Muurolene(s) (CAS 69671-15-4) denotes a group of sesquiterpene hydrocarbons commonly found in essential oils (e.g., patchouli, myrrh, woody and balsamic resins) and is used primarily for: (1) perfumery—adding woody, earthy, resinous, warm-spicy facets with good substantivity due to low volatility; employed in fine fragrances, candles, personal care, and air care, typically as part of natural oils or their fractions; (2) flavoring at trace levels to deepen herbal/spicy and hop/beer notes in line with flavor-safety standards; (3) an analytical reference/marker in GC–MS for identification, standardization, and adulteration control of essential oils, and in phytochemistry, chemical ecology, and semiochemical research on plant volatiles (insect attractant/repellent roles), supporting cultivar screening and biobased agricultural applications; (4) a research target in pharmacognosy since related sesquiterpenes have reported in vitro/in vivo antimicrobial, anti-inflammatory, and antioxidant activities, suggesting potential for nature-derived cosmetic and skincare concepts (subject to toxicity, stability, and IFRA/REACH compliance); additionally, its occurrence profile aids traceability, quality assessment, and optimization of distillation/fractionation in the aroma industry.