Fluoroacetic acid

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  • Identifiers

    CAS number
    144-49-0

    Molecular formula
    C2H3FO2

    SMILES
    C(C(=O)O)F

    Safety labels

    Acute Toxic
    Acute Toxic

    Environmental Hazard
    Environmental

  • Odor profile

    Odorless 73.49%
    Sour 42.92%
    Cheesy 29.25%
    Sharp 23.82%
    Buttery 21.79%
    Caramellic 21.46%
    Milky 20.83%
    Savory 20.05%
    Meaty 18.96%
    Dairy 18.62%

    Scent© AI

  • Properties

    XLogP3-AA
    0.2

    Molecular weight
    78.04 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Melting point expt.

    • 95.4 °F (EPA, 1998)
    • 35.2 °C

    Boiling point

    • 329 °F at 760 mmHg (EPA, 1998)
    • 168 °C
    • 165 °C

    Flash point est.
    77.79 ˚C

    Solubility expt.

    • Miscible with water (1.0X10+6 mg/L) at 25 °C
    • Soluble in ethanol
    • Solubility in water: freely soluble

  • Synonyms

    • FLUOROACETIC ACID
    • 2-Fluoroacetic acid
    • 144-49-0
    • Cymonic acid
    • Gifblaar poison
    • Monofluoroacetic acid
    • Fluoroethanoic acid
    • Acetic acid, fluoro-
    • Monofluoressigsaure
    • Acetic acid, 2-fluoro-
    • Acide-monofluoracetique
    • Monofluorazijnzuur
    • Acido monofluoroacetio
    • Caswell No. 462
    • Monofluorazijnzuur [Dutch]
    • Acido monofluoracetio
    • Monofluoressigsaure [German]
    • Acido monofluoracetio [Italian]
    • Acide-monofluoracetique [French]
    • Acido monofluoroacetio [Italian]
    • HSDB 2082
    • UNII-AP1JV9U41M
    • EINECS 205-631-7
    • AP1JV9U41M
    • UN2642
    • EPA Pesticide Chemical Code 075001
    • UN 2642
    • BRN 1739053
    • MFA (Salt/Mix)
    • DTXSID0041981
    • HFA
    • CHEBI:30775
    • AI3-28547
    • CH2FCOOH
    • Monofluoroacetate
    • FLUOROACETIC ACID [MI]
    • DTXCID8021981
    • FLUOROACETIC ACID [HSDB]
    • 4-02-00-00446 (Beilstein Handbook Reference)
    • Monofluorazijnzuur (Dutch)
    • Monofluoressigsaure (German)
    • Alpha-fluoroacetic acid
    • Acido monofluoracetio (Italian)
    • Acide-monofluoracetique (French)
    • fluoroaceticacid
    • fluoro-acetic acid
    • 2Fluoroacetic acid
    • FAH
    • Acetic acid, fluoro
    • Acidemonofluoracetique
    • Fluoroacetate (FAC)
    • Spectrum_001872
    • SpecPlus_000915
    • Fluoroacetic acid, 95%
    • NCIOpen2_000661
    • KBioSS_002392
    • DivK1c_007011
    • CHEMBL509273
    • KBio1_001955
    • KBio2_002387
    • KBio2_004955
    • KBio2_007523
    • DTXSID30200339
    • Tox21_302429
    • MFCD00039529
    • AKOS006230216
    • FF77128
    • USEPA/OPP Pesticide Code: 075001
    • Fluoroacetic acid [UN2642] [Poison]
    • NCGC00255974-01
    • CAS-144-49-0
    • NS00008445
    • C06108
    • Q420215
    • 205-631-7

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 233.8
    methanol 581.24
    isopropanol 113.82
    water 2589.26
    ethyl acetate 11.97
    n-propanol 118.38
    acetone 126.09
    n-butanol 62.53
    acetonitrile 79.14
    DMF 1425.58
    toluene 2.25
    isobutanol 59.77
    1,4-dioxane 49.88
    methyl acetate 31.2
    THF 58.88
    2-butanone 42.86
    n-pentanol 33.95
    sec-butanol 55.21
    n-hexane 1.76
    ethylene glycol 463.88
    NMP 403.04
    cyclohexane 2.88
    DMSO 911.15
    n-butyl acetate 6.61
    n-octanol 9.89
    chloroform 4.19
    n-propyl acetate 11.49
    acetic acid 201.06
    dichloromethane 9.88
    cyclohexanone 31.99
    propylene glycol 234.23
    isopropyl acetate 6.58
    DMAc 567.44
    2-ethoxyethanol 166.45
    isopentanol 32.99
    n-heptane 3.09
    ethyl formate 43.79
    1,2-dichloroethane 12.57
    n-hexanol 15.25
    2-methoxyethanol 382.25
    isobutyl acetate 4.32
    tetrachloromethane 1.7
    n-pentyl acetate 5.06
    transcutol 106.1
    n-heptanol 9.96
    ethylbenzene 1.8
    MIBK 10.96
    2-propoxyethanol 63.04
    tert-butanol 94.02
    MTBE 17.26
    2-butoxyethanol 34.69
    propionic acid 87.52
    o-xylene 4.58
    formic acid 619.27
    diethyl ether 18.04
    m-xylene 2.85
    p-xylene 2.42
    chlorobenzene 1.38
    dimethyl carbonate 32.05
    n-octane 1.05
    formamide 723.29
    cyclopentanone 47.09
    2-pentanone 24.0
    anisole 8.93
    cyclopentyl methyl ether 18.77
    gamma-butyrolactone 61.08
    1-methoxy-2-propanol 169.46
    pyridine 21.19
    3-pentanone 20.24
    furfural 75.6
    n-dodecane 0.74
    diethylene glycol 120.62
    diisopropyl ether 4.29
    tert-amyl alcohol 55.09
    acetylacetone 23.73
    n-hexadecane 0.74
    acetophenone 12.89
    methyl propionate 28.95
    isopentyl acetate 4.4
    trichloroethylene 9.55
    n-nonanol 8.65
    cyclohexanol 27.12
    benzyl alcohol 17.37
    2-ethylhexanol 6.63
    isooctanol 7.08
    dipropyl ether 11.59
    1,2-dichlorobenzene 1.8
    ethyl lactate 22.14
    propylene carbonate 19.13
    n-methylformamide 593.4
    2-pentanol 26.1
    n-pentane 3.6
    1-propoxy-2-propanol 34.59
    1-methoxy-2-propyl acetate 11.36
    2-(2-methoxypropoxy) propanol 35.43
    mesitylene 2.72
    ε-caprolactone 27.5
    p-cymene 2.56
    epichlorohydrin 40.68
    1,1,1-trichloroethane 2.96
    2-aminoethanol 428.1
    morpholine-4-carbaldehyde 289.04
    sulfolane 115.12
    2,2,4-trimethylpentane 1.37
    2-methyltetrahydrofuran 24.13
    n-hexyl acetate 6.81
    isooctane 0.84
    2-(2-butoxyethoxy)ethanol 44.38
    sec-butyl acetate 4.42
    tert-butyl acetate 7.04
    decalin 0.96
    glycerin 353.68
    diglyme 88.34
    acrylic acid 116.41
    isopropyl myristate 2.88
    n-butyric acid 41.97
    acetyl acetate 6.41
    di(2-ethylhexyl) phthalate 5.45
    ethyl propionate 10.35
    nitromethane 274.66
    1,2-diethoxyethane 14.93
    benzonitrile 7.96
    trioctyl phosphate 4.33
    1-bromopropane 5.26
    gamma-valerolactone 109.24
    n-decanol 6.61
    triethyl phosphate 5.76
    4-methyl-2-pentanol 10.87
    propionitrile 35.43
    vinylene carbonate 22.83
    1,1,2-trichlorotrifluoroethane 63.89
    DMS 7.96
    cumene 1.97
    2-octanol 5.65
    2-hexanone 12.97
    octyl acetate 4.79
    limonene 4.14
    1,2-dimethoxyethane 147.44
    ethyl orthosilicate 5.43
    tributyl phosphate 4.54
    diacetone alcohol 30.64
    N,N-dimethylaniline 16.13
    acrylonitrile 64.37
    aniline 11.21
    1,3-propanediol 241.23
    bromobenzene 0.79
    dibromomethane 5.35
    1,1,2,2-tetrachloroethane 8.9
    2-methyl-cyclohexyl acetate 5.27
    tetrabutyl urea 13.72
    diisobutyl methanol 4.97
    2-phenylethanol 8.7
    styrene 1.96
    dioctyl adipate 6.24
    dimethyl sulfate 65.64
    ethyl butyrate 7.71
    methyl lactate 58.94
    butyl lactate 12.0
    diethyl carbonate 5.38
    propanediol butyl ether 42.8
    triethyl orthoformate 6.99
    p-tert-butyltoluene 2.57
    methyl 4-tert-butylbenzoate 14.0
    morpholine 108.12
    tert-butylamine 41.16
    n-dodecanol 5.27
    dimethoxymethane 180.08
    ethylene carbonate 16.97
    cyrene 54.92
    2-ethoxyethyl acetate 8.45
    2-ethylhexyl acetate 3.29
    1,2,4-trichlorobenzene 2.35
    4-methylpyridine 18.74
    dibutyl ether 5.77
    2,6-dimethyl-4-heptanol 4.97
    DEF 91.11
    dimethyl isosorbide 33.82
    tetrachloroethylene 7.07
    eugenol 21.93
    triacetin 11.72
    span 80 24.49
    1,4-butanediol 124.7
    1,1-dichloroethane 5.29
    2-methyl-1-pentanol 17.63
    methyl formate 283.21
    2-methyl-1-butanol 35.79
    n-decane 1.07
    butyronitrile 24.29
    3,7-dimethyl-1-octanol 6.76
    1-chlorooctane 2.04
    1-chlorotetradecane 1.15
    n-nonane 1.08
    undecane 0.85
    tert-butylcyclohexane 0.85
    cyclooctane 1.37
    cyclopentanol 42.39
    tetrahydropyran 20.67
    tert-amyl methyl ether 14.76
    2,5,8-trioxanonane 66.84
    1-hexene 3.83
    2-isopropoxyethanol 64.11
    2,2,2-trifluoroethanol 135.0
    methyl butyrate 19.0

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction