Trimethylchlorosilane

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  • Identifiers

    CAS number
    75-77-4

    Molecular formula
    C3H9ClSi

    SMILES
    C[Si](C)(C)Cl

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fishy 38.73%
    Camphoreous 35.7%
    Mint 31.57%
    Fermented 26.85%
    Musty 24.24%
    Cheesy 24.14%
    Pungent 23.56%
    Solvent 23.25%
    Woody 23.05%
    Fresh 22.86%

    Scent© AI

  • Properties

    Molecular weight
    108.64 g/mol

    Melting point expt.

    • -72 °F (EPA, 1998)
    • -40 °C
    • -58 °C

    Boiling point

    • 135 °F at 760 mmHg (EPA, 1998)
    • 57 °C

    Flash point est.
    -18.84 ˚C

    Flash point expt.

    • 0 °F (EPA, 1998)
    • [ERG 2016] -28 °C
    • -18 °F (-28 °C) (Closed cup)
    • 0 °F (Open cup)
    • -27 °C

    Solubility expt.

    • Decomposes (NTP, 1992)
    • Sol in benzene, ether, perchloroethylene
    • Solubility in water: reaction

  • Synonyms

    • Chlorotrimethylsilane
    • 75-77-4
    • TRIMETHYLCHLOROSILANE
    • Trimethylsilyl chloride
    • chloro(trimethyl)silane
    • Silane, chlorotrimethyl-
    • Trimethyl chlorosilane
    • Monochlorotrimethylsilicon
    • TMCS
    • Silane, trimethylchloro-
    • Silicane, chlorotrimethyl-
    • TMSCl
    • Silylium, trimethyl-, chloride
    • (CH3)3SiCl
    • Me3SiCl
    • TL 1163
    • TMS-Cl
    • CCRIS 790
    • NSC 15750
    • trimethylsilane chloride
    • monochlorotrimethylsilane
    • HSDB 1009
    • EINECS 200-900-5
    • MFCD00000502
    • BRN 1209232
    • chlorotrimethyl silane
    • DTXSID2024822
    • UNII-62UO4690X6
    • CHEBI:85069
    • Chloro-trimethyl-silane
    • trimethyl silyl chloride
    • NSC-15750
    • 62UO4690X6
    • DTXCID404822
    • EC 200-900-5
    • KA 31
    • 4-04-00-04007 (Beilstein Handbook Reference)
    • TSL 8031
    • TMCS; Trimethylchlorosilane
    • chloro-trimethylsilane
    • UN1298
    • TMS chloride
    • TMS-chloride
    • trimethylchlorsilan
    • chlorotrimethlsilane
    • chlorotrimethylsilan
    • chlorotrimethysilane
    • chlorotrimetylsilane
    • chlortrimethylsilane
    • chorotrimethylsilane
    • Silylium, chloride
    • trimethylchlorosilan
    • trimethylchlorsilane
    • trimethylchorosilane
    • ClSiMe3
    • SiMe3Cl
    • chiorotrimethylsilane
    • trimethyichlorosilane
    • trimethylchiorosilane
    • trimethylsilylchoride
    • trimethysilylchloride
    • trimethyl-chlorsilane
    • Trimethylsilylchloride
    • chloro trimethylsilane
    • chlorotrimethyl-silane
    • trimethyl-chlorosilane
    • trimethylchloro silane
    • trimethysilyl chloride
    • Chlorotrimethylsilicane
    • trimehtylsilyl chloride
    • trimethylsilyl-chloride
    • 20395-57-7
    • Trimethyl silylchloride
    • chloro trimethyl silane
    • chloro-trimethyl silane
    • trimethyl(chlorosilane)
    • trimethyl-chloro-silane
    • tri-methylsilyl chloride
    • trimethyl-silyl chloride
    • trimethylsilanyl chloride
    • trimethylsilicon chloride
    • chloro(trimethyl)-silane
    • chloranyl(trimethyl)silane
    • SCHEMBL1319
    • Chlorotrimethylsilane (TMCS)
    • Trimethylsilyl chloride, TMCS
    • Chlorotrimethylsilane, >=97%
    • SILICANE, CHLOROTRIMETHYL
    • CHEMBL1505385
    • CHLOROTRIMETHYLSILANE [MI]
    • WLN: G-SI-1&1&1
    • BCP30036
    • NSC15750
    • Tox21_200221
    • STL185543
    • AKOS000120043
    • FT02586
    • UN 1298
    • CAS-75-77-4
    • Chlorotrimethylsilane, >=98.0% (GC)
    • NCGC00091812-01
    • NCGC00091812-02
    • NCGC00257775-01
    • BP-21151
    • Chlorotrimethylsilane;Trimethyl chlorosilane
    • DB-031359
    • NS00041128
    • Chlorotrimethylsilane, puriss., >=99.0% (GC)
    • A838505
    • Q420183
    • Trimethylchlorosilane [UN1298] [Flammable liquid]
    • Chlorotrimethylsilane, purified by redistillation, >=99%
    • F0001-1904
    • TMSCl;Chlorotrimethylsilane;Trimethylsilyl chloride;TMCS
    • Chlorotrimethylsilane, for GC derivatization, >=99.0% (GC)
    • Chlorotrimethylsilane, produced by Wacker Chemie AG, Burghausen, Germany, >=99.0% (GC)
    • 200-900-5

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 440.7
    methanol 464.48
    isopropanol 350.28
    water 9.69
    ethyl acetate 232.76
    n-propanol 374.66
    acetone 377.69
    n-butanol 369.51
    acetonitrile 176.79
    DMF 394.36
    toluene 201.72
    isobutanol 262.69
    1,4-dioxane 393.4
    methyl acetate 212.28
    THF 799.24
    2-butanone 344.64
    n-pentanol 285.8
    sec-butanol 335.54
    n-hexane 234.55
    ethylene glycol 141.69
    NMP 406.72
    cyclohexane 266.33
    DMSO 346.85
    n-butyl acetate 299.93
    n-octanol 339.65
    chloroform 358.89
    n-propyl acetate 194.24
    acetic acid 246.46
    dichloromethane 238.75
    cyclohexanone 436.64
    propylene glycol 219.53
    isopropyl acetate 197.7
    DMAc 319.01
    2-ethoxyethanol 294.67
    isopentanol 266.81
    n-heptane 340.84
    ethyl formate 144.09
    1,2-dichloroethane 190.4
    n-hexanol 508.23
    2-methoxyethanol 445.12
    isobutyl acetate 158.15
    tetrachloromethane 127.22
    n-pentyl acetate 243.37
    transcutol 585.18
    n-heptanol 333.9
    ethylbenzene 125.09
    MIBK 229.26
    2-propoxyethanol 545.65
    tert-butanol 362.49
    MTBE 293.58
    2-butoxyethanol 378.28
    propionic acid 254.16
    o-xylene 148.3
    formic acid 100.54
    diethyl ether 388.27
    m-xylene 176.7
    p-xylene 139.95
    chlorobenzene 168.54
    dimethyl carbonate 114.6
    n-octane 138.08
    formamide 115.52
    cyclopentanone 520.6
    2-pentanone 339.93
    anisole 190.31
    cyclopentyl methyl ether 479.14
    gamma-butyrolactone 393.92
    1-methoxy-2-propanol 429.64
    pyridine 272.94
    3-pentanone 278.18
    furfural 301.74
    n-dodecane 83.67
    diethylene glycol 310.21
    diisopropyl ether 186.55
    tert-amyl alcohol 311.53
    acetylacetone 276.59
    n-hexadecane 89.47
    acetophenone 171.22
    methyl propionate 227.89
    isopentyl acetate 250.68
    trichloroethylene 269.59
    n-nonanol 295.37
    cyclohexanol 371.33
    benzyl alcohol 148.52
    2-ethylhexanol 324.14
    isooctanol 233.91
    dipropyl ether 468.72
    1,2-dichlorobenzene 140.72
    ethyl lactate 133.35
    propylene carbonate 221.94
    n-methylformamide 213.19
    2-pentanol 320.98
    n-pentane 226.77
    1-propoxy-2-propanol 523.22
    1-methoxy-2-propyl acetate 268.32
    2-(2-methoxypropoxy) propanol 244.25
    mesitylene 144.88
    ε-caprolactone 324.34
    p-cymene 141.82
    epichlorohydrin 316.09
    1,1,1-trichloroethane 217.08
    2-aminoethanol 256.92
    morpholine-4-carbaldehyde 371.06
    sulfolane 429.88
    2,2,4-trimethylpentane 85.31
    2-methyltetrahydrofuran 512.46
    n-hexyl acetate 323.19
    isooctane 85.8
    2-(2-butoxyethoxy)ethanol 356.68
    sec-butyl acetate 152.82
    tert-butyl acetate 239.0
    decalin 100.18
    glycerin 248.34
    diglyme 501.99
    acrylic acid 207.25
    isopropyl myristate 174.39
    n-butyric acid 295.67
    acetyl acetate 149.66
    di(2-ethylhexyl) phthalate 124.32
    ethyl propionate 184.9
    nitromethane 230.61
    1,2-diethoxyethane 317.64
    benzonitrile 156.01
    trioctyl phosphate 122.47
    1-bromopropane 237.77
    gamma-valerolactone 467.78
    n-decanol 224.68
    triethyl phosphate 119.82
    4-methyl-2-pentanol 192.42
    propionitrile 202.55
    vinylene carbonate 178.39
    1,1,2-trichlorotrifluoroethane 247.83
    DMS 148.11
    cumene 101.58
    2-octanol 264.71
    2-hexanone 269.32
    octyl acetate 216.57
    limonene 229.91
    1,2-dimethoxyethane 373.53
    ethyl orthosilicate 129.86
    tributyl phosphate 124.66
    diacetone alcohol 284.59
    N,N-dimethylaniline 165.35
    acrylonitrile 187.58
    aniline 209.35
    1,3-propanediol 279.6
    bromobenzene 161.04
    dibromomethane 243.85
    1,1,2,2-tetrachloroethane 274.19
    2-methyl-cyclohexyl acetate 209.18
    tetrabutyl urea 178.78
    diisobutyl methanol 203.55
    2-phenylethanol 219.45
    styrene 138.82
    dioctyl adipate 183.82
    dimethyl sulfate 141.7
    ethyl butyrate 237.6
    methyl lactate 169.85
    butyl lactate 211.53
    diethyl carbonate 135.55
    propanediol butyl ether 339.64
    triethyl orthoformate 199.86
    p-tert-butyltoluene 154.12
    methyl 4-tert-butylbenzoate 224.2
    morpholine 472.29
    tert-butylamine 287.69
    n-dodecanol 180.9
    dimethoxymethane 331.67
    ethylene carbonate 164.36
    cyrene 205.45
    2-ethoxyethyl acetate 222.07
    2-ethylhexyl acetate 230.14
    1,2,4-trichlorobenzene 165.13
    4-methylpyridine 252.86
    dibutyl ether 331.28
    2,6-dimethyl-4-heptanol 203.55
    DEF 276.56
    dimethyl isosorbide 349.31
    tetrachloroethylene 208.51
    eugenol 213.49
    triacetin 232.13
    span 80 308.88
    1,4-butanediol 145.3
    1,1-dichloroethane 223.46
    2-methyl-1-pentanol 204.75
    methyl formate 148.46
    2-methyl-1-butanol 273.23
    n-decane 137.36
    butyronitrile 213.83
    3,7-dimethyl-1-octanol 260.77
    1-chlorooctane 236.13
    1-chlorotetradecane 110.79
    n-nonane 152.38
    undecane 101.98
    tert-butylcyclohexane 99.23
    cyclooctane 160.69
    cyclopentanol 388.68
    tetrahydropyran 536.81
    tert-amyl methyl ether 273.78
    2,5,8-trioxanonane 356.81
    1-hexene 312.4
    2-isopropoxyethanol 231.86
    2,2,2-trifluoroethanol 105.7
    methyl butyrate 207.7

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction