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Tripropylene Glycol Methyl Ether TPM Solvent
CAS# 25498-49-1

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Tripropylene Glycol Monomethyl Ether (TPM), also widely known by trade names such as Glycol Ether TPM or DOWANOL™ TPM, is a versatile, hydrophilic solvent characterized by its low volatility and extremely slow evaporation rate. It is a clear, colorless liquid with a mild, ether-like odor that is completely miscible in water. Notably, TPM has a high boiling point of approximately 242.8°C (469°F) and an exceptionally low vapor pressure of less than 0.1 mmHg at 25°C.

Physicochemically, TPM demonstrates excellent solvency for both polar and non-polar substances. Thanks to a unique molecular architecture with a hydrophilic-lipophilic balance that bridges the gap between aqueous and organic phases, it functions as a highly effective coupling agent and coalescent. Furthermore, its low surface tension of 29 dynes/cm at 25°C (77°F) enhances its wetting capabilities. From an environmental standpoint, TPM is readily biodegradable and, due to its very low vapor pressure, may not be considered a Volatile Organic Compound (VOC) under certain circumstances of use.

In the industrial sector, TPM plays a core role in the manufacturing of coatings, inks, and cleaning agents. For paints and coatings, particularly water-based systems, TPM acts as a premium coalescing agent that helps polymer particles merge during drying to create a uniform, durable film while moderating the overall evaporation rate. In the ink industry, its slow evaporation rate makes it ideal for ballpoint pens, felt-tip pens, and stamp pads, preventing the ink from drying out prematurely and maintaining rheological properties over time. For cleaning products, TPM is highly effective in oven cleaners, wax strippers, and large-area floor cleaners because it provides strong solvation for greases and oils while producing an exceptionally low amount of undesirable solvent vapor in enclosed areas.

Another breakthrough application for TPM is in the SLA 3D printing industry. TPM is utilized as a wash solvent to dissolve and clean uncured liquid resin from stereolithography (SLA) 3D printed parts, serving as a highly effective alternative to Isopropyl Alcohol (IPA). Compared to IPA, TPM is non-flammable, has a significantly lower odor, and can wash about three times as many printed parts before becoming saturated and needing to be replaced.

Regarding health and safety, TPM exhibits very low acute toxicity across all routes of exposure (oral, dermal, and inhalation) and is not classified as hazardous under the Globally Harmonized System (GHS). With a high flash point ranging from 111°C to 124°C, it is considered non-flammable under normal conditions, which significantly mitigates the risk of fire and explosion hazards in the workplace, making it much safer to store and handle.

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Technical standards

Physical appearance Transparent liquid Conform
Color Colorless Conform
Specific Gravity @20˚C 0.962 → 0.967 0.965
Acid value (% Acetic acid) ≤ 0.01 0.007
Water content ≤ 0.1% 0.013%
Purity ≥ 97.5% 99.3%

Solubility @25˚C

Solvent Solubility (g/L)
ethanol 455.37
methanol 791.94
isopropanol 294.08
water 39.02
ethyl acetate 143.6
n-propanol 327.8
acetone 163.17
n-butanol 244.43
acetonitrile 170.75
DMF 328.15
toluene 38.61
isobutanol 204.52
1,4-dioxane 398.71
methyl acetate 162.96
THF 390.85
2-butanone 132.4
n-pentanol 145.62
sec-butanol 249.72
n-hexane 11.21
ethylene glycol 237.69
NMP 294.56
cyclohexane 49.77
DMSO 710.14
n-butyl acetate 85.75
n-octanol 66.67
chloroform 542.37
n-propyl acetate 91.4
acetic acid 851.36
dichloromethane 536.14
cyclohexanone 284.44
propylene glycol 275.28
isopropyl acetate 69.18
DMAc 329.1
2-ethoxyethanol 375.04
isopentanol 152.42
n-heptane 15.45
ethyl formate 166.28
1,2-dichloroethane 248.47
n-hexanol 119.23
2-methoxyethanol 581.37
isobutyl acetate 59.33
tetrachloromethane 93.37
n-pentyl acetate 62.2
transcutol 536.92
n-heptanol 63.24
ethylbenzene 29.09
MIBK 48.14
2-propoxyethanol 215.18
tert-butanol 331.0
MTBE 130.93
2-butoxyethanol 136.52
propionic acid 379.44
o-xylene 51.33
formic acid 521.05
diethyl ether 102.27
m-xylene 32.0
p-xylene 47.28
chlorobenzene 83.84
dimethyl carbonate 43.95
n-octane 7.09
formamide 412.55
cyclopentanone 257.09
2-pentanone 77.0
anisole 75.77
cyclopentyl methyl ether 143.92
gamma-butyrolactone 342.89
1-methoxy-2-propanol 306.08
pyridine 209.6
3-pentanone 74.19
furfural 378.09
n-dodecane 6.06
diethylene glycol 262.2
diisopropyl ether 25.5
tert-amyl alcohol 264.78
acetylacetone 113.39
n-hexadecane 6.68
acetophenone 97.61
methyl propionate 107.78
isopentyl acetate 80.72
trichloroethylene 477.19
n-nonanol 59.49
cyclohexanol 280.22
benzyl alcohol 115.54
2-ethylhexanol 71.62
isooctanol 51.79
dipropyl ether 61.68
1,2-dichlorobenzene 100.36
ethyl lactate 93.64
propylene carbonate 197.78
n-methylformamide 248.44
2-pentanol 119.58
n-pentane 13.47
1-propoxy-2-propanol 150.26
1-methoxy-2-propyl acetate 91.19
2-(2-methoxypropoxy) propanol 143.93
mesitylene 25.32
ε-caprolactone 275.5
p-cymene 33.48
epichlorohydrin 341.54
1,1,1-trichloroethane 186.21
2-aminoethanol 340.56
morpholine-4-carbaldehyde 372.99
sulfolane 470.54
2,2,4-trimethylpentane 12.94
2-methyltetrahydrofuran 273.01
n-hexyl acetate 93.39
isooctane 5.96
2-(2-butoxyethoxy)ethanol 177.84
sec-butyl acetate 58.1
tert-butyl acetate 73.81
decalin 17.79
glycerin 378.36
diglyme 347.05
acrylic acid 331.97
isopropyl myristate 37.96
n-butyric acid 347.69
acetyl acetate 121.45
di(2-ethylhexyl) phthalate 54.59
ethyl propionate 73.09
nitromethane 586.07
1,2-diethoxyethane 114.26
benzonitrile 118.53
trioctyl phosphate 40.24
1-bromopropane 113.95
gamma-valerolactone 392.87
n-decanol 42.34
triethyl phosphate 68.07
4-methyl-2-pentanol 54.48
propionitrile 139.06
vinylene carbonate 209.51
1,1,2-trichlorotrifluoroethane 488.69
DMS 79.36
cumene 27.5
2-octanol 41.11
2-hexanone 72.65
octyl acetate 52.68
limonene 54.03
1,2-dimethoxyethane 381.29
ethyl orthosilicate 62.6
tributyl phosphate 51.43
diacetone alcohol 122.52
N,N-dimethylaniline 66.94
acrylonitrile 178.1
aniline 117.16
1,3-propanediol 419.31
bromobenzene 72.83
dibromomethane 314.33
1,1,2,2-tetrachloroethane 411.8
2-methyl-cyclohexyl acetate 88.51
tetrabutyl urea 61.46
diisobutyl methanol 41.25
2-phenylethanol 84.62
styrene 35.55
dioctyl adipate 80.4
dimethyl sulfate 111.15
ethyl butyrate 81.71
methyl lactate 115.78
butyl lactate 87.79
diethyl carbonate 68.31
propanediol butyl ether 147.73
triethyl orthoformate 82.09
p-tert-butyltoluene 31.43
methyl 4-tert-butylbenzoate 100.29
morpholine 478.69
tert-butylamine 176.45
n-dodecanol 33.64
dimethoxymethane 134.37
ethylene carbonate 178.11
cyrene 152.32
2-ethoxyethyl acetate 88.79
2-ethylhexyl acetate 65.08
1,2,4-trichlorobenzene 130.76
4-methylpyridine 155.99
dibutyl ether 60.5
2,6-dimethyl-4-heptanol 41.25
DEF 156.7
dimethyl isosorbide 191.0
tetrachloroethylene 331.81
eugenol 105.08
triacetin 138.29
span 80 135.27
1,4-butanediol 184.38
1,1-dichloroethane 198.75
2-methyl-1-pentanol 111.31
methyl formate 187.57
2-methyl-1-butanol 170.57
n-decane 10.22
butyronitrile 129.34
3,7-dimethyl-1-octanol 64.14
1-chlorooctane 35.99
1-chlorotetradecane 15.27
n-nonane 10.0
undecane 7.37
tert-butylcyclohexane 14.4
cyclooctane 14.82
cyclopentanol 278.67
tetrahydropyran 308.64
tert-amyl methyl ether 100.36
2,5,8-trioxanonane 244.81
1-hexene 33.03
2-isopropoxyethanol 191.69
2,2,2-trifluoroethanol 327.33
methyl butyrate 122.82

Scent© AI

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  • CAS NUMBER

    25498-49-1

  • FAMILIES

    Solvent

  • BRAND

    Scent.vn

  • EVAPORATION RATE

    Slow

  • Odor impact

    Medium est.

  • FLASH POINT

    107.03 ˚C est.

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Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
No restriction
Category 2
Products applied to the axillae
No restriction Category 7B
Leave-on products applied to the hair with some hand contact
No restriction
Category 3
Products applied to the face/body using fingertips
No restriction Category 8
Products with significant anogenital exposure
No restriction
Category 4
Products related to fine fragrance
No restriction Category 9
Products with body and hand exposure, primarily rinse off
No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
No restriction Category 10A
Household care products with mostly hand contact
No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
No restriction
Category 5D
Baby Creams, baby Oils and baby talc
No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
No restriction
Category 6
Products with oral and lip exposure
No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
No restriction
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  • You have 30 days from the date of receipt to initiate the return process.
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  • Certificate of Analysis (COA)

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  • IFRA Certificate of Conformity

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  • Safety Data Sheet (SDS)

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