Veratric Acid

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    93-07-2

    Molecular formula
    C9H10O4

    SMILES
    COC1=C(C=C(C=C1)C(=O)O)OC

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Vanilla 77.54%
    Sweet 76.89%
    Balsamic 56.28%
    Phenolic 53.09%
    Powdery 52.98%
    Creamy 52.52%
    Floral 51.3%
    Spicy 43.31%
    Aromatic 37.0%
    Woody 36.05%

    Scent© AI

  • Properties

    XLogP3-AA
    1.6

    Molecular weight
    182.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    334°C

    Flash point est.
    140.49 ˚C

  • Synonyms

    • 3,4-Dimethoxybenzoic acid
    • VERATRIC ACID
    • 93-07-2
    • Benzoic acid, 3,4-dimethoxy-
    • Dimethylprotocatechuic acid
    • Veratrylic acid
    • Veratrumenoic acid
    • 3,4-Dimethylprotocatechuic acid
    • 3,4-Dimethoxy-benzoic acid
    • MFCD00002500
    • NSC 7721
    • CHEBI:296881
    • 3,4-Dimethoxybenzoic acid (Veratric acid)
    • EINECS 202-215-7
    • BRN 0518285
    • 1YY04E7RR4
    • NSC-7721
    • VERATRIC ACID [MI]
    • CHEMBL118903
    • DTXSID6059077
    • EC 202-215-7
    • 3,?4-?Dimethoxybenzoic Acid (Veratric Acid)
    • MEBEVERINE HYDROCHLORIDE IMPURITY D [EP IMPURITY]
    • 3,4-Dimethoxybenzoicacid
    • MEBEVERINE HYDROCHLORIDE IMPURITY D (EP IMPURITY)
    • UNII-1YY04E7RR4
    • 3,4-Dimethoxybenzoic Acid; Mebeverine Hydrochloride Imp. D (Pharmeuropa); Veratric Acid; Mebeverine Hydrochloride Impurity D; Mebeverine Impurity D
    • TWO
    • Spectrum_000512
    • 3,4dimethoxybenzoic acid
    • Spectrum2_001082
    • Spectrum3_001774
    • Spectrum4_001582
    • Spectrum5_000264
    • 3,4 dimethoxybenzoic acid
    • 3,4-dimethoxybenzoic-acid
    • 3,4dimethoxy benzoic acid
    • bmse010207
    • Epitope ID:119695
    • 3,4-Dimethoxy benzoic acid
    • Benzoic acid, 3,4dimethoxy
    • BSPBio_003267
    • KBioGR_002164
    • KBioSS_000992
    • SPECTRUM212140
    • VERATRIC ACID [INCI]
    • MLS002207141
    • SCHEMBL114848
    • 3,4Dimethylprotocatechuic acid
    • SPBio_001124
    • 3,4-bis(methyloxy)benzoic acid
    • DTXCID7048827
    • KBio2_000992
    • KBio2_003560
    • KBio2_006128
    • KBio3_002768
    • NSC7721
    • Protocatechuic Acid Dimethyl Ether
    • HY-N2007
    • BBL025942
    • BDBM50336487
    • CCG-39276
    • STK397279
    • 3,4-Dimethoxybenzoic acid, >=99%
    • AKOS000119433
    • BS-3989
    • FV28690
    • SDCCGMLS-0066972.P001
    • NCGC00095539-01
    • NCGC00095539-02
    • AC-10246
    • SMR000112092
    • SY010549
    • CS-0018327
    • D0631
    • NS00004303
    • EN300-20508
    • D71090
    • AP-163/40806830
    • Q425928
    • SR-05000002417
    • SR-05000002417-1
    • BRD-K14520048-001-02-6
    • BRD-K14520048-001-04-2
    • F2191-0107
    • Z104478452
    • 3,4-Dimethoxybenzoic acid;Dimethylprotocatechuic acid;NSC 7721
    • 202-215-7

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 24.45
    methanol 39.9
    isopropanol 15.77
    water 1.15
    ethyl acetate 18.14
    n-propanol 15.59
    acetone 57.32
    n-butanol 12.12
    acetonitrile 22.31
    DMF 321.89
    toluene 3.88
    isobutanol 8.7
    1,4-dioxane 49.79
    methyl acetate 25.13
    THF 143.78
    2-butanone 29.45
    n-pentanol 12.9
    sec-butanol 15.35
    n-hexane 1.41
    ethylene glycol 27.66
    NMP 298.1
    cyclohexane 1.4
    DMSO 721.73
    n-butyl acetate 32.56
    n-octanol 11.34
    chloroform 32.98
    n-propyl acetate 25.36
    acetic acid 55.73
    dichloromethane 70.67
    cyclohexanone 59.35
    propylene glycol 15.58
    isopropyl acetate 17.05
    DMAc 207.34
    2-ethoxyethanol 68.94
    isopentanol 13.33
    n-heptane 2.15
    ethyl formate 24.45
    1,2-dichloroethane 63.63
    n-hexanol 16.6
    2-methoxyethanol 94.84
    isobutyl acetate 11.29
    tetrachloromethane 8.63
    n-pentyl acetate 19.46
    transcutol 152.44
    n-heptanol 11.08
    ethylbenzene 7.11
    MIBK 20.4
    2-propoxyethanol 56.01
    tert-butanol 37.84
    MTBE 26.53
    2-butoxyethanol 31.85
    propionic acid 30.1
    o-xylene 9.43
    formic acid 69.68
    diethyl ether 18.4
    m-xylene 6.66
    p-xylene 8.46
    chlorobenzene 12.78
    dimethyl carbonate 34.46
    n-octane 0.88
    formamide 198.06
    cyclopentanone 118.1
    2-pentanone 23.61
    anisole 33.23
    cyclopentyl methyl ether 38.08
    gamma-butyrolactone 173.67
    1-methoxy-2-propanol 61.19
    pyridine 33.84
    3-pentanone 22.94
    furfural 158.4
    n-dodecane 0.73
    diethylene glycol 66.42
    diisopropyl ether 7.83
    tert-amyl alcohol 32.3
    acetylacetone 46.88
    n-hexadecane 0.85
    acetophenone 45.16
    methyl propionate 29.28
    isopentyl acetate 27.8
    trichloroethylene 95.61
    n-nonanol 10.79
    cyclohexanol 14.45
    benzyl alcohol 26.04
    2-ethylhexanol 13.26
    isooctanol 9.77
    dipropyl ether 18.2
    1,2-dichlorobenzene 25.22
    ethyl lactate 28.7
    propylene carbonate 68.67
    n-methylformamide 115.01
    2-pentanol 10.72
    n-pentane 1.19
    1-propoxy-2-propanol 38.61
    1-methoxy-2-propyl acetate 47.61
    2-(2-methoxypropoxy) propanol 46.73
    mesitylene 6.57
    ε-caprolactone 60.07
    p-cymene 9.62
    epichlorohydrin 151.25
    1,1,1-trichloroethane 24.69
    2-aminoethanol 30.12
    morpholine-4-carbaldehyde 187.58
    sulfolane 379.3
    2,2,4-trimethylpentane 1.72
    2-methyltetrahydrofuran 60.89
    n-hexyl acetate 26.6
    isooctane 1.04
    2-(2-butoxyethoxy)ethanol 48.34
    sec-butyl acetate 16.27
    tert-butyl acetate 36.51
    decalin 2.21
    glycerin 46.46
    diglyme 122.23
    acrylic acid 42.17
    isopropyl myristate 11.4
    n-butyric acid 24.47
    acetyl acetate 20.48
    di(2-ethylhexyl) phthalate 14.44
    ethyl propionate 23.88
    nitromethane 155.22
    1,2-diethoxyethane 35.97
    benzonitrile 22.92
    trioctyl phosphate 11.41
    1-bromopropane 15.12
    gamma-valerolactone 143.35
    n-decanol 8.18
    triethyl phosphate 29.14
    4-methyl-2-pentanol 8.81
    propionitrile 15.63
    vinylene carbonate 55.82
    1,1,2-trichlorotrifluoroethane 118.75
    DMS 40.71
    cumene 7.82
    2-octanol 7.92
    2-hexanone 23.72
    octyl acetate 14.81
    limonene 13.19
    1,2-dimethoxyethane 110.9
    ethyl orthosilicate 24.83
    tributyl phosphate 14.83
    diacetone alcohol 53.37
    N,N-dimethylaniline 36.09
    acrylonitrile 32.77
    aniline 16.09
    1,3-propanediol 30.41
    bromobenzene 10.84
    dibromomethane 34.04
    1,1,2,2-tetrachloroethane 72.4
    2-methyl-cyclohexyl acetate 30.57
    tetrabutyl urea 22.49
    diisobutyl methanol 10.24
    2-phenylethanol 26.98
    styrene 7.66
    dioctyl adipate 22.97
    dimethyl sulfate 128.87
    ethyl butyrate 29.44
    methyl lactate 39.53
    butyl lactate 22.67
    diethyl carbonate 26.87
    propanediol butyl ether 30.21
    triethyl orthoformate 28.09
    p-tert-butyltoluene 9.89
    methyl 4-tert-butylbenzoate 45.73
    morpholine 68.7
    tert-butylamine 18.94
    n-dodecanol 6.12
    dimethoxymethane 102.53
    ethylene carbonate 40.03
    cyrene 67.41
    2-ethoxyethyl acetate 36.55
    2-ethylhexyl acetate 22.6
    1,2,4-trichlorobenzene 33.91
    4-methylpyridine 29.74
    dibutyl ether 12.65
    2,6-dimethyl-4-heptanol 10.24
    DEF 61.1
    dimethyl isosorbide 99.18
    tetrachloroethylene 54.85
    eugenol 41.34
    triacetin 45.18
    span 80 29.2
    1,4-butanediol 16.92
    1,1-dichloroethane 21.02
    2-methyl-1-pentanol 13.5
    methyl formate 82.69
    2-methyl-1-butanol 11.86
    n-decane 1.25
    butyronitrile 13.1
    3,7-dimethyl-1-octanol 11.74
    1-chlorooctane 6.77
    1-chlorotetradecane 2.73
    n-nonane 1.13
    undecane 0.94
    tert-butylcyclohexane 2.1
    cyclooctane 0.89
    cyclopentanol 25.24
    tetrahydropyran 26.35
    tert-amyl methyl ether 25.55
    2,5,8-trioxanonane 81.53
    1-hexene 4.56
    2-isopropoxyethanol 39.54
    2,2,2-trifluoroethanol 46.67
    methyl butyrate 33.7

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Rhubarb root Rheum palmatum L., fam. Polygonaceae 0.01%