Trientine

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  • Identifiers

    CAS number
    112-24-3

    Molecular formula
    C6H18N4

    SMILES
    C(CNCCNCCN)N

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fishy 82.66%
    Odorless 39.38%
    Cheesy 37.13%
    Ripe 36.53%
    Animal 27.87%
    Meaty 17.72%
    Savory 17.56%
    Pungent 15.47%
    Oily 14.39%
    Alcoholic 12.99%

    Scent© AI

  • Properties

    XLogP3-AA
    -2.5

    Molecular weight
    146.23 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 54 °F (NTP, 1992)
    • 12 undefined
    • 12 °C
    • -35 °C
    • 54 °F

    Boiling point

    • 511 to 513 °F at 760 mmHg (NTP, 1992)
    • 266-267
    • 266-267 °C @ 760 MM HG
    • 277 °C
    • 511-513 °F

    Flash point est.
    139.28 ˚C

    Flash point expt.

    • 275 °F (NTP, 1992)
    • 290 °F
    • 135 °C c.c.
    • 275 °F

    Solubility expt.

    • greater than or equal to 100 mg/mL at 68.4 °F (NTP, 1992)
    • Soluble
    • SOL IN ALCOHOL, ACID
    • COMPLETE SOLUBILITY IN WATER
    • Solubility in water: miscible

  • Synonyms

    • TRIETHYLENETETRAMINE
    • trientine
    • 112-24-3
    • Trien
    • Triethylene tetramine
    • Tecza
    • 1,2-Ethanediamine, N,N'-bis(2-aminoethyl)-
    • TETA
    • DEH 24
    • Araldite hardener HY 951
    • Trientina
    • Araldite HY 951
    • 1,4,7,10-Tetraazadecane
    • 1,8-Diamino-3,6-diazaoctane
    • Trientinum
    • triethylene tetraamine
    • N,N'-Bis(2-aminoethyl)-1,2-ethanediamine
    • Trethylenetetramine
    • 3,6-Diazaoctane-1,8-diamine
    • N,N'-Bis(2-aminoethyl)ethylenediamine
    • triethylenetetraamine
    • NSC 443
    • Syprine
    • 2,2,2-tetramine
    • HY 951
    • N,N'-bis(2-aminoethyl)ethane-1,2-diamine
    • CCRIS 6279
    • HSDB 1002
    • Trientinum [INN-Latin]
    • NSC-443
    • Trientina [INN-Spanish]
    • Ethylenediamine, N,N'-bis(2-aminoethyl)-
    • N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine
    • EINECS 203-950-6
    • UNII-SJ76Y07H5F
    • MFCD00008169
    • Trientine [INN]
    • BRN 0605448
    • SJ76Y07H5F
    • DTXSID9023702
    • CHEBI:39501
    • AI3-24384
    • N,N-Bis(2-aminoethyl)-1,2-diaminoethane
    • EPH 925
    • Tomography, x-ray computed trientine
    • CHEMBL609
    • (2-aminoethyl)({2-[(2-aminoethyl)amino]ethyl})amine
    • DTXCID503702
    • 4-04-00-01242 (Beilstein Handbook Reference)
    • NCGC00091695-01
    • NCGC00091695-03
    • Trientinum (INN-Latin)
    • N,N'-Bis(2-aminoethyl)-1,2-diaminoethane
    • Trientina (INN-Spanish)
    • 1,2-Ethanediamine, N1,N2-bis(2-aminoethyl)-
    • Triethylenetetramine (Technical Grade)
    • CAS-112-24-3
    • Rutapox VE 2896
    • UN2259
    • RT 1AX
    • TETA (crosslinking agent)
    • Trientene
    • 1,6-diazaoctane
    • 3,8-diamine
    • VE 2896
    • TRIENTINE [MI]
    • 1,7,10-Tetraazadecane
    • TRIENTINE [VANDF]
    • N1,N2-Bis(2-aminoethyl)-1,2-ethanediamine
    • bmse000773
    • Texlin 300 (Salt/Mix)
    • TRIENTINE [WHO-DD]
    • 3,6-Diazaoctanethylenediamin
    • SCHEMBL15439
    • WLN: Z2M2M2Z
    • BIDD:ER0303
    • BIDD:GT0014
    • NSC443
    • SCHEMBL6423840
    • A16AX12
    • TRIETHYLENETETRAMINE [HSDB]
    • n,n'-bis(aminoethyl)ethylenediamine
    • STR03562
    • n,n'-bis(2-aminoethyl)ethanediamine
    • Tox21_111162
    • Tox21_201066
    • BDBM50323751
    • STL477736
    • N,N'-Di(2-aminoethyl)ethylenediamine
    • AKOS006223906
    • ethane, 1,2-bis(2-aminoethyl)amino-
    • ethane, 1,2-bis(2-aminoethylamino)-
    • Tox21_111162_1
    • Triethylenetetramine, >=97.0% (T)
    • DB06824
    • Ethylenediamine,N'-bis(2-aminoethyl)-
    • FT37067
    • NCGC00091695-04
    • NCGC00258619-01
    • BP-30180
    • Ethanediamine, N,N'-bis(2-aminoethyl)-
    • SBI-0206814.P001
    • DB-041060
    • Triethylenetetramine, technical grade, 60%
    • NS00001757
    • T0429
    • Triethylenetetramine [UN2259] [Corrosive]
    • C07166
    • EN300-651158
    • N,N'-BIS-(2-AMINOETHYL)ETHYLENEDIAMINE
    • AB00573244_07
    • N,N''-Bis-(2-amino-ethyl)-ethane-1,2-diamine
    • N1,N1'-(Ethane-1,2-diyl)diethane-1,2-diamine
    • Q418386
    • N,N''-BIS(2-AMINOETHYL)-1,2-ETHANEDIAMINE
    • BRD-K37111771-300-02-6
    • 105821-86-1
    • 203-950-6

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 88.71
    methanol 481.79
    isopropanol 16.67
    water 1689.86
    ethyl acetate 6.29
    n-propanol 50.36
    acetone 6.83
    n-butanol 25.82
    acetonitrile 8.55
    DMF 123.66
    toluene 1.15
    isobutanol 18.45
    1,4-dioxane 14.34
    methyl acetate 7.42
    THF 38.05
    2-butanone 6.11
    n-pentanol 10.01
    sec-butanol 11.8
    n-hexane 0.35
    ethylene glycol 424.01
    NMP 274.06
    cyclohexane 1.11
    DMSO 325.73
    n-butyl acetate 8.48
    n-octanol 2.97
    chloroform 14.86
    n-propyl acetate 4.44
    acetic acid 637.96
    dichloromethane 14.56
    cyclohexanone 25.27
    propylene glycol 186.5
    isopropyl acetate 2.69
    DMAc 75.3
    2-ethoxyethanol 58.72
    isopentanol 9.0
    n-heptane 1.02
    ethyl formate 32.16
    1,2-dichloroethane 8.34
    n-hexanol 12.24
    2-methoxyethanol 210.59
    isobutyl acetate 2.34
    tetrachloromethane 6.54
    n-pentyl acetate 4.12
    transcutol 42.27
    n-heptanol 7.05
    ethylbenzene 0.43
    MIBK 1.35
    2-propoxyethanol 58.71
    tert-butanol 8.87
    MTBE 1.4
    2-butoxyethanol 34.41
    propionic acid 164.24
    o-xylene 1.09
    formic acid 2115.19
    diethyl ether 2.19
    m-xylene 0.82
    p-xylene 0.65
    chlorobenzene 3.65
    dimethyl carbonate 8.11
    n-octane 0.33
    formamide 996.71
    cyclopentanone 48.97
    2-pentanone 3.85
    anisole 1.57
    cyclopentyl methyl ether 10.22
    gamma-butyrolactone 125.72
    1-methoxy-2-propanol 59.92
    pyridine 21.02
    3-pentanone 4.0
    furfural 167.39
    n-dodecane 0.16
    diethylene glycol 133.4
    diisopropyl ether 0.44
    tert-amyl alcohol 8.55
    acetylacetone 6.2
    n-hexadecane 0.16
    acetophenone 3.94
    methyl propionate 11.38
    isopentyl acetate 4.86
    trichloroethylene 17.89
    n-nonanol 2.68
    cyclohexanol 19.28
    benzyl alcohol 9.24
    2-ethylhexanol 4.82
    isooctanol 4.05
    dipropyl ether 3.79
    1,2-dichlorobenzene 4.54
    ethyl lactate 15.67
    propylene carbonate 50.14
    n-methylformamide 236.92
    2-pentanol 5.5
    n-pentane 0.5
    1-propoxy-2-propanol 27.96
    1-methoxy-2-propyl acetate 11.05
    2-(2-methoxypropoxy) propanol 11.25
    mesitylene 0.55
    ε-caprolactone 35.99
    p-cymene 1.29
    epichlorohydrin 40.66
    1,1,1-trichloroethane 3.54
    2-aminoethanol 339.66
    morpholine-4-carbaldehyde 145.46
    sulfolane 308.64
    2,2,4-trimethylpentane 0.28
    2-methyltetrahydrofuran 13.34
    n-hexyl acetate 3.35
    isooctane 0.12
    2-(2-butoxyethoxy)ethanol 19.02
    sec-butyl acetate 1.81
    tert-butyl acetate 2.19
    decalin 0.31
    glycerin 511.72
    diglyme 33.96
    acrylic acid 273.27
    isopropyl myristate 0.97
    n-butyric acid 111.37
    acetyl acetate 7.57
    di(2-ethylhexyl) phthalate 4.63
    ethyl propionate 4.02
    nitromethane 208.88
    1,2-diethoxyethane 3.79
    benzonitrile 6.96
    trioctyl phosphate 3.63
    1-bromopropane 2.59
    gamma-valerolactone 109.26
    n-decanol 1.77
    triethyl phosphate 6.05
    4-methyl-2-pentanol 1.7
    propionitrile 8.93
    vinylene carbonate 55.32
    1,1,2-trichlorotrifluoroethane 223.81
    DMS 5.71
    cumene 0.46
    2-octanol 2.09
    2-hexanone 2.33
    octyl acetate 1.97
    limonene 1.9
    1,2-dimethoxyethane 20.96
    ethyl orthosilicate 5.2
    tributyl phosphate 4.66
    diacetone alcohol 9.38
    N,N-dimethylaniline 1.93
    acrylonitrile 21.73
    aniline 11.61
    1,3-propanediol 204.53
    bromobenzene 2.14
    dibromomethane 7.42
    1,1,2,2-tetrachloroethane 16.41
    2-methyl-cyclohexyl acetate 4.82
    tetrabutyl urea 5.65
    diisobutyl methanol 1.52
    2-phenylethanol 9.48
    styrene 0.7
    dioctyl adipate 2.67
    dimethyl sulfate 36.62
    ethyl butyrate 6.25
    methyl lactate 48.47
    butyl lactate 15.38
    diethyl carbonate 4.77
    propanediol butyl ether 28.89
    triethyl orthoformate 6.78
    p-tert-butyltoluene 1.27
    methyl 4-tert-butylbenzoate 7.58
    morpholine 39.55
    tert-butylamine 3.57
    n-dodecanol 1.3
    dimethoxymethane 18.95
    ethylene carbonate 37.39
    cyrene 37.19
    2-ethoxyethyl acetate 6.39
    2-ethylhexyl acetate 3.99
    1,2,4-trichlorobenzene 6.45
    4-methylpyridine 8.95
    dibutyl ether 1.31
    2,6-dimethyl-4-heptanol 1.52
    DEF 21.95
    dimethyl isosorbide 25.1
    tetrachloroethylene 24.14
    eugenol 14.44
    triacetin 7.75
    span 80 18.85
    1,4-butanediol 68.25
    1,1-dichloroethane 2.99
    2-methyl-1-pentanol 4.59
    methyl formate 107.49
    2-methyl-1-butanol 12.43
    n-decane 0.27
    butyronitrile 7.21
    3,7-dimethyl-1-octanol 1.9
    1-chlorooctane 0.77
    1-chlorotetradecane 0.33
    n-nonane 0.27
    undecane 0.2
    tert-butylcyclohexane 0.23
    cyclooctane 0.4
    cyclopentanol 44.61
    tetrahydropyran 8.56
    tert-amyl methyl ether 1.72
    2,5,8-trioxanonane 21.07
    1-hexene 0.79
    2-isopropoxyethanol 15.91
    2,2,2-trifluoroethanol 315.42
    methyl butyrate 7.38

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction