Tyrosol

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    501-94-0

    Molecular formula
    C8H10O2

    SMILES
    C1=CC(=CC=C1CCO)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Floral 78.81%
    Sweet 75.43%
    Fruity 66.81%
    Rose 59.92%
    Phenolic 52.83%
    Balsamic 43.23%
    Honey 40.84%
    Powdery 33.85%
    Almond 33.69%
    Animal 33.45%

    Scent© AI

  • Properties

    XLogP3-AA
    0.4

    pKa est.
    9.02 (weak base)

    Molecular weight
    138.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 90 °C

    Boiling point

    • 308.00 to 311.00 °C. @ 760.00 mm Hg

    Flash point est.
    148.29 ˚C

  • Synonyms

    • Tyrosol
    • 2-(4-Hydroxyphenyl)ethanol
    • 501-94-0
    • 4-Hydroxyphenethyl alcohol
    • 4-(2-Hydroxyethyl)phenol
    • 4-Hydroxyphenylethanol
    • 4-Hydroxybenzeneethanol
    • p-Hydroxyphenethyl alcohol
    • Benzeneethanol, 4-hydroxy-
    • p-Tyrosol
    • 4-Hydroxyphenylethyl alcohol
    • Tyrosol C
    • MFCD00002902
    • 2-(4-Hydroxyphenyl)ethyl Alcohol
    • NSC 59876
    • p-Thyrosol
    • UNII-1AK4MU3SNX
    • 1AK4MU3SNX
    • EINECS 207-930-8
    • beta-(4-Hydroxyphenyl)ethanol
    • CHEBI:1879
    • p-HPEA
    • 2-(P-HYDROXYPHENYL)ETHANOL
    • Metoprolol IMpurity 07
    • 4-hydroxy-Benzeneethanol
    • NSC-59876
    • p-Hydroxyphenylethyl alcohol
    • 4-(2-Hydroxy-ethyl)-phenol
    • CHEMBL53566
    • DTXSID8060111
    • HYDROXYPHENETHYL ALCOHOL, P-
    • p-hydroxyphenylethanol
    • n-tyrosol
    • SMR000857159
    • para-hydroxyphenylethanol
    • 4-hydroxyphenethylalcohol
    • METOPROLOL TARTRATE IMPURITY G (EP IMPURITY)
    • METOPROLOL TARTRATE IMPURITY G [EP IMPURITY]
    • METOPROLOL SUCCINATE IMPURITY G (EP IMPURITY)
    • METOPROLOL SUCCINATE IMPURITY G [EP IMPURITY]
    • 4-tyrosol
    • YRL
    • Tyrosol (Standard)
    • 2-(4-Hydroxyphenyl)ethanol (Tyrosol)
    • 4-hydroxybenzenethanol
    • 4-(Hydroxyethyl)phenol
    • p-Hydroxy-benzeneethanol
    • TYROSOL [MI]
    • b-(p-Hydroxyphenyl)ethanol
    • bmse000173
    • b-(4-Hydroxyphenyl)ethanol
    • 4-Hydroxyphenylmethylcarbinol
    • 2-(p-hydroxyphenyl) ethanol
    • SCHEMBL43838
    • (4-Hydroxyphenethyl) alcohol
    • 2-(4-hydroxyphenyl) ethanol
    • 2-(4-hydroxyphenyl)-ethanol
    • beta-(p-Hydroxyphenyl)ethanol
    • MLS001332423
    • MLS001332424
    • Phenethyl alcohol, p-hydroxy-
    • Ethanol, 2-(4-hydroxyphenyl)
    • DTXCID7040780
    • SCHEMBL10620528
    • .beta.-(p-Hydroxyphenyl)ethanol
    • 2-(4-Hydroxyphenyl)-1-ethanol
    • Ethanol, 2-(4-hydroxyphenyl)-
    • HY-N0474R
    • .beta.-(4-Hydroxyphenyl)ethanol
    • 4-Hydroxyphenethyl alcohol [ISO]
    • HMS2230E12
    • 2-(4-Hydroxyphenyl)ethanol, 98%
    • BCP34277
    • HY-N0474
    • NSC59876
    • STR02735
    • BDBM50339585
    • s3773
    • AKOS000280287
    • AC-2493
    • CCG-266147
    • CS-W019782
    • FH15593
    • KS-5274
    • NCGC00246994-01
    • NCGC00246994-03
    • SY001653
    • DB-019455
    • Tyrosol;2-(4-Hydroxyphenyl)ethanol;p-HPEA
    • H0720
    • NS00014657
    • C06044
    • EN300-116733
    • TYROSOL (CONSTITUENT OF RHODIOLA ROSEA)
    • 2-(4-Hydroxyphenyl)ethanol, analytical standard
    • NSC 59876; p-HPEA;4-Hydroxyphenethyl alcohol
    • Q402607
    • TYROSOL (CONSTITUENT OF RHODIOLA ROSEA) [DSC]
    • F0001-1309
    • Z1250886919
    • 947D0361-23C6-4863-8346-22AB05108AC5
    • 4-hydroxy-Benzeneethanol;4-Hydroxyphenylethanol;beta-(4-Hydroxyphenyl)ethanol
    • InChI=1/C8H10O2/c9-6-5-7-1-3-8(10)4-2-7/h1-4,9-10H,5-6H
    • 207-930-8

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 884.66
    methanol 1402.38
    isopropanol 504.91
    water 25.13
    ethyl acetate 203.16
    n-propanol 578.46
    acetone 543.61
    n-butanol 409.41
    acetonitrile 202.65
    DMF 586.58
    toluene 28.61
    isobutanol 326.15
    1,4-dioxane 367.61
    methyl acetate 272.8
    THF 584.02
    2-butanone 346.84
    n-pentanol 212.97
    sec-butanol 345.93
    n-hexane 6.53
    ethylene glycol 541.29
    NMP 501.92
    cyclohexane 6.16
    DMSO 1698.73
    n-butyl acetate 119.26
    n-octanol 66.94
    chloroform 50.81
    n-propyl acetate 129.43
    acetic acid 530.18
    dichloromethane 55.07
    cyclohexanone 285.81
    propylene glycol 416.79
    isopropyl acetate 87.77
    DMAc 454.16
    2-ethoxyethanol 486.91
    isopentanol 290.39
    n-heptane 8.03
    ethyl formate 178.97
    1,2-dichloroethane 77.35
    n-hexanol 231.87
    2-methoxyethanol 960.44
    isobutyl acetate 55.54
    tetrachloromethane 39.68
    n-pentyl acetate 51.76
    transcutol 636.34
    n-heptanol 82.82
    ethylbenzene 19.93
    MIBK 122.41
    2-propoxyethanol 371.79
    tert-butanol 662.0
    MTBE 176.89
    2-butoxyethanol 167.86
    propionic acid 497.23
    o-xylene 31.22
    formic acid 561.7
    diethyl ether 117.17
    m-xylene 32.37
    p-xylene 22.57
    chlorobenzene 35.75
    dimethyl carbonate 93.16
    n-octane 2.62
    formamide 908.06
    cyclopentanone 506.39
    2-pentanone 239.89
    anisole 94.91
    cyclopentyl methyl ether 209.71
    gamma-butyrolactone 561.12
    1-methoxy-2-propanol 501.33
    pyridine 138.9
    3-pentanone 129.26
    furfural 336.21
    n-dodecane 1.98
    diethylene glycol 423.2
    diisopropyl ether 33.26
    tert-amyl alcohol 383.76
    acetylacetone 227.55
    n-hexadecane 2.19
    acetophenone 92.21
    methyl propionate 201.43
    isopentyl acetate 88.61
    trichloroethylene 140.49
    n-nonanol 53.63
    cyclohexanol 202.55
    benzyl alcohol 114.41
    2-ethylhexanol 95.72
    isooctanol 61.34
    dipropyl ether 72.85
    1,2-dichlorobenzene 41.08
    ethyl lactate 92.7
    propylene carbonate 200.8
    n-methylformamide 695.5
    2-pentanol 191.21
    n-pentane 6.24
    1-propoxy-2-propanol 217.68
    1-methoxy-2-propyl acetate 128.45
    2-(2-methoxypropoxy) propanol 143.87
    mesitylene 21.26
    ε-caprolactone 242.32
    p-cymene 21.59
    epichlorohydrin 456.47
    1,1,1-trichloroethane 80.6
    2-aminoethanol 740.97
    morpholine-4-carbaldehyde 427.92
    sulfolane 695.48
    2,2,4-trimethylpentane 5.97
    2-methyltetrahydrofuran 396.13
    n-hexyl acetate 79.51
    isooctane 5.2
    2-(2-butoxyethoxy)ethanol 218.15
    sec-butyl acetate 60.29
    tert-butyl acetate 120.17
    decalin 5.5
    glycerin 552.89
    diglyme 364.51
    acrylic acid 400.22
    isopropyl myristate 26.15
    n-butyric acid 395.9
    acetyl acetate 82.32
    di(2-ethylhexyl) phthalate 37.01
    ethyl propionate 98.24
    nitromethane 756.24
    1,2-diethoxyethane 107.9
    benzonitrile 79.09
    trioctyl phosphate 30.29
    1-bromopropane 31.35
    gamma-valerolactone 504.93
    n-decanol 38.91
    triethyl phosphate 41.54
    4-methyl-2-pentanol 91.35
    propionitrile 156.17
    vinylene carbonate 148.89
    1,1,2-trichlorotrifluoroethane 358.7
    DMS 67.79
    cumene 17.81
    2-octanol 41.89
    2-hexanone 140.25
    octyl acetate 39.06
    limonene 32.97
    1,2-dimethoxyethane 442.12
    ethyl orthosilicate 39.86
    tributyl phosphate 34.63
    diacetone alcohol 278.7
    N,N-dimethylaniline 60.7
    acrylonitrile 211.89
    aniline 116.51
    1,3-propanediol 743.1
    bromobenzene 23.71
    dibromomethane 34.76
    1,1,2,2-tetrachloroethane 119.08
    2-methyl-cyclohexyl acetate 60.32
    tetrabutyl urea 48.92
    diisobutyl methanol 47.11
    2-phenylethanol 114.69
    styrene 21.42
    dioctyl adipate 44.92
    dimethyl sulfate 197.59
    ethyl butyrate 80.56
    methyl lactate 175.56
    butyl lactate 71.47
    diethyl carbonate 51.05
    propanediol butyl ether 169.69
    triethyl orthoformate 55.01
    p-tert-butyltoluene 21.96
    methyl 4-tert-butylbenzoate 81.68
    morpholine 532.46
    tert-butylamine 242.74
    n-dodecanol 27.27
    dimethoxymethane 317.68
    ethylene carbonate 130.74
    cyrene 144.25
    2-ethoxyethyl acetate 87.75
    2-ethylhexyl acetate 61.2
    1,2,4-trichlorobenzene 56.3
    4-methylpyridine 123.79
    dibutyl ether 38.88
    2,6-dimethyl-4-heptanol 47.11
    DEF 225.85
    dimethyl isosorbide 192.73
    tetrachloroethylene 113.16
    eugenol 92.64
    triacetin 79.22
    span 80 106.47
    1,4-butanediol 260.81
    1,1-dichloroethane 55.97
    2-methyl-1-pentanol 158.31
    methyl formate 409.99
    2-methyl-1-butanol 271.69
    n-decane 3.47
    butyronitrile 136.69
    3,7-dimethyl-1-octanol 63.78
    1-chlorooctane 19.01
    1-chlorotetradecane 6.41
    n-nonane 3.35
    undecane 2.56
    tert-butylcyclohexane 6.85
    cyclooctane 3.08
    cyclopentanol 327.73
    tetrahydropyran 227.27
    tert-amyl methyl ether 121.67
    2,5,8-trioxanonane 237.83
    1-hexene 25.62
    2-isopropoxyethanol 256.04
    2,2,2-trifluoroethanol 204.88
    methyl butyrate 154.07

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Cassia, bark (China) 4a 8007-80-5 Cinnamomum cassia Blume, fam. Lauraceae 0.05%
Cassia, leaf (China) 4b 8007-80-5 Cinnamomum cassia Blume, fam. Lauraceae 0.06%