Zilpaterol Hydrochloride

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  • Identifiers

    CAS number
    119520-06-8

    Molecular formula
    C14H20ClN3O2

    SMILES
    CC(C)N[C@@H]1CCN2C3=C([C@H]1O)C=CC=C3NC2=O.Cl

    Safety labels

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 73.15%
    Savory 26.86%
    Roasted 22.94%
    Cooling 21.83%
    Meaty 21.5%
    Fishy 20.37%
    Cooked 19.51%
    Burnt 19.19%
    Animal 18.95%
    Bitter 18.26%

     

    Flavor
    Bitter 83.91%
    Odorless 29.46%
    Bland 22.55%
    Cedarleaf 20.81%
    Sweet-like 20.31%
    Nitrile 19.51%
    Lovage 18.35%
    Very strong 18.26%
    Green pepper 18.2%
    Alkaline 18.13%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    7.58 (neutral)

    Molecular weight
    297.78 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    674°C

    Flash point

    • 240.97 ˚C est.

  • Synonyms

    • Zilpaterol hydrochloride
    • 119520-06-8
    • Zilpaterol HCl
    • UNII-EX8IEP25JU
    • Zilmax
    • EX8IEP25JU
    • Imidazo(4,5,1-jk)(1)benzazepin-2(1h)-one, 4,5,6,7-tetrahydro-7-hydroxy-6-((1-methylethyl)amino)-, monohydrochloride
    • Rac-(6R,7R)-7-hydroxy-6-(isopropylamino)-4,5,6,7-tetrahydroimidazo(4,5,1-jk)(1)benzazepin-2(1h)-one hydrochloride
    • ZILPATEROL HYDROCHLORIDE (MART.)
    • ZILPATEROL HYDROCHLORIDE [MART.]
    • RefChem:56614
    • MFCD09033213
    • (9R,10R)-9-hydroxy-10-(propan-2-ylamino)-1,3-diazatricyclo[6.4.1.04,13]trideca-4,6,8(13)-trien-2-one;hydrochloride
    • 9-Hydroxy-10-(propan-2-ylamino)-1,3-diazatricyclo[6.4.1.04,13]trideca-4,6,8(13)-trien-2-one;hydrochloride
    • trans-(+)-Zilpaterol (hydrochloride)
    • 1044281-58-4
    • 1117752-22-3
    • Zilpaterol hydrochloride (relstereo)
    • SCHEMBL135498
    • CHEMBL513390
    • MSK1326A
    • SCHEMBL29579406
    • (+/1)-trans-4,5,6,7-Tetrahydro-7-hydroxy-6-(isopropylamino)imidazo[4,5,1-jk]-[1]benzazepin-2(1H)-one hydrochloride
    • Imidazo[4,5,1-jk][1]benzazepin-2(1H)-one, 4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]-, (Hydrochloride) (1:1), (6R,7R)-
    • ZILPATEROL HYDROCHLORIDE [MI]
    • AKOS015967220
    • FZ175003
    • ZILPATEROL HYDROCHLORIDE [GREEN BOOK]
    • F94045
    • 520Z068
    • Q27277408
    • (9R,10R)-9-hydroxy-10-(isopropylamino)-1,3-diazatricyclo[6.4.1.04,13]trideca-4,6,8(13)-trien-2-one;hydrochloride
    • (9R,10R)-9-hydroxy-10-[(propan-2-yl)amino]-1,3-diazatricyclo[6.4.1.0?,??]trideca-4,6,8(13)-trien-2-one hydrochloride
    • 119520-06-8

  • Applications

    Zilpaterol Hydrochloride (CAS 119520-06-8) is a beta-adrenergic agonist primarily used in agriculture as a repartitioning feed additive to promote lean muscle growth and improve feed efficiency in cattle and other livestock; in veterinary medicine, it is used as a veterinary drug under controlled dosing to optimize growth performance; in animal nutrition research, it is evaluated for efficacy, dosage, and residue behavior; its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 9.07
    methanol 21.85
    isopropanol 4.88
    water 3.7
    ethyl acetate 4.16
    n-propanol 7.72
    acetone 5.16
    n-butanol 7.0
    acetonitrile 1.39
    DMF 96.56
    toluene 0.24
    isobutanol 6.47
    1,4-dioxane 5.22
    methyl acetate 4.96
    THF 17.68
    2-butanone 6.96
    n-pentanol 7.4
    sec-butanol 4.65
    n-hexane 0.07
    ethylene glycol 31.28
    NMP 91.95
    cyclohexane 0.05
    DMSO 107.87
    n-butyl acetate 9.72
    n-octanol 3.25
    chloroform 6.77
    n-propyl acetate 6.3
    acetic acid 46.1
    dichloromethane 6.19
    cyclohexanone 15.53
    propylene glycol 23.07
    isopropyl acetate 3.97
    DMAc 122.09
    2-ethoxyethanol 34.77
    isopentanol 7.92
    n-heptane 0.09
    ethyl formate 8.58
    1,2-dichloroethane 4.47
    n-hexanol 7.39
    2-methoxyethanol 63.66
    isobutyl acetate 6.56
    tetrachloromethane 1.2
    n-pentyl acetate 8.14
    transcutol 31.16
    n-heptanol 5.92
    ethylbenzene 0.37
    MIBK 5.97
    2-propoxyethanol 43.46
    tert-butanol 4.74
    MTBE 1.26
    2-butoxyethanol 26.22
    propionic acid 18.01
    o-xylene 0.43
    formic acid 91.61
    diethyl ether 0.96
    m-xylene 0.52
    p-xylene 0.76
    chlorobenzene 1.34
    dimethyl carbonate 8.35
    n-octane 0.08
    formamide 72.64
    cyclopentanone 28.41
    2-pentanone 6.12
    anisole 1.62
    cyclopentyl methyl ether 3.72
    gamma-butyrolactone 40.71
    1-methoxy-2-propanol 36.49
    pyridine 5.08
    3-pentanone 4.05
    furfural 45.82
    n-dodecane 0.1
    diethylene glycol 65.77
    diisopropyl ether 0.5
    tert-amyl alcohol 5.38
    acetylacetone 10.43
    n-hexadecane 0.12
    acetophenone 6.02
    methyl propionate 7.46
    isopentyl acetate 10.86
    trichloroethylene 11.56
    n-nonanol 3.61
    cyclohexanol 3.75
    benzyl alcohol 6.92
    2-ethylhexanol 4.09
    isooctanol 5.42
    dipropyl ether 1.52
    1,2-dichlorobenzene 2.47
    ethyl lactate 14.29
    propylene carbonate 22.18
    n-methylformamide 39.25
    2-pentanol 3.2
    n-pentane 0.05
    1-propoxy-2-propanol 22.8
    1-methoxy-2-propyl acetate 16.61
    2-(2-methoxypropoxy) propanol 19.74
    mesitylene 0.46
    ε-caprolactone 19.65
    p-cymene 1.06
    epichlorohydrin 27.86
    1,1,1-trichloroethane 2.54
    2-aminoethanol 32.04
    morpholine-4-carbaldehyde 72.99
    sulfolane 81.78
    2,2,4-trimethylpentane 0.09
    2-methyltetrahydrofuran 6.26
    n-hexyl acetate 7.43
    isooctane 0.07
    2-(2-butoxyethoxy)ethanol 22.97
    sec-butyl acetate 3.91
    tert-butyl acetate 4.57
    decalin 0.1
    glycerin 69.97
    diglyme 32.89
    acrylic acid 25.98
    isopropyl myristate 2.9
    n-butyric acid 21.07
    acetyl acetate 4.01
    di(2-ethylhexyl) phthalate 8.91
    ethyl propionate 4.72
    nitromethane 47.47
    1,2-diethoxyethane 5.51
    benzonitrile 5.33
    trioctyl phosphate 6.48
    1-bromopropane 1.24
    gamma-valerolactone 59.82
    n-decanol 2.73
    triethyl phosphate 6.39
    4-methyl-2-pentanol 3.17
    propionitrile 2.27
    vinylene carbonate 20.65
    1,1,2-trichlorotrifluoroethane 58.7
    DMS 10.74
    cumene 0.63
    2-octanol 3.31
    2-hexanone 6.02
    octyl acetate 4.77
    limonene 1.19
    1,2-dimethoxyethane 21.51
    ethyl orthosilicate 5.25
    tributyl phosphate 6.91
    diacetone alcohol 15.85
    N,N-dimethylaniline 2.26
    acrylonitrile 5.31
    aniline 1.84
    1,3-propanediol 34.44
    bromobenzene 0.95
    dibromomethane 2.69
    1,1,2,2-tetrachloroethane 10.48
    2-methyl-cyclohexyl acetate 7.7
    tetrabutyl urea 9.59
    diisobutyl methanol 2.11
    2-phenylethanol 9.09
    styrene 0.37
    dioctyl adipate 6.23
    dimethyl sulfate 30.8
    ethyl butyrate 5.62
    methyl lactate 23.53
    butyl lactate 16.82
    diethyl carbonate 5.11
    propanediol butyl ether 23.01
    triethyl orthoformate 5.52
    p-tert-butyltoluene 0.98
    methyl 4-tert-butylbenzoate 12.05
    morpholine 10.82
    tert-butylamine 1.24
    n-dodecanol 1.99
    dimethoxymethane 18.79
    ethylene carbonate 15.18
    cyrene 31.34
    2-ethoxyethyl acetate 13.79
    2-ethylhexyl acetate 7.51
    1,2,4-trichlorobenzene 3.8
    4-methylpyridine 3.63
    dibutyl ether 1.42
    2,6-dimethyl-4-heptanol 2.11
    DEF 14.11
    dimethyl isosorbide 29.37
    tetrachloroethylene 7.63
    eugenol 19.86
    triacetin 11.52
    span 80 16.63
    1,4-butanediol 21.75
    1,1-dichloroethane 2.24
    2-methyl-1-pentanol 7.64
    methyl formate 25.4
    2-methyl-1-butanol 7.28
    n-decane 0.14
    butyronitrile 2.79
    3,7-dimethyl-1-octanol 3.61
    1-chlorooctane 0.8
    1-chlorotetradecane 0.42
    n-nonane 0.11
    undecane 0.12
    tert-butylcyclohexane 0.11
    cyclooctane 0.03
    cyclopentanol 7.81
    tetrahydropyran 2.41
    tert-amyl methyl ether 1.7
    2,5,8-trioxanonane 25.32
    1-hexene 0.37
    2-isopropoxyethanol 20.63
    2,2,2-trifluoroethanol 37.19
    methyl butyrate 8.0

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction