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Vertofix Coeur aka. Methyl Cedryl Ketone Aroma Chemical
CAS# 32388-55-9

Woody, Amber, Musk, Dry, Cedar

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Vertofix Coeur is a semi-synthetic ingredient that plays an important role in the fragrance industry and is widely known under the proprietary trade name of IFF. Chemically, it is called Methyl Cedryl Ketone or Acetyl Cedrene, and it may also appear under other names such as Cedryl Methyl Ketone or Lignofix. Presented as a medium-viscosity liquid with a color ranging from pale yellow to amber, Vertofix Coeur is produced from cedrene, a natural sesquiterpene fractionated from Virginia cedarwood or Chinese cedarwood essential oil. It emerged in the mid-20th century out of a practical need for a woody note that was more tenacious, stable, and deeper than natural essential oils. Through the acetylation of cedrene, chemists not only preserved the original woody character but also introduced warm musky and ambery facets. Notably, IFF carried out careful refinement to remove undesirable impurities, creating the “Coeur” version-coeur meaning “heart”-to represent the highest-quality core fraction. This advancement made the material a gold standard among synthetic woody notes before Iso E Super came to dominate the market, and it helped define a solid backbone in modern perfumery.

Description

Belonging to the woody family with distinct amber and leathery aspects, Vertofix Coeur functions as an excellent base note and fixative. Its scent is very rich, dry, and warm, marked by a cedarwood signature that is smoother and interwoven with a gentle leather nuance. Compared to its familiar counterpart Iso E Super, it feels more closed and deeper-less airy, but noticeably more grounded. Although its odor intensity is only moderate, its longevity is extremely high, making it valuable for building crisp woody accords, especially cedarwood and reconstructed sandalwood effects. It is also a key material for constructing a masculine leather note, and it acts as a foundation that makes florals such as rose or iris feel warmer and last longer on skin. In practical composition, combining Vertofix with Iso E Super creates a classic modern woody mass: Iso E Super provides diffusion, while Vertofix supplies depth and persistence. With α- or β-ionones, it produces a refined woody-powdery effect often found in violet or iris-centered fragrances; with vetiver, it can soften smoky facets and rough earthy edges. Thanks to its good solubility in alcohol and common solvents, it is typically used directly during blending.

Applications

Vertofix Coeur is broadly used across many categories, from men’s fragrances in the Woody, Leather, and Fougère families to unisex styles. It also appears widely in cosmetics and personal care products such as bar soap, shower gel, and deodorants, as well as home-fragrance products like scented candles to create a warm, cozy feel. Because it is highly chemically stable in alkaline environments, it is an ideal choice for detergents. In terms of safety, it is generally regarded as skin-friendly, with low irritation potential and a low sensitization profile, and it is not currently subject to any specific IFRA concentration limit related to toxicity. Typical use levels in fine fragrance range from 1% to 10%, and can be pushed to around 20% in strongly woody formulas. For handling, it should be stored in a dry, cool place away from direct light, and care should be taken to ensure the cedrene feedstock is clearly sourced to avoid impurity carryover. In the market, Vertofix is found in many fragrances featuring modern cedarwood or leather facets, for example Chanel No. 19 (a cool, dry woody base with iris) and Estée Lauder White Linen (a clean, dry woody impression). Finally, its value was noted by expert Steffen Arctander in his monograph No. 40 under the name Acetyl cedrene: he described it as a warm, deep woody odor with an amber-like character, used as a fixative and modifier for woody and spicy types, in Chypre, Fougère, and Oriental bases, and particularly compatible with ionones, patchouli, bergamot, and macrocyclic musks.

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Technical standards

Physical appearance Transparent liquid Conform
Color Pale yellow to brownish Conform
Specific Gravity @20˚C 0.999 → 1.009 1.0051
Refractive Index @20˚C 1.515 → 1.52 1.5189
Acid value (mgKOH/g) ≤ 1.0 0.1
CUPARENE 0% → 5% 0%
FUNEDRENE 0% → 10% 6.44%
CEDRYL METHYL KETONE 36% → 60% 46.43%

Solubility @25˚C

Solvent Solubility (g/L)
ethanol 79.52
methanol 97.05
isopropanol 112.15
water 1.42
ethyl acetate 177.98
n-propanol 100.3
acetone 254.16
n-butanol 107.17
acetonitrile 211.04
DMF 404.37
toluene 443.39
isobutanol 87.46
1,4-dioxane 464.17
methyl acetate 191.14
THF 870.36
2-butanone 227.48
n-pentanol 48.85
sec-butanol 68.1
n-hexane 5.61
ethylene glycol 22.0
NMP 336.43
cyclohexane 30.02
DMSO 112.06
n-butyl acetate 144.12
n-octanol 45.77
chloroform 842.58
n-propyl acetate 104.73
acetic acid 82.05
dichloromethane 611.0
cyclohexanone 440.79
propylene glycol 32.45
isopropyl acetate 151.03
DMAc 229.36
2-ethoxyethanol 68.22
isopentanol 90.74
n-heptane 8.51
ethyl formate 124.31
1,2-dichloroethane 283.87
n-hexanol 95.52
2-methoxyethanol 175.74
isobutyl acetate 97.2
tetrachloromethane 121.97
n-pentyl acetate 109.4
transcutol 192.21
n-heptanol 59.05
ethylbenzene 126.76
MIBK 142.97
2-propoxyethanol 199.1
tert-butanol 113.51
MTBE 99.78
2-butoxyethanol 109.27
propionic acid 90.34
o-xylene 195.68
formic acid 31.01
diethyl ether 106.74
m-xylene 262.35
p-xylene 189.31
chlorobenzene 373.75
dimethyl carbonate 110.96
n-octane 4.61
formamide 68.93
cyclopentanone 618.39
2-pentanone 180.59
anisole 211.71
cyclopentyl methyl ether 261.91
gamma-butyrolactone 570.57
1-methoxy-2-propanol 178.03
pyridine 568.54
3-pentanone 141.14
furfural 456.84
n-dodecane 4.45
diethylene glycol 124.72
diisopropyl ether 47.89
tert-amyl alcohol 65.41
acetylacetone 262.93
n-hexadecane 5.53
acetophenone 193.57
methyl propionate 159.34
isopentyl acetate 158.36
trichloroethylene 636.39
n-nonanol 48.32
cyclohexanol 134.86
benzyl alcohol 160.59
2-ethylhexanol 63.52
isooctanol 51.17
dipropyl ether 64.8
1,2-dichlorobenzene 311.8
ethyl lactate 59.31
propylene carbonate 267.41
n-methylformamide 165.96
2-pentanol 68.14
n-pentane 9.89
1-propoxy-2-propanol 140.91
1-methoxy-2-propyl acetate 197.91
2-(2-methoxypropoxy) propanol 103.86
mesitylene 134.65
ε-caprolactone 323.48
p-cymene 79.52
epichlorohydrin 508.64
1,1,1-trichloroethane 359.88
2-aminoethanol 48.91
morpholine-4-carbaldehyde 390.54
sulfolane 341.67
2,2,4-trimethylpentane 7.97
2-methyltetrahydrofuran 361.39
n-hexyl acetate 140.23
isooctane 7.86
2-(2-butoxyethoxy)ethanol 120.18
sec-butyl acetate 90.27
tert-butyl acetate 151.63
decalin 16.53
glycerin 52.01
diglyme 232.49
acrylic acid 90.82
isopropyl myristate 61.74
n-butyric acid 148.2
acetyl acetate 166.68
di(2-ethylhexyl) phthalate 79.77
ethyl propionate 104.53
nitromethane 242.06
1,2-diethoxyethane 103.7
benzonitrile 295.38
trioctyl phosphate 50.17
1-bromopropane 150.63
gamma-valerolactone 633.17
n-decanol 35.9
triethyl phosphate 63.27
4-methyl-2-pentanol 54.32
propionitrile 183.97
vinylene carbonate 312.66
1,1,2-trichlorotrifluoroethane 217.73
DMS 174.79
cumene 77.66
2-octanol 40.21
2-hexanone 106.5
octyl acetate 74.36
limonene 84.69
1,2-dimethoxyethane 168.02
ethyl orthosilicate 61.35
tributyl phosphate 56.34
diacetone alcohol 138.45
N,N-dimethylaniline 125.63
acrylonitrile 255.5
aniline 287.25
1,3-propanediol 91.38
bromobenzene 439.49
dibromomethane 340.89
1,1,2,2-tetrachloroethane 415.79
2-methyl-cyclohexyl acetate 126.52
tetrabutyl urea 72.63
diisobutyl methanol 44.69
2-phenylethanol 213.36
styrene 154.1
dioctyl adipate 87.5
dimethyl sulfate 141.63
ethyl butyrate 110.11
methyl lactate 85.97
butyl lactate 92.4
diethyl carbonate 84.33
propanediol butyl ether 80.4
triethyl orthoformate 84.92
p-tert-butyltoluene 79.32
methyl 4-tert-butylbenzoate 161.32
morpholine 415.21
tert-butylamine 72.66
n-dodecanol 26.68
dimethoxymethane 280.62
ethylene carbonate 239.51
cyrene 139.41
2-ethoxyethyl acetate 165.93
2-ethylhexyl acetate 126.93
1,2,4-trichlorobenzene 343.21
4-methylpyridine 568.36
dibutyl ether 46.67
2,6-dimethyl-4-heptanol 44.69
DEF 167.05
dimethyl isosorbide 246.47
tetrachloroethylene 270.84
eugenol 149.39
triacetin 143.15
span 80 103.73
1,4-butanediol 28.37
1,1-dichloroethane 307.89
2-methyl-1-pentanol 50.34
methyl formate 148.12
2-methyl-1-butanol 73.57
n-decane 7.62
butyronitrile 173.21
3,7-dimethyl-1-octanol 53.5
1-chlorooctane 36.85
1-chlorotetradecane 16.36
n-nonane 6.1
undecane 5.69
tert-butylcyclohexane 14.02
cyclooctane 10.3
cyclopentanol 154.8
tetrahydropyran 371.19
tert-amyl methyl ether 68.28
2,5,8-trioxanonane 155.96
1-hexene 28.47
2-isopropoxyethanol 61.57
2,2,2-trifluoroethanol 61.07
methyl butyrate 129.65

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  • CAS NUMBER

    32388-55-9

  • FAMILIES

    Wood

  • BRAND

    IFF

  • EVAPORATION RATE

    Ultra slow

  • Odor impact

    Medium est.

  • FLASH POINT

    134.99 ˚C est.

base
Woody
Amber
Musk
Dry
Cedar
Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
No restriction
Category 2
Products applied to the axillae
No restriction Category 7B
Leave-on products applied to the hair with some hand contact
No restriction
Category 3
Products applied to the face/body using fingertips
No restriction Category 8
Products with significant anogenital exposure
No restriction
Category 4
Products related to fine fragrance
No restriction Category 9
Products with body and hand exposure, primarily rinse off
No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
No restriction Category 10A
Household care products with mostly hand contact
No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
No restriction
Category 5D
Baby Creams, baby Oils and baby talc
No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
No restriction
Category 6
Products with oral and lip exposure
No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
No restriction
  • All orders will be processed within 1-2 business days from the time the order is confirmed.
  • Free shipping is available for international retail orders valued at 500 USD or more.
  • Delivery time is 1-3 business days for local areas, 3-7 days for suburban and nationwide deliveries, and 1-4 weeks for international orders.
  • You have 30 days from the date of receipt to initiate the return process.
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  • Certificate of Analysis (COA)

    Provides information on the physical and chemical properties of the product.
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  • IFRA Certificate of Conformity

    Sets safety standards and guidelines for the product in manufacturing.
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  • Safety Data Sheet (SDS)

    Provides important safety guidelines for transporting, storing, and using the product.
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