Iso Eugenol Aroma Chemical
CAS# 97-54-1 / 5932-68-3
Spicy, Sweet, Clove, Phenolic, Woody
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Isoeugenol is a nature-identical and synthetic material with a historic role in the fragrance industry. Although it occurs in small amounts in ylang ylang, nutmeg, and clove essential oils, it is produced industrially mainly through the isomerization of Eugenol. In the late 19th century, Isoeugenol was an extremely important intermediate in the first synthetic Vanillin production process, marking a major advance in industrial chemistry. Physically, it is a slightly viscous liquid ranging from clear to pale yellow, and it tends to darken upon exposure to air.
Description
Belonging to the spicy-floral family, Isoeugenol gives off a warm, sweet, and rich scent, characterized by a carnation note intertwined with subtle woody and vanilla nuances. Functioning from the middle note to the base note, and serving as a fixative, blender, and modifier, this material has strong odor impact, good diffusion, and a lasting tenacity of hundreds of hours on a blotter. In fragrance formulas, it helps build carnation notes, supports oriental accords, and links floral components with spices. Perfumers often pair it with Eugenol, Benzyl Salicylate, Ylang Ylang, and Linalool to create the classic carnation accord. Because of its very strong odor and slight viscosity, it is often diluted in DPG for easier control.
Applications
In terms of applications, this material is used in perfumes, scented candles, leave-on cosmetics, rinse-off products, soap, and food flavorings. However, Isoeugenol is very strictly controlled by IFRA due to its high skin sensitization potential, with recommended usage levels often limited to below 0.02% to 0.2% depending on the product category. Users should note in particular that it is a mandatory declarable allergen in Europe and can easily discolor soap to brown or dark yellow in alkaline conditions. Proper storage requires keeping the container tightly closed, in a cool, dry place, away from direct light. Many perfume masterpieces, such as Bellodgia by Caron and L’Air du Temps by Nina Ricci, bear the distinct signature of this ingredient. Finally, the value of this material was affirmed in Perfume and Flavor Chemicals, where expert Steffen Arctander described Isoeugenol as having a sweet, warm spicy-floral odor characteristic of carnation. He noted that it is softer and more floral than Eugenol, making it an essential material in carnation accords, while also carefully warning about its tendency to discolor when exposed to alkali or light.
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Technical standards
Technical standards
Solubility @25˚C
Solubility @25˚C
| Solvent | Solubility (g/L) |
|---|---|
| ethanol | 1294.94 |
| methanol | 1411.37 |
| isopropanol | 904.23 |
| water | 1.08 |
| ethyl acetate | 1562.66 |
| n-propanol | 1152.57 |
| acetone | 2257.19 |
| n-butanol | 799.05 |
| acetonitrile | 1890.28 |
| DMF | 1846.13 |
| toluene | 331.34 |
| isobutanol | 681.1 |
| 1,4-dioxane | 1982.92 |
| methyl acetate | 1486.87 |
| THF | 2120.88 |
| 2-butanone | 1380.19 |
| n-pentanol | 454.96 |
| sec-butanol | 763.93 |
| n-hexane | 66.5 |
| ethylene glycol | 353.32 |
| NMP | 954.96 |
| cyclohexane | 136.18 |
| DMSO | 2671.34 |
| n-butyl acetate | 651.61 |
| n-octanol | 170.84 |
| chloroform | 1789.09 |
| n-propyl acetate | 694.14 |
| acetic acid | 1135.24 |
| dichloromethane | 2073.57 |
| cyclohexanone | 1240.23 |
| propylene glycol | 368.96 |
| isopropyl acetate | 542.94 |
| DMAc | 728.79 |
| 2-ethoxyethanol | 900.89 |
| isopentanol | 584.82 |
| n-heptane | 37.38 |
| ethyl formate | 766.94 |
| 1,2-dichloroethane | 1813.96 |
| n-hexanol | 455.1 |
| 2-methoxyethanol | 1681.33 |
| isobutyl acetate | 319.28 |
| tetrachloromethane | 282.61 |
| n-pentyl acetate | 261.54 |
| transcutol | 1964.88 |
| n-heptanol | 166.9 |
| ethylbenzene | 166.41 |
| MIBK | 459.67 |
| 2-propoxyethanol | 743.53 |
| tert-butanol | 1299.55 |
| MTBE | 1147.3 |
| 2-butoxyethanol | 334.98 |
| propionic acid | 877.71 |
| o-xylene | 171.7 |
| formic acid | 421.2 |
| diethyl ether | 1651.68 |
| m-xylene | 200.89 |
| p-xylene | 179.75 |
| chlorobenzene | 536.2 |
| dimethyl carbonate | 490.45 |
| n-octane | 17.13 |
| formamide | 1064.97 |
| cyclopentanone | 1682.22 |
| 2-pentanone | 1073.23 |
| anisole | 470.05 |
| cyclopentyl methyl ether | 823.8 |
| gamma-butyrolactone | 1919.7 |
| 1-methoxy-2-propanol | 934.06 |
| pyridine | 1135.32 |
| 3-pentanone | 780.87 |
| furfural | 1134.29 |
| n-dodecane | 14.34 |
| diethylene glycol | 624.89 |
| diisopropyl ether | 255.19 |
| tert-amyl alcohol | 884.28 |
| acetylacetone | 943.2 |
| n-hexadecane | 16.99 |
| acetophenone | 359.58 |
| methyl propionate | 1111.23 |
| isopentyl acetate | 454.16 |
| trichloroethylene | 2491.5 |
| n-nonanol | 144.66 |
| cyclohexanol | 581.05 |
| benzyl alcohol | 335.09 |
| 2-ethylhexanol | 219.76 |
| isooctanol | 135.02 |
| dipropyl ether | 294.64 |
| 1,2-dichlorobenzene | 406.45 |
| ethyl lactate | 221.22 |
| propylene carbonate | 755.7 |
| n-methylformamide | 1265.61 |
| 2-pentanol | 529.15 |
| n-pentane | 77.62 |
| 1-propoxy-2-propanol | 430.46 |
| 1-methoxy-2-propyl acetate | 452.51 |
| 2-(2-methoxypropoxy) propanol | 291.85 |
| mesitylene | 130.6 |
| ε-caprolactone | 947.91 |
| p-cymene | 92.03 |
| epichlorohydrin | 2226.91 |
| 1,1,1-trichloroethane | 1267.26 |
| 2-aminoethanol | 595.07 |
| morpholine-4-carbaldehyde | 988.26 |
| sulfolane | 1726.16 |
| 2,2,4-trimethylpentane | 44.01 |
| 2-methyltetrahydrofuran | 1402.04 |
| n-hexyl acetate | 366.92 |
| isooctane | 37.5 |
| 2-(2-butoxyethoxy)ethanol | 445.21 |
| sec-butyl acetate | 347.62 |
| tert-butyl acetate | 548.91 |
| decalin | 54.3 |
| glycerin | 473.69 |
| diglyme | 896.1 |
| acrylic acid | 742.17 |
| isopropyl myristate | 127.77 |
| n-butyric acid | 954.21 |
| acetyl acetate | 594.26 |
| di(2-ethylhexyl) phthalate | 107.33 |
| ethyl propionate | 527.27 |
| nitromethane | 2407.04 |
| 1,2-diethoxyethane | 613.32 |
| benzonitrile | 429.14 |
| trioctyl phosphate | 92.09 |
| 1-bromopropane | 849.1 |
| gamma-valerolactone | 1487.81 |
| n-decanol | 106.78 |
| triethyl phosphate | 146.74 |
| 4-methyl-2-pentanol | 236.23 |
| propionitrile | 1068.85 |
| vinylene carbonate | 691.6 |
| 1,1,2-trichlorotrifluoroethane | 1065.8 |
| DMS | 365.28 |
| cumene | 107.65 |
| 2-octanol | 115.73 |
| 2-hexanone | 563.62 |
| octyl acetate | 164.39 |
| limonene | 142.14 |
| 1,2-dimethoxyethane | 1212.26 |
| ethyl orthosilicate | 144.14 |
| tributyl phosphate | 120.24 |
| diacetone alcohol | 573.09 |
| N,N-dimethylaniline | 217.43 |
| acrylonitrile | 1249.44 |
| aniline | 554.54 |
| 1,3-propanediol | 806.98 |
| bromobenzene | 530.59 |
| dibromomethane | 1380.72 |
| 1,1,2,2-tetrachloroethane | 1733.06 |
| 2-methyl-cyclohexyl acetate | 222.58 |
| tetrabutyl urea | 139.56 |
| diisobutyl methanol | 127.42 |
| 2-phenylethanol | 277.15 |
| styrene | 247.29 |
| dioctyl adipate | 178.65 |
| dimethyl sulfate | 627.54 |
| ethyl butyrate | 356.21 |
| methyl lactate | 365.29 |
| butyl lactate | 191.78 |
| diethyl carbonate | 245.15 |
| propanediol butyl ether | 327.98 |
| triethyl orthoformate | 213.9 |
| p-tert-butyltoluene | 93.42 |
| methyl 4-tert-butylbenzoate | 229.2 |
| morpholine | 2103.25 |
| tert-butylamine | 677.3 |
| n-dodecanol | 80.84 |
| dimethoxymethane | 1281.2 |
| ethylene carbonate | 612.2 |
| cyrene | 284.41 |
| 2-ethoxyethyl acetate | 410.82 |
| 2-ethylhexyl acetate | 340.62 |
| 1,2,4-trichlorobenzene | 480.35 |
| 4-methylpyridine | 851.32 |
| dibutyl ether | 242.31 |
| 2,6-dimethyl-4-heptanol | 127.42 |
| DEF | 883.24 |
| dimethyl isosorbide | 452.32 |
| tetrachloroethylene | 1089.89 |
| eugenol | 241.96 |
| triacetin | 326.38 |
| span 80 | 227.51 |
| 1,4-butanediol | 278.64 |
| 1,1-dichloroethane | 1540.18 |
| 2-methyl-1-pentanol | 373.71 |
| methyl formate | 1066.77 |
| 2-methyl-1-butanol | 568.85 |
| n-decane | 23.67 |
| butyronitrile | 839.74 |
| 3,7-dimethyl-1-octanol | 163.5 |
| 1-chlorooctane | 122.44 |
| 1-chlorotetradecane | 46.09 |
| n-nonane | 23.88 |
| undecane | 17.88 |
| tert-butylcyclohexane | 50.04 |
| cyclooctane | 42.04 |
| cyclopentanol | 646.23 |
| tetrahydropyran | 1763.72 |
| tert-amyl methyl ether | 583.94 |
| 2,5,8-trioxanonane | 517.52 |
| 1-hexene | 252.11 |
| 2-isopropoxyethanol | 515.86 |
| 2,2,2-trifluoroethanol | 370.53 |
| methyl butyrate | 684.29 |
Scent© AI

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CAS NUMBER
97-54-1
5932-68-3 -
FAMILIES
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BRAND
Scent.vn
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EVAPORATION RATE
Slow
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Odor impact
High est.
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FLASH POINT
115.58 ˚C est.
Olfactory Pyramid
Notes
| Spicy |
| Sweet |
| Clove |
| Phenolic |
| Woody |
| Maximum acceptable concentrations in the finished product (%) | |||
|---|---|---|---|
|
Category 1
Products applied to the lips
|
0.019 % |
Category 7A
Rinse-off products applied to the hair with some hand contact
|
0.22 % |
|
Category 2
Products applied to the axillae
|
0.0057 % |
Category 7B
Leave-on products applied to the hair with some hand contact
|
0.22 % |
|
Category 3
Products applied to the face/body using fingertips
|
0.12 % |
Category 8
Products with significant anogenital exposure
|
0.009 % |
|
Category 4
Products related to fine fragrance
|
0.11 % |
Category 9
Products with body and hand exposure, primarily rinse off
|
0.21 % |
|
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
|
0.027 % |
Category 10A
Household care products with mostly hand contact
|
0.21 % |
|
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
|
0.027 % |
Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
|
0.75 % |
|
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
|
0.027 % |
Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
|
0.009 % |
|
Category 5D
Baby Creams, baby Oils and baby talc
|
0.009 % |
Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
|
0.009 % |
|
Category 6
Products with oral and lip exposure
|
0.063 % |
Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
|
No restriction |
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Certificates of Quality
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Certificate of Analysis (COA)
Provides information on the physical and chemical properties of the product.Download -
IFRA Certificate of Conformity
Sets safety standards and guidelines for the product in manufacturing.Download -
Safety Data Sheet (SDS)
Provides important safety guidelines for transporting, storing, and using the product.Download