Kephalis aka. Woody Cyclohexanone Aroma Chemical
CAS# 36306-87-3
Woody, Herbal, Camphoreous, Tobacco, Mint
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Kephalis is highly regarded in fragrance compounding thanks to its warm woody and ambery character, along with its flexible and effective blending performance. Its trade name-and also the name most commonly used for it-is Kephalis.
In terms of origin, this is a fully synthetic compound that does not occur naturally. It was created and patented by the fragrance company Givaudan. Introduced in the 1990s, Kephalis provided perfumers with a new and efficient tool to build modern woody and ambergris-like effects without relying entirely on traditional raw materials.
In appearance, Kephalis is a clear liquid, colorless to pale yellow. Its scent is described as a fusion of woody and ambery notes, accented by spicy and tobacco-like facets. Thanks to this complex olfactory profile, it is widely used in perfumery-especially in men’s and unisex fragrances-where it adds warmth, depth, and richness to woody, oriental, and tobacco accords.
Description
From an olfactory standpoint, Kephalis is classified in the Woody and Ambery family. In a fragrance formula, it functions as a heart and base note, acting as a modifier and as an important building block for the drydown.
Kephalis has a rich, multi-faceted scent profile. It opens with a warm woody tone and an ambery nuance, then gradually develops a mild spicy facet reminiscent of cardamom, along with a touch of dry tobacco, creating a smooth and deep overall impression. Its odor intensity is medium, with good diffusion and strong substantivity, lasting around 100 hours on a blotter.
In application, Kephalis is a key material for constructing modern woody and ambergris-style accords. It blends well with a wide range of ingredients-from florals and spices to other woods-enhancing warmth, richness, and structure in the heart and base, and producing a smooth, attractive effect. Kephalis is often paired with other woody molecules such as Iso E Super to create a complex, radiating woody effect, and it also performs very well alongside rose and spicy notes. Technically, because it is a liquid and readily soluble in alcohol and common solvents, Kephalis can be used directly in formulas without pre-dilution.
Applications
Kephalis is mainly used in fine fragrance, but its versatility also allows it to be used in personal care products such as shower gels and deodorants, as well as home care products such as scented candles, room sprays, and cleaning products, to deliver a warm, long-lasting woody scent.
From a regulatory perspective, under IFRA standards, Kephalis is not restricted in terms of use level. In practice, its concentration in fragrance concentrates typically ranges from 1% to 10%. In terms of safety, Kephalis is considered a mild ingredient and is not on the EU list of allergens that require labeling. It also has no special storage requirements.
Kephalis is a favored ingredient in many modern fragrances, especially men’s fragrances. Notable examples include Gucci Pour Homme II by Gucci, AMen* by Mugler, and L’Instant de Guerlain pour Homme by Guerlain.
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Technical standards
Technical standards
| Physical appearance | Transparent liquid | Conform |
| Color | Clear to pale yellow | Conform |
| Specific Gravity @20˚C | 0.942 → 0.952 | 0.9466 |
| Refractive Index @20˚C | 1.472 → 1.478 | 1.4757 |
Solubility @25˚C
Solubility @25˚C
| Solvent | Solubility (g/L) |
|---|---|
| ethanol | 1074.51 |
| methanol | 1485.92 |
| isopropanol | 990.39 |
| water | 12.43 |
| ethyl acetate | 1520.35 |
| n-propanol | 1078.94 |
| acetone | 1614.87 |
| n-butanol | 921.59 |
| acetonitrile | 1647.76 |
| DMF | 1787.53 |
| toluene | 1785.68 |
| isobutanol | 932.23 |
| 1,4-dioxane | 2153.33 |
| methyl acetate | 1465.48 |
| THF | 4200.89 |
| 2-butanone | 1252.33 |
| n-pentanol | 607.08 |
| sec-butanol | 956.53 |
| n-hexane | 458.17 |
| ethylene glycol | 255.08 |
| NMP | 2708.26 |
| cyclohexane | 1115.01 |
| DMSO | 841.04 |
| n-butyl acetate | 1051.73 |
| n-octanol | 564.45 |
| chloroform | 5107.18 |
| n-propyl acetate | 795.37 |
| acetic acid | 1786.28 |
| dichloromethane | 3598.2 |
| cyclohexanone | 2938.95 |
| propylene glycol | 389.57 |
| isopropyl acetate | 954.4 |
| DMAc | 1454.25 |
| 2-ethoxyethanol | 489.91 |
| isopentanol | 733.82 |
| n-heptane | 442.56 |
| ethyl formate | 1116.58 |
| 1,2-dichloroethane | 1814.25 |
| n-hexanol | 1289.58 |
| 2-methoxyethanol | 949.9 |
| isobutyl acetate | 556.78 |
| tetrachloromethane | 1183.39 |
| n-pentyl acetate | 732.18 |
| transcutol | 1035.8 |
| n-heptanol | 496.45 |
| ethylbenzene | 713.22 |
| MIBK | 774.03 |
| 2-propoxyethanol | 1095.53 |
| tert-butanol | 1092.14 |
| MTBE | 1035.62 |
| 2-butoxyethanol | 482.47 |
| propionic acid | 1261.44 |
| o-xylene | 970.48 |
| formic acid | 657.95 |
| diethyl ether | 1175.85 |
| m-xylene | 1219.92 |
| p-xylene | 956.75 |
| chlorobenzene | 1851.5 |
| dimethyl carbonate | 662.58 |
| n-octane | 140.28 |
| formamide | 556.87 |
| cyclopentanone | 2925.94 |
| 2-pentanone | 1229.6 |
| anisole | 786.59 |
| cyclopentyl methyl ether | 2378.99 |
| gamma-butyrolactone | 3581.14 |
| 1-methoxy-2-propanol | 814.67 |
| pyridine | 2159.74 |
| 3-pentanone | 1019.08 |
| furfural | 2074.43 |
| n-dodecane | 85.27 |
| diethylene glycol | 596.52 |
| diisopropyl ether | 495.68 |
| tert-amyl alcohol | 942.67 |
| acetylacetone | 1272.41 |
| n-hexadecane | 100.24 |
| acetophenone | 735.27 |
| methyl propionate | 1282.9 |
| isopentyl acetate | 836.49 |
| trichloroethylene | 3771.43 |
| n-nonanol | 450.16 |
| cyclohexanol | 1870.74 |
| benzyl alcohol | 729.74 |
| 2-ethylhexanol | 719.43 |
| isooctanol | 371.16 |
| dipropyl ether | 750.53 |
| 1,2-dichlorobenzene | 1357.04 |
| ethyl lactate | 372.17 |
| propylene carbonate | 1989.21 |
| n-methylformamide | 1185.3 |
| 2-pentanol | 768.67 |
| n-pentane | 483.31 |
| 1-propoxy-2-propanol | 756.04 |
| 1-methoxy-2-propyl acetate | 946.6 |
| 2-(2-methoxypropoxy) propanol | 423.41 |
| mesitylene | 751.63 |
| ε-caprolactone | 2370.2 |
| p-cymene | 472.93 |
| epichlorohydrin | 2695.0 |
| 1,1,1-trichloroethane | 2632.44 |
| 2-aminoethanol | 455.0 |
| morpholine-4-carbaldehyde | 1651.72 |
| sulfolane | 2402.37 |
| 2,2,4-trimethylpentane | 197.19 |
| 2-methyltetrahydrofuran | 3041.1 |
| n-hexyl acetate | 1154.11 |
| isooctane | 145.42 |
| 2-(2-butoxyethoxy)ethanol | 503.54 |
| sec-butyl acetate | 556.12 |
| tert-butyl acetate | 888.93 |
| decalin | 346.52 |
| glycerin | 427.87 |
| diglyme | 893.17 |
| acrylic acid | 1111.11 |
| isopropyl myristate | 340.85 |
| n-butyric acid | 1571.56 |
| acetyl acetate | 1174.32 |
| di(2-ethylhexyl) phthalate | 329.91 |
| ethyl propionate | 767.25 |
| nitromethane | 2152.93 |
| 1,2-diethoxyethane | 558.65 |
| benzonitrile | 1209.25 |
| trioctyl phosphate | 262.62 |
| 1-bromopropane | 1463.68 |
| gamma-valerolactone | 2727.13 |
| n-decanol | 310.45 |
| triethyl phosphate | 344.13 |
| 4-methyl-2-pentanol | 448.28 |
| propionitrile | 1219.4 |
| vinylene carbonate | 1828.41 |
| 1,1,2-trichlorotrifluoroethane | 1499.12 |
| DMS | 868.3 |
| cumene | 464.01 |
| 2-octanol | 441.03 |
| 2-hexanone | 759.12 |
| octyl acetate | 461.55 |
| limonene | 748.32 |
| 1,2-dimethoxyethane | 919.49 |
| ethyl orthosilicate | 325.01 |
| tributyl phosphate | 311.7 |
| diacetone alcohol | 716.65 |
| N,N-dimethylaniline | 533.3 |
| acrylonitrile | 1387.41 |
| aniline | 1311.33 |
| 1,3-propanediol | 601.1 |
| bromobenzene | 1960.75 |
| dibromomethane | 2678.09 |
| 1,1,2,2-tetrachloroethane | 2840.4 |
| 2-methyl-cyclohexyl acetate | 604.95 |
| tetrabutyl urea | 368.42 |
| diisobutyl methanol | 319.01 |
| 2-phenylethanol | 825.8 |
| styrene | 802.2 |
| dioctyl adipate | 446.58 |
| dimethyl sulfate | 854.47 |
| ethyl butyrate | 670.85 |
| methyl lactate | 540.48 |
| butyl lactate | 515.31 |
| diethyl carbonate | 479.61 |
| propanediol butyl ether | 492.28 |
| triethyl orthoformate | 464.0 |
| p-tert-butyltoluene | 467.1 |
| methyl 4-tert-butylbenzoate | 663.9 |
| morpholine | 2340.77 |
| tert-butylamine | 886.68 |
| n-dodecanol | 223.43 |
| dimethoxymethane | 1218.83 |
| ethylene carbonate | 1602.42 |
| cyrene | 554.29 |
| 2-ethoxyethyl acetate | 730.87 |
| 2-ethylhexyl acetate | 757.2 |
| 1,2,4-trichlorobenzene | 1474.82 |
| 4-methylpyridine | 2448.86 |
| dibutyl ether | 527.34 |
| 2,6-dimethyl-4-heptanol | 319.01 |
| DEF | 1171.7 |
| dimethyl isosorbide | 905.67 |
| tetrachloroethylene | 2051.45 |
| eugenol | 502.2 |
| triacetin | 786.54 |
| span 80 | 494.81 |
| 1,4-butanediol | 256.28 |
| 1,1-dichloroethane | 2331.32 |
| 2-methyl-1-pentanol | 510.01 |
| methyl formate | 1222.69 |
| 2-methyl-1-butanol | 794.9 |
| n-decane | 173.63 |
| butyronitrile | 1304.97 |
| 3,7-dimethyl-1-octanol | 458.23 |
| 1-chlorooctane | 535.31 |
| 1-chlorotetradecane | 174.65 |
| n-nonane | 196.59 |
| undecane | 117.75 |
| tert-butylcyclohexane | 271.93 |
| cyclooctane | 418.9 |
| cyclopentanol | 1841.18 |
| tetrahydropyran | 3030.54 |
| tert-amyl methyl ether | 853.24 |
| 2,5,8-trioxanonane | 596.98 |
| 1-hexene | 832.63 |
| 2-isopropoxyethanol | 387.16 |
| 2,2,2-trifluoroethanol | 734.89 |
| methyl butyrate | 979.21 |
Scent© AI

Olfactory Pyramid
Notes
| Woody |
| Herbal |
| Camphoreous |
| Tobacco |
| Mint |
| Maximum acceptable concentrations in the finished product (%) | |||
|---|---|---|---|
|
Category 1
Products applied to the lips
|
No restriction |
Category 7A
Rinse-off products applied to the hair with some hand contact
|
No restriction |
|
Category 2
Products applied to the axillae
|
No restriction |
Category 7B
Leave-on products applied to the hair with some hand contact
|
No restriction |
|
Category 3
Products applied to the face/body using fingertips
|
No restriction |
Category 8
Products with significant anogenital exposure
|
No restriction |
|
Category 4
Products related to fine fragrance
|
No restriction |
Category 9
Products with body and hand exposure, primarily rinse off
|
No restriction |
|
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
|
No restriction |
Category 10A
Household care products with mostly hand contact
|
No restriction |
|
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
|
No restriction |
Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
|
No restriction |
|
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
|
No restriction |
Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
|
No restriction |
|
Category 5D
Baby Creams, baby Oils and baby talc
|
No restriction |
Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
|
No restriction |
|
Category 6
Products with oral and lip exposure
|
No restriction |
Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
|
No restriction |
Shipping & Returns
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Delivery time is 1-3 business days for local areas, 3-7 days for suburban and nationwide deliveries, and 1-4 weeks for international orders. -
You have 30 days from the date of receipt to initiate the return process.
Certificates of Quality
-
Certificate of Analysis (COA)
Provides information on the physical and chemical properties of the product.Download -
IFRA Certificate of Conformity
Sets safety standards and guidelines for the product in manufacturing.Download -
Safety Data Sheet (SDS)
Provides important safety guidelines for transporting, storing, and using the product.Download