3,5-Diethyl-2-methylpyrazine

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  • Identifiers

    CAS number
    18138-05-1

    Molecular formula
    C9H14N2

    SMILES
    CCC1=CN=C(C(=N1)CC)C

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Nutty 82.64%
    Roasted 75.37%
    Earthy 67.23%
    Cocoa 63.37%
    Hazelnut 59.36%
    Musty 57.88%
    Potato 56.34%
    Burnt 52.58%
    Coffee 51.25%
    Green 50.3%

    Scent© AI

  • Properties

    XLogP3-AA
    1.8

    Molecular weight
    150.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point

    • 95.00 °C. @ 14.00 mm Hg

    Flash point est.
    76.03 ˚C

    Solubility expt.

    • slightly
    • slightly soluble in water; soluble in oils, organic solvents
    • miscible at room temperature (in ethanol)

  • Synonyms

    • 3,5-DIETHYL-2-METHYLPYRAZINE
    • 18138-05-1
    • 3,5-diethyl-2-methyl pyrazine
    • 2-Methyl-3,5-diethylpyrazine
    • Pyrazine, 3,5-diethyl-2-methyl-
    • 2,6-Diethyl-3-methylpyrazine
    • UNII-7JG7NP41LF
    • 7JG7NP41LF
    • 2,6-Diethyl-5-methylpyrazine
    • 3,5-DIETHYL-2-METHYL-PYRAZINE
    • FEMA NO. 3916
    • FEMA 3916
    • DTXSID70171130
    • Pyrazine, 3,5-diethyl-2-methyl- (8CI,9CI)
    • 3,5-DIETHYL-5-METHYLPYRAZINE
    • 2-METHYL-3,5-DIETHYL-1,4-DIAZINE
    • 3,5-DIETHYL-2-METHYLPYRAZINE [FHFI]
    • SCHEMBL293166
    • DTXCID6093621
    • CHEBI:193680
    • AKOS006291469
    • DB-117077
    • NS00123564
    • G63470
    • Q27268410
    • 639-034-1

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 564.49
    methanol 596.43
    isopropanol 417.21
    water 2.34
    ethyl acetate 649.6
    n-propanol 538.13
    acetone 766.48
    n-butanol 492.91
    acetonitrile 707.53
    DMF 943.72
    toluene 617.79
    isobutanol 436.4
    1,4-dioxane 980.0
    methyl acetate 622.94
    THF 1227.23
    2-butanone 758.05
    n-pentanol 461.29
    sec-butanol 494.01
    n-hexane 239.23
    ethylene glycol 98.44
    NMP 979.31
    cyclohexane 345.81
    DMSO 764.04
    n-butyl acetate 993.34
    n-octanol 402.07
    chloroform 3714.1
    n-propyl acetate 553.15
    acetic acid 554.59
    dichloromethane 3669.63
    cyclohexanone 1255.45
    propylene glycol 128.99
    isopropyl acetate 393.46
    DMAc 771.11
    2-ethoxyethanol 442.24
    isopentanol 415.09
    n-heptane 219.35
    ethyl formate 713.85
    1,2-dichloroethane 1723.25
    n-hexanol 592.72
    2-methoxyethanol 589.26
    isobutyl acetate 385.69
    tetrachloromethane 910.34
    n-pentyl acetate 581.21
    transcutol 876.66
    n-heptanol 358.46
    ethylbenzene 446.16
    MIBK 355.34
    2-propoxyethanol 552.98
    tert-butanol 438.65
    MTBE 495.6
    2-butoxyethanol 423.67
    propionic acid 479.13
    o-xylene 428.32
    formic acid 164.11
    diethyl ether 625.85
    m-xylene 404.94
    p-xylene 662.77
    chlorobenzene 1148.28
    dimethyl carbonate 281.45
    n-octane 122.51
    formamide 242.24
    cyclopentanone 1231.28
    2-pentanone 600.37
    anisole 529.54
    cyclopentyl methyl ether 668.18
    gamma-butyrolactone 1388.46
    1-methoxy-2-propanol 398.61
    pyridine 1330.41
    3-pentanone 541.21
    furfural 1338.39
    n-dodecane 97.84
    diethylene glycol 290.73
    diisopropyl ether 212.91
    tert-amyl alcohol 457.48
    acetylacetone 605.36
    n-hexadecane 110.34
    acetophenone 533.87
    methyl propionate 514.49
    isopentyl acetate 737.75
    trichloroethylene 3210.92
    n-nonanol 322.42
    cyclohexanol 521.58
    benzyl alcohol 445.23
    2-ethylhexanol 456.04
    isooctanol 282.12
    dipropyl ether 508.15
    1,2-dichlorobenzene 1096.14
    ethyl lactate 232.72
    propylene carbonate 924.14
    n-methylformamide 537.32
    2-pentanol 344.55
    n-pentane 190.81
    1-propoxy-2-propanol 442.09
    1-methoxy-2-propyl acetate 489.92
    2-(2-methoxypropoxy) propanol 329.92
    mesitylene 300.13
    ε-caprolactone 965.35
    p-cymene 378.75
    epichlorohydrin 1487.47
    1,1,1-trichloroethane 1778.66
    2-aminoethanol 205.0
    morpholine-4-carbaldehyde 839.2
    sulfolane 1373.31
    2,2,4-trimethylpentane 113.41
    2-methyltetrahydrofuran 999.65
    n-hexyl acetate 712.07
    isooctane 75.41
    2-(2-butoxyethoxy)ethanol 415.59
    sec-butyl acetate 341.23
    tert-butyl acetate 362.82
    decalin 173.4
    glycerin 154.52
    diglyme 795.37
    acrylic acid 415.88
    isopropyl myristate 294.41
    n-butyric acid 691.86
    acetyl acetate 461.37
    di(2-ethylhexyl) phthalate 264.79
    ethyl propionate 473.76
    nitromethane 813.37
    1,2-diethoxyethane 617.96
    benzonitrile 939.85
    trioctyl phosphate 213.79
    1-bromopropane 1111.14
    gamma-valerolactone 1233.5
    n-decanol 246.76
    triethyl phosphate 298.87
    4-methyl-2-pentanol 199.37
    propionitrile 689.62
    vinylene carbonate 990.49
    1,1,2-trichlorotrifluoroethane 813.22
    DMS 466.09
    cumene 329.98
    2-octanol 304.17
    2-hexanone 567.08
    octyl acetate 372.52
    limonene 484.52
    1,2-dimethoxyethane 858.82
    ethyl orthosilicate 279.04
    tributyl phosphate 271.8
    diacetone alcohol 317.68
    N,N-dimethylaniline 423.34
    acrylonitrile 838.31
    aniline 553.73
    1,3-propanediol 316.46
    bromobenzene 1446.49
    dibromomethane 2462.43
    1,1,2,2-tetrachloroethane 2315.7
    2-methyl-cyclohexyl acetate 456.37
    tetrabutyl urea 332.39
    diisobutyl methanol 226.01
    2-phenylethanol 514.21
    styrene 564.48
    dioctyl adipate 384.06
    dimethyl sulfate 377.7
    ethyl butyrate 635.66
    methyl lactate 215.47
    butyl lactate 357.7
    diethyl carbonate 475.86
    propanediol butyl ether 340.7
    triethyl orthoformate 413.05
    p-tert-butyltoluene 317.99
    methyl 4-tert-butylbenzoate 433.22
    morpholine 902.92
    tert-butylamine 367.03
    n-dodecanol 201.59
    dimethoxymethane 623.28
    ethylene carbonate 804.24
    cyrene 328.43
    2-ethoxyethyl acetate 553.75
    2-ethylhexyl acetate 651.31
    1,2,4-trichlorobenzene 1093.69
    4-methylpyridine 1243.71
    dibutyl ether 568.97
    2,6-dimethyl-4-heptanol 226.01
    DEF 712.29
    dimethyl isosorbide 603.65
    tetrachloroethylene 1762.92
    eugenol 418.48
    triacetin 471.41
    span 80 340.97
    1,4-butanediol 190.04
    1,1-dichloroethane 1693.32
    2-methyl-1-pentanol 413.35
    methyl formate 530.04
    2-methyl-1-butanol 447.61
    n-decane 154.96
    butyronitrile 862.15
    3,7-dimethyl-1-octanol 326.12
    1-chlorooctane 449.85
    1-chlorotetradecane 194.68
    n-nonane 166.61
    undecane 118.22
    tert-butylcyclohexane 154.01
    cyclooctane 133.36
    cyclopentanol 581.5
    tetrahydropyran 1033.58
    tert-amyl methyl ether 406.17
    2,5,8-trioxanonane 527.31
    1-hexene 525.05
    2-isopropoxyethanol 312.63
    2,2,2-trifluoroethanol 208.68
    methyl butyrate 674.95

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction