trans-p-Menth-2-ene-1,4-diol

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  • Identifiers

    CAS number
    40735-19-1

    Molecular formula
    C10H18O2

    SMILES
    CC(C)C1(CCC(C=C1)(C)O)O

  • Odor profile

    Sweet 47.83%
    Mint 43.05%
    Herbal 39.64%
    Woody 39.49%
    Floral 38.12%
    Cooling 34.11%
    Camphoreous 33.97%
    Earthy 32.33%
    Musty 30.65%
    Fresh 28.15%

    Scent© AI

  • Properties

    XLogP3-AA
    1.2

    Molecular weight
    170.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    237°C

    Melting point expt.

    • 101 °C

    Flash point est.
    123.78 ˚C

  • Synonyms

    • trans-p-Menth-2-ene-1,4-diol
    • 40735-19-1
    • 1-methyl-4-(propan-2-yl)cyclohex-2-ene-1,4-diol
    • 1-methyl-4-propan-2-ylcyclohex-2-ene-1,4-diol
    • NSC174183
    • p-menth-2-ene-1,4-diol
    • 1,4-dihydroxy-p-menth-2-ene
    • trans-2-p-Menthene-1,4-diol
    • SCHEMBL11680562
    • DTXSID50306125
    • CHEBI:180236
    • WHOYVNZMAORLBI-UHFFFAOYSA-N
    • NSC-174183

  • Applications

    trans-p-Menth-2-ene-1,4-diol (CAS 40735-19-1) is a monoterpenoid diol researched and used as a flavor and fragrance ingredient and cooling-sensation booster in confectionery, beverages, chewing gum, oral-care and cosmetic products; as a deodorizing/antimicrobial adjunct in personal-care and household cleaners; as a skin-feel modulator and humectant; and as a versatile intermediate/building block for synthesizing menthane/menthene derivatives (cooling agents, aroma chemicals, cosmeceutical actives), as well as being studied for bioactivity (antimicrobial, antioxidant) and used as a technical odor-modifying additive in consumer materials.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 219.12
    methanol 249.2
    isopropanol 184.79
    water 3.45
    ethyl acetate 98.78
    n-propanol 152.73
    acetone 125.86
    n-butanol 144.41
    acetonitrile 119.05
    DMF 197.1
    toluene 48.66
    isobutanol 104.82
    1,4-dioxane 290.42
    methyl acetate 111.47
    THF 399.19
    2-butanone 113.61
    n-pentanol 85.15
    sec-butanol 118.2
    n-hexane 7.51
    ethylene glycol 48.32
    NMP 116.39
    cyclohexane 14.61
    DMSO 147.58
    n-butyl acetate 82.97
    n-octanol 80.35
    chloroform 168.52
    n-propyl acetate 52.87
    acetic acid 86.95
    dichloromethane 123.26
    cyclohexanone 123.38
    propylene glycol 85.39
    isopropyl acetate 68.61
    DMAc 178.29
    2-ethoxyethanol 123.1
    isopentanol 112.4
    n-heptane 12.45
    ethyl formate 69.84
    1,2-dichloroethane 61.11
    n-hexanol 141.36
    2-methoxyethanol 236.0
    isobutyl acetate 46.24
    tetrachloromethane 33.37
    n-pentyl acetate 56.86
    transcutol 271.36
    n-heptanol 79.88
    ethylbenzene 34.14
    MIBK 67.03
    2-propoxyethanol 200.25
    tert-butanol 225.78
    MTBE 117.48
    2-butoxyethanol 119.6
    propionic acid 80.16
    o-xylene 42.12
    formic acid 55.86
    diethyl ether 92.6
    m-xylene 42.78
    p-xylene 49.07
    chlorobenzene 49.9
    dimethyl carbonate 41.44
    n-octane 6.79
    formamide 86.1
    cyclopentanone 160.09
    2-pentanone 86.28
    anisole 82.65
    cyclopentyl methyl ether 101.99
    gamma-butyrolactone 156.23
    1-methoxy-2-propanol 195.59
    pyridine 114.1
    3-pentanone 59.89
    furfural 138.04
    n-dodecane 6.47
    diethylene glycol 148.48
    diisopropyl ether 34.78
    tert-amyl alcohol 132.44
    acetylacetone 93.37
    n-hexadecane 7.04
    acetophenone 68.23
    methyl propionate 77.69
    isopentyl acetate 81.81
    trichloroethylene 111.99
    n-nonanol 71.37
    cyclohexanol 82.26
    benzyl alcohol 68.09
    2-ethylhexanol 74.59
    isooctanol 61.61
    dipropyl ether 67.78
    1,2-dichlorobenzene 46.93
    ethyl lactate 41.57
    propylene carbonate 93.79
    n-methylformamide 103.35
    2-pentanol 87.23
    n-pentane 9.8
    1-propoxy-2-propanol 143.91
    1-methoxy-2-propyl acetate 101.25
    2-(2-methoxypropoxy) propanol 112.3
    mesitylene 31.51
    ε-caprolactone 111.76
    p-cymene 33.65
    epichlorohydrin 151.0
    1,1,1-trichloroethane 76.55
    2-aminoethanol 107.79
    morpholine-4-carbaldehyde 202.58
    sulfolane 147.34
    2,2,4-trimethylpentane 8.22
    2-methyltetrahydrofuran 169.75
    n-hexyl acetate 89.38
    isooctane 7.32
    2-(2-butoxyethoxy)ethanol 142.13
    sec-butyl acetate 45.62
    tert-butyl acetate 81.14
    decalin 10.52
    glycerin 98.6
    diglyme 218.31
    acrylic acid 60.78
    isopropyl myristate 44.35
    n-butyric acid 109.23
    acetyl acetate 64.04
    di(2-ethylhexyl) phthalate 46.67
    ethyl propionate 52.16
    nitromethane 130.47
    1,2-diethoxyethane 97.7
    benzonitrile 71.73
    trioctyl phosphate 37.92
    1-bromopropane 53.31
    gamma-valerolactone 209.17
    n-decanol 54.44
    triethyl phosphate 40.69
    4-methyl-2-pentanol 62.67
    propionitrile 98.84
    vinylene carbonate 87.86
    1,1,2-trichlorotrifluoroethane 108.56
    DMS 57.08
    cumene 29.87
    2-octanol 52.08
    2-hexanone 63.34
    octyl acetate 55.12
    limonene 44.85
    1,2-dimethoxyethane 200.7
    ethyl orthosilicate 41.99
    tributyl phosphate 40.61
    diacetone alcohol 108.67
    N,N-dimethylaniline 62.53
    acrylonitrile 96.71
    aniline 74.4
    1,3-propanediol 143.34
    bromobenzene 46.29
    dibromomethane 78.92
    1,1,2,2-tetrachloroethane 102.59
    2-methyl-cyclohexyl acetate 66.85
    tetrabutyl urea 49.86
    diisobutyl methanol 49.43
    2-phenylethanol 84.98
    styrene 36.68
    dioctyl adipate 56.13
    dimethyl sulfate 54.92
    ethyl butyrate 63.87
    methyl lactate 62.61
    butyl lactate 55.55
    diethyl carbonate 45.3
    propanediol butyl ether 108.02
    triethyl orthoformate 54.49
    p-tert-butyltoluene 35.96
    methyl 4-tert-butylbenzoate 80.35
    morpholine 281.5
    tert-butylamine 138.06
    n-dodecanol 41.43
    dimethoxymethane 146.9
    ethylene carbonate 76.68
    cyrene 92.39
    2-ethoxyethyl acetate 79.46
    2-ethylhexyl acetate 63.65
    1,2,4-trichlorobenzene 58.51
    4-methylpyridine 106.88
    dibutyl ether 57.39
    2,6-dimethyl-4-heptanol 49.43
    DEF 82.4
    dimethyl isosorbide 161.77
    tetrachloroethylene 67.37
    eugenol 79.08
    triacetin 79.68
    span 80 94.12
    1,4-butanediol 52.42
    1,1-dichloroethane 77.4
    2-methyl-1-pentanol 72.39
    methyl formate 75.92
    2-methyl-1-butanol 90.03
    n-decane 10.92
    butyronitrile 106.98
    3,7-dimethyl-1-octanol 72.15
    1-chlorooctane 35.7
    1-chlorotetradecane 16.11
    n-nonane 9.49
    undecane 8.11
    tert-butylcyclohexane 11.14
    cyclooctane 7.22
    cyclopentanol 101.89
    tetrahydropyran 177.84
    tert-amyl methyl ether 75.12
    2,5,8-trioxanonane 166.37
    1-hexene 28.12
    2-isopropoxyethanol 89.91
    2,2,2-trifluoroethanol 42.12
    methyl butyrate 63.17

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Nutmeg (India) 3 8008-45-5 Myristica fragrans Houtt., fam. Myristicaceae 0.01%