Cyclohexanol

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  • Identifiers

    CAS number
    108-93-0

    Molecular formula
    C6H12O

    SMILES
    C1CCC(CC1)O

    Safety labels

    Irritant
    Irritant

    Retention indicies (RI)

    • DB5: 880.0
    • Carbowax: 1392.5

  • Odor profile

    Fermented 64.53%
    Solvent 62.05%
    Mint 55.15%
    Alcoholic 51.33%
    Ethereal 51.3%
    Camphoreous 49.8%
    Musty 40.03%
    Oily 37.18%
    Phenolic 31.39%
    Fruity 29.64%

    Scent© AI

    Odor threshold>

    • Odor Threshold Low: 0.05 [mmHg]. Odor Threshold High: 0.15 [mmHg]. Detection odor threshold from AIHA (mean = 0.16 ppm)
    • 0.07 ppm

  • Properties

    XLogP3-AA
    1.2

    Molecular weight
    100.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Melting point expt.

    • 73 °F (NTP, 1992)
    • 25.4 °C
    • 25.93 °C
    • 23 °C
    • 77 °F

    Boiling point

    • 322 °F at 760 mmHg (NTP, 1992)
    • 160.8 °C
    • 161.84 °C
    • 161 °C
    • 322 °F

    Flash point est.
    59.22 ˚C

    Flash point expt.

    • 154 °F (NTP, 1992)
    • 63 °C
    • 62.8 °C (closed cup); 67.8 °C (open cup)
    • 68 °C c.c.
    • 154 °F

    Solubility expt.

    • Soluble (NTP, 1992)
    • 42000 mg/L (at 10 °C)
    • 3.6% (wt/wt) in water at 20 °C; miscible with ethyl acetate, linseed oil, petroleum solvents.
    • Soluble in ethanol, ethyl ether, acetone; miscible with benzene; slightly soluble in chloroform
    • In water, 4.3 g/100 g (4.3X10+4 mg/L) at 30 °C; 4.2 g/100 g (4.2X10+4 mg/L) at 10 °C
    • Solubility in water, g/100ml at 20 °C: 4
    • 4%

  • Synonyms

    • CYCLOHEXANOL
    • 108-93-0
    • Cyclohexyl alcohol
    • 1-Cyclohexanol
    • Hexahydrophenol
    • Hydrophenol
    • Hydroxycyclohexane
    • Hexalin
    • Adronal
    • Hydralin
    • Naxol
    • Adronol
    • Anol
    • Cicloesanolo
    • Cykloheksanol
    • Phenol, hexahydro-
    • Cicloesanolo [Italian]
    • Cykloheksanol [Polish]
    • Cyclohexan-1-ol
    • HSDB 61
    • CCRIS 5896
    • NSC 403656
    • cyclohexyl-alcohol
    • EINECS 203-630-6
    • MFCD00003855
    • UNII-8E7S519M3P
    • BRN 0906744
    • DTXSID4021894
    • CHEBI:18099
    • AI3-00040
    • 8E7S519M3P
    • NSC-403656
    • DTXCID001894
    • EC 203-630-6
    • 4-06-00-00020 (Beilstein Handbook Reference)
    • Cyclohexanol-d11
    • CXL
    • Cyclohexanols
    • Ciclohexanol
    • Hydroxycyclohexane; NSC 403656; NSC 54711; Naxol; Phenol, hexahydro-
    • CAS-108-93-0
    • Cylcohexanol
    • Cyclohexane, hydroxy-
    • BDBM5
    • CYCLOHEXANOL [MI]
    • HEXALIN (ALCOHOL)
    • bmse000431
    • WLN: L6TJ AQ
    • CYCLOHEXANOL [HSDB]
    • SCHEMBL5545
    • MLS001055343
    • BIDD:ER0291
    • CHEMBL32010
    • Cyclohexanol, p.a., 99.0%
    • Cyclohexanol, analytical standard
    • HMS3039K08
    • HY-Y1217
    • TDA13117
    • Tox21_201481
    • Tox21_302803
    • BBL013186
    • Cyclohexanol, ReagentPlus(R), 99%
    • NSC403656
    • STL163965
    • AKOS000119038
    • DB03703
    • RP10050
    • NCGC00090982-01
    • NCGC00090982-02
    • NCGC00256434-01
    • NCGC00259032-01
    • SMR000677941
    • Cyclohexanol, puriss., >=99.0% (GC)
    • Cyclohexanol, SAJ first grade, >=95.0%
    • DB-040851
    • CS-0017198
    • Cyclohexanol, JIS special grade, >=98.0%
    • NS00010075
    • Cyclohexanol, Vetec(TM) reagent grade, 98%
    • EN300-19310
    • C00854
    • Q423282
    • F0001-0184
    • Z104473498
    • 203-630-6

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 961.17
    methanol 1003.4
    isopropanol 673.07
    water 1.69
    ethyl acetate 402.68
    n-propanol 736.75
    acetone 466.87
    n-butanol 711.19
    acetonitrile 335.46
    DMF 288.58
    toluene 78.82
    isobutanol 401.22
    1,4-dioxane 568.77
    methyl acetate 285.29
    THF 1119.24
    2-butanone 372.52
    n-pentanol 384.02
    sec-butanol 460.83
    n-hexane 106.74
    ethylene glycol 108.81
    NMP 333.33
    cyclohexane 100.03
    DMSO 459.57
    n-butyl acetate 515.96
    n-octanol 167.72
    chloroform 999.05
    n-propyl acetate 258.81
    acetic acid 621.56
    dichloromethane 601.22
    cyclohexanone 502.94
    propylene glycol 175.5
    isopropyl acetate 210.94
    DMAc 146.99
    2-ethoxyethanol 328.28
    isopentanol 433.35
    n-heptane 118.5
    ethyl formate 289.86
    1,2-dichloroethane 319.66
    n-hexanol 535.74
    2-methoxyethanol 655.59
    isobutyl acetate 141.31
    tetrachloromethane 179.58
    n-pentyl acetate 239.62
    transcutol 1058.73
    n-heptanol 218.26
    ethylbenzene 42.78
    MIBK 169.42
    2-propoxyethanol 571.52
    tert-butanol 528.54
    MTBE 265.03
    2-butoxyethanol 326.28
    propionic acid 515.63
    o-xylene 51.67
    formic acid 192.62
    diethyl ether 457.91
    m-xylene 57.32
    p-xylene 61.92
    chlorobenzene 171.64
    dimethyl carbonate 45.48
    n-octane 34.42
    formamide 204.3
    cyclopentanone 616.89
    2-pentanone 348.01
    anisole 96.85
    cyclopentyl methyl ether 364.77
    gamma-butyrolactone 712.93
    1-methoxy-2-propanol 444.49
    pyridine 423.83
    3-pentanone 191.88
    furfural 468.53
    n-dodecane 18.97
    diethylene glycol 328.55
    diisopropyl ether 103.22
    tert-amyl alcohol 325.05
    acetylacetone 220.31
    n-hexadecane 20.75
    acetophenone 92.95
    methyl propionate 218.46
    isopentyl acetate 319.32
    trichloroethylene 581.44
    n-nonanol 151.76
    cyclohexanol 352.16
    benzyl alcohol 107.31
    2-ethylhexanol 272.46
    isooctanol 160.4
    dipropyl ether 396.06
    1,2-dichlorobenzene 136.93
    ethyl lactate 95.13
    propylene carbonate 372.93
    n-methylformamide 327.6
    2-pentanol 371.42
    n-pentane 103.99
    1-propoxy-2-propanol 501.23
    1-methoxy-2-propyl acetate 257.42
    2-(2-methoxypropoxy) propanol 178.57
    mesitylene 39.72
    ε-caprolactone 465.0
    p-cymene 59.91
    epichlorohydrin 525.18
    1,1,1-trichloroethane 337.87
    2-aminoethanol 324.58
    morpholine-4-carbaldehyde 327.02
    sulfolane 514.73
    2,2,4-trimethylpentane 31.98
    2-methyltetrahydrofuran 685.29
    n-hexyl acetate 250.49
    isooctane 29.68
    2-(2-butoxyethoxy)ethanol 336.05
    sec-butyl acetate 135.04
    tert-butyl acetate 185.93
    decalin 31.94
    glycerin 214.42
    diglyme 502.02
    acrylic acid 347.29
    isopropyl myristate 92.34
    n-butyric acid 818.47
    acetyl acetate 174.13
    di(2-ethylhexyl) phthalate 71.52
    ethyl propionate 171.65
    nitromethane 600.82
    1,2-diethoxyethane 440.29
    benzonitrile 200.71
    trioctyl phosphate 65.26
    1-bromopropane 320.96
    gamma-valerolactone 639.05
    n-decanol 107.07
    triethyl phosphate 77.09
    4-methyl-2-pentanol 163.72
    propionitrile 355.21
    vinylene carbonate 284.1
    1,1,2-trichlorotrifluoroethane 366.11
    DMS 101.41
    cumene 37.04
    2-octanol 135.96
    2-hexanone 247.96
    octyl acetate 116.04
    limonene 107.75
    1,2-dimethoxyethane 408.13
    ethyl orthosilicate 83.55
    tributyl phosphate 86.78
    diacetone alcohol 212.65
    N,N-dimethylaniline 60.04
    acrylonitrile 340.6
    aniline 174.67
    1,3-propanediol 475.06
    bromobenzene 143.78
    dibromomethane 472.53
    1,1,2,2-tetrachloroethane 510.37
    2-methyl-cyclohexyl acetate 153.42
    tetrabutyl urea 93.41
    diisobutyl methanol 145.49
    2-phenylethanol 165.04
    styrene 56.06
    dioctyl adipate 111.26
    dimethyl sulfate 64.0
    ethyl butyrate 301.85
    methyl lactate 107.11
    butyl lactate 175.25
    diethyl carbonate 139.81
    propanediol butyl ether 238.04
    triethyl orthoformate 182.74
    p-tert-butyltoluene 56.49
    methyl 4-tert-butylbenzoate 109.26
    morpholine 703.01
    tert-butylamine 366.05
    n-dodecanol 79.15
    dimethoxymethane 211.81
    ethylene carbonate 262.82
    cyrene 110.76
    2-ethoxyethyl acetate 227.16
    2-ethylhexyl acetate 246.56
    1,2,4-trichlorobenzene 149.75
    4-methylpyridine 266.88
    dibutyl ether 263.59
    2,6-dimethyl-4-heptanol 145.49
    DEF 273.32
    dimethyl isosorbide 253.79
    tetrachloroethylene 405.33
    eugenol 118.21
    triacetin 158.15
    span 80 210.36
    1,4-butanediol 136.22
    1,1-dichloroethane 399.96
    2-methyl-1-pentanol 220.21
    methyl formate 179.32
    2-methyl-1-butanol 355.58
    n-decane 37.9
    butyronitrile 467.67
    3,7-dimethyl-1-octanol 169.13
    1-chlorooctane 109.01
    1-chlorotetradecane 36.93
    n-nonane 40.03
    undecane 25.36
    tert-butylcyclohexane 35.02
    cyclooctane 33.03
    cyclopentanol 446.93
    tetrahydropyran 724.97
    tert-amyl methyl ether 168.21
    2,5,8-trioxanonane 300.97
    1-hexene 265.25
    2-isopropoxyethanol 205.16
    2,2,2-trifluoroethanol 164.54
    methyl butyrate 247.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Michelia alba leaf (China) Michelia alba DC., fam. Magnoliaceae 0.26%
Helichrysum litoreum (Italy) 1a flower Helichrysum litoreum Guss., fam. Asteraceae (Compositae) 0.05%
Helichrysum litoreum (Italy) 1b stem Helichrysum litoreum Guss., fam. Asteraceae (Compositae) 0.05%
Banana passa headspace extract (Brazil) 89957-82-4 Musa cavendishii cultivar nanica, fam. Musaceae 0.3%
Ambarella fruit (Brazil) Spondias cytherea Sonnerat, fam. Anarcardiaceae 0.35%