Zingerol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    39728-80-8

    Molecular formula
    C11H16O3

    SMILES
    CC(CCC1=CC(=C(C=C1)O)OC)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 76.51%
    Vanilla 76.37%
    Spicy 50.9%
    Balsamic 50.86%
    Creamy 50.7%
    Floral 45.34%
    Powdery 42.33%
    Phenolic 39.51%
    Smoky 32.63%
    Clove 30.97%

     

    Flavor
    Sweet 77.25%
    Spicy 57.55%
    Woody 45.35%
    Floral 41.53%
    Vanilla 40.22%
    Clove 39.78%
    Mild 38.35%
    Phenolic 37.06%
    Smoky 34.85%
    Powdery 34.65%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    1.3

    pKa est.
    10.63 (weak base)

    Molecular weight
    196.24 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    337°C

    Flash point

    • 145.15 ˚C est.

  • Synonyms

    • 39728-80-8
    • Zingerol
    • EINECS 254-607-2
    • UNII-UP8AC5PTXX
    • UP8AC5PTXX
    • Benzenepropanol, 4-hydroxy-3-methoxy-.alpha.-methyl-
    • 4-HYDROXY-3-METHOXY-.ALPHA.-METHYLBENZENEPROPANOL
    • RefChem:196095
    • ZINGEROL, (+-)-
    • benzenepropanol, 4-hydroxy-3-methoxy-alpha-methyl-
    • 4-HYDROXY-3-METHOXY-ALPHA-METHYLBENZENEPROPANOL
    • 254-607-2
    • GTLGHKNKLRZSMO-UHFFFAOYSA-N
    • 4-(3-hydroxybutyl)-2-methoxyphenol
    • MFCD17168272
    • 4-(3-Hydroxybut-1-yl)-2-methoxyphenol
    • 4-(4-hydroxy-3-methoxyphenyl)-2-butanol
    • 4-(4-Hydroxy-3-methoxyphenyl)butan-2-ol
    • SCHEMBL1259085
    • SCHEMBL8946856
    • SCHEMBL29383461
    • ZINGEROL, (+/-)-
    • DTXSID40960331
    • CHEBI:169651
    • 4-(3-hydroxybutyl)-2-methoxy-phenol
    • AKOS014313543
    • BT-0022
    • CS-0353981
    • NS00057648
    • EN300-1853422
    • Q27291185
    • 39728-80-8

  • Applications

    Zingerol (CAS 39728-80-8) is used primarily as a fragrance ingredient and odorant in perfumery, with potential as a flavor component in limited applications; in cosmetics and personal care, it can contribute to scent profiles; in household products, it may be included to impart fragrance; it can also serve as an intermediate or precursor in the synthesis of related aroma compounds for industrial manufacturing, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 871.37
    methanol 1202.93
    isopropanol 519.12
    water 1.63
    ethyl acetate 417.31
    n-propanol 500.85
    acetone 527.08
    n-butanol 309.22
    acetonitrile 290.47
    DMF 479.08
    toluene 24.12
    isobutanol 245.89
    1,4-dioxane 676.21
    methyl acetate 420.4
    THF 688.27
    2-butanone 269.72
    n-pentanol 190.34
    sec-butanol 268.83
    n-hexane 1.73
    ethylene glycol 474.25
    NMP 160.2
    cyclohexane 3.74
    DMSO 1170.93
    n-butyl acetate 133.12
    n-octanol 65.74
    chloroform 149.17
    n-propyl acetate 153.81
    acetic acid 684.16
    dichloromethane 149.44
    cyclohexanone 238.97
    propylene glycol 669.84
    isopropyl acetate 148.41
    DMAc 347.91
    2-ethoxyethanol 618.23
    isopentanol 202.11
    n-heptane 2.64
    ethyl formate 233.29
    1,2-dichloroethane 134.22
    n-hexanol 180.37
    2-methoxyethanol 1195.94
    isobutyl acetate 89.52
    tetrachloromethane 19.45
    n-pentyl acetate 56.79
    transcutol 778.78
    n-heptanol 69.75
    ethylbenzene 20.81
    MIBK 120.19
    2-propoxyethanol 402.11
    tert-butanol 878.78
    MTBE 249.26
    2-butoxyethanol 160.24
    propionic acid 381.15
    o-xylene 26.39
    formic acid 405.33
    diethyl ether 127.6
    m-xylene 33.22
    p-xylene 25.56
    chlorobenzene 46.16
    dimethyl carbonate 93.18
    n-octane 2.41
    formamide 617.77
    cyclopentanone 330.8
    2-pentanone 200.9
    anisole 106.76
    cyclopentyl methyl ether 161.17
    gamma-butyrolactone 434.58
    1-methoxy-2-propanol 661.19
    pyridine 142.61
    3-pentanone 91.84
    furfural 312.09
    n-dodecane 3.13
    diethylene glycol 534.47
    diisopropyl ether 29.21
    tert-amyl alcohol 400.5
    acetylacetone 299.67
    n-hexadecane 3.41
    acetophenone 96.83
    methyl propionate 242.78
    isopentyl acetate 123.74
    trichloroethylene 263.97
    n-nonanol 57.01
    cyclohexanol 164.76
    benzyl alcohol 125.25
    2-ethylhexanol 71.76
    isooctanol 56.95
    dipropyl ether 44.52
    1,2-dichlorobenzene 51.7
    ethyl lactate 111.37
    propylene carbonate 213.91
    n-methylformamide 423.92
    2-pentanol 148.99
    n-pentane 1.41
    1-propoxy-2-propanol 215.78
    1-methoxy-2-propyl acetate 173.62
    2-(2-methoxypropoxy) propanol 160.49
    mesitylene 21.24
    ε-caprolactone 225.59
    p-cymene 20.24
    epichlorohydrin 511.64
    1,1,1-trichloroethane 101.89
    2-aminoethanol 675.32
    morpholine-4-carbaldehyde 372.17
    sulfolane 415.26
    2,2,4-trimethylpentane 4.38
    2-methyltetrahydrofuran 327.47
    n-hexyl acetate 90.88
    isooctane 4.13
    2-(2-butoxyethoxy)ethanol 239.7
    sec-butyl acetate 83.2
    tert-butyl acetate 175.86
    decalin 4.81
    glycerin 709.77
    diglyme 408.18
    acrylic acid 281.66
    isopropyl myristate 36.98
    n-butyric acid 426.99
    acetyl acetate 169.18
    di(2-ethylhexyl) phthalate 46.57
    ethyl propionate 110.86
    nitromethane 923.99
    1,2-diethoxyethane 147.23
    benzonitrile 93.12
    trioctyl phosphate 36.61
    1-bromopropane 38.17
    gamma-valerolactone 480.01
    n-decanol 44.98
    triethyl phosphate 48.68
    4-methyl-2-pentanol 83.22
    propionitrile 149.25
    vinylene carbonate 175.07
    1,1,2-trichlorotrifluoroethane 364.79
    DMS 90.38
    cumene 19.99
    2-octanol 42.31
    2-hexanone 115.27
    octyl acetate 49.07
    limonene 28.43
    1,2-dimethoxyethane 541.56
    ethyl orthosilicate 45.54
    tributyl phosphate 43.37
    diacetone alcohol 300.54
    N,N-dimethylaniline 60.32
    acrylonitrile 215.12
    aniline 93.56
    1,3-propanediol 779.71
    bromobenzene 37.81
    dibromomethane 75.36
    1,1,2,2-tetrachloroethane 198.58
    2-methyl-cyclohexyl acetate 73.44
    tetrabutyl urea 54.65
    diisobutyl methanol 43.65
    2-phenylethanol 114.47
    styrene 24.07
    dioctyl adipate 60.96
    dimethyl sulfate 147.96
    ethyl butyrate 85.05
    methyl lactate 195.33
    butyl lactate 74.49
    diethyl carbonate 63.28
    propanediol butyl ether 193.33
    triethyl orthoformate 58.56
    p-tert-butyltoluene 22.02
    methyl 4-tert-butylbenzoate 92.48
    morpholine 795.99
    tert-butylamine 241.74
    n-dodecanol 35.51
    dimethoxymethane 349.57
    ethylene carbonate 159.39
    cyrene 140.02
    2-ethoxyethyl acetate 121.37
    2-ethylhexyl acetate 75.51
    1,2,4-trichlorobenzene 68.17
    4-methylpyridine 125.82
    dibutyl ether 46.64
    2,6-dimethyl-4-heptanol 43.65
    DEF 166.0
    dimethyl isosorbide 213.3
    tetrachloroethylene 124.39
    eugenol 109.12
    triacetin 112.36
    span 80 125.14
    1,4-butanediol 281.54
    1,1-dichloroethane 116.62
    2-methyl-1-pentanol 134.02
    methyl formate 345.16
    2-methyl-1-butanol 167.15
    n-decane 4.35
    butyronitrile 150.81
    3,7-dimethyl-1-octanol 66.38
    1-chlorooctane 23.25
    1-chlorotetradecane 10.82
    n-nonane 3.79
    undecane 3.61
    tert-butylcyclohexane 5.66
    cyclooctane 1.96
    cyclopentanol 226.58
    tetrahydropyran 298.82
    tert-amyl methyl ether 135.89
    2,5,8-trioxanonane 284.71
    1-hexene 12.96
    2-isopropoxyethanol 318.79
    2,2,2-trifluoroethanol 194.65
    methyl butyrate 161.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction