Methyl Glycolate

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  • Identifiers

    CAS number
    96-35-5

    Molecular formula
    C3H6O3

    SMILES
    COC(=O)CO

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Caramellic 66.67%
    Ethereal 61.44%
    Winey 41.19%
    Buttery 40.54%
    Burnt 39.36%
    Sweet 39.15%
    Rummy 38.82%
    Fruity 35.71%
    Sharp 34.04%
    Sour 33.46%

    Scent© AI

  • Properties

    XLogP3-AA
    -0.5

    Molecular weight
    90.08 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point est.
    147°C

    Flash point est.
    64.45 ˚C

  • Synonyms

    • Methyl glycolate
    • methyl 2-hydroxyacetate
    • 96-35-5
    • Methyl hydroxyacetate
    • Acetic acid, hydroxy-, methyl ester
    • Glycolic acid, methyl ester
    • Hydroxyacetic Acid Methyl Ester
    • Acetic acid, 2-hydroxy-, methyl ester
    • Methyl 2-hydroxyethanoate
    • 2-hydroxyacetic acid methyl ester
    • EINECS 202-502-7
    • MFCD00004667
    • 7G7R729EJ0
    • NSC 27786
    • NSC-27786
    • Glycolic Acid Methyl Ester
    • UNII-7G7R729EJ0
    • DTXSID3059131
    • Methyl ester of hydroxyacetic acid
    • methyl2-hydroxyacetate
    • methyl2-hydroxyethanoate
    • Methyl glycolate, 98%
    • oxyacetic acid methyl ester
    • DTXCID4048981
    • hydroxy-acetic acid methyl ester
    • Acetic acid, hydroxy, methyl ester
    • NSC27786
    • STR00937
    • Glycolic acid, methyl ester (8CI)
    • Acetic acid, 2hydroxy, methyl ester
    • BBL009725
    • STL141090
    • AKOS005716966
    • CS-W004068
    • FM32897
    • SB83763
    • BP-13422
    • SY003097
    • DB-001049
    • G0199
    • NS00020244
    • EN300-42324
    • Q27894348
    • F0001-2294
    • 124238-96-6

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 87.55
    methanol 226.61
    isopropanol 42.36
    water 268.68
    ethyl acetate 14.12
    n-propanol 56.38
    acetone 48.67
    n-butanol 41.71
    acetonitrile 42.35
    DMF 291.01
    toluene 2.25
    isobutanol 33.01
    1,4-dioxane 59.34
    methyl acetate 26.67
    THF 63.1
    2-butanone 27.38
    n-pentanol 23.18
    sec-butanol 37.37
    n-hexane 1.34
    ethylene glycol 101.36
    NMP 190.95
    cyclohexane 3.1
    DMSO 476.21
    n-butyl acetate 5.17
    n-octanol 10.05
    chloroform 14.25
    n-propyl acetate 6.92
    acetic acid 188.22
    dichloromethane 29.78
    cyclohexanone 33.13
    propylene glycol 41.58
    isopropyl acetate 6.38
    DMAc 185.48
    2-ethoxyethanol 97.33
    isopentanol 27.51
    n-heptane 1.97
    ethyl formate 34.27
    1,2-dichloroethane 25.0
    n-hexanol 10.5
    2-methoxyethanol 198.93
    isobutyl acetate 2.9
    tetrachloromethane 5.37
    n-pentyl acetate 7.48
    transcutol 125.31
    n-heptanol 9.3
    ethylbenzene 1.84
    MIBK 9.2
    2-propoxyethanol 33.09
    tert-butanol 53.35
    MTBE 18.93
    2-butoxyethanol 26.13
    propionic acid 59.14
    o-xylene 4.43
    formic acid 463.54
    diethyl ether 17.87
    m-xylene 2.34
    p-xylene 2.75
    chlorobenzene 4.87
    dimethyl carbonate 10.88
    n-octane 1.08
    formamide 530.39
    cyclopentanone 45.22
    2-pentanone 17.85
    anisole 11.01
    cyclopentyl methyl ether 18.44
    gamma-butyrolactone 66.34
    1-methoxy-2-propanol 75.58
    pyridine 32.07
    3-pentanone 14.45
    furfural 104.02
    n-dodecane 0.82
    diethylene glycol 60.85
    diisopropyl ether 3.6
    tert-amyl alcohol 47.59
    acetylacetone 21.5
    n-hexadecane 0.86
    acetophenone 12.95
    methyl propionate 19.72
    isopentyl acetate 5.22
    trichloroethylene 31.19
    n-nonanol 8.93
    cyclohexanol 27.73
    benzyl alcohol 16.44
    2-ethylhexanol 6.62
    isooctanol 7.64
    dipropyl ether 6.65
    1,2-dichlorobenzene 7.13
    ethyl lactate 10.15
    propylene carbonate 20.27
    n-methylformamide 191.14
    2-pentanol 19.49
    n-pentane 2.26
    1-propoxy-2-propanol 17.28
    1-methoxy-2-propyl acetate 8.6
    2-(2-methoxypropoxy) propanol 31.91
    mesitylene 2.48
    ε-caprolactone 32.81
    p-cymene 2.83
    epichlorohydrin 62.64
    1,1,1-trichloroethane 8.11
    2-aminoethanol 116.36
    morpholine-4-carbaldehyde 149.77
    sulfolane 127.33
    2,2,4-trimethylpentane 1.62
    2-methyltetrahydrofuran 38.92
    n-hexyl acetate 9.76
    isooctane 0.79
    2-(2-butoxyethoxy)ethanol 41.98
    sec-butyl acetate 3.69
    tert-butyl acetate 8.89
    decalin 1.31
    glycerin 111.53
    diglyme 88.38
    acrylic acid 76.41
    isopropyl myristate 4.55
    n-butyric acid 42.16
    acetyl acetate 8.78
    di(2-ethylhexyl) phthalate 8.07
    ethyl propionate 7.24
    nitromethane 249.63
    1,2-diethoxyethane 20.0
    benzonitrile 12.29
    trioctyl phosphate 5.65
    1-bromopropane 8.25
    gamma-valerolactone 87.71
    n-decanol 6.49
    triethyl phosphate 6.64
    4-methyl-2-pentanol 9.44
    propionitrile 23.0
    vinylene carbonate 23.02
    1,1,2-trichlorotrifluoroethane 70.56
    DMS 8.89
    cumene 2.37
    2-octanol 6.38
    2-hexanone 8.5
    octyl acetate 6.24
    limonene 5.06
    1,2-dimethoxyethane 95.57
    ethyl orthosilicate 6.31
    tributyl phosphate 6.39
    diacetone alcohol 28.4
    N,N-dimethylaniline 12.31
    acrylonitrile 38.77
    aniline 15.07
    1,3-propanediol 115.33
    bromobenzene 2.95
    dibromomethane 14.49
    1,1,2,2-tetrachloroethane 23.68
    2-methyl-cyclohexyl acetate 6.93
    tetrabutyl urea 12.03
    diisobutyl methanol 5.37
    2-phenylethanol 8.95
    styrene 2.48
    dioctyl adipate 9.51
    dimethyl sulfate 35.75
    ethyl butyrate 6.67
    methyl lactate 23.75
    butyl lactate 10.78
    diethyl carbonate 5.14
    propanediol butyl ether 27.54
    triethyl orthoformate 6.96
    p-tert-butyltoluene 2.75
    methyl 4-tert-butylbenzoate 19.19
    morpholine 87.09
    tert-butylamine 25.82
    n-dodecanol 5.03
    dimethoxymethane 69.57
    ethylene carbonate 16.57
    cyrene 37.34
    2-ethoxyethyl acetate 13.44
    2-ethylhexyl acetate 4.02
    1,2,4-trichlorobenzene 8.96
    4-methylpyridine 21.19
    dibutyl ether 7.79
    2,6-dimethyl-4-heptanol 5.37
    DEF 52.37
    dimethyl isosorbide 43.23
    tetrachloroethylene 23.41
    eugenol 23.73
    triacetin 15.72
    span 80 23.07
    1,4-butanediol 47.56
    1,1-dichloroethane 9.4
    2-methyl-1-pentanol 18.05
    methyl formate 107.39
    2-methyl-1-butanol 30.11
    n-decane 1.3
    butyronitrile 20.06
    3,7-dimethyl-1-octanol 9.06
    1-chlorooctane 3.85
    1-chlorotetradecane 1.79
    n-nonane 1.26
    undecane 0.98
    tert-butylcyclohexane 1.06
    cyclooctane 1.14
    cyclopentanol 40.3
    tetrahydropyran 27.93
    tert-amyl methyl ether 18.39
    2,5,8-trioxanonane 71.58
    1-hexene 3.15
    2-isopropoxyethanol 35.77
    2,2,2-trifluoroethanol 96.34
    methyl butyrate 13.51

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction