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Ambrether aka. Woody Cyclohexanone alt. Kephalis Aroma Chemical
CAS# 36306-87-3

Woody, Herbal, Camphoreous, Tobacco, Mint

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Ambrether (also known by trade names and synonyms such as Kephalis, Woody Cyclohexanone, or 4-(1-ethoxyvinyl)-3,3,5,5-tetramethylcyclohexanone) with the CAS number 36306-87-3, is a highly important and favored synthetic fragrance ingredient in the perfumery and cosmetic industries. It is a clear liquid that ranges from colorless to pale yellow, which is highly soluble in alcohol and various organic solvents but practically insoluble in water.

The odor profile of Ambrether is incredibly rich and complex, serving as a solid heart and base note. Its most prominent characteristic is a warm woody and rich amber scent, delicately blended with nuances of dry tobacco and hot herbs. Upon deeper evaluation, users can detect facets of old wood, leather, suede, a slight honey-like sweetness, and a gentle powdery floral undertone reminiscent of muguet and violet. With impressive substantivity, Ambrether boasts a longevity of 80 to 100 hours on a smelling strip, helping to create depth, smoothness, and enhanced diffusion for the entire fragrance composition.

In formulation, Ambrether demonstrates excellent blending and synergistic capabilities with a wide range of other raw materials. It harmonizes perfectly with floral notes (such as rose, jasmine, violet, and lavender), spicy groups, and particularly shines when combined with Iso E Super, patchouli, sandalwood, or tobacco extracts. Furthermore, Ambrether (Kephalis) is a crucial building block in the synthetic reconstruction of complex aromas like agarwood (oud) and ambergris.

Thanks to this versatility, the applications of Ambrether are highly diverse. This compound is a "pillar" in many high-end perfume formulas, especially for men's and unisex fragrances with Oriental, woody, or leather profiles. Additionally, Ambrether is widely used to impart a luxurious and lasting scent to personal care products (such as shampoos, shower gels, lotions, and soaps) and home care products (like fabric softeners, scented candles, and detergents).

Regarding stability and safety, Ambrether performs exceptionally well in neutral and weakly alkaline environments (such as alcohol-based fine fragrances, scented candles, and bar soaps), as well as in fabric softeners. However, it can undergo degradation and lose its olfactory quality if used in highly acidic products with a pH below 3. Ambrether fully complies with IFRA (International Fragrance Association) safety standards, having no maximum concentration limits for use in finished products (including fine fragrances), and it contains no allergens restricted by the European Union Cosmetics Regulation. Nevertheless, in its pure concentrated form, this material is classified as a mild skin and eye irritant, and it is toxic to aquatic life with long-lasting effects, meaning it requires proper storage and handling.

7 total reviews

Technical standards

Solubility @25˚C

Solvent Solubility (g/L)
ethanol 1074.51
methanol 1485.92
isopropanol 990.39
water 12.43
ethyl acetate 1520.35
n-propanol 1078.94
acetone 1614.87
n-butanol 921.59
acetonitrile 1647.76
DMF 1787.53
toluene 1785.68
isobutanol 932.23
1,4-dioxane 2153.33
methyl acetate 1465.48
THF 4200.89
2-butanone 1252.33
n-pentanol 607.08
sec-butanol 956.53
n-hexane 458.17
ethylene glycol 255.08
NMP 2708.26
cyclohexane 1115.01
DMSO 841.04
n-butyl acetate 1051.73
n-octanol 564.45
chloroform 5107.18
n-propyl acetate 795.37
acetic acid 1786.28
dichloromethane 3598.2
cyclohexanone 2938.95
propylene glycol 389.57
isopropyl acetate 954.4
DMAc 1454.25
2-ethoxyethanol 489.91
isopentanol 733.82
n-heptane 442.56
ethyl formate 1116.58
1,2-dichloroethane 1814.25
n-hexanol 1289.58
2-methoxyethanol 949.9
isobutyl acetate 556.78
tetrachloromethane 1183.39
n-pentyl acetate 732.18
transcutol 1035.8
n-heptanol 496.45
ethylbenzene 713.22
MIBK 774.03
2-propoxyethanol 1095.53
tert-butanol 1092.14
MTBE 1035.62
2-butoxyethanol 482.47
propionic acid 1261.44
o-xylene 970.48
formic acid 657.95
diethyl ether 1175.85
m-xylene 1219.92
p-xylene 956.75
chlorobenzene 1851.5
dimethyl carbonate 662.58
n-octane 140.28
formamide 556.87
cyclopentanone 2925.94
2-pentanone 1229.6
anisole 786.59
cyclopentyl methyl ether 2378.99
gamma-butyrolactone 3581.14
1-methoxy-2-propanol 814.67
pyridine 2159.74
3-pentanone 1019.08
furfural 2074.43
n-dodecane 85.27
diethylene glycol 596.52
diisopropyl ether 495.68
tert-amyl alcohol 942.67
acetylacetone 1272.41
n-hexadecane 100.24
acetophenone 735.27
methyl propionate 1282.9
isopentyl acetate 836.49
trichloroethylene 3771.43
n-nonanol 450.16
cyclohexanol 1870.74
benzyl alcohol 729.74
2-ethylhexanol 719.43
isooctanol 371.16
dipropyl ether 750.53
1,2-dichlorobenzene 1357.04
ethyl lactate 372.17
propylene carbonate 1989.21
n-methylformamide 1185.3
2-pentanol 768.67
n-pentane 483.31
1-propoxy-2-propanol 756.04
1-methoxy-2-propyl acetate 946.6
2-(2-methoxypropoxy) propanol 423.41
mesitylene 751.63
ε-caprolactone 2370.2
p-cymene 472.93
epichlorohydrin 2695.0
1,1,1-trichloroethane 2632.44
2-aminoethanol 455.0
morpholine-4-carbaldehyde 1651.72
sulfolane 2402.37
2,2,4-trimethylpentane 197.19
2-methyltetrahydrofuran 3041.1
n-hexyl acetate 1154.11
isooctane 145.42
2-(2-butoxyethoxy)ethanol 503.54
sec-butyl acetate 556.12
tert-butyl acetate 888.93
decalin 346.52
glycerin 427.87
diglyme 893.17
acrylic acid 1111.11
isopropyl myristate 340.85
n-butyric acid 1571.56
acetyl acetate 1174.32
di(2-ethylhexyl) phthalate 329.91
ethyl propionate 767.25
nitromethane 2152.93
1,2-diethoxyethane 558.65
benzonitrile 1209.25
trioctyl phosphate 262.62
1-bromopropane 1463.68
gamma-valerolactone 2727.13
n-decanol 310.45
triethyl phosphate 344.13
4-methyl-2-pentanol 448.28
propionitrile 1219.4
vinylene carbonate 1828.41
1,1,2-trichlorotrifluoroethane 1499.12
DMS 868.3
cumene 464.01
2-octanol 441.03
2-hexanone 759.12
octyl acetate 461.55
limonene 748.32
1,2-dimethoxyethane 919.49
ethyl orthosilicate 325.01
tributyl phosphate 311.7
diacetone alcohol 716.65
N,N-dimethylaniline 533.3
acrylonitrile 1387.41
aniline 1311.33
1,3-propanediol 601.1
bromobenzene 1960.75
dibromomethane 2678.09
1,1,2,2-tetrachloroethane 2840.4
2-methyl-cyclohexyl acetate 604.95
tetrabutyl urea 368.42
diisobutyl methanol 319.01
2-phenylethanol 825.8
styrene 802.2
dioctyl adipate 446.58
dimethyl sulfate 854.47
ethyl butyrate 670.85
methyl lactate 540.48
butyl lactate 515.31
diethyl carbonate 479.61
propanediol butyl ether 492.28
triethyl orthoformate 464.0
p-tert-butyltoluene 467.1
methyl 4-tert-butylbenzoate 663.9
morpholine 2340.77
tert-butylamine 886.68
n-dodecanol 223.43
dimethoxymethane 1218.83
ethylene carbonate 1602.42
cyrene 554.29
2-ethoxyethyl acetate 730.87
2-ethylhexyl acetate 757.2
1,2,4-trichlorobenzene 1474.82
4-methylpyridine 2448.86
dibutyl ether 527.34
2,6-dimethyl-4-heptanol 319.01
DEF 1171.7
dimethyl isosorbide 905.67
tetrachloroethylene 2051.45
eugenol 502.2
triacetin 786.54
span 80 494.81
1,4-butanediol 256.28
1,1-dichloroethane 2331.32
2-methyl-1-pentanol 510.01
methyl formate 1222.69
2-methyl-1-butanol 794.9
n-decane 173.63
butyronitrile 1304.97
3,7-dimethyl-1-octanol 458.23
1-chlorooctane 535.31
1-chlorotetradecane 174.65
n-nonane 196.59
undecane 117.75
tert-butylcyclohexane 271.93
cyclooctane 418.9
cyclopentanol 1841.18
tetrahydropyran 3030.54
tert-amyl methyl ether 853.24
2,5,8-trioxanonane 596.98
1-hexene 832.63
2-isopropoxyethanol 387.16
2,2,2-trifluoroethanol 734.89
methyl butyrate 979.21

Scent© AI

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  • CAS NUMBER

    36306-87-3

  • FAMILIES

    Wood

  • BRAND

    Scent.vn

  • EVAPORATION RATE

    Slow

  • Odor impact

    Medium est.

  • FLASH POINT

    115.64 ˚C est.

heart base
Woody
Herbal
Camphoreous
Tobacco
Mint
Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
No restriction
Category 2
Products applied to the axillae
No restriction Category 7B
Leave-on products applied to the hair with some hand contact
No restriction
Category 3
Products applied to the face/body using fingertips
No restriction Category 8
Products with significant anogenital exposure
No restriction
Category 4
Products related to fine fragrance
No restriction Category 9
Products with body and hand exposure, primarily rinse off
No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
No restriction Category 10A
Household care products with mostly hand contact
No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
No restriction
Category 5D
Baby Creams, baby Oils and baby talc
No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
No restriction
Category 6
Products with oral and lip exposure
No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
No restriction
  • All orders will be processed within 1-2 business days from the time the order is confirmed.
  • Free shipping is available for international retail orders valued at 500 USD or more.
  • Delivery time is 1-3 business days for local areas, 3-7 days for suburban and nationwide deliveries, and 1-4 weeks for international orders.
  • You have 30 days from the date of receipt to initiate the return process.
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  • Certificate of Analysis (COA)

    Provides information on the physical and chemical properties of the product.
    Download  
  • IFRA Certificate of Conformity

    Sets safety standards and guidelines for the product in manufacturing.
    Download  
  • Safety Data Sheet (SDS)

    Provides important safety guidelines for transporting, storing, and using the product.
    Download  
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