1-Acetoxy-2-propanol

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  • Identifiers

    CAS number
    627-69-0

    Molecular formula
    C5H10O3

    SMILES
    CC(COC(=O)C)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fruity 84.23%
    Ethereal 50.32%
    Buttery 41.78%
    Sweet 37.18%
    Caramellic 37.01%
    Winey 28.98%
    Milky 28.59%
    Creamy 27.59%
    Alcoholic 26.07%
    Dairy 24.3%

    Scent© AI

  • Properties

    XLogP3-AA
    -0.2

    Molecular weight
    118.13 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Fast

    Boiling point est.
    170°C

    Flash point est.
    79.66 ˚C

  • Synonyms

    • 2-hydroxypropyl acetate
    • 627-69-0
    • 1,2-Propanediol, 1-acetate
    • 1,2-Propanediol-1-Acetate
    • 1,2-Propanediol, monoacetate
    • Propylene glycol 1-acetate
    • Propylene glycol monoacetate
    • 1-acetoxy-2-propanol
    • 2-HYDROXYPROPYLACETATE
    • Acetic acid, 2-hydroxypropyl ester
    • 1-Acetoxy-2-hydroxypropane
    • EINECS 215-555-6
    • 359T9N1SED
    • NSC 35664
    • NSC-35664
    • DTXSID90892234
    • 1,2-Propanediol-1-Acetate (>75%)
    • MFCD00127735
    • 1, 1-acetate
    • 1-Acetoxy propylene glycol
    • UNII-359T9N1SED
    • SCHEMBL36039
    • Propane-1,2-diol,monoacetate
    • DTXCID6030231
    • NSC35664
    • NSC87502
    • NSC-87502
    • AKOS015915377
    • AB93374
    • SY272306
    • NS00019588
    • F79778
    • EN300-2010180
    • 1-Acetoxy propylene glycol; 1-Acetoxy-2-hydroxypropane; 1-Acetoxy-2-propanol2-Hydroxypropyl acetate; NSC 35664
    • 613-080-2

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 298.87
    methanol 610.19
    isopropanol 195.4
    water 460.59
    ethyl acetate 38.66
    n-propanol 171.45
    acetone 117.63
    n-butanol 126.69
    acetonitrile 73.62
    DMF 504.58
    toluene 7.56
    isobutanol 110.79
    1,4-dioxane 99.48
    methyl acetate 65.64
    THF 129.91
    2-butanone 67.29
    n-pentanol 74.43
    sec-butanol 121.41
    n-hexane 4.22
    ethylene glycol 310.56
    NMP 253.58
    cyclohexane 2.48
    DMSO 390.63
    n-butyl acetate 22.51
    n-octanol 42.54
    chloroform 45.5
    n-propyl acetate 22.97
    acetic acid 218.64
    dichloromethane 56.45
    cyclohexanone 69.48
    propylene glycol 292.33
    isopropyl acetate 22.7
    DMAc 413.54
    2-ethoxyethanol 209.09
    isopentanol 91.94
    n-heptane 3.1
    ethyl formate 111.94
    1,2-dichloroethane 33.86
    n-hexanol 58.69
    2-methoxyethanol 433.49
    isobutyl acetate 15.75
    tetrachloromethane 10.74
    n-pentyl acetate 19.02
    transcutol 193.97
    n-heptanol 31.08
    ethylbenzene 9.14
    MIBK 32.06
    2-propoxyethanol 142.48
    tert-butanol 174.83
    MTBE 58.24
    2-butoxyethanol 76.13
    propionic acid 124.1
    o-xylene 12.17
    formic acid 372.02
    diethyl ether 28.35
    m-xylene 10.13
    p-xylene 11.45
    chlorobenzene 13.91
    dimethyl carbonate 28.23
    n-octane 1.93
    formamide 235.46
    cyclopentanone 99.78
    2-pentanone 43.73
    anisole 34.34
    cyclopentyl methyl ether 35.56
    gamma-butyrolactone 123.5
    1-methoxy-2-propanol 239.74
    pyridine 40.92
    3-pentanone 27.79
    furfural 169.19
    n-dodecane 2.4
    diethylene glycol 206.16
    diisopropyl ether 8.74
    tert-amyl alcohol 128.46
    acetylacetone 56.53
    n-hexadecane 2.49
    acetophenone 37.75
    methyl propionate 44.5
    isopentyl acetate 24.34
    trichloroethylene 51.93
    n-nonanol 33.8
    cyclohexanol 60.17
    benzyl alcohol 54.49
    2-ethylhexanol 29.08
    isooctanol 25.49
    dipropyl ether 16.21
    1,2-dichlorobenzene 18.58
    ethyl lactate 43.17
    propylene carbonate 71.19
    n-methylformamide 270.24
    2-pentanol 57.22
    n-pentane 3.83
    1-propoxy-2-propanol 82.57
    1-methoxy-2-propyl acetate 36.51
    2-(2-methoxypropoxy) propanol 88.62
    mesitylene 8.0
    ε-caprolactone 68.74
    p-cymene 9.61
    epichlorohydrin 104.41
    1,1,1-trichloroethane 21.99
    2-aminoethanol 334.41
    morpholine-4-carbaldehyde 258.56
    sulfolane 167.99
    2,2,4-trimethylpentane 3.84
    2-methyltetrahydrofuran 71.84
    n-hexyl acetate 34.85
    isooctane 2.49
    2-(2-butoxyethoxy)ethanol 95.61
    sec-butyl acetate 15.83
    tert-butyl acetate 27.49
    decalin 3.27
    glycerin 421.63
    diglyme 154.6
    acrylic acid 131.04
    isopropyl myristate 16.11
    n-butyric acid 106.92
    acetyl acetate 28.36
    di(2-ethylhexyl) phthalate 27.61
    ethyl propionate 23.73
    nitromethane 219.26
    1,2-diethoxyethane 34.9
    benzonitrile 39.17
    trioctyl phosphate 20.01
    1-bromopropane 20.08
    gamma-valerolactone 168.75
    n-decanol 25.13
    triethyl phosphate 20.46
    4-methyl-2-pentanol 35.12
    propionitrile 56.12
    vinylene carbonate 73.88
    1,1,2-trichlorotrifluoroethane 160.84
    DMS 27.73
    cumene 9.9
    2-octanol 22.23
    2-hexanone 31.31
    octyl acetate 22.1
    limonene 13.5
    1,2-dimethoxyethane 223.25
    ethyl orthosilicate 19.4
    tributyl phosphate 22.2
    diacetone alcohol 76.4
    N,N-dimethylaniline 35.89
    acrylonitrile 80.9
    aniline 32.64
    1,3-propanediol 292.68
    bromobenzene 9.74
    dibromomethane 29.52
    1,1,2,2-tetrachloroethane 51.08
    2-methyl-cyclohexyl acetate 23.67
    tetrabutyl urea 34.6
    diisobutyl methanol 17.85
    2-phenylethanol 38.84
    styrene 9.86
    dioctyl adipate 27.74
    dimethyl sulfate 70.76
    ethyl butyrate 20.36
    methyl lactate 83.54
    butyl lactate 36.2
    diethyl carbonate 17.49
    propanediol butyl ether 108.12
    triethyl orthoformate 20.48
    p-tert-butyltoluene 10.03
    methyl 4-tert-butylbenzoate 47.19
    morpholine 140.18
    tert-butylamine 83.26
    n-dodecanol 19.26
    dimethoxymethane 133.3
    ethylene carbonate 54.63
    cyrene 89.38
    2-ethoxyethyl acetate 28.99
    2-ethylhexyl acetate 17.58
    1,2,4-trichlorobenzene 24.06
    4-methylpyridine 51.54
    dibutyl ether 19.85
    2,6-dimethyl-4-heptanol 17.85
    DEF 96.15
    dimethyl isosorbide 91.55
    tetrachloroethylene 35.87
    eugenol 60.93
    triacetin 42.48
    span 80 62.8
    1,4-butanediol 140.06
    1,1-dichloroethane 28.2
    2-methyl-1-pentanol 62.87
    methyl formate 196.91
    2-methyl-1-butanol 89.76
    n-decane 3.46
    butyronitrile 63.06
    3,7-dimethyl-1-octanol 38.48
    1-chlorooctane 12.78
    1-chlorotetradecane 6.04
    n-nonane 3.26
    undecane 2.79
    tert-butylcyclohexane 4.27
    cyclooctane 1.37
    cyclopentanol 87.78
    tetrahydropyran 46.53
    tert-amyl methyl ether 45.66
    2,5,8-trioxanonane 121.98
    1-hexene 12.94
    2-isopropoxyethanol 99.32
    2,2,2-trifluoroethanol 105.85
    methyl butyrate 41.82

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction