Dimethyl Sulfide

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  • Identifiers

    CAS number
    75-18-3

    Molecular formula
    C2H6S

    SMILES
    CSC

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

    Retention indicies (RI)

    • DB5: 505.0
    • Carbowax: 853.0

  • Odor profile

    Sulfurous 75.01%
    Vegetable 74.71%
    Green 63.99%
    Fruity 63.72%
    Onion 63.13%
    Sweet 59.62%
    Alliaceous 56.06%
    Cabbage 55.49%
    Garlic 55.24%
    Tomato 53.86%

    Scent© AI

    Odor threshold>

    • Odor Threshold Low: 0.0098 [mmHg]. Odor Threshold High: 0.02 [mmHg]. [ICSC] Odor threshold from CHEMINFO
    • The mean value of an odor threshold determined by sensory test for dimethyl sulfide was 0.063 ppm.
    • Reported odor threshold for dimethyl sulfide is 1-20 ppb, with a mean value of 11 ppb
    • Approx 1 ppb.

  • Properties

    XLogP3-AA
    0.9

    Molecular weight
    62.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -144 °F (USCG, 1999)
    • -98.24 °C
    • -98.3 °C
    • -98 °C
    • -144 °F

    Boiling point

    • 99 °F at 760 mmHg (USCG, 1999)
    • 37 °C
    • 37.3 °C
    • 37.30 °C. @ 760.00 mm Hg
    • 99 °F

    Flash point est.
    -32.8 ˚C

    Flash point expt.

    • -36 °F (USCG, 1999)
    • -48 °C (closed cup)
    • -49 °C
    • -36 °F

    Solubility expt.

    • Soluble in alcohol, ether; soluble in water at concentrations below 300 mM
    • Slightly soluble in water; soluble in ethanol, ethyl ether
    • In water, 2.2X10+4 mg/L at 25 °C
    • 22 mg/mL at 25 °C
    • Solubility in water: none
    • insoluble in water; soluble in ethyl alcohol and ethyl ether
    • 1 ml in 1 ml 95% alcohol (in ethanol)

  • Synonyms

    • dimethyl sulfide
    • Methyl sulfide
    • 75-18-3
    • Methane, thiobis-
    • dimethyl sulphide
    • dimethylsulfide
    • Methyl thioether
    • Dimethylsulphide
    • 2-Thiapropane
    • Dimethyl thioether
    • Methyl sulphide
    • Methylthiomethane
    • METHYLSULFANYLMETHANE
    • Dimethylsulfid
    • (Methylsulfanyl)methane
    • Methyl monosulfide
    • Thiobismethane
    • Dimethyl monosulfide
    • 2-Thiopropane
    • Methanethiomethane
    • Thiobis(methane)
    • Exact-S
    • Sulfure de methyle
    • Dimethyl sulfide (natural)
    • Dimethylsulfid [Czech]
    • FEMA No. 2746
    • Sulfure de methyle [French]
    • Methylsulphide
    • Methylthiomethyl radical
    • HSDB 356
    • Methane, 1,1'-thiobis-
    • [SMe2]
    • EINECS 200-846-2
    • QS3J7O7L3U
    • MFCD00008562
    • BRN 1696847
    • CHEBI:17437
    • AI3-25274
    • reduced dimethyl sulfoxide
    • DIMETHYL SULFIDE [MI]
    • METHYL SULFIDE [FHFI]
    • DIMETHYL SULFIDE [FCC]
    • DIMETHYL SULFIDE [HSDB]
    • DTXSID9026398
    • (CH3)2S
    • EC 200-846-2
    • 4-01-00-01275 (Beilstein Handbook Reference)
    • (SMe2)
    • 31533-72-9
    • methylsulfide
    • UN1164
    • UNII-QS3J7O7L3U
    • dimethylsulfane
    • Thiopropane
    • Thiobis-methane
    • 2Thiapropane
    • di-methylsulfide
    • ExactS
    • Dimethyl sulfane
    • methane, thiobis
    • Sulfide, methyl-
    • (methylthio)methane
    • Me2S
    • REDUCED-DMSO
    • SMe2
    • Dimethyl sulfide, 98%
    • (Methylsulfanyl)methane #
    • Dimethyl sulfide [UN1164] [Flammable liquid]
    • Dimethyl sulfide, anhydrous
    • Dimethyl sulfoxide(Reduced)
    • (Me)2S
    • Dimethyl sulfide, >=99%
    • CHEMBL15580
    • DTXCID106398
    • S(CH3)2
    • Dimethyl sulfide, >=99%, FCC
    • Dimethyl sulfide, analytical standard
    • STL481894
    • Dimethyl sulfide, >=95.0% (GC)
    • AKOS009031411
    • UN 1164
    • Dimethyl sulfide, anhydrous, >=99.0%
    • M0431
    • NS00005000
    • NS00124710
    • Dimethyl sulfide, puriss., >=99.0% (GC)
    • C00580
    • Dimethyl sulfide, natural, >=99%, FCC, FG
    • Dimethyl sulfide [UN1164] [Flammable liquid]
    • A838342
    • Dimethyl sulfide, redistilled, >=99%, FCC, FG
    • Q423133
    • 200-846-2

  • Applications

    Dimethyl sulfide (DMS, CAS 75-18-3) is an important solvent and synthetic intermediate: it is oxidized to dimethyl sulfoxide (DMSO) and dimethyl sulfone, serves as the main precursor for feed-grade methionine, imparts sweet corn, seafood and truffle notes to flavors, functions as an odorant for natural gas and LPG leak detection, acts as a coke-inhibiting additive during crude-oil distillation, supplies sulfur in agrochemical and pharmaceutical syntheses, works as an extracting solvent for metal sulfides, a reducing agent in analytical chemistry, a flavour modulator in beer and wine, and finds use in low-temperature battery electrolytes as well as atmospheric research to simulate cloud-forming processes.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 329.58
    methanol 302.01
    isopropanol 256.28
    water 2.65
    ethyl acetate 168.63
    n-propanol 280.45
    acetone 332.93
    n-butanol 276.92
    acetonitrile 160.69
    DMF 239.37
    toluene 136.53
    isobutanol 190.42
    1,4-dioxane 347.58
    methyl acetate 156.19
    THF 648.91
    2-butanone 245.45
    n-pentanol 150.39
    sec-butanol 229.96
    n-hexane 171.08
    ethylene glycol 104.17
    NMP 332.41
    cyclohexane 314.01
    DMSO 285.36
    n-butyl acetate 289.59
    n-octanol 168.29
    chloroform 469.1
    n-propyl acetate 126.47
    acetic acid 326.54
    dichloromethane 297.71
    cyclohexanone 427.73
    propylene glycol 154.57
    isopropyl acetate 114.05
    DMAc 177.44
    2-ethoxyethanol 161.61
    isopentanol 177.73
    n-heptane 350.8
    ethyl formate 104.9
    1,2-dichloroethane 183.13
    n-hexanol 352.38
    2-methoxyethanol 293.89
    isobutyl acetate 96.25
    tetrachloromethane 165.15
    n-pentyl acetate 147.25
    transcutol 423.69
    n-heptanol 196.56
    ethylbenzene 70.41
    MIBK 109.18
    2-propoxyethanol 353.29
    tert-butanol 269.41
    MTBE 183.09
    2-butoxyethanol 222.28
    propionic acid 247.15
    o-xylene 96.18
    formic acid 88.24
    diethyl ether 236.39
    m-xylene 89.86
    p-xylene 92.06
    chlorobenzene 149.69
    dimethyl carbonate 62.22
    n-octane 85.09
    formamide 89.36
    cyclopentanone 499.36
    2-pentanone 209.59
    anisole 112.81
    cyclopentyl methyl ether 340.46
    gamma-butyrolactone 383.05
    1-methoxy-2-propanol 246.2
    pyridine 272.05
    3-pentanone 181.32
    furfural 269.62
    n-dodecane 43.68
    diethylene glycol 213.65
    diisopropyl ether 96.23
    tert-amyl alcohol 212.98
    acetylacetone 174.1
    n-hexadecane 47.15
    acetophenone 101.81
    methyl propionate 144.92
    isopentyl acetate 205.38
    trichloroethylene 318.02
    n-nonanol 149.08
    cyclohexanol 314.38
    benzyl alcohol 95.44
    2-ethylhexanol 262.35
    isooctanol 140.22
    dipropyl ether 381.59
    1,2-dichlorobenzene 125.27
    ethyl lactate 75.89
    propylene carbonate 209.68
    n-methylformamide 138.48
    2-pentanol 195.99
    n-pentane 172.72
    1-propoxy-2-propanol 381.2
    1-methoxy-2-propyl acetate 179.96
    2-(2-methoxypropoxy) propanol 146.11
    mesitylene 65.91
    ε-caprolactone 289.73
    p-cymene 114.05
    epichlorohydrin 264.32
    1,1,1-trichloroethane 243.17
    2-aminoethanol 178.03
    morpholine-4-carbaldehyde 273.88
    sulfolane 397.19
    2,2,4-trimethylpentane 52.26
    2-methyltetrahydrofuran 424.83
    n-hexyl acetate 190.12
    isooctane 42.14
    2-(2-butoxyethoxy)ethanol 219.8
    sec-butyl acetate 84.68
    tert-butyl acetate 132.07
    decalin 75.57
    glycerin 177.16
    diglyme 341.54
    acrylic acid 204.36
    isopropyl myristate 93.64
    n-butyric acid 283.86
    acetyl acetate 116.96
    di(2-ethylhexyl) phthalate 74.7
    ethyl propionate 109.54
    nitromethane 228.91
    1,2-diethoxyethane 210.84
    benzonitrile 128.15
    trioctyl phosphate 70.91
    1-bromopropane 197.42
    gamma-valerolactone 398.3
    n-decanol 113.47
    triethyl phosphate 81.71
    4-methyl-2-pentanol 95.68
    propionitrile 167.09
    vinylene carbonate 162.79
    1,1,2-trichlorotrifluoroethane 255.84
    DMS 93.03
    cumene 56.84
    2-octanol 128.23
    2-hexanone 163.34
    octyl acetate 120.69
    limonene 212.76
    1,2-dimethoxyethane 232.36
    ethyl orthosilicate 90.29
    tributyl phosphate 78.26
    diacetone alcohol 167.55
    N,N-dimethylaniline 88.09
    acrylonitrile 160.82
    aniline 156.12
    1,3-propanediol 210.16
    bromobenzene 147.6
    dibromomethane 269.02
    1,1,2,2-tetrachloroethane 290.44
    2-methyl-cyclohexyl acetate 162.37
    tetrabutyl urea 105.44
    diisobutyl methanol 154.0
    2-phenylethanol 150.96
    styrene 85.58
    dioctyl adipate 114.65
    dimethyl sulfate 79.2
    ethyl butyrate 198.07
    methyl lactate 95.01
    butyl lactate 132.04
    diethyl carbonate 110.44
    propanediol butyl ether 190.76
    triethyl orthoformate 154.33
    p-tert-butyltoluene 113.7
    methyl 4-tert-butylbenzoate 124.66
    morpholine 383.93
    tert-butylamine 216.95
    n-dodecanol 94.52
    dimethoxymethane 165.2
    ethylene carbonate 151.24
    cyrene 115.65
    2-ethoxyethyl acetate 136.64
    2-ethylhexyl acetate 190.68
    1,2,4-trichlorobenzene 148.34
    4-methylpyridine 205.82
    dibutyl ether 226.91
    2,6-dimethyl-4-heptanol 154.0
    DEF 176.94
    dimethyl isosorbide 209.59
    tetrachloroethylene 247.04
    eugenol 119.95
    triacetin 142.21
    span 80 207.08
    1,4-butanediol 87.15
    1,1-dichloroethane 223.8
    2-methyl-1-pentanol 110.3
    methyl formate 101.98
    2-methyl-1-butanol 171.99
    n-decane 76.1
    butyronitrile 185.86
    3,7-dimethyl-1-octanol 141.5
    1-chlorooctane 130.96
    1-chlorotetradecane 60.31
    n-nonane 86.96
    undecane 53.68
    tert-butylcyclohexane 69.29
    cyclooctane 123.81
    cyclopentanol 338.7
    tetrahydropyran 481.96
    tert-amyl methyl ether 159.2
    2,5,8-trioxanonane 240.43
    1-hexene 215.75
    2-isopropoxyethanol 124.11
    2,2,2-trifluoroethanol 108.71
    methyl butyrate 139.96

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Onion 8002-72-0 Allium cepa L., fam. Liliaceae 1.1%
Truffle, black (Perigord) Tuber melanosporum, fam. Ascomycetae 7.5%
Celery plant 8015-90-5 Apium graveolens L. var. dulce, fam. Apiaceae (Umbelliferae) 0.01%
Geranium 2 8000-46-2 Pelargonium graveolens L'Herit. ex Aiton, fam. Geraniaceae 0.03%
Coriander fruit 5 8008-52-4 Coriandrum sativum L., fam. Apiaceae (Umbelliferae) 0.01%
Niaouli (India) Melaleuca quinquenervia (Cav.) S.T. Blake, fam. Myrtaceae 0.05%