Tris(2-carboxyethyl)phosphine hydrochloride

Overview IFRA Request a quote

  • Identifiers

    CAS number
    51805-45-9

    Molecular formula
    C9H16ClO6P

    SMILES
    C(CP(CCC(=O)O)CCC(=O)O)C(=O)O.Cl

    Safety labels

    Corrosive
    Corrosive

  • Odor profile

    Odorless 75.27%
    Cheesy 35.54%
    Sour 32.43%
    Meaty 27.94%
    Savory 27.76%
    Sulfurous 21.08%
    Milky 19.56%
    Cooked 18.78%
    Roasted 18.6%
    Dairy 17.13%

    Scent© AI

  • Properties

    Molecular weight
    286.64 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    430°C

    Flash point est.
    189.61 ˚C

  • Synonyms

    • 51805-45-9
    • Tris(2-carboxyethyl)phosphine hydrochloride
    • TCEP Hydrochloride
    • 3,3',3''-Phosphinetriyltripropanoic acid hydrochloride
    • TCEP HCl
    • Tcep hydrochloride [MI]
    • TCEP (hydrochloride)
    • MFCD00145469
    • Tris(2-carboxyethyl)phosphine, HCl
    • UNII-H49AAM893K
    • H49AAM893K
    • Tris(carboxyethyl)phosphine hydrochloride
    • tris-(2-carboxyethyl)phosphine hydrochloride
    • 3-[bis(2-carboxyethyl)phosphanyl]propanoic acid;hydrochloride
    • DTXSID10370367
    • Propanoic acid, 3,3',3''-phosphinylidynetris-, hydrochloride (1:1)
    • TRIS(2-CARBOXYETHYL)PHOSPHINE HCL
    • tris-(carboxyethyl)phosphine hydrochloride
    • TCEP Hydrochloride (0.5M in water)
    • CHEMBL2047686
    • TCEP Hydrochloride?
    • TCEP, Hydrochloride
    • TCEP-HCl
    • 3-[bis(2-carboxyethyl)phosphanyl]propanoic acid hydrochloride
    • Propanoic acid, 3,3',3''-phosphinidynetris-, hydrochloride
    • C9H16ClO6P
    • SCHEMBL61373
    • P(CH2CH2CO2H)3.HCl
    • DTXCID80321402
    • BCP27832
    • s4611
    • AKOS016008718
    • CS-W012216
    • FT01756
    • HY-W011500
    • Tris-carboxyethylphosphine hydrochloride
    • AS-19130
    • SY010484
    • tri(2-carboxyethyl)phosphine hydrochloride
    • tris(2-carboxyethyl)phosphine-hydrochloride
    • DB-009894
    • NS00074318
    • T1656
    • 3,3',3''-Phosphinetriyltripropanoic acid HCl
    • M02624
    • M02706
    • EN300-1724932
    • Tris(2-carboxyethyl)phosphine hydrochloride (1:1)
    • Q27279627
    • Z1741982651
    • TCEP*HCl;TRIS(2-CARBOXYETHYL)PHOSPHINE HYDROCHLORIDE
    • Tris(2-carboxyethyl)phosphine hydrochloride, powder, >=98%
    • Tris(2-carboxyethyl)phosphine hydrochloride, BioUltra, >=98% (NMR)
    • Tris(2-carboxyethyl)phosphine hydrochloride, purum, >=98.0% (C)
    • TCEP HCl;TCEP Hydrochloride;3,3',3''-Phosphinetriyltripropanoic acid hydrochloride
    • Tris(2-carboxyethyl)phosphine hydrochloride, BioUltra, for electrophoresis, SDS-PAGE tested
    • 629-759-1
    • TCEP;Tris(carboxyethyl)phosphine HCl;3,3?,3??-Phosphinidynetris-propanoic acid hydrochloride

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 36.08
    methanol 88.13
    isopropanol 18.65
    water 161.53
    ethyl acetate 5.2
    n-propanol 24.6
    acetone 15.91
    n-butanol 16.77
    acetonitrile 6.05
    DMF 134.63
    toluene 2.24
    isobutanol 11.14
    1,4-dioxane 21.39
    methyl acetate 4.46
    THF 43.42
    2-butanone 6.7
    n-pentanol 11.61
    sec-butanol 10.66
    n-hexane 2.16
    ethylene glycol 72.2
    NMP 97.68
    cyclohexane 2.12
    DMSO 137.44
    n-butyl acetate 4.05
    n-octanol 5.82
    chloroform 2.92
    n-propyl acetate 4.85
    acetic acid 18.88
    dichloromethane 4.75
    cyclohexanone 13.74
    propylene glycol 40.96
    isopropyl acetate 4.12
    DMAc 111.82
    2-ethoxyethanol 59.19
    isopentanol 9.89
    n-heptane 2.44
    ethyl formate 11.43
    1,2-dichloroethane 6.18
    n-hexanol 9.24
    2-methoxyethanol 113.22
    isobutyl acetate 1.96
    tetrachloromethane 1.25
    n-pentyl acetate 4.49
    transcutol 34.11
    n-heptanol 8.63
    ethylbenzene 2.15
    MIBK 4.88
    2-propoxyethanol 41.85
    tert-butanol 17.44
    MTBE 3.61
    2-butoxyethanol 27.16
    propionic acid 13.72
    o-xylene 3.71
    formic acid 86.18
    diethyl ether 7.36
    m-xylene 2.83
    p-xylene 2.58
    chlorobenzene 1.07
    dimethyl carbonate 7.29
    n-octane 1.46
    formamide 114.63
    cyclopentanone 22.43
    2-pentanone 8.64
    anisole 3.26
    cyclopentyl methyl ether 11.88
    gamma-butyrolactone 33.45
    1-methoxy-2-propanol 57.11
    pyridine 8.72
    3-pentanone 6.66
    furfural 27.09
    n-dodecane 0.74
    diethylene glycol 66.87
    diisopropyl ether 2.26
    tert-amyl alcohol 10.29
    acetylacetone 9.02
    n-hexadecane 0.8
    acetophenone 5.56
    methyl propionate 8.78
    isopentyl acetate 3.15
    trichloroethylene 3.77
    n-nonanol 5.99
    cyclohexanol 10.68
    benzyl alcohol 7.51
    2-ethylhexanol 4.31
    isooctanol 5.31
    dipropyl ether 7.49
    1,2-dichlorobenzene 1.48
    ethyl lactate 9.87
    propylene carbonate 10.17
    n-methylformamide 71.49
    2-pentanol 8.17
    n-pentane 2.0
    1-propoxy-2-propanol 21.58
    1-methoxy-2-propyl acetate 7.46
    2-(2-methoxypropoxy) propanol 16.13
    mesitylene 2.46
    ε-caprolactone 14.38
    p-cymene 2.14
    epichlorohydrin 21.63
    1,1,1-trichloroethane 1.6
    2-aminoethanol 82.64
    morpholine-4-carbaldehyde 69.02
    sulfolane 51.52
    2,2,4-trimethylpentane 0.55
    2-methyltetrahydrofuran 12.24
    n-hexyl acetate 4.47
    isooctane 0.37
    2-(2-butoxyethoxy)ethanol 25.38
    sec-butyl acetate 2.52
    tert-butyl acetate 4.14
    decalin 0.95
    glycerin 96.13
    diglyme 35.68
    acrylic acid 14.7
    isopropyl myristate 2.33
    n-butyric acid 12.63
    acetyl acetate 2.56
    di(2-ethylhexyl) phthalate 3.62
    ethyl propionate 5.76
    nitromethane 24.21
    1,2-diethoxyethane 8.19
    benzonitrile 3.39
    trioctyl phosphate 3.62
    1-bromopropane 3.6
    gamma-valerolactone 44.08
    n-decanol 4.89
    triethyl phosphate 3.81
    4-methyl-2-pentanol 4.25
    propionitrile 5.48
    vinylene carbonate 8.49
    1,1,2-trichlorotrifluoroethane 25.46
    DMS 4.56
    cumene 2.01
    2-octanol 4.9
    2-hexanone 5.02
    octyl acetate 3.41
    limonene 2.38
    1,2-dimethoxyethane 49.0
    ethyl orthosilicate 4.06
    tributyl phosphate 3.41
    diacetone alcohol 13.15
    N,N-dimethylaniline 6.47
    acrylonitrile 8.07
    aniline 5.17
    1,3-propanediol 57.46
    bromobenzene 0.82
    dibromomethane 3.43
    1,1,2,2-tetrachloroethane 6.55
    2-methyl-cyclohexyl acetate 3.98
    tetrabutyl urea 8.23
    diisobutyl methanol 3.19
    2-phenylethanol 6.85
    styrene 1.71
    dioctyl adipate 3.63
    dimethyl sulfate 15.85
    ethyl butyrate 4.58
    methyl lactate 19.08
    butyl lactate 9.46
    diethyl carbonate 3.14
    propanediol butyl ether 21.4
    triethyl orthoformate 4.99
    p-tert-butyltoluene 2.1
    methyl 4-tert-butylbenzoate 8.63
    morpholine 34.13
    tert-butylamine 7.79
    n-dodecanol 3.89
    dimethoxymethane 53.71
    ethylene carbonate 8.09
    cyrene 22.59
    2-ethoxyethyl acetate 6.03
    2-ethylhexyl acetate 2.53
    1,2,4-trichlorobenzene 1.7
    4-methylpyridine 7.2
    dibutyl ether 3.86
    2,6-dimethyl-4-heptanol 3.19
    DEF 23.23
    dimethyl isosorbide 24.47
    tetrachloroethylene 5.19
    eugenol 13.11
    triacetin 5.53
    span 80 14.12
    1,4-butanediol 30.66
    1,1-dichloroethane 2.42
    2-methyl-1-pentanol 6.56
    methyl formate 37.29
    2-methyl-1-butanol 8.95
    n-decane 1.18
    butyronitrile 5.61
    3,7-dimethyl-1-octanol 3.3
    1-chlorooctane 1.99
    1-chlorotetradecane 1.09
    n-nonane 1.21
    undecane 0.91
    tert-butylcyclohexane 0.62
    cyclooctane 1.38
    cyclopentanol 17.99
    tetrahydropyran 10.0
    tert-amyl methyl ether 4.65
    2,5,8-trioxanonane 31.72
    1-hexene 3.45
    2-isopropoxyethanol 22.66
    2,2,2-trifluoroethanol 17.43
    methyl butyrate 7.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction