2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    27538-10-9

    Molecular formula
    C7H10O3

    SMILES
    CCC1C(=O)C(=C(O1)C)O

    Safety labels

    Irritant
    Irritant

    Retention indicies (RI)

    • Carbowax: 2073.0

  • Odor profile

    Caramellic 89.69%
    Sweet 80.7%
    Burnt 62.41%
    Fruity 61.09%
    Roasted 49.57%
    Buttery 42.86%
    Coffee 40.15%
    Nutty 38.74%
    Strawberry 33.03%
    Creamy 29.34%

    Scent© AI

  • Properties

    XLogP3-AA
    1.2

    Molecular weight
    142.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point

    • 103.00 °C. @ 15.00 mm Hg

    Flash point est.
    103.07 ˚C

  • Synonyms

    • 27538-10-9
    • 2-Ethyl-4-hydroxy-5-methyl-3(2H)-furanone
    • Ethyl furaneol
    • homofuraneol
    • 2-Ethyl-4-hydroxy-5-methylfuran-3(2H)-one
    • 3(2H)-FURANONE, 2-ETHYL-4-HYDROXY-5-METHYL-
    • CCRIS 6903
    • 4-Hydroxy-2-ethyl-5-methyl-3(2H)-furanone
    • 2-ethyl-4-hydroxy-5-methylfuran-3-one
    • Homofureanol
    • VRF4YF0C3X
    • EINECS 248-514-6
    • BRN 1617449
    • HEMF
    • MFCD00191360
    • 4-Hydroxy-2-ethyl-5-methyl-3-furanone
    • HOMOFURANEOL, 2-ETHYL-
    • CHEBI:137995
    • DTXSID40885393
    • FEMA NO. 3623, 2-ETHYL-
    • 2-METHYL-3-HYDROXY-5-ETHYLFURAN-4-ONE
    • 2-METHYL-5-ETHYL-4,5-DIHYDROFURAN-3-OL-4-ONE
    • 2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone (homofuraneol)
    • (+/-)-2-ETHYL-4-HYDROXY-5-METHYL-3(2H)-FURANONE
    • 2-ETHYL-4-HYDROXY-5-METHYL-3(2H)-FURANONE [FHFI]
    • 4-HYDROXY-2-ETHYL-5-METHYL-2,3-DIHYDROFURAN-3-ONE
    • 4-HYDROXY-5-METHYL-2-ETHYL-2,3-DIHYDROFURAN-3-ONE
    • 2-ETHYL-4-HYDROXY-5-METHYL-3(2H)-FURANONE, (+/-)-
    • 2-Ethyl-4-hydroxy-5-methyl-3(2H)furanone
    • UNII-VRF4YF0C3X
    • 4-HEMF
    • EHMF cpd
    • SCHEMBL112481
    • DTXCID201024776
    • DTXCID501024775
    • AKOS015914386
    • CS-W014372
    • SB60887
    • 2-ethyl-4-hydroxy-5-methyl-3-furanone
    • SY053112
    • 2-ethyl-5-methyl-4-oxidanyl-furan-3-one
    • E0428
    • NS00012415
    • H11381
    • A819109
    • 2-ethyl-4-hydroxy-5-methyl-2,3-dihydrofuran-3-one
    • 4-Hydroxy-2-methyl-5-ethyl-2,3-dihydrofur-3-one
    • Q27291987
    • Ethyl 4-hydroxy-5-methyl-3(2H)-furanone (homofuraneol)
    • 4-Hydroxy-2- or 5-ethyl-5- and 2-methyl-3(2H)-furanone
    • 2-Ethyl-4-hydroxy-5-methyl-3(2H)-furanone (mixture of isomers)

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 607.07
    methanol 1258.25
    isopropanol 306.02
    water 106.98
    ethyl acetate 286.28
    n-propanol 388.67
    acetone 577.5
    n-butanol 302.92
    acetonitrile 524.29
    DMF 881.45
    toluene 57.99
    isobutanol 243.61
    1,4-dioxane 659.97
    methyl acetate 361.09
    THF 507.47
    2-butanone 314.74
    n-pentanol 247.5
    sec-butanol 253.32
    n-hexane 12.22
    ethylene glycol 516.91
    NMP 362.82
    cyclohexane 11.76
    DMSO 1067.8
    n-butyl acetate 169.39
    n-octanol 135.97
    chloroform 654.63
    n-propyl acetate 208.37
    acetic acid 593.53
    dichloromethane 864.78
    cyclohexanone 300.99
    propylene glycol 273.17
    isopropyl acetate 166.8
    DMAc 406.79
    2-ethoxyethanol 768.58
    isopentanol 227.87
    n-heptane 9.14
    ethyl formate 365.34
    1,2-dichloroethane 530.56
    n-hexanol 160.07
    2-methoxyethanol 1114.7
    isobutyl acetate 108.93
    tetrachloromethane 114.3
    n-pentyl acetate 149.76
    transcutol 782.56
    n-heptanol 114.59
    ethylbenzene 61.99
    MIBK 167.78
    2-propoxyethanol 437.4
    tert-butanol 339.33
    MTBE 216.11
    2-butoxyethanol 279.81
    propionic acid 314.66
    o-xylene 68.29
    formic acid 800.47
    diethyl ether 236.68
    m-xylene 61.96
    p-xylene 87.04
    chlorobenzene 164.79
    dimethyl carbonate 175.25
    n-octane 8.98
    formamide 962.04
    cyclopentanone 419.38
    2-pentanone 253.74
    anisole 199.74
    cyclopentyl methyl ether 169.97
    gamma-butyrolactone 595.14
    1-methoxy-2-propanol 552.2
    pyridine 301.6
    3-pentanone 181.04
    furfural 672.46
    n-dodecane 10.28
    diethylene glycol 565.31
    diisopropyl ether 67.58
    tert-amyl alcohol 267.74
    acetylacetone 353.5
    n-hexadecane 11.46
    acetophenone 192.13
    methyl propionate 255.5
    isopentyl acetate 147.68
    trichloroethylene 821.85
    n-nonanol 111.06
    cyclohexanol 155.72
    benzyl alcohol 222.16
    2-ethylhexanol 86.65
    isooctanol 94.79
    dipropyl ether 75.92
    1,2-dichlorobenzene 189.37
    ethyl lactate 159.61
    propylene carbonate 294.81
    n-methylformamide 737.08
    2-pentanol 176.5
    n-pentane 12.71
    1-propoxy-2-propanol 217.13
    1-methoxy-2-propyl acetate 177.64
    2-(2-methoxypropoxy) propanol 192.11
    mesitylene 49.67
    ε-caprolactone 290.61
    p-cymene 48.34
    epichlorohydrin 735.77
    1,1,1-trichloroethane 316.05
    2-aminoethanol 547.13
    morpholine-4-carbaldehyde 593.04
    sulfolane 683.5
    2,2,4-trimethylpentane 14.0
    2-methyltetrahydrofuran 280.18
    n-hexyl acetate 205.51
    isooctane 10.96
    2-(2-butoxyethoxy)ethanol 287.39
    sec-butyl acetate 121.89
    tert-butyl acetate 191.33
    decalin 15.25
    glycerin 482.19
    diglyme 574.57
    acrylic acid 344.11
    isopropyl myristate 71.8
    n-butyric acid 320.85
    acetyl acetate 199.2
    di(2-ethylhexyl) phthalate 80.0
    ethyl propionate 174.31
    nitromethane 1130.9
    1,2-diethoxyethane 230.49
    benzonitrile 249.58
    trioctyl phosphate 63.75
    1-bromopropane 168.54
    gamma-valerolactone 641.23
    n-decanol 81.88
    triethyl phosphate 76.28
    4-methyl-2-pentanol 108.34
    propionitrile 293.66
    vinylene carbonate 337.19
    1,1,2-trichlorotrifluoroethane 525.11
    DMS 193.8
    cumene 57.34
    2-octanol 94.63
    2-hexanone 186.1
    octyl acetate 97.31
    limonene 58.91
    1,2-dimethoxyethane 749.18
    ethyl orthosilicate 72.7
    tributyl phosphate 70.79
    diacetone alcohol 240.54
    N,N-dimethylaniline 126.59
    acrylonitrile 474.29
    aniline 147.08
    1,3-propanediol 648.83
    bromobenzene 142.52
    dibromomethane 439.77
    1,1,2,2-tetrachloroethane 547.3
    2-methyl-cyclohexyl acetate 97.51
    tetrabutyl urea 90.08
    diisobutyl methanol 61.43
    2-phenylethanol 165.42
    styrene 78.24
    dioctyl adipate 97.03
    dimethyl sulfate 293.0
    ethyl butyrate 125.22
    methyl lactate 205.69
    butyl lactate 133.21
    diethyl carbonate 95.36
    propanediol butyl ether 272.78
    triethyl orthoformate 93.53
    p-tert-butyltoluene 47.13
    methyl 4-tert-butylbenzoate 172.57
    morpholine 534.08
    tert-butylamine 173.25
    n-dodecanol 61.38
    dimethoxymethane 570.84
    ethylene carbonate 277.83
    cyrene 191.6
    2-ethoxyethyl acetate 219.65
    2-ethylhexyl acetate 109.25
    1,2,4-trichlorobenzene 219.15
    4-methylpyridine 239.18
    dibutyl ether 94.41
    2,6-dimethyl-4-heptanol 61.43
    DEF 277.68
    dimethyl isosorbide 276.66
    tetrachloroethylene 445.45
    eugenol 214.16
    triacetin 185.22
    span 80 143.35
    1,4-butanediol 367.28
    1,1-dichloroethane 354.46
    2-methyl-1-pentanol 186.43
    methyl formate 708.82
    2-methyl-1-butanol 214.16
    n-decane 15.41
    butyronitrile 260.63
    3,7-dimethyl-1-octanol 100.14
    1-chlorooctane 69.76
    1-chlorotetradecane 30.04
    n-nonane 13.64
    undecane 12.34
    tert-butylcyclohexane 16.03
    cyclooctane 6.85
    cyclopentanol 197.27
    tetrahydropyran 239.32
    tert-amyl methyl ether 161.17
    2,5,8-trioxanonane 338.66
    1-hexene 50.94
    2-isopropoxyethanol 392.21
    2,2,2-trifluoroethanol 362.11
    methyl butyrate 246.89

    Scent© AI

1 4

IFRA standard 51

Recommendation
Restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 0.045 % Category 7A
Rinse-off products applied to the hair with some hand contact
 0.52 %
Category 2
Products applied to the axillae
 0.014 % Category 7B
Leave-on products applied to the hair with some hand contact
 0.52 %
Category 3
Products applied to the face/body using fingertips
 0.27 % Category 8
Products with significant anogenital exposure
 0.021 %
Category 4
Products related to fine fragrance
 0.25 % Category 9
Products with body and hand exposure, primarily rinse off
 0.49 %
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 0.064 % Category 10A
Household care products with mostly hand contact
 0.98 %
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 0.064 % Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 1.8 %
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 0.064 % Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 0.021 %
Category 5D
Baby Creams, baby Oils and baby talc
 0.021 % Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 0.021 %
Category 6
Products with oral and lip exposure
 0.15 % Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Mandrake fruit (Israel) Mandragora officinarum L., fam. Solanaceae 0.04%