Farnesol, (2Z,6Z)-

  • Identifiers

    CAS number
    16106-95-9

    Molecular formula
    C15H26O

    SMILES
    CC(=CCC/C(=C\CC/C(=C\CO)/C)/C)C
    HO

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

    Retention indicies (RI)

    • DB5: 1715.75
    • Carbowax: 2268.5

  • Odor profile

    floral 90.45%
    rose 65.81%
    waxy 64.52%
    sweet 60.12%
    citrus 50.64%
    green 48.91%
    fruity 48.09%
    fresh 47.42%
    balsamic 46.27%
    muguet 42.06%

    Scent© AI

  • Properties

    XLogP3-AA
    4.8 Well soluble in BB, DEP, IPM

    Molecular weight
    222.37 g/mol

    Vapor pressure est.

    • 0 hPa @ 20°C
    • 0 hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting points

    • < 25 °C

    Boiling points

    • 230 to 235 °F at 760 mmHg (NTP, 1992)
    • 111 °C at 3.50E-01 mm Hg
    • 110-113 °C
    • BP: 145-146 °C at 3 mm Hg

    Solubilities

    • Soluble in three volumes of 70% alcohol
    • SOL IN ALCOHOL: 1:3 IN 70% ALCOHOL
    • Solubility in alcohol: 1 mL in 1 mL 95% ethanol
    • Insoluble in water
    • Insoluble in water; soluble in oils
    • soluble (in ethanol)

  • Synonyms

    • cis,cis-Farnesol
    • (Z,Z)-farnesol
    • farnesol
    • cis-Farnesol
    • (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
    • 16106-95-9
    • (2-cis,6-cis)-farnesol
    • Farnesol, (2Z,6Z)-
    • z,z-farnesol
    • 2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-, (2Z,6Z)-
NaN -Infinity

IFRA Standard - 51

Recommendation
Restriction / Specification
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 0.21 % Category 7A
Rinse-off products applied to the hair with some hand contact
 2.4 %
Category 2
Products applied to the axillae
 0.062 % Category 7B
Leave-on products applied to the hair with some hand contact
 2.4 %
Category 3
Products applied to the face/body using fingertips
 1.2 % Category 8
Products with significant anogenital exposure
 0.12 %
Category 4
Products related to fine fragrance
 1.2 % Category 9
Products with body and hand exposure, primarily rinse off
 2.3 %
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 0.29 % Category 10A
Household care products with mostly hand contact
 8.1 %
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 0.29 % Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 8.1 %
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 0.29 % Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 4.5 %
Category 5D
Baby Creams, baby Oils and baby talc
 0.29 % Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 4.5 %
Category 6
Products with oral and lip exposure
 0.68 % Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Specification
Farnesol should only be used as a fragrance ingredient if it contains a minimum of 96% of farnesol isomers as determined by GLC.

Botanical

Name CAS Botanical Proportion
Juniperus rigida (Japan) 2 Juniperus rigida Mig., fam. Cupressaceae 0.05%
Juniperus rigida (China) Juniperus rigida Mig., fam. Cupressaceae 0.05%
Juniperus rigida (Korea) Juniperus rigida Mig., fam. Cupressaceae 0.05%
Eucalyptus tereticornis (Benin) Eucalyptus tereticornis Smith, fam. Myrtaceae 8.42%
Rose (China) 1a 8007-01-0 Rosa damascena Mill., fam. Rosaceae 0.21%
Rose (China) 1b 8007-01-0 Rosa species (France), fam. Rosaceae 0.27%
Rose (China) 1c 8007-01-0 Rosa damascena Mill., fam. Rosaceae 0.27%
Rose (China) 1d 8007-01-0 Rosa species (Moroccan), fam. Rosaceae 0.23%
Clementine x Lemon (Italy) 2 Citrus clementina Hort. ex Tan. x Citrus limon (L.) Burm., fam. Rutaceae 0.04%
Canella winterana (Cuba) 2 Canella winterana (L.) Gaertn., fam. Canellaceae 0.3%
Cypress, Leyland (Poland) Cupressocyparis leylandii (Dall. et Jacks.) Dall., fam. Cupressaceae 0.1%
Couroupita guianensis flower (Brazil) Couroupita guainensis Auble., fam. Lecythidaceae 1.0%
Palmarosa (India) 8 8014-19-5 Cymbopogon martini (Roxb.) Wats, var. motia Burk., fam. Poaceae 0.5%
Palmarosa (India) 10a Spikelet 8014-19-5 Cymbopogon martini (Roxb.) Wats, var. motia, fam. Poaceae (Gramineae) 0.09%
Palmarosa (India) 10b Raceme 8014-19-5 Cymbopogon martini (Roxb.) Wats, var. motia, fam. Poaceae (Gramineae) 0.05%
Palmarosa (India) 10c Spathe 8014-19-5 Cymbopogon martini (Roxb.) Wats, var. motia, fam. Poaceae (Gramineae) 0.16%
Cinnamomum aureofulvum leaf Cinnamomum aureofulvum Gamb., fam. Lauraceae 0.3%
Cinnamomum aureofulvum bark Cinnamomum aureofulvum Gamb., fam. Lauraceae 0.3%
Pepper, black (India) 6a distilled 8006-82-4 Piper nigrum L., fam. Piperaceae 0.3%
Pepper, black (India) 6b free volatiles 8006-82-4 Piper nigrum L., fam. Piperaceae 1.0%
Yarrow (Estonia) 1a flower 84082-83-7 Achillea millefolium L., fam. Asteraceae (Compositae) 0.25%
Yarrow (Estonia) 1b leaf 84082-83-7 Achillea millefolium L., fam. Asteraceae (Compositae) 0.15%
Yarrow (Estonia) 1c stem 84082-83-7 Achillea millefolium L., fam. Asteraceae (Compositae) 0.3%
Cymbopogon olivieri (Iran) Cymbopogon olivieri (Boiss.) Bor, fam. Poaceae (Gramineae) 0.1%
Elionurus muticus (Zimbabwe) Elionurus muticus (Spreng.) Kunth, fam. Poaceae (Gramineae) 0.4%