1 1

Macrolide Supra alt. Exaltolide Total Aroma Chemical
CAS# 106-02-5

Musk, Sweet, Animal, Powdery, Waxy

$7
$0 $7
Sale Sold out
Size

Macrolide Supra (CAS# 106-02-5) is a high-grade macrocyclic musk (macrocyclic lactone), also known as Pentadecan-15-olide, Exaltolide or omega-Pentadecalactone. It is a synthetic musk with a structure related to natural musk components found in ambrette seed and angelica root extracts, offering high purity, excellent stability and a significantly better biodegradability profile than many traditional musk types.

Its odour profile is musky and lactonic, soft and highly refined: a clean, slightly powdery musk with a warm aura, highlighted by gentle floral nuances, hints of red fruits and a light vanillic sweetness. At low dosage it gives a smooth “skin-scent” effect that feels intimate and enveloping; at higher levels it brings volume, depth and a luxurious, long-lasting musky warmth to the entire composition.

In perfumery and fragrance applications, Macrolide Supra is used as a key base note and fixative, especially effective in white floral, powdery, woody, red-fruity, chypre and gourmand creations. It performs very well in combination with other macrocyclic musks, sandalwood and cedarwood notes, patchouli, ambroxide and various lactones (peach, apricot, milky facets), adding roundness, softness and greatly enhancing diffusion and substantivity on skin, hair, textiles and in home fragrance products such as fabric softeners, detergents, room sprays, candles and soaps.

Macrolide Supra is a colourless to white solid at room temperature that can be gently melted or pre-diluted for easier handling. It is readily soluble in standard perfumery solvents and is typically used from trace amounts up to a few percent of the concentrate, depending on the desired impact and end use. Combining long-lasting performance with a more sustainable profile, it is an excellent choice for creating modern, elegant musky accords across fine fragrance, personal care and home care formulations.

Technical standards

Physical appearance Solid Conform
Color Pale white to white Conform
Flash point ≥ 100.0°C Conform
Purity ≥ 98.5% 99.1%

Solubility @25˚C

Solvent Solubility (g/L)
ethanol 716.89
methanol 569.57
isopropanol 859.24
water 0.04
ethyl acetate 2110.54
n-propanol 803.09
acetone 2320.38
n-butanol 786.42
acetonitrile 1236.11
DMF 2589.85
toluene 1271.15
isobutanol 699.67
1,4-dioxane 2010.08
methyl acetate 1300.06
THF 3904.33
2-butanone 1826.42
n-pentanol 527.88
sec-butanol 775.97
n-hexane 446.96
ethylene glycol 67.51
NMP 2541.53
cyclohexane 1002.92
DMSO 2369.22
n-butyl acetate 1765.59
n-octanol 402.98
chloroform 5841.18
n-propyl acetate 1590.59
acetic acid 1000.39
dichloromethane 5358.84
cyclohexanone 3825.02
propylene glycol 182.16
isopropyl acetate 1605.87
DMAc 1816.54
2-ethoxyethanol 707.89
isopentanol 834.22
n-heptane 298.3
ethyl formate 1007.22
1,2-dichloroethane 3456.56
n-hexanol 598.38
2-methoxyethanol 1105.07
isobutyl acetate 1021.05
tetrachloromethane 980.5
n-pentyl acetate 1525.12
transcutol 3321.47
n-heptanol 364.81
ethylbenzene 643.71
MIBK 1258.72
2-propoxyethanol 923.36
tert-butanol 1087.74
MTBE 1448.67
2-butoxyethanol 776.76
propionic acid 948.11
o-xylene 722.09
formic acid 163.5
diethyl ether 1689.22
m-xylene 764.91
p-xylene 859.04
chlorobenzene 1929.31
dimethyl carbonate 540.84
n-octane 107.62
formamide 369.6
cyclopentanone 3935.21
2-pentanone 1982.07
anisole 1052.41
cyclopentyl methyl ether 2197.58
gamma-butyrolactone 3763.82
1-methoxy-2-propanol 1078.71
pyridine 3146.05
3-pentanone 1468.67
furfural 2741.52
n-dodecane 63.6
diethylene glycol 430.21
diisopropyl ether 675.83
tert-amyl alcohol 913.35
acetylacetone 2166.38
n-hexadecane 78.54
acetophenone 1103.14
methyl propionate 1359.08
isopentyl acetate 1457.68
trichloroethylene 5775.22
n-nonanol 372.45
cyclohexanol 1371.88
benzyl alcohol 695.93
2-ethylhexanol 539.12
isooctanol 373.69
dipropyl ether 1233.28
1,2-dichlorobenzene 1782.07
ethyl lactate 464.99
propylene carbonate 2092.58
n-methylformamide 999.21
2-pentanol 737.54
n-pentane 313.61
1-propoxy-2-propanol 942.84
1-methoxy-2-propyl acetate 1264.08
2-(2-methoxypropoxy) propanol 668.74
mesitylene 538.63
ε-caprolactone 2778.27
p-cymene 406.23
epichlorohydrin 3424.49
1,1,1-trichloroethane 3395.42
2-aminoethanol 244.34
morpholine-4-carbaldehyde 2113.41
sulfolane 4163.68
2,2,4-trimethylpentane 133.89
2-methyltetrahydrofuran 2747.93
n-hexyl acetate 1536.28
isooctane 116.65
2-(2-butoxyethoxy)ethanol 1040.35
sec-butyl acetate 1120.19
tert-butyl acetate 1541.74
decalin 319.33
glycerin 254.51
diglyme 2116.69
acrylic acid 737.49
isopropyl myristate 533.82
n-butyric acid 1850.95
acetyl acetate 1325.47
di(2-ethylhexyl) phthalate 377.15
ethyl propionate 1344.22
nitromethane 2059.47
1,2-diethoxyethane 1630.68
benzonitrile 1357.73
trioctyl phosphate 290.27
1-bromopropane 2146.83
gamma-valerolactone 3781.54
n-decanol 255.0
triethyl phosphate 528.3
4-methyl-2-pentanol 470.14
propionitrile 1309.23
vinylene carbonate 1711.87
1,1,2-trichlorotrifluoroethane 2044.64
DMS 984.5
cumene 412.45
2-octanol 342.7
2-hexanone 1350.98
octyl acetate 629.24
limonene 685.74
1,2-dimethoxyethane 1773.15
ethyl orthosilicate 496.53
tributyl phosphate 425.92
diacetone alcohol 1142.22
N,N-dimethylaniline 665.4
acrylonitrile 1546.43
aniline 1225.81
1,3-propanediol 504.0
bromobenzene 2423.16
dibromomethane 3679.37
1,1,2,2-tetrachloroethane 4943.96
2-methyl-cyclohexyl acetate 885.54
tetrabutyl urea 538.57
diisobutyl methanol 404.13
2-phenylethanol 595.4
styrene 921.73
dioctyl adipate 767.37
dimethyl sulfate 924.03
ethyl butyrate 1315.51
methyl lactate 522.49
butyl lactate 807.15
diethyl carbonate 785.86
propanediol butyl ether 639.09
triethyl orthoformate 871.87
p-tert-butyltoluene 383.63
methyl 4-tert-butylbenzoate 901.86
morpholine 2470.33
tert-butylamine 803.04
n-dodecanol 193.65
dimethoxymethane 1318.78
ethylene carbonate 1623.54
cyrene 588.06
2-ethoxyethyl acetate 1421.77
2-ethylhexyl acetate 1204.65
1,2,4-trichlorobenzene 1896.95
4-methylpyridine 2649.45
dibutyl ether 1170.93
2,6-dimethyl-4-heptanol 404.13
DEF 2159.33
dimethyl isosorbide 1263.53
tetrachloroethylene 3239.99
eugenol 667.94
triacetin 1249.86
span 80 753.39
1,4-butanediol 185.81
1,1-dichloroethane 3424.64
2-methyl-1-pentanol 529.9
methyl formate 684.24
2-methyl-1-butanol 724.92
n-decane 130.47
butyronitrile 1529.47
3,7-dimethyl-1-octanol 478.47
1-chlorooctane 544.69
1-chlorotetradecane 189.55
n-nonane 138.95
undecane 85.37
tert-butylcyclohexane 237.73
cyclooctane 296.52
cyclopentanol 1371.61
tetrahydropyran 3004.44
tert-amyl methyl ether 1092.19
2,5,8-trioxanonane 1212.17
1-hexene 986.41
2-isopropoxyethanol 624.72
2,2,2-trifluoroethanol 374.51
methyl butyrate 1869.47

Scent© AI

View full details

  • CAS NO.

    106-02-5

  • OLFACTIVE FAMILY

    Musky

  • BRAND

    Symrise

Olfactory Pyramid

base

Notes

Musk
Sweet
Animal
Powdery
Waxy

IFRA standard 51

Recommendation
Restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 0.42 % Category 7A
Rinse-off products applied to the hair with some hand contact
 4.8 %
Category 2
Products applied to the axillae
 0.13 % Category 7B
Leave-on products applied to the hair with some hand contact
 4.8 %
Category 3
Products applied to the face/body using fingertips
 2.5 % Category 8
Products with significant anogenital exposure
 0.2 %
Category 4
Products related to fine fragrance
 2.4 % Category 9
Products with body and hand exposure, primarily rinse off
 4.6 %
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 0.6 % Category 10A
Household care products with mostly hand contact
 4.6 %
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 0.6 % Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 17 %
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 0.6 % Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 0.2 %
Category 5D
Baby Creams, baby Oils and baby talc
 0.2 % Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 0.2 %
Category 6
Products with oral and lip exposure
 1.4 % Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Shipping & Returns

  • All orders will be processed within 1-2 business days from the time the order is confirmed.
  • Free shipping is available for orders valued at $200 or more.
  • Delivery time is 1-3 business days for local areas, 3-7 days for suburban and nationwide deliveries, and 1-4 weeks for international orders.
  • You have 30 days from the date of receipt to initiate the return process.
1 4

Certificates of Quality

  • Certificate of Analysis (COA)

    Provides information on the physical and chemical properties of the product.
    Download  

  • IFRA Certificate of Conformity

    Sets safety standards and guidelines for the product in manufacturing.
    Download  

  • Safety Data Sheet (SDS)

    Provides important safety guidelines for transporting, storing, and using the product.
    Download  
1 3