2-Ethyl-6-methylpyrazine

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    13925-03-6

    Molecular formula
    C7H10N2

    SMILES
    CCC1=NC(=CN=C1)C

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Nutty 83.3%
    Roasted 80.81%
    Cocoa 65.17%
    Hazelnut 63.68%
    Coffee 56.27%
    Earthy 56.23%
    Potato 53.86%
    Musty 52.75%
    Chocolate 49.11%
    Burnt 48.74%

    Scent© AI

  • Properties

    XLogP3-AA
    1.0

    Molecular weight
    122.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Boiling point

    • 80.00 °C. @ 50.00 mm Hg

    Flash point est.
    61.08 ˚C

    Solubility expt.

    • soluble in water, organic solvents
    • miscible at room temperature (in ethanol)

  • Synonyms

    • 2-ETHYL-6-METHYLPYRAZINE
    • 13925-03-6
    • Pyrazine, 2-ethyl-6-methyl-
    • 2-Methyl-6-ethylpyrazine
    • 2,6-Methylethylpyrazine
    • UNII-A9BL9OKQ7T
    • A9BL9OKQ7T
    • Pyrazine, 6-ethyl-2-methyl
    • EINECS 237-692-0
    • 2-ethyl-6-methyl-pyrazine
    • FEMA NO. 3919
    • FEMA 3919
    • 6-METHYL-2-ETHYLPYRAZINE
    • DTXSID60160977
    • 2-ETHYL-6-METHYLPYRAZINE [FHFI]
    • PYRAZINE,2-ETHYL-6-METHYL-
    • MFCD00055035
    • SCHEMBL105987
    • CHEMBL4522941
    • DTXCID0083468
    • CHEBI:193621
    • NAA92503
    • AKOS006283739
    • DS-20136
    • DB-116794
    • CS-0161293
    • NS00021636
    • D84033
    • EN300-300011
    • Q27273802
    • 237-692-0

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 260.07
    methanol 419.46
    isopropanol 178.48
    water 3.32
    ethyl acetate 276.88
    n-propanol 225.88
    acetone 364.88
    n-butanol 216.9
    acetonitrile 253.01
    DMF 535.57
    toluene 212.59
    isobutanol 193.16
    1,4-dioxane 480.1
    methyl acetate 245.43
    THF 626.83
    2-butanone 327.82
    n-pentanol 196.71
    sec-butanol 202.94
    n-hexane 87.27
    ethylene glycol 91.49
    NMP 663.82
    cyclohexane 85.77
    DMSO 558.55
    n-butyl acetate 330.96
    n-octanol 152.81
    chloroform 973.42
    n-propyl acetate 200.67
    acetic acid 316.67
    dichloromethane 995.13
    cyclohexanone 519.32
    propylene glycol 98.47
    isopropyl acetate 174.55
    DMAc 492.78
    2-ethoxyethanol 241.74
    isopentanol 197.34
    n-heptane 66.42
    ethyl formate 234.27
    1,2-dichloroethane 520.36
    n-hexanol 269.9
    2-methoxyethanol 348.65
    isobutyl acetate 151.56
    tetrachloromethane 254.06
    n-pentyl acetate 203.56
    transcutol 588.41
    n-heptanol 136.75
    ethylbenzene 129.65
    MIBK 182.51
    2-propoxyethanol 351.79
    tert-butanol 210.99
    MTBE 260.29
    2-butoxyethanol 208.91
    propionic acid 234.38
    o-xylene 160.07
    formic acid 136.98
    diethyl ether 283.07
    m-xylene 162.24
    p-xylene 179.86
    chlorobenzene 375.82
    dimethyl carbonate 132.04
    n-octane 32.52
    formamide 113.33
    cyclopentanone 600.52
    2-pentanone 263.55
    anisole 213.66
    cyclopentyl methyl ether 354.77
    gamma-butyrolactone 648.84
    1-methoxy-2-propanol 256.59
    pyridine 405.91
    3-pentanone 254.92
    furfural 601.89
    n-dodecane 27.54
    diethylene glycol 240.54
    diisopropyl ether 106.95
    tert-amyl alcohol 229.87
    acetylacetone 292.15
    n-hexadecane 30.86
    acetophenone 217.96
    methyl propionate 238.02
    isopentyl acetate 270.31
    trichloroethylene 942.86
    n-nonanol 122.79
    cyclohexanol 224.45
    benzyl alcohol 180.61
    2-ethylhexanol 198.3
    isooctanol 115.74
    dipropyl ether 204.73
    1,2-dichlorobenzene 355.77
    ethyl lactate 116.76
    propylene carbonate 376.05
    n-methylformamide 237.45
    2-pentanol 157.88
    n-pentane 67.27
    1-propoxy-2-propanol 256.1
    1-methoxy-2-propyl acetate 232.03
    2-(2-methoxypropoxy) propanol 186.23
    mesitylene 116.03
    ε-caprolactone 417.3
    p-cymene 120.16
    epichlorohydrin 633.79
    1,1,1-trichloroethane 544.29
    2-aminoethanol 137.24
    morpholine-4-carbaldehyde 519.78
    sulfolane 863.06
    2,2,4-trimethylpentane 53.57
    2-methyltetrahydrofuran 494.38
    n-hexyl acetate 277.32
    isooctane 35.94
    2-(2-butoxyethoxy)ethanol 235.62
    sec-butyl acetate 140.33
    tert-butyl acetate 194.76
    decalin 62.89
    glycerin 143.75
    diglyme 423.87
    acrylic acid 234.04
    isopropyl myristate 113.06
    n-butyric acid 287.82
    acetyl acetate 193.38
    di(2-ethylhexyl) phthalate 126.11
    ethyl propionate 188.59
    nitromethane 390.61
    1,2-diethoxyethane 278.11
    benzonitrile 307.34
    trioctyl phosphate 93.98
    1-bromopropane 359.13
    gamma-valerolactone 615.12
    n-decanol 95.59
    triethyl phosphate 118.29
    4-methyl-2-pentanol 104.67
    propionitrile 246.93
    vinylene carbonate 370.35
    1,1,2-trichlorotrifluoroethane 411.04
    DMS 199.12
    cumene 112.15
    2-octanol 109.8
    2-hexanone 229.29
    octyl acetate 146.12
    limonene 161.31
    1,2-dimethoxyethane 401.63
    ethyl orthosilicate 115.07
    tributyl phosphate 122.76
    diacetone alcohol 193.71
    N,N-dimethylaniline 177.04
    acrylonitrile 295.99
    aniline 226.01
    1,3-propanediol 181.11
    bromobenzene 430.1
    dibromomethane 679.93
    1,1,2,2-tetrachloroethane 727.9
    2-methyl-cyclohexyl acetate 181.94
    tetrabutyl urea 148.62
    diisobutyl methanol 108.35
    2-phenylethanol 219.87
    styrene 160.57
    dioctyl adipate 152.33
    dimethyl sulfate 241.46
    ethyl butyrate 216.87
    methyl lactate 137.2
    butyl lactate 153.83
    diethyl carbonate 152.76
    propanediol butyl ether 189.12
    triethyl orthoformate 151.59
    p-tert-butyltoluene 113.86
    methyl 4-tert-butylbenzoate 191.57
    morpholine 426.75
    tert-butylamine 159.12
    n-dodecanol 79.18
    dimethoxymethane 314.46
    ethylene carbonate 292.69
    cyrene 201.91
    2-ethoxyethyl acetate 224.75
    2-ethylhexyl acetate 230.05
    1,2,4-trichlorobenzene 412.46
    4-methylpyridine 451.26
    dibutyl ether 201.77
    2,6-dimethyl-4-heptanol 108.35
    DEF 362.67
    dimethyl isosorbide 324.34
    tetrachloroethylene 533.04
    eugenol 204.83
    triacetin 203.62
    span 80 174.44
    1,4-butanediol 110.87
    1,1-dichloroethane 485.16
    2-methyl-1-pentanol 201.14
    methyl formate 236.55
    2-methyl-1-butanol 215.5
    n-decane 41.8
    butyronitrile 290.2
    3,7-dimethyl-1-octanol 138.69
    1-chlorooctane 142.62
    1-chlorotetradecane 63.78
    n-nonane 45.65
    undecane 32.68
    tert-butylcyclohexane 67.4
    cyclooctane 40.09
    cyclopentanol 264.33
    tetrahydropyran 420.37
    tert-amyl methyl ether 238.13
    2,5,8-trioxanonane 278.32
    1-hexene 190.05
    2-isopropoxyethanol 183.03
    2,2,2-trifluoroethanol 127.93
    methyl butyrate 252.94

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Chicory root, roasted 2 68650-43-1 Cichorium intybus L., fam. Asteraceae (Compositae) 0.83%
Chicory root, roasted 1a 68650-43-1 Cichorium intybus L., fam. Asteraceae (Compositae) 0.11%
Chicory root, roasted 1b 68650-43-1 Cichorium intybus L., fam. Asteraceae (Compositae) 0.1%
Mandarin (Italy) 8 8008-31-9 Citrus deliciosa Tenore (C. reticulata Blanco, cv.mandarin), fam. Rutaceae 0.01%