1,4-Cineole

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    470-67-7

    Molecular formula
    C10H18O

    SMILES
    CC(C)C12CCC(O1)(CC2)C

    Safety labels

    Flammable
    Flammable

    Retention indicies (RI)

    • DB5: 1014.0
    • Carbowax: 1184.0

  • Odor profile

    green 80.09%
    herbal 72.65%
    mint 68.14%
    fresh 63.83%
    cooling 60.05%
    camphoreous 58.67%
    woody 47.96%
    earthy 46.51%
    terpenic 44.56%
    pine 43.84%

    Scent© AI

  • Properties

    XLogP3-AA
    2.5 Well soluble in DEP, IAA, BB

    Molecular weight
    154.25 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very fast

    Melting point expt.

    • 1 °C

    Boiling point

    • 173-174 °C
    • 65.00 °C. @ 16.00 mm Hg

    Solubility expt.

    • SLIGHTLY SOL IN WATER; SOL IN BENZENE, PETROLEUM ETHER; SOL IN ALL PROPORTION IN ETHER, ALC
    • Insoluble in water, soluble in oils
    • soluble (in ethanol)

  • Synonyms

    • 1,4-Cineole
    • 470-67-7
    • Isocineole
    • 1,4-Cineol
    • 1,4-EPOXY-P-MENTHANE
    • 1,4-Cineole (natural)
    • p-Menthane, 1,4-epoxy-
    • FEMA No. 3658
    • Isocineple
    • 1-methyl-4-propan-2-yl-7-oxabicyclo[2.2.1]heptane
    • 1-Methyl-4-(1-methylethyl)-7-oxabicyclo(2.2.1)heptane
    • HSDB 5425
    • p-Menthane, 1,4-epoxy
    • EINECS 207-428-9
    • UNII-B55JTU839B
    • BRN 0104974
    • 1-Isopropyl-4-methyl-7-oxabicyclo(2.2.1)heptane
    • 1-Isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane
    • CHEBI:80788
    • 1-methyl-4-(propan-2-yl)-7-oxabicyclo[2.2.1]heptane
    • 7-Oxabicyclo(2.2.1)heptane, 1-methyl-4-(1-methylethyl)-
    • 7-Oxabicyclo(2.2.1)heptane, 1-isopropyl-4-methyl-
    • 1,4-CINEOLE [FHFI]
    • B55JTU839B
    • 7-Oxabicyclo[2.2.1]heptane, 1-methyl-4-(1-methylethyl)-
    • DTXSID3047396
    • 1-METHYL-4-(1-METHYLETHYL)-7-OXABICYCLO[2.2.1]HEPTANE
    • 5-17-01-00273 (Beilstein Handbook Reference)
    • (+/-)-1,4-CINEOLE
    • 1,4-EPOXY-P-MENTHANE [HSDB]
    • 1-isopropyl-4-methylbicyclo[2.2.1]heptane
    • 4-isopropyl-1-methyl-7-oxabicyclo[2.2.1]heptane
    • (1s,4s)-1-methyl-4-(propan-2-yl)-7-oxabicyclo[2.2.1]heptane
    • 1-Methyl-4-(1-methylethyl)-7-oxabicyclo[2.2.1]heptane, 9CI
    • 1-Isopropyl-4-methylbicyclo(2.2.1)heptane
    • 1-methyl-4-propan-2-yl-7-oxabicyclo(2.2.1)heptane
    • 1-methyl-4-(propan-2-yl)-7-oxabicyclo(2.2.1)heptane
    • pCineole
    • 1-Methyl-4-(1-methylethyl)-7-oxabicyclo(2.2.1)heptane, 9ci
    • (1S,4S)-1-Methyl-4-(propan-2-yl)-7-oxabicyclo(2.2.1)heptane
    • 1,4Cineole
    • 1,4Cineol
    • MFCD00209502
    • pMenthane, 1,4epoxy
    • 1,4Cineole (natural)
    • 1,4-Cineole (Standard)
    • SCHEMBL231925
    • 1,4-Cineole, >=85%
    • CHEMBL2288022
    • SCHEMBL13180469
    • SCHEMBL15450554
    • SCHEMBL18993155
    • HY-N7117R
    • 1,4-Cineole, analytical standard
    • RFFOTVCVTJUTAD-AOOOYVTPSA-N
    • 7-Oxabicyclo(2.2.1)heptane, 1-isopropyl-4-methyl- (6CI)
    • DTXCID201473981
    • 1,4-Cineole, >=95%, FG
    • HY-N7117
    • s5419
    • CCG-266250
    • AS-81210
    • DA-49175
    • 1ST159200
    • 1Isopropyl4methyl7oxabicyclo(2.2.1)heptane
    • C3652
    • CS-0066997
    • NS00012694
    • 7Oxabicyclo(2.2.1)heptane, 1isopropyl4methyl
    • C16909
    • F82275
    • 1Methyl4(1methylethyl)7oxabicyclo(2.2.1)heptane
    • 7Oxabicyclo(2.2.1)heptane, 1methyl4(1methylethyl)
    • 1-Isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane #
    • 7Oxabicyclo(2.2.1)heptane, 1isopropyl4methyl (6CI)
    • Q12470088
1 4

IFRA Standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Bergamot (China) 1 8007-75-8 Citrus bergamia Risso et Poiteau, fam. Rutaceae 0.01%
Blackcurrant bud 1 68606-81-5 Ribes nigrum L., fam. Grossulariaceae 0.05%
Lime (Mexican, West Indian, Key) 1 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 0.01%
Lime (Mexican, West Indian, Key) 2 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 0.01%
Lime (Mexican, West Indian, Key) 3 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 1.0%
Lime (Persian) 1 90063-52-8 Citrus latifolia Tanaka, fam. Rutaceae 0.01%
Lime (Persian) 2 90063-52-8 Citrus latifolia Tanaka, fam. Rutaceae 1.0%
Lime (Mexican, West Indian, Key) 4 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 1.7%
Nutmeg (India) 2 8008-45-5 Myristica fragrans Houtt., fam. Myristicaceae 0.3%
Tea Tree (Australia) 1 68647-73-4 Melaleuca alternifolia (Maiden et Betche) Cheel, fam. Myrtaceae 0.01%
Yuzu (Japan) 2 Citrus junos Sieb. ex Tanaka, fam. Rutaceae 0.02%
Pistacia lentiscus (Spain) 1a leaf 90082-83-0 Pistacia lentiscus L., fam. Anacardiaceae 0.01%
Tea Tree (Australia) 7 68647-73-4 Melaleuca alternifolia (Maiden et Betche) Cheel, fam. Myrtaceae 0.01%
Hyptis suaveolens (India) 1 Hyptis suaveolens (L.) Poit., fam. Lamiaceae (Labiatae) 0.6%
Cedrus atlantica (Morocco) Cedrus atlantica Man., fam. Cupressaceae 0.01%
Lilac, White, Picked Flower Headspace 1 Syringa vulgaris L., fam. Oleaceae 0.17%
Laurel leaf (China) 8006-78-8 Laurus nobilis L., fam. Lauraceae 0.2%
Eucalyptus globulus (China) 1 8016-26-0 Eucalyptus globulus Labill., fam. Myrtaceae 0.8%
Terminalia bentzoe Terminalia bentzoe (L.) L.f.ssp.rodriguesensis Wickens, fam. Combretaceae 1.06%
Orange leaf, sweet (Mauritius) Citrus sinensis (L.) Osbeck, fam. Rutaceae 0.71%
Fir balsam 2b 8021-28-1 Abies balsamea (L.) Mill., fam. Pinaceae 0.09%
Citrus volkameriana (Colombia) Citrus volkameriana L., fam. Rutaceae 0.35%
Mandarin (Columbia) 8008-31-9 Citrus deliciosa Tenore (C. reticulata Blanco, cv.mandarin), fam. Rutaceae 0.08%
Heterotheca inuloides leaf (Mexico) Heterotheca inuloides Cass., fam. Asteraceae (Compositae) 0.23%
Tea Tree (Australia) 9 68647-73-4 Melaleuca alternifolia (Maiden et Betche) Cheel, fam. Myrtaceae 0.01%
Boldo leaf (Italy) Boldea fragrans Juss. (Peumus boldus Mol.) 0.92%
Boldo leaf (Chile) Boldea fragrans Juss. (Peumus boldus Mol.) 0.51%
Lime (Mexican, West Indian, Key) 5 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 2.32%
Lime (Mexican, West Indian, Key) (Peru) 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 3.52%
Lime (Mexican, West Indian, Key) (Ivory Coast) 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 3.72%
Lime (Mexican, West Indian, Key) 7 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 2.8%
Pistacia lentiscus (Spain) 3 whole plant 90082-83-0 Pistacia lentiscus L., fam. Anacardiaceae 0.01%
Port Orford Cedarwood Chamaecyparis lawsoniana (A. Murray) Parl., fam. Cupressaceae 1.3%
Bacuri fruit (Brazil) Platonia insignis M., fam. Guttiferae 0.3%
Carob bean extract 1 9000-40-2 Ceratonia siliqua L., fam. Leguminoseae 0.3%
Lime (Mexican, West Indian, Key) (Cuba) 8008-26-2 Citrus aurantifolia (Christm.) Swingle, fam. Rutaceae 2.0%
Lime (Persian) (Cuba) 90063-52-8 Citrus latifolia Tanaka, fam. Rutaceae 1.8%
Douglas fir (Bulgaria) Pseudotsuga menziesii (Mirbel) Franco, fam. Pinaceae 0.1%
Thymus fedtschenkoi (Iran) Thymus fedtschenkoi Ronniger, fam. Lamiaceae (Labiatae) 0.2%
Pinus canariensis (Spain-Tenerife) Pinus canariensis Sweet ex Sprengel, fam. Pinaceae 0.01%