Ubiquinol 10

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  • Identifiers

    CAS number
    5677-55-4

    Molecular formula
    C19H28O4

    SMILES
    CC1=C(C(=C(C(=C1O)OC)OC)O)C/C=C(\C)/CCC=C(C)C

    Safety labels

  • Odor profile

    Fragrance
    Spicy 55.43%
    Woody 45.16%
    Phenolic 38.35%
    Balsamic 31.91%
    Floral 29.4%
    Fruity 29.01%
    Smoky 28.59%
    Burnt 28.54%
    Dry 26.75%
    Powdery 23.42%

     

    Flavor
    Woody 39.09%
    Spicy 32.81%
    Spice 32.47%
    Flower 29.09%
    Herbal 27.97%
    Bitter 27.88%
    Wood 25.24%
    Mild 24.97%
    Floral 23.14%
    Clove 22.67%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.3

    pKa est.
    10.2 (weak base)

    Molecular weight
    320.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    457°C

    Flash point

    • 168.07 ˚C est.

  • Synonyms

    • UBIQUINOL 10
    • 5677-55-4
    • DTXSID701317902
    • RefChem:1100623
    • DTXCID90910008
    • Coenzyme Q10, reduced
    • 2-((2E)-3,7-Dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-1,4-benzenediol
    • 2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5,6-dimethoxy-3-methylbenzene-1,4-diol
    • 2-(3,7-dimethylocta-2,6-dien-1-yl)-5,6-dimethoxy-3-methylbenzene-1,4-diol
    • ubiquinol-2
    • SCHEMBL4368813
    • CHEMBL2272030
    • CHEBI:167578
    • 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-5,6-dimethoxy-3-methylbenzene-1,4-diol
    • 2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5,6-dimethoxy-3-methyl-hydroquinone
    • 1,4-Benzenediol, 2-(3,7-dimethyl-2,6-octadienyl)-5,6-dimethoxy-3-methyl-, (E)-
    • 5677-55-4

  • Applications

    Ubiquinol 10 (CAS 5677-55-4) is used primarily as a lipid-soluble antioxidant in cosmetics and personal care, helping protect the skin and stabilize formulations; it serves as a key nutritional active in dietary supplements and nutraceuticals; it is considered for incorporation into functional foods and fortified products; and it is studied as an antioxidant stabilizer in various polymers and coating systems to enhance material oxidative stability.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 121.39
    methanol 67.02
    isopropanol 109.72
    water 0.01
    ethyl acetate 357.35
    n-propanol 153.55
    acetone 359.7
    n-butanol 136.57
    acetonitrile 105.43
    DMF 279.88
    toluene 122.23
    isobutanol 106.35
    1,4-dioxane 470.99
    methyl acetate 300.74
    THF 856.37
    2-butanone 389.12
    n-pentanol 113.51
    sec-butanol 151.22
    n-hexane 11.92
    ethylene glycol 9.15
    NMP 259.14
    cyclohexane 32.71
    DMSO 318.76
    n-butyl acetate 156.54
    n-octanol 51.27
    chloroform 477.19
    n-propyl acetate 165.95
    acetic acid 152.5
    dichloromethane 461.51
    cyclohexanone 427.59
    propylene glycol 27.31
    isopropyl acetate 170.91
    DMAc 282.04
    2-ethoxyethanol 189.99
    isopentanol 107.88
    n-heptane 9.45
    ethyl formate 128.43
    1,2-dichloroethane 347.2
    n-hexanol 107.92
    2-methoxyethanol 247.82
    isobutyl acetate 97.06
    tetrachloromethane 67.52
    n-pentyl acetate 130.56
    transcutol 328.53
    n-heptanol 70.72
    ethylbenzene 64.96
    MIBK 128.26
    2-propoxyethanol 185.22
    tert-butanol 164.06
    MTBE 210.38
    2-butoxyethanol 141.17
    propionic acid 115.66
    o-xylene 71.82
    formic acid 21.5
    diethyl ether 256.42
    m-xylene 70.11
    p-xylene 81.17
    chlorobenzene 163.05
    dimethyl carbonate 92.34
    n-octane 6.39
    formamide 57.05
    cyclopentanone 548.55
    2-pentanone 296.52
    anisole 136.99
    cyclopentyl methyl ether 263.3
    gamma-butyrolactone 470.03
    1-methoxy-2-propanol 186.26
    pyridine 366.67
    3-pentanone 224.26
    furfural 283.51
    n-dodecane 4.15
    diethylene glycol 89.11
    diisopropyl ether 57.35
    tert-amyl alcohol 165.66
    acetylacetone 278.18
    n-hexadecane 4.95
    acetophenone 139.35
    methyl propionate 253.9
    isopentyl acetate 137.4
    trichloroethylene 647.72
    n-nonanol 53.18
    cyclohexanol 164.84
    benzyl alcohol 118.57
    2-ethylhexanol 70.59
    isooctanol 60.79
    dipropyl ether 80.28
    1,2-dichlorobenzene 137.07
    ethyl lactate 65.31
    propylene carbonate 198.29
    n-methylformamide 107.69
    2-pentanol 102.41
    n-pentane 11.27
    1-propoxy-2-propanol 130.44
    1-methoxy-2-propyl acetate 160.27
    2-(2-methoxypropoxy) propanol 97.45
    mesitylene 41.78
    ε-caprolactone 335.64
    p-cymene 37.85
    epichlorohydrin 623.54
    1,1,1-trichloroethane 312.56
    2-aminoethanol 38.23
    morpholine-4-carbaldehyde 262.16
    sulfolane 412.25
    2,2,4-trimethylpentane 10.54
    2-methyltetrahydrofuran 498.56
    n-hexyl acetate 136.11
    isooctane 6.73
    2-(2-butoxyethoxy)ethanol 146.74
    sec-butyl acetate 114.33
    tert-butyl acetate 171.95
    decalin 15.15
    glycerin 38.72
    diglyme 281.48
    acrylic acid 83.57
    isopropyl myristate 46.49
    n-butyric acid 186.84
    acetyl acetate 165.07
    di(2-ethylhexyl) phthalate 49.43
    ethyl propionate 147.76
    nitromethane 293.11
    1,2-diethoxyethane 145.16
    benzonitrile 116.15
    trioctyl phosphate 38.17
    1-bromopropane 192.92
    gamma-valerolactone 492.32
    n-decanol 37.38
    triethyl phosphate 56.47
    4-methyl-2-pentanol 53.42
    propionitrile 124.07
    vinylene carbonate 155.81
    1,1,2-trichlorotrifluoroethane 274.85
    DMS 113.98
    cumene 40.84
    2-octanol 50.68
    2-hexanone 169.75
    octyl acetate 65.35
    limonene 54.48
    1,2-dimethoxyethane 293.65
    ethyl orthosilicate 58.02
    tributyl phosphate 41.52
    diacetone alcohol 177.14
    N,N-dimethylaniline 78.43
    acrylonitrile 128.66
    aniline 141.71
    1,3-propanediol 94.4
    bromobenzene 166.11
    dibromomethane 304.51
    1,1,2,2-tetrachloroethane 473.69
    2-methyl-cyclohexyl acetate 100.14
    tetrabutyl urea 53.43
    diisobutyl methanol 38.69
    2-phenylethanol 120.83
    styrene 74.56
    dioctyl adipate 71.45
    dimethyl sulfate 134.93
    ethyl butyrate 110.59
    methyl lactate 75.75
    butyl lactate 83.99
    diethyl carbonate 76.89
    propanediol butyl ether 95.72
    triethyl orthoformate 79.02
    p-tert-butyltoluene 37.92
    methyl 4-tert-butylbenzoate 109.04
    morpholine 563.75
    tert-butylamine 82.86
    n-dodecanol 26.54
    dimethoxymethane 258.1
    ethylene carbonate 141.57
    cyrene 127.61
    2-ethoxyethyl acetate 173.95
    2-ethylhexyl acetate 111.05
    1,2,4-trichlorobenzene 161.33
    4-methylpyridine 260.17
    dibutyl ether 63.12
    2,6-dimethyl-4-heptanol 38.69
    DEF 220.18
    dimethyl isosorbide 184.18
    tetrachloroethylene 260.85
    eugenol 104.85
    triacetin 116.37
    span 80 93.52
    1,4-butanediol 38.44
    1,1-dichloroethane 310.01
    2-methyl-1-pentanol 104.28
    methyl formate 99.06
    2-methyl-1-butanol 118.89
    n-decane 8.18
    butyronitrile 127.54
    3,7-dimethyl-1-octanol 51.07
    1-chlorooctane 41.15
    1-chlorotetradecane 14.55
    n-nonane 7.38
    undecane 5.57
    tert-butylcyclohexane 13.46
    cyclooctane 10.27
    cyclopentanol 174.19
    tetrahydropyran 537.32
    tert-amyl methyl ether 149.27
    2,5,8-trioxanonane 170.2
    1-hexene 47.57
    2-isopropoxyethanol 141.94
    2,2,2-trifluoroethanol 43.34
    methyl butyrate 181.04

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction