Villosol

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  • Identifiers

    CAS number
    60077-62-5

    Molecular formula
    C23H20O7

    SMILES
    CC(=C)[C@H]1CC2=C(O1)C=C(C3=C2OC4=C(C3=O)C5=CC(=C(C=C5OC4)OC)OC)O

    Safety labels

  • Odor profile

    Fragrance
    Spicy 41.8%
    Phenolic 37.2%
    Sweet 33.66%
    Woody 30.75%
    Vanilla 27.88%
    Fruity 26.5%
    Powdery 25.95%
    Odorless 24.95%
    Dry 22.69%
    Burnt 22.67%

     

    Flavor
    Bitter 92.75%
    Bland 21.39%
    Parsley 19.75%
    Cedarleaf 19.5%
    Lovage 18.85%
    Sweet-like 18.39%
    Ripe apricot 17.68%
    Red fruit 17.36%
    Eugenol 17.32%
    Carrot 17.27%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.2

    pKa est.
    8.28 (weak base)

    Molecular weight
    408.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    998°C

    Flash point

    • 245.93 ˚C est.

  • Synonyms

    • Villosol
    • 60077-62-5
    • DTXSID90208816
    • (6R)-10-Hydroxy-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-1(13),3(11),4(8),9,14,16,18-heptaen-12-one
    • (6R)-10-hydroxy-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo(11.8.0.03,11.04,8.014,19)henicosa-1(13),3(11),4(8),9,14,16,18-heptaen-12-one
    • RefChem:194251
    • DTXCID40131307
    • 10-hydroxy-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo(11.8.0.03,11.04,8.014,19)henicosa-1(13),3(11),4(8),9,14,16,18-heptaen-12-one
    • orb1684049
    • AKOS040760850
    • AC-34028
    • (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(12H)-one, 1,2,-dihydro-5-hydroxy-8,9-dimethoxy-2-(1-methylethenyl)-, (R)-
    • (2R)-5-Hydroxy-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2-dihydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(12H)-one
    • 60077-62-5

  • Applications

    Villosol (CAS 60077-62-5) is often viewed as a solvent and carrier in a range of industrial and personal care formulations. In the fragrance and cosmetics sectors, it may serve as a solvent to dissolve fragrance ingredients and can be considered a light fixative or odorant. In coatings and inks, Villosol can be used as a solvent or processing aid to improve evaporation control and flow properties. In polymers or plastics, it may function as a plasticizer or stabilizer in certain formulations. It is also considered for cleaning formulations as a solvent, with use governed by local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.49
    methanol 0.65
    isopropanol 0.92
    water 0.0
    ethyl acetate 10.68
    n-propanol 0.88
    acetone 13.44
    n-butanol 1.01
    acetonitrile 7.22
    DMF 24.14
    toluene 1.82
    isobutanol 1.1
    1,4-dioxane 11.94
    methyl acetate 15.22
    THF 23.78
    2-butanone 14.59
    n-pentanol 0.89
    sec-butanol 1.01
    n-hexane 0.02
    ethylene glycol 0.83
    NMP 44.98
    cyclohexane 0.08
    DMSO 37.17
    n-butyl acetate 7.14
    n-octanol 0.83
    chloroform 32.25
    n-propyl acetate 8.11
    acetic acid 19.37
    dichloromethane 28.14
    cyclohexanone 25.98
    propylene glycol 0.63
    isopropyl acetate 7.32
    DMAc 55.25
    2-ethoxyethanol 5.39
    isopentanol 1.56
    n-heptane 0.04
    ethyl formate 7.41
    1,2-dichloroethane 13.58
    n-hexanol 0.97
    2-methoxyethanol 7.73
    isobutyl acetate 5.73
    tetrachloromethane 1.87
    n-pentyl acetate 6.06
    transcutol 18.27
    n-heptanol 1.11
    ethylbenzene 0.76
    MIBK 5.88
    2-propoxyethanol 9.48
    tert-butanol 1.77
    MTBE 1.63
    2-butoxyethanol 6.44
    propionic acid 7.2
    o-xylene 1.25
    formic acid 4.67
    diethyl ether 1.71
    m-xylene 1.06
    p-xylene 1.53
    chlorobenzene 5.22
    dimethyl carbonate 14.37
    n-octane 0.03
    formamide 7.66
    cyclopentanone 33.97
    2-pentanone 8.88
    anisole 3.52
    cyclopentyl methyl ether 4.94
    gamma-butyrolactone 44.36
    1-methoxy-2-propanol 6.28
    pyridine 15.03
    3-pentanone 9.0
    furfural 36.55
    n-dodecane 0.05
    diethylene glycol 9.68
    diisopropyl ether 0.57
    tert-amyl alcohol 1.7
    acetylacetone 22.29
    n-hexadecane 0.06
    acetophenone 8.63
    methyl propionate 11.9
    isopentyl acetate 7.9
    trichloroethylene 52.87
    n-nonanol 1.14
    cyclohexanol 2.3
    benzyl alcohol 4.45
    2-ethylhexanol 1.24
    isooctanol 1.31
    dipropyl ether 1.7
    1,2-dichlorobenzene 6.21
    ethyl lactate 6.22
    propylene carbonate 20.33
    n-methylformamide 8.15
    2-pentanol 0.77
    n-pentane 0.03
    1-propoxy-2-propanol 6.76
    1-methoxy-2-propyl acetate 15.05
    2-(2-methoxypropoxy) propanol 10.95
    mesitylene 0.6
    ε-caprolactone 21.82
    p-cymene 1.14
    epichlorohydrin 42.13
    1,1,1-trichloroethane 12.17
    2-aminoethanol 0.93
    morpholine-4-carbaldehyde 37.52
    sulfolane 60.24
    2,2,4-trimethylpentane 0.05
    2-methyltetrahydrofuran 8.47
    n-hexyl acetate 5.38
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 9.74
    sec-butyl acetate 5.37
    tert-butyl acetate 7.42
    decalin 0.08
    glycerin 3.32
    diglyme 23.8
    acrylic acid 10.95
    isopropyl myristate 2.94
    n-butyric acid 8.35
    acetyl acetate 15.09
    di(2-ethylhexyl) phthalate 5.17
    ethyl propionate 7.62
    nitromethane 53.24
    1,2-diethoxyethane 5.96
    benzonitrile 8.23
    trioctyl phosphate 3.08
    1-bromopropane 2.72
    gamma-valerolactone 54.23
    n-decanol 0.87
    triethyl phosphate 6.21
    4-methyl-2-pentanol 0.86
    propionitrile 5.62
    vinylene carbonate 22.85
    1,1,2-trichlorotrifluoroethane 45.94
    DMS 13.48
    cumene 0.64
    2-octanol 0.68
    2-hexanone 7.24
    octyl acetate 3.68
    limonene 1.28
    1,2-dimethoxyethane 13.71
    ethyl orthosilicate 4.83
    tributyl phosphate 4.24
    diacetone alcohol 11.07
    N,N-dimethylaniline 2.61
    acrylonitrile 11.86
    aniline 4.59
    1,3-propanediol 2.38
    bromobenzene 4.83
    dibromomethane 10.65
    1,1,2,2-tetrachloroethane 31.48
    2-methyl-cyclohexyl acetate 7.51
    tetrabutyl urea 6.39
    diisobutyl methanol 1.07
    2-phenylethanol 5.52
    styrene 1.03
    dioctyl adipate 6.52
    dimethyl sulfate 30.65
    ethyl butyrate 6.73
    methyl lactate 9.68
    butyl lactate 6.33
    diethyl carbonate 6.36
    propanediol butyl ether 4.09
    triethyl orthoformate 5.97
    p-tert-butyltoluene 0.94
    methyl 4-tert-butylbenzoate 10.33
    morpholine 11.66
    tert-butylamine 0.6
    n-dodecanol 0.68
    dimethoxymethane 13.86
    ethylene carbonate 18.25
    cyrene 15.64
    2-ethoxyethyl acetate 12.55
    2-ethylhexyl acetate 6.16
    1,2,4-trichlorobenzene 10.22
    4-methylpyridine 12.34
    dibutyl ether 1.57
    2,6-dimethyl-4-heptanol 1.07
    DEF 13.15
    dimethyl isosorbide 23.72
    tetrachloroethylene 17.03
    eugenol 9.79
    triacetin 13.43
    span 80 6.73
    1,4-butanediol 1.07
    1,1-dichloroethane 9.64
    2-methyl-1-pentanol 1.47
    methyl formate 10.92
    2-methyl-1-butanol 1.37
    n-decane 0.07
    butyronitrile 3.84
    3,7-dimethyl-1-octanol 1.43
    1-chlorooctane 0.59
    1-chlorotetradecane 0.32
    n-nonane 0.05
    undecane 0.06
    tert-butylcyclohexane 0.06
    cyclooctane 0.03
    cyclopentanol 2.77
    tetrahydropyran 5.59
    tert-amyl methyl ether 1.69
    2,5,8-trioxanonane 18.13
    1-hexene 0.18
    2-isopropoxyethanol 4.9
    2,2,2-trifluoroethanol 11.84
    methyl butyrate 9.98

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction