(Z)-Tetradec-5-en-14-olide

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  • Identifiers

    CAS number
    77761-59-2

    SMILES
    O=C1CCC\C=C/CCCCCCCCO1

  • Odor profile

    Musk 87.29%
    Sweet 73.98%
    Fruity 63.16%
    Animal 59.05%
    Powdery 55.72%
    Waxy 55.34%
    Amber 47.26%
    Fatty 39.47%
    Dry 34.95%
    Balsamic 34.19%

    Scent© AI

  • Properties

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    306°C

    Flash point est.
    149.51 ˚C

  • Applications

    (Z)-Tetradec-5-en-14-olide (CAS 77761-59-2) is a macrocyclic lactone with a clean ambrette-musky odour, used mainly in perfumery as a substantive musk note and fixative for fine fragrances, personal care, and functional scents (soaps, detergents, fabric care), enhancing diffusion, bloom, and longevity while adding creamy, clean floral-fruity nuances; it is also employed as a reference standard and research scaffold in structure-odor studies, macrocyclic lactone synthesis, and insect semiochemical/pheromone investigations, as well as in testing fragrance encapsulation and delivery systems due to its hydrophobicity and relative stability.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1357.19
    methanol 1181.5
    isopropanol 1244.39
    water 0.05
    ethyl acetate 1805.0
    n-propanol 1157.94
    acetone 2429.32
    n-butanol 1151.35
    acetonitrile 1277.57
    DMF 2172.4
    toluene 1164.76
    isobutanol 929.91
    1,4-dioxane 2140.31
    methyl acetate 1074.93
    THF 3174.08
    2-butanone 1647.16
    n-pentanol 793.06
    sec-butanol 1065.19
    n-hexane 451.81
    ethylene glycol 126.9
    NMP 1693.24
    cyclohexane 720.46
    DMSO 2863.19
    n-butyl acetate 1335.35
    n-octanol 369.03
    chloroform 4089.48
    n-propyl acetate 1127.44
    acetic acid 1215.31
    dichloromethane 3755.28
    cyclohexanone 2569.68
    propylene glycol 282.09
    isopropyl acetate 1224.18
    DMAc 1512.55
    2-ethoxyethanol 899.72
    isopentanol 1093.82
    n-heptane 179.73
    ethyl formate 745.11
    1,2-dichloroethane 2585.83
    n-hexanol 804.36
    2-methoxyethanol 1371.15
    isobutyl acetate 740.51
    tetrachloromethane 561.42
    n-pentyl acetate 890.91
    transcutol 4919.3
    n-heptanol 348.17
    ethylbenzene 525.89
    MIBK 1057.37
    2-propoxyethanol 1157.71
    tert-butanol 1394.39
    MTBE 1609.45
    2-butoxyethanol 703.3
    propionic acid 883.1
    o-xylene 559.96
    formic acid 224.85
    diethyl ether 2225.88
    m-xylene 664.38
    p-xylene 585.43
    chlorobenzene 1353.63
    dimethyl carbonate 418.5
    n-octane 60.6
    formamide 392.02
    cyclopentanone 2558.35
    2-pentanone 1714.79
    anisole 855.57
    cyclopentyl methyl ether 1805.13
    gamma-butyrolactone 2344.01
    1-methoxy-2-propanol 1233.05
    pyridine 2538.01
    3-pentanone 1185.81
    furfural 1780.88
    n-dodecane 40.7
    diethylene glycol 618.25
    diisopropyl ether 625.51
    tert-amyl alcohol 1084.15
    acetylacetone 1559.24
    n-hexadecane 48.66
    acetophenone 756.06
    methyl propionate 1085.56
    isopentyl acetate 1097.02
    trichloroethylene 4079.38
    n-nonanol 326.1
    cyclohexanol 1285.48
    benzyl alcohol 645.07
    2-ethylhexanol 540.14
    isooctanol 316.35
    dipropyl ether 918.37
    1,2-dichlorobenzene 1132.3
    ethyl lactate 372.48
    propylene carbonate 1219.11
    n-methylformamide 847.73
    2-pentanol 971.23
    n-pentane 327.29
    1-propoxy-2-propanol 970.82
    1-methoxy-2-propyl acetate 1035.42
    2-(2-methoxypropoxy) propanol 694.74
    mesitylene 425.11
    ε-caprolactone 1856.15
    p-cymene 272.24
    epichlorohydrin 2579.02
    1,1,1-trichloroethane 2042.13
    2-aminoethanol 404.5
    morpholine-4-carbaldehyde 1582.34
    sulfolane 2495.77
    2,2,4-trimethylpentane 124.81
    2-methyltetrahydrofuran 2453.52
    n-hexyl acetate 1071.05
    isooctane 115.34
    2-(2-butoxyethoxy)ethanol 1118.14
    sec-butyl acetate 796.07
    tert-butyl acetate 1176.58
    decalin 229.18
    glycerin 375.04
    diglyme 1987.43
    acrylic acid 663.26
    isopropyl myristate 361.69
    n-butyric acid 1579.17
    acetyl acetate 955.21
    di(2-ethylhexyl) phthalate 310.91
    ethyl propionate 912.91
    nitromethane 1779.73
    1,2-diethoxyethane 1675.0
    benzonitrile 1025.75
    trioctyl phosphate 220.92
    1-bromopropane 1877.75
    gamma-valerolactone 2420.52
    n-decanol 230.92
    triethyl phosphate 335.15
    4-methyl-2-pentanol 520.0
    propionitrile 1176.89
    vinylene carbonate 1041.25
    1,1,2-trichlorotrifluoroethane 1556.2
    DMS 734.28
    cumene 318.42
    2-octanol 272.43
    2-hexanone 1087.56
    octyl acetate 449.96
    limonene 465.12
    1,2-dimethoxyethane 1642.03
    ethyl orthosilicate 337.44
    tributyl phosphate 309.66
    diacetone alcohol 1018.8
    N,N-dimethylaniline 541.0
    acrylonitrile 1247.9
    aniline 1189.05
    1,3-propanediol 721.31
    bromobenzene 1643.07
    dibromomethane 2739.77
    1,1,2,2-tetrachloroethane 3341.24
    2-methyl-cyclohexyl acetate 600.88
    tetrabutyl urea 390.22
    diisobutyl methanol 343.64
    2-phenylethanol 585.03
    styrene 777.56
    dioctyl adipate 538.38
    dimethyl sulfate 651.35
    ethyl butyrate 845.88
    methyl lactate 463.79
    butyl lactate 586.29
    diethyl carbonate 529.72
    propanediol butyl ether 689.2
    triethyl orthoformate 568.82
    p-tert-butyltoluene 266.81
    methyl 4-tert-butylbenzoate 641.47
    morpholine 2595.75
    tert-butylamine 989.69
    n-dodecanol 175.39
    dimethoxymethane 1298.45
    ethylene carbonate 978.44
    cyrene 513.24
    2-ethoxyethyl acetate 1089.33
    2-ethylhexyl acetate 847.38
    1,2,4-trichlorobenzene 1234.93
    4-methylpyridine 2154.54
    dibutyl ether 881.4
    2,6-dimethyl-4-heptanol 343.64
    DEF 1617.47
    dimethyl isosorbide 1034.9
    tetrachloroethylene 2211.6
    eugenol 576.54
    triacetin 929.31
    span 80 698.95
    1,4-butanediol 265.27
    1,1-dichloroethane 2489.59
    2-methyl-1-pentanol 725.26
    methyl formate 558.67
    2-methyl-1-butanol 965.74
    n-decane 79.25
    butyronitrile 1451.92
    3,7-dimethyl-1-octanol 443.75
    1-chlorooctane 367.09
    1-chlorotetradecane 124.97
    n-nonane 82.05
    undecane 53.99
    tert-butylcyclohexane 180.77
    cyclooctane 209.73
    cyclopentanol 1184.14
    tetrahydropyran 3065.94
    tert-amyl methyl ether 1038.75
    2,5,8-trioxanonane 1182.73
    1-hexene 1113.02
    2-isopropoxyethanol 757.18
    2,2,2-trifluoroethanol 312.59
    methyl butyrate 1215.79

    Scent© AI

1 3

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Ambrette seed 1 8015-62-1 Hibiscus abelmoschus L. (Abelmoschus moschatus Moench), fam. Malvaceae 1.08%
Ambrette seed 2 8015-62-1 Hibiscus abelmoschus L. (Abelmoschus moschatus Moench), fam. Malvaceae 1.8%
Ambrette seed 4 8015-62-1 Hibiscus abelmoschus L. (Abelmoschus moschatus Moench), fam. Malvaceae 0.4%
Ambrette seed 3 8015-62-1 Hibiscus abelmoschus L. (Abelmoschus moschatus Moench), fam. Malvaceae 0.7%