatory, antimicrobial, antioxidant, or insect‑repellent effects), and it can be leveraged as a synthetic intermediate toward related woody odorants; overall, gamma‑eudesmol is valued as a natural woody note builder, a chemical marker in botanicals/essential oils, and a method standard in analytical chemistry.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 370.52
    methanol 383.58
    isopropanol 283.37
    water 0.71
    ethyl acetate 459.61
    n-propanol 324.64
    acetone 461.87
    n-butanol 327.47
    acetonitrile 416.14
    DMF 480.41
    toluene 473.96
    isobutanol 199.46
    1,4-dioxane 1321.75
    methyl acetate 398.33
    THF 1682.42
    2-butanone 421.91
    n-pentanol 143.06
    sec-butanol 177.66
    n-hexane 33.35
    ethylene glycol 27.45
    NMP 340.79
    cyclohexane 122.86
    DMSO 221.55
    n-butyl acetate 490.4
    n-octanol 148.59
    chloroform 1042.22
    n-propyl acetate 233.78
    acetic acid 176.9
    dichloromethane 797.02
    cyclohexanone 600.45
    propylene glycol 57.58
    isopropyl acetate 314.9
    DMAc 347.48
    2-ethoxyethanol 189.79
    isopentanol 243.66
    n-heptane 56.36
    ethyl formate 254.19
    1,2-dichloroethane 392.97
    n-hexanol 376.69
    2-methoxyethanol 405.39
    isobutyl acetate 201.56
    tetrachloromethane 150.97
    n-pentyl acetate 252.08
    transcutol 1292.33
    n-heptanol 164.36
    ethylbenzene 156.76
    MIBK 233.29
    2-propoxyethanol 554.33
    tert-butanol 317.69
    MTBE 370.78
    2-butoxyethanol 289.44
    propionic acid 169.8
    o-xylene 202.41
    formic acid 54.18
    diethyl ether 476.9
    m-xylene 264.8
    p-xylene 223.47
    chlorobenzene 409.59
    dimethyl carbonate 142.13
    n-octane 18.56
    formamide 111.52
    cyclopentanone 676.79
    2-pentanone 352.67
    anisole 328.74
    cyclopentyl methyl ether 508.62
    gamma-butyrolactone 652.69
    1-methoxy-2-propanol 337.59
    pyridine 769.08
    3-pentanone 262.74
    furfural 512.15
    n-dodecane 14.08
    diethylene glycol 237.47
    diisopropyl ether 142.9
    tert-amyl alcohol 178.76
    acetylacetone 390.59
    n-hexadecane 16.91
    acetophenone 244.95
    methyl propionate 302.44
    isopentyl acetate 444.8
    trichloroethylene 773.33
    n-nonanol 140.18
    cyclohexanol 263.36
    benzyl alcohol 192.97
    2-ethylhexanol 213.02
    isooctanol 126.68
    dipropyl ether 369.21
    1,2-dichlorobenzene 309.16
    ethyl lactate 89.12
    propylene carbonate 347.27
    n-methylformamide 231.92
    2-pentanol 159.56
    n-pentane 45.43
    1-propoxy-2-propanol 416.38
    1-methoxy-2-propyl acetate 491.84
    2-(2-methoxypropoxy) propanol 290.24
    mesitylene 159.5
    ε-caprolactone 486.78
    p-cymene 137.65
    epichlorohydrin 684.29
    1,1,1-trichloroethane 425.21
    2-aminoethanol 95.29
    morpholine-4-carbaldehyde 616.39
    sulfolane 385.4
    2,2,4-trimethylpentane 23.28
    2-methyltetrahydrofuran 824.66
    n-hexyl acetate 358.72
    isooctane 22.79
    2-(2-butoxyethoxy)ethanol 408.67
    sec-butyl acetate 179.3
    tert-butyl acetate 325.16
    decalin 40.23
    glycerin 76.03
    diglyme 778.13
    acrylic acid 125.62
    isopropyl myristate 143.66
    n-butyric acid 329.62
    acetyl acetate 294.29
    di(2-ethylhexyl) phthalate 144.67
    ethyl propionate 199.81
    nitromethane 386.38
    1,2-diethoxyethane 539.0
    benzonitrile 367.52
    trioctyl phosphate 97.02
    1-bromopropane 304.16
    gamma-valerolactone 877.42
    n-decanol 100.83
    triethyl phosphate 131.77
    4-methyl-2-pentanol 115.04
    propionitrile 423.65
    vinylene carbonate 382.31
    1,1,2-trichlorotrifluoroethane 288.32
    DMS 250.61
    cumene 102.39
    2-octanol 98.95
    2-hexanone 218.53
    octyl acetate 172.51
    limonene 179.35
    1,2-dimethoxyethane 515.8
    ethyl orthosilicate 137.7
    tributyl phosphate 117.97
    diacetone alcohol 254.74
    N,N-dimethylaniline 189.65
    acrylonitrile 384.5
    aniline 376.57
    1,3-propanediol 184.73
    bromobenzene 446.69
    dibromomethane 491.83
    1,1,2,2-tetrachloroethane 542.55
    2-methyl-cyclohexyl acetate 249.52
    tetrabutyl urea 142.52
    diisobutyl methanol 130.13
    2-phenylethanol 297.88
    styrene 198.26
    dioctyl adipate 189.72
    dimethyl sulfate 139.86
    ethyl butyrate 306.23
    methyl lactate 118.2
    butyl lactate 181.96
    diethyl carbonate 198.6
    propanediol butyl ether 219.53
    triethyl orthoformate 234.33
    p-tert-butyltoluene 147.08
    methyl 4-tert-butylbenzoate 245.34
    morpholine 1199.73
    tert-butylamine 237.65
    n-dodecanol 74.6
    dimethoxymethane 504.45
    ethylene carbonate 322.99
    cyrene 197.87
    2-ethoxyethyl acetate 366.37
    2-ethylhexyl acetate 356.25
    1,2,4-trichlorobenzene 349.16
    4-methylpyridine 705.11
    dibutyl ether 225.25
    2,6-dimethyl-4-heptanol 130.13
    DEF 318.89
    dimethyl isosorbide 540.94
    tetrachloroethylene 335.65
    eugenol 225.02
    triacetin 300.14
    span 80 262.85
    1,4-butanediol 44.36
    1,1-dichloroethane 423.15
    2-methyl-1-pentanol 128.01
    methyl formate 177.07
    2-methyl-1-butanol 186.48
    n-decane 28.02
    butyronitrile 441.5
    3,7-dimethyl-1-octanol 157.31
    1-chlorooctane 109.17
    1-chlorotetradecane 41.96
    n-nonane 25.39
    undecane 18.86
    tert-butylcyclohexane 37.55
    cyclooctane 39.53
    cyclopentanol 240.09
    tetrahydropyran 1118.71
    tert-amyl methyl ether 210.38
    2,5,8-trioxanonane 503.59
    1-hexene 115.33
    2-isopropoxyethanol 153.19
    2,2,2-trifluoroethanol 62.11
    methyl butyrate 245.06

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Amyris 1 8015-65-4 Amyris balsamifera L., fam. Rutaceae 10.9%
Citronella java (China) 8000-29-1 Cymbopogon winterianus Jowitt., fam. Poaceae (Gramineae) 0.59%
Citronella java (Argentina) 2 8000-29-1 Cymbopogon winterianus Jowitt., fam. Poaceae (Gramineae) 0.31%
Citronella java (S. America) 8000-29-1 Cymbopogon winterianus Jowitt., fam. Poaceae (Gramineae) 0.37%
Citronella java 3 8000-29-1 Cymbopogon winterianus Jowitt., fam. Poaceae (Gramineae) 0.17%
Citronella ceylon 5 8000-29-1 Cymbopogon nardus (L.) Rendle, fam. Poaceae (Gramineae) 0.23%
Geranium (Algeria) 1 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 5.41%
Geranium (Algeria) 2 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 4.2%
Geranium, Bourbon 1 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 2.03%
Geranium (China) 1 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 2.03%
Geranium (Egypt) 1 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 4.62%
Geranium (Egypt) 2 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 4.0%
Geranium (India) 1 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 4.57%
Geranium (India) 2 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 14.49%
Geranium (Morocco) 1 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 5.2%
Geranium (Morocco) 2 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 5.1%
Rose (Turkey) 6 8007-01-0 Rosa damascena Mill., fam. Rosaceae 0.04%
Guaiacwood 2 8016-23-7 Bulnesia sarmienti Lorentz ex Griseb, fam. Zygophyllaceae 2.21%
Geranium (Rwanda) 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 3.23%
Amyris 2 8015-65-4 Amyris balsamifera L., fam. Rutaceae 0.97%
Geranium, Bourbon 6 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 1.05%
Geranium 2 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 4.87%
Geranium (Egypt) 3 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 4.7%
Geranium (India) 8 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 4.0%
Geranium (Egypt) 4 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 5.71%
Tagetes (Argentina) 2b 8016-84-0 Tagetes minuta L. (Marigold), fam. Asteraceae (Compositae) 0.01%
Geranium (Egypt) 5 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 5.5%
Geranium (Morocco) 3 8000-46-2 Pelargonium graveolens L'Herti. ex Aiton, fam. Geraniaceae 2.5%
Orange leaf, sweet (Mauritius) Citrus sinensis (L.) Osbeck, fam. Rutaceae 0.13%
Phoebe 1 Phoebe porosa Mez. (syn. Oreodaphne porosa Nees et Mart.), fam. Lauraceae 1.2%
Phoebe 2 Phoebe porsa Mez. (syn. Oreodaphne prosa Nees & Mart.), fam. Lauraceae 2.6%
Thymus funkii Thymus funkii Cosson, fam. Lamiaceae (Labiatae) 0.15%
Leptospermum javanicum (Malaysia) Leptospermum javanicum Blume, fam. Myrtaceae 1.0%
Citrus japonica peel (Vietnam) Citrus japonica L., fam. Rutaceae 0.05%
Ginger (Tahiti) 8007-08-7 Zingiber officinale Roscoe, fam. Zingiberaceae 0.4%
Cinnamon fruit (India) 1 8007-80-5 Cinnamomum zeylanicum Blume (C. verum L. Presl), fam. Lauraceae 0.45%
Wormwood (Mugwort) 2 8008-93-3 Artemisia absinthium L., fam. Asteraceae (Compositae) 1.5%
Helichrysum italicum 1a 8023-95-8 Helichrysum italicum (Roth) G. Don ssp. italicum, fam. Asteraceae 0.11%
Helichrysum italicum 1b 8023-95-8 Helichrysum italicum ssp. microphyllum (Willd.) Nyman, fam. Asteraceae 0.15%
Geranium (India) 9 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 4.2%
Lime (Mexican, West Indian, Key) 7 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 0.07%
Geranium (India) 10 8000-46-2 Pelargonium species, fam. Geraniaceae 10.0%
Geranium (India) 11 8000-46-2 Pelargonium species, fam. Geraniaceae 5.7%
Helichrysum stoechas (France) 8023-85-8 Helichrysum stoechas L., fam. Asteraceae (Compositae) 0.2%
Bupleurum gibraltarium (Spain) Bupleurum gibraltarium Lam., fam. Apiaceae (Umbelliferae) 0.8%
Guava fruit (Reunion island) 91770-12-6 Psidium guajava L., fam. Myrtaceae 0.1%
Turmeric (India) 5a rhizome 8024-37-1 Curcuma longa L., cv. Roma (C. domestica Val.), fam. Zingiberaceae 0.4%
Helichrysum italicum (France-Corsica) 8025-95-8 Helichyrsum italicum (Roth) G. Don ssp.italicum, fam. Asteraceae (Compos.) 0.1%
Geranium (India) 14a 8000-46-2 Pelargonium species, cultivar Bourbon, fam. Geraniaceae 5.6%
Geranium (India) 14b 8000-46-2 Pelargonium species, cultivar Bourbon, fam. Geraniaceae 7.6%