2,4,6-Trimethylpyridine

Overview IFRA Request a quote

  • Identifiers

    CAS number
    108-75-8

    Molecular formula
    C8H11N

    SMILES
    CC1=CC(=NC(=C1)C)C

    Safety labels

    Flammable
    Flammable

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

  • Odor profile

    Green 79.18%
    Animal 51.79%
    Earthy 49.74%
    Fishy 49.03%
    Nutty 48.57%
    Musty 45.81%
    Woody 42.41%
    Leathery 40.16%
    Roasted 39.33%
    Herbal 38.97%

    Scent© AI

  • Properties

    XLogP3-AA
    1.9

    Molecular weight
    121.18 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Melting point expt.

    • -44.5 °C

    Boiling point

    • 170.4 °C

    Flash point est.
    50.81 ˚C

    Flash point expt.

    • 58 °C
    • 136 °F

    Solubility expt.

    • Sol in methanol, ethanol, chloroform, benzene, toluene, and dil acids; miscible with ether
    • Sol in acetone
    • Sol in water (in g/100 ml water): 20.8 g @ 6 °C, 3.5 g @ 20 °C, 1.8 g @ 100 °C

  • Synonyms

    • 2,4,6-Trimethylpyridine
    • 108-75-8
    • 2,4,6-COLLIDINE
    • s-Collidine
    • gamma-Collidine
    • Pyridine, 2,4,6-trimethyl-
    • COLLIDINE
    • sym-Collidine
    • .gamma.-Collidine
    • 2,4,6-trimethyl-pyridine
    • 2,4,6-Kollidin
    • HSDB 57
    • NSC 460
    • UNII-7IE4BK5J5V
    • 2,4,6-trimethyl pyridine
    • EINECS 203-613-3
    • MFCD00006338
    • BRN 0107283
    • AI3-10050
    • NSC-460
    • .alpha.,.gamma.,.alpha.'-Collidine
    • 7IE4BK5J5V
    • CHEMBL1209580
    • DTXSID1051561
    • 2,4,6-COLLIDINE [HSDB]
    • 5-20-06-00093 (Beilstein Handbook Reference)
    • 2,4,6-TRIMETHYLPYRIDINE [MI]
    • 2,4,6-Collidine (2,4,6-Trimethylpyridine)
    • 2,4,6-Kollidin [Czech]
    • alpha,gamma,alpha'-Collidine
    • 2,4,6 Trimethylpyridine
    • collidin
    • 2,4,6 COLLIDINE
    • gammaCollidine
    • sCollidine
    • 2,4,6Kollidin
    • 2,4,6-collidin
    • 2,4,6-Collinine
    • 2,4,6- collidine
    • 2,4,6trimethylpyridine
    • 2,4,6-trimethypyridine
    • Pyridine,4,6-trimethyl-
    • 2,4,6-tri-methylpyridine
    • alpha,gamma,alpha'Collidine
    • 2,4,6-Trimethylpyridinium
    • Pyridine, 2,4,6trimethyl
    • SCHEMBL7489
    • NCIOpen2_009389
    • pyridine, 2,4,6-trimethyl
    • .alpha.,.alpha.'-Collidine
    • 2,4,6-Collidine;s-Collidine
    • NSC460
    • DTXCID5030113
    • CHEBI:189131
    • STR03652
    • BDBM50416505
    • STL146741
    • AKOS000119121
    • CS-W018506
    • PS-5252
    • SB52289
    • BP-30156
    • DB-015912
    • NS00014381
    • T0716
    • 2,4,6-Trimethylpyridine, >=98.0% (GC)
    • EN300-19114
    • D77846
    • 2,4,6-Trimethylpyridine, ReagentPlus(R), 99%
    • Q409155
    • 2,4,6-Trimethylpyridine, Vetec(TM) reagent grade, 98%
    • F0001-0178
    • Z104472822
    • 2,4,6-Trimethylpyridine, puriss. p.a., >=99.0% (GC)
    • 203-613-3

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1121.4
    methanol 1278.36
    isopropanol 645.29
    water 14.11
    ethyl acetate 975.96
    n-propanol 872.14
    acetone 1002.87
    n-butanol 866.18
    acetonitrile 871.69
    DMF 641.41
    toluene 673.91
    isobutanol 608.33
    1,4-dioxane 1660.24
    methyl acetate 871.07
    THF 2339.04
    2-butanone 839.76
    n-pentanol 533.32
    sec-butanol 665.7
    n-hexane 561.09
    ethylene glycol 218.82
    NMP 1021.9
    cyclohexane 645.98
    DMSO 633.81
    n-butyl acetate 715.61
    n-octanol 383.25
    chloroform 1517.02
    n-propyl acetate 391.94
    acetic acid 864.49
    dichloromethane 1478.89
    cyclohexanone 1333.66
    propylene glycol 233.2
    isopropyl acetate 477.11
    DMAc 611.56
    2-ethoxyethanol 491.0
    isopentanol 587.18
    n-heptane 371.93
    ethyl formate 518.86
    1,2-dichloroethane 914.33
    n-hexanol 1072.52
    2-methoxyethanol 881.47
    isobutyl acetate 266.72
    tetrachloromethane 455.37
    n-pentyl acetate 363.01
    transcutol 1013.92
    n-heptanol 325.23
    ethylbenzene 215.33
    MIBK 406.92
    2-propoxyethanol 1123.91
    tert-butanol 683.17
    MTBE 850.83
    2-butoxyethanol 411.41
    propionic acid 644.8
    o-xylene 317.25
    formic acid 363.16
    diethyl ether 1516.87
    m-xylene 406.75
    p-xylene 255.19
    chlorobenzene 558.68
    dimethyl carbonate 294.66
    n-octane 106.18
    formamide 321.83
    cyclopentanone 1255.39
    2-pentanone 783.36
    anisole 327.73
    cyclopentyl methyl ether 1479.24
    gamma-butyrolactone 1303.25
    1-methoxy-2-propanol 606.74
    pyridine 774.72
    3-pentanone 697.36
    furfural 729.21
    n-dodecane 67.37
    diethylene glycol 560.82
    diisopropyl ether 408.87
    tert-amyl alcohol 615.58
    acetylacetone 613.06
    n-hexadecane 76.69
    acetophenone 236.25
    methyl propionate 745.1
    isopentyl acetate 510.93
    trichloroethylene 1155.64
    n-nonanol 301.66
    cyclohexanol 959.25
    benzyl alcohol 255.75
    2-ethylhexanol 554.15
    isooctanol 241.37
    dipropyl ether 722.49
    1,2-dichlorobenzene 355.99
    ethyl lactate 147.7
    propylene carbonate 593.02
    n-methylformamide 531.13
    2-pentanol 594.6
    n-pentane 464.88
    1-propoxy-2-propanol 713.66
    1-methoxy-2-propyl acetate 527.7
    2-(2-methoxypropoxy) propanol 276.33
    mesitylene 235.2
    ε-caprolactone 1028.91
    p-cymene 169.65
    epichlorohydrin 1262.85
    1,1,1-trichloroethane 897.82
    2-aminoethanol 369.71
    morpholine-4-carbaldehyde 896.7
    sulfolane 1033.52
    2,2,4-trimethylpentane 151.16
    2-methyltetrahydrofuran 1976.84
    n-hexyl acetate 559.58
    isooctane 112.82
    2-(2-butoxyethoxy)ethanol 417.09
    sec-butyl acetate 257.14
    tert-butyl acetate 473.79
    decalin 181.96
    glycerin 285.91
    diglyme 656.92
    acrylic acid 486.27
    isopropyl myristate 184.45
    n-butyric acid 788.93
    acetyl acetate 506.92
    di(2-ethylhexyl) phthalate 168.67
    ethyl propionate 377.75
    nitromethane 917.04
    1,2-diethoxyethane 582.88
    benzonitrile 328.05
    trioctyl phosphate 132.96
    1-bromopropane 935.24
    gamma-valerolactone 1234.36
    n-decanol 218.09
    triethyl phosphate 154.11
    4-methyl-2-pentanol 283.87
    propionitrile 641.54
    vinylene carbonate 527.44
    1,1,2-trichlorotrifluoroethane 569.33
    DMS 374.11
    cumene 153.36
    2-octanol 241.75
    2-hexanone 446.69
    octyl acetate 263.21
    limonene 350.5
    1,2-dimethoxyethane 735.35
    ethyl orthosilicate 165.83
    tributyl phosphate 167.02
    diacetone alcohol 398.23
    N,N-dimethylaniline 209.41
    acrylonitrile 528.54
    aniline 526.63
    1,3-propanediol 494.41
    bromobenzene 555.88
    dibromomethane 1232.01
    1,1,2,2-tetrachloroethane 839.35
    2-methyl-cyclohexyl acetate 289.06
    tetrabutyl urea 194.58
    diisobutyl methanol 210.78
    2-phenylethanol 378.93
    styrene 260.4
    dioctyl adipate 215.7
    dimethyl sulfate 332.7
    ethyl butyrate 359.78
    methyl lactate 234.46
    butyl lactate 209.3
    diethyl carbonate 208.27
    propanediol butyl ether 288.61
    triethyl orthoformate 253.57
    p-tert-butyltoluene 163.49
    methyl 4-tert-butylbenzoate 254.83
    morpholine 1556.3
    tert-butylamine 517.81
    n-dodecanol 170.27
    dimethoxymethane 772.71
    ethylene carbonate 531.79
    cyrene 240.33
    2-ethoxyethyl acetate 444.02
    2-ethylhexyl acetate 466.36
    1,2,4-trichlorobenzene 411.77
    4-methylpyridine 894.52
    dibutyl ether 471.14
    2,6-dimethyl-4-heptanol 210.78
    DEF 716.2
    dimethyl isosorbide 480.29
    tetrachloroethylene 651.3
    eugenol 221.97
    triacetin 293.08
    span 80 303.73
    1,4-butanediol 201.67
    1,1-dichloroethane 968.81
    2-methyl-1-pentanol 433.26
    methyl formate 478.85
    2-methyl-1-butanol 648.41
    n-decane 120.67
    butyronitrile 700.78
    3,7-dimethyl-1-octanol 315.43
    1-chlorooctane 305.47
    1-chlorotetradecane 122.1
    n-nonane 142.03
    undecane 85.59
    tert-butylcyclohexane 172.51
    cyclooctane 262.64
    cyclopentanol 932.68
    tetrahydropyran 1953.88
    tert-amyl methyl ether 707.54
    2,5,8-trioxanonane 421.61
    1-hexene 784.15
    2-isopropoxyethanol 331.0
    2,2,2-trifluoroethanol 272.76
    methyl butyrate 440.97

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction