Trolamine Salicylate

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  • Identifiers

    CAS number
    2174-16-5

    Molecular formula
    C13H21NO6

    SMILES
    C1=CC=C(C(=C1)C(=O)O)O.C(CO)N(CCO)CCO

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Sweet 69.65%
    Odorless 40.91%
    Bitter 26.61%
    Balsamic 22.55%
    Vanilla 20.9%
    Fishy 20.56%
    Fruity 19.08%
    Savory 18.54%
    Almond 18.5%
    Creamy 18.12%

    Scent© AI

  • Properties

    Molecular weight
    287.31 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 50 undefined

    Boiling point

    • Decomposes

    Flash point est.
    191.13 ˚C

    Solubility expt.

    • Soluble

  • Synonyms

    • Triethanolamine salicylate
    • TROLAMINE SALICYLATE
    • 2174-16-5
    • TEA-Salicylate
    • TEA salicylate
    • Neo heliopan ts
    • Neotan w
    • Arthricream
    • Myoflex
    • Salicylic acid trolamine
    • Sunarome W
    • H8O4040BHD
    • DTXSID4047969
    • Trolamine salicylate (USP)
    • UNII-H8O4040BHD
    • Salicylic acid triethanolamine
    • DTXCID4027945
    • TRIETHANOLAMINE, SALICYLATE
    • salicylic acid triethanolamine salt
    • EINECS 218-531-3
    • Trolamine salicylate [USP]
    • TROLAMINE SALICYLATE (MART.)
    • TROLAMINE SALICYLATE [MART.]
    • TROLAMINE SALICYLATE (USP IMPURITY)
    • TROLAMINE SALICYLATE [USP IMPURITY]
    • TROLAMINE SALICYLATE (USP MONOGRAPH)
    • TROLAMINE SALICYLATE [USP MONOGRAPH]
    • Sportscreme
    • Arthritis
    • ArthritisLeader
    • Cannaflex
    • Hempvana
    • Arthritis Cream
    • Arthritis Creme
    • Asper-FlexCream
    • Arthricream (TN)
    • HempvanaPain Relief
    • Arthricreamwith Aloe
    • basic care arthritis
    • DCH Arthritis Relief
    • Copperlife Pain Relief
    • sunmark arthricream rub
    • ULTRACIN T
    • 2-[bis(2-hydroxyethyl)amino]ethanol;2-hydroxybenzoic acid
    • Arthritis with AloeCVS
    • CBD Pain Relief Cream
    • Warrior Arthritis Relief
    • Aspercreme Pain Relieving
    • KRT Athletic Muscle Gel
    • Trolamin Salicylate 10%
    • Trolamine salicylate salve
    • Trolamine Salicylate 10%
    • Meijer Analgesic with Aloe
    • Meijer Pain Relieving Balm
    • XCEPTOL PAINUNSCENTED
    • SCHEMBL15847
    • Uncle Buds Hemp Pain Relief
    • Blue-Emu Maximum Pain Relief
    • teds topical pain gel roll on
    • CannEssentia Pain Relief Cream
    • XCEPTOR CBD PAINLAVENDER
    • Alcis Daily Relief Pain Relief
    • Blue-Emu Ultra with Hemp Seed
    • Arthritis ReliefMaximum Strength
    • XCEPTOR CBD PAINUNSCENTED
    • CHEMBL2107288
    • Pain Relieving Topical Analgesic
    • Blue-Emu Pain Relief Micro-Foam
    • UEVAMYPIMMOEFW-UHFFFAOYSA-N
    • Equate Odor-Free Therapy Arthritis
    • Meijer Pain Relieving BalmAnalgesic
    • Tox21_201084
    • Hempvana Maximum Strength Pain Relief
    • TROLAMINE SALICYLATE [WHO-DD]
    • Good Neighbor Pharmacy Arthritis Cream
    • Leader Maximum Strength Pain Relieving
    • Maximum Strength Blue Emu Pain Relief
    • Walgreens Pain Relieving Plus Turmeric
    • DB11079
    • TRIETHANOLAMINE SALICYLATE [MI]
    • Dr Joe lab ARTHRITIS EXTRA STRENGTH
    • NCGC00248985-01
    • NCGC00258636-01
    • Tommie Copper Pain ReliefMaximum Strength
    • TRIETHANOLAMINE SALICYLATE [VANDF]
    • CAS-2174-16-5
    • DB-257169
    • Equate Odor-Free Therapy ArthritisAnalgesic
    • Meijer Analgesic with AloeTopical Analgesic
    • NS00083243
    • Maximum Strength Blue Emu Pain ReliefBlu Emu
    • Real Time Pain Relief Therapeutic Hand Cream
    • D08501
    • Hempvana Maximum Strength Pain Relief-Platinum
    • Leader Maximum Strength Pain RelievingAnalgesic
    • Walgreens Pain Relieving Plus TurmericAnalgesic
    • Kroger Odor Free Arthricream Rub Pain Relieving
    • Q7845153
    • Salicylic acid, compound with 2,2',2''-nitrilotriethanol (1:1)
    • 218-531-3

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 6.69
    methanol 42.84
    isopropanol 2.14
    water 398.89
    ethyl acetate 1.28
    n-propanol 4.54
    acetone 1.13
    n-butanol 2.94
    acetonitrile 1.24
    DMF 73.18
    toluene 0.3
    isobutanol 1.95
    1,4-dioxane 4.11
    methyl acetate 0.96
    THF 4.98
    2-butanone 1.03
    n-pentanol 1.94
    sec-butanol 1.83
    n-hexane 0.25
    ethylene glycol 101.22
    NMP 125.06
    cyclohexane 0.43
    DMSO 212.37
    n-butyl acetate 0.99
    n-octanol 1.3
    chloroform 1.39
    n-propyl acetate 0.74
    acetic acid 14.68
    dichloromethane 2.98
    cyclohexanone 4.26
    propylene glycol 29.75
    isopropyl acetate 0.71
    DMAc 55.32
    2-ethoxyethanol 14.98
    isopentanol 1.66
    n-heptane 0.54
    ethyl formate 2.71
    1,2-dichloroethane 3.12
    n-hexanol 2.4
    2-methoxyethanol 47.9
    isobutyl acetate 0.32
    tetrachloromethane 0.81
    n-pentyl acetate 0.84
    transcutol 11.74
    n-heptanol 2.13
    ethylbenzene 0.32
    MIBK 0.72
    2-propoxyethanol 13.21
    tert-butanol 1.97
    MTBE 0.39
    2-butoxyethanol 6.86
    propionic acid 8.77
    o-xylene 0.8
    formic acid 181.52
    diethyl ether 0.87
    m-xylene 0.59
    p-xylene 0.36
    chlorobenzene 0.36
    dimethyl carbonate 2.67
    n-octane 0.22
    formamide 126.04
    cyclopentanone 5.52
    2-pentanone 1.17
    anisole 0.53
    cyclopentyl methyl ether 2.26
    gamma-butyrolactone 14.15
    1-methoxy-2-propanol 18.92
    pyridine 1.73
    3-pentanone 1.45
    furfural 15.13
    n-dodecane 0.11
    diethylene glycol 40.72
    diisopropyl ether 0.34
    tert-amyl alcohol 1.69
    acetylacetone 1.83
    n-hexadecane 0.12
    acetophenone 1.51
    methyl propionate 2.92
    isopentyl acetate 0.69
    trichloroethylene 2.78
    n-nonanol 1.29
    cyclohexanol 3.2
    benzyl alcohol 2.09
    2-ethylhexanol 1.27
    isooctanol 1.42
    dipropyl ether 1.37
    1,2-dichlorobenzene 0.81
    ethyl lactate 3.98
    propylene carbonate 5.15
    n-methylformamide 39.45
    2-pentanol 1.35
    n-pentane 0.33
    1-propoxy-2-propanol 6.42
    1-methoxy-2-propyl acetate 2.74
    2-(2-methoxypropoxy) propanol 5.38
    mesitylene 0.6
    ε-caprolactone 6.11
    p-cymene 0.65
    epichlorohydrin 6.56
    1,1,1-trichloroethane 0.65
    2-aminoethanol 57.2
    morpholine-4-carbaldehyde 53.59
    sulfolane 68.3
    2,2,4-trimethylpentane 0.13
    2-methyltetrahydrofuran 1.91
    n-hexyl acetate 0.98
    isooctane 0.08
    2-(2-butoxyethoxy)ethanol 7.57
    sec-butyl acetate 0.4
    tert-butyl acetate 0.77
    decalin 0.2
    glycerin 113.07
    diglyme 11.87
    acrylic acid 15.35
    isopropyl myristate 0.42
    n-butyric acid 5.63
    acetyl acetate 0.97
    di(2-ethylhexyl) phthalate 1.43
    ethyl propionate 1.17
    nitromethane 13.9
    1,2-diethoxyethane 1.35
    benzonitrile 1.09
    trioctyl phosphate 1.26
    1-bromopropane 1.0
    gamma-valerolactone 17.38
    n-decanol 0.96
    triethyl phosphate 1.7
    4-methyl-2-pentanol 0.81
    propionitrile 1.27
    vinylene carbonate 5.37
    1,1,2-trichlorotrifluoroethane 30.46
    DMS 1.66
    cumene 0.36
    2-octanol 0.93
    2-hexanone 0.68
    octyl acetate 0.69
    limonene 0.9
    1,2-dimethoxyethane 7.42
    ethyl orthosilicate 1.47
    tributyl phosphate 1.13
    diacetone alcohol 3.62
    N,N-dimethylaniline 1.32
    acrylonitrile 2.73
    aniline 1.16
    1,3-propanediol 27.7
    bromobenzene 0.28
    dibromomethane 1.75
    1,1,2,2-tetrachloroethane 3.96
    2-methyl-cyclohexyl acetate 1.16
    tetrabutyl urea 2.28
    diisobutyl methanol 0.8
    2-phenylethanol 2.09
    styrene 0.23
    dioctyl adipate 1.01
    dimethyl sulfate 12.16
    ethyl butyrate 1.12
    methyl lactate 13.0
    butyl lactate 2.88
    diethyl carbonate 0.88
    propanediol butyl ether 7.14
    triethyl orthoformate 1.35
    p-tert-butyltoluene 0.61
    methyl 4-tert-butylbenzoate 3.33
    morpholine 7.79
    tert-butylamine 0.91
    n-dodecanol 0.73
    dimethoxymethane 11.21
    ethylene carbonate 3.99
    cyrene 17.87
    2-ethoxyethyl acetate 1.44
    2-ethylhexyl acetate 0.64
    1,2,4-trichlorobenzene 1.0
    4-methylpyridine 1.29
    dibutyl ether 0.54
    2,6-dimethyl-4-heptanol 0.8
    DEF 8.36
    dimethyl isosorbide 9.41
    tetrachloroethylene 3.91
    eugenol 4.51
    triacetin 2.09
    span 80 5.95
    1,4-butanediol 13.81
    1,1-dichloroethane 0.69
    2-methyl-1-pentanol 1.24
    methyl formate 14.8
    2-methyl-1-butanol 1.91
    n-decane 0.18
    butyronitrile 1.1
    3,7-dimethyl-1-octanol 0.86
    1-chlorooctane 0.45
    1-chlorotetradecane 0.21
    n-nonane 0.18
    undecane 0.14
    tert-butylcyclohexane 0.12
    cyclooctane 0.32
    cyclopentanol 4.27
    tetrahydropyran 1.46
    tert-amyl methyl ether 0.74
    2,5,8-trioxanonane 10.05
    1-hexene 0.37
    2-isopropoxyethanol 4.8
    2,2,2-trifluoroethanol 21.01
    methyl butyrate 1.42

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction