Tripalmitin

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  • Identifiers

    CAS number
    555-44-2

    Molecular formula
    C51H98O6

    SMILES
    CCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC

    Safety labels

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Waxy 73.01%
    Fatty 64.93%
    Oily 49.02%
    Odorless 37.93%
    Creamy 24.83%
    Sweet 21.02%
    Buttery 18.4%
    Dairy 17.82%
    Milky 17.01%
    Alcoholic 16.54%

     

    Flavor
    Waxy 56.47%
    Fatty 48.36%
    Mild 45.06%
    Oily 43.98%
    Bland 38.32%
    Faint 33.1%
    Fat 28.68%
    Odorless 27.64%
    Soapy 27.09%
    Creamy 26.12%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    21.9

    pKa est.
    10.39 (weak base)

    Molecular weight
    807.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    618°C

    Flash point

    • 287.28 ˚C est.

  • Synonyms

    • TRIPALMITIN
    • 555-44-2
    • Glycerol tripalmitate
    • Glyceryl tripalmitate
    • Tripalmitoylglycerol
    • Palmitic triglyceride
    • Tripalmitate
    • Dynasan 116
    • Triglyceryl palmitate
    • Barolub
    • Spezialfett 116
    • Glyceryl trihexadecanoate
    • Barolub LCD
    • Hexadecanoic acid, 1,2,3-propanetriyl ester
    • Speziafett 116
    • Palmitic acid triglycerin ester
    • Dynosan 114
    • tripalmitina
    • tripalmitine
    • 1,2,3-trihexadecanoyl-sn-glycerol
    • 2,3-di(hexadecanoyloxy)propyl hexadecanoate
    • 1,2,3-Propanetriol trihexadecanoate
    • Hexadecanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester
    • D133ZRF50U
    • DTXSID8046169
    • TG(16:0/16:0/16:0)
    • 1,2,3-propanetriyl trihexadecanoate
    • DTXCID6026169
    • CHEBI:77393
    • Tripalmitoyl glycerol
    • tripalmitinum
    • tripalmitylglycerol
    • glycero-tripalmitate
    • RefChem:6330
    • GlyTouCan:G00932FV
    • G00932FV
    • 209-098-1
    • Palmitic acid triglyceride
    • Propane-1,2,3-triyl tripalmitate
    • Tripalmitin [INN]
    • Glycerin tripalmitate
    • Palmitin, tri-
    • MFCD00008995
    • 1,2,3-trihexadecanoyl-glycerol
    • propane-1,2,3-triyl trihexadecanoate
    • 1,3-bis(hexadecanoyloxy)propan-2-yl hexadecanoate
    • 1,2,3-trihexadecanoylglycerol
    • C51H98O6
    • NCGC00160468-01
    • CCRIS 6992
    • EINECS 209-098-1
    • BRN 1811188
    • UNII-D133ZRF50U
    • AI3-31759
    • Triglyceride PPP
    • Glyceryltripalmitate
    • glycerol tripalmtate
    • trihexadecanoylglycerol
    • TRIPALMITIN [MI]
    • Glyceryl trihexadecanoic acid
    • SCHEMBL24941
    • 4-02-00-01176 (Beilstein Handbook Reference)
    • Tripalmitin or 1,2,3-propanetriyl trihexadecanoate
    • Glycerol tripalmitate,97.5%
    • Tripalmitin-1,1,1-13C3
    • Glyceryl tripalmitate, >=85%
    • Glyceryl tripalmitate, >=99%
    • orb1296051
    • CHEMBL2002154
    • MSK2025
    • HY-W013061R
    • Tox21_111834
    • LMGL03010001
    • AKOS015899780
    • CS-W013777
    • EBC-616165
    • FG11067
    • HY-W013061
    • 2,3-Bis(palmitoyloxy)propyl palmitate #
    • NCGC00160468-02
    • Tripalmitin, NIST(R) SRM(R) 1595
    • AS-60925
    • CAS-555-44-2
    • FG179174
    • SY048302
    • G0091
    • G0213
    • NS00014187
    • T3096
    • Propane-1,2,3-triyl tripalmitate (Standard)
    • D90728
    • T-6810
    • SR-01000944841
    • Q7843226
    • SR-01000944841-1
    • TG 16:0/16:0/16:0
    • 555-44-2

  • Applications

    Tripalmitin (glyceryl tripalmitate; CAS 555-44-2) is a solid lipid widely used as a lipid-based excipient and carrier in cosmetics and personal care formulations, where it acts as an emollient, thickener, and carrier for fragrances or active ingredients. In the pharmaceutical and nutraceutical sectors it serves as a lipid base for drug-delivery systems and as a component in lipid nanoparticles. In oleochemical and industrial manufacturing, it is used as a feedstock for synthesis of modified fats and specialty lubricants. In perfumery and flavor applications it can function as a carrier oil for volatile fragrance and flavor components.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.17
    methanol 12.89
    isopropanol 10.71
    water 0.47
    ethyl acetate 159.38
    n-propanol 18.56
    acetone 103.82
    n-butanol 17.14
    acetonitrile 41.35
    DMF 211.27
    toluene 64.86
    isobutanol 17.25
    1,4-dioxane 114.82
    methyl acetate 132.33
    THF 276.99
    2-butanone 138.25
    n-pentanol 20.01
    sec-butanol 24.36
    n-hexane 10.28
    ethylene glycol 2.71
    NMP 793.37
    cyclohexane 27.65
    DMSO 217.2
    n-butyl acetate 112.72
    n-octanol 28.72
    chloroform 444.79
    n-propyl acetate 142.88
    acetic acid 96.18
    dichloromethane 476.11
    cyclohexanone 349.64
    propylene glycol 6.7
    isopropyl acetate 134.62
    DMAc 595.94
    2-ethoxyethanol 56.86
    isopentanol 19.76
    n-heptane 8.11
    ethyl formate 78.93
    1,2-dichloroethane 246.52
    n-hexanol 15.74
    2-methoxyethanol 52.08
    isobutyl acetate 81.33
    tetrachloromethane 107.83
    n-pentyl acetate 203.45
    transcutol 279.5
    n-heptanol 23.71
    ethylbenzene 44.34
    MIBK 88.62
    2-propoxyethanol 53.48
    tert-butanol 20.33
    MTBE 61.75
    2-butoxyethanol 80.42
    propionic acid 76.26
    o-xylene 71.76
    formic acid 26.39
    diethyl ether 49.03
    m-xylene 49.45
    p-xylene 68.05
    chlorobenzene 139.15
    dimethyl carbonate 109.19
    n-octane 5.62
    formamide 49.0
    cyclopentanone 420.21
    2-pentanone 116.51
    anisole 88.52
    cyclopentyl methyl ether 162.7
    gamma-butyrolactone 553.64
    1-methoxy-2-propanol 56.23
    pyridine 181.08
    3-pentanone 149.04
    furfural 376.88
    n-dodecane 3.23
    diethylene glycol 22.02
    diisopropyl ether 29.13
    tert-amyl alcohol 41.66
    acetylacetone 244.88
    n-hexadecane 3.86
    acetophenone 164.49
    methyl propionate 160.99
    isopentyl acetate 109.08
    trichloroethylene 578.71
    n-nonanol 31.21
    cyclohexanol 52.94
    benzyl alcohol 48.35
    2-ethylhexanol 22.1
    isooctanol 26.04
    dipropyl ether 53.79
    1,2-dichlorobenzene 212.26
    ethyl lactate 75.54
    propylene carbonate 333.34
    n-methylformamide 83.02
    2-pentanol 19.25
    n-pentane 6.47
    1-propoxy-2-propanol 63.88
    1-methoxy-2-propyl acetate 146.98
    2-(2-methoxypropoxy) propanol 99.92
    mesitylene 36.78
    ε-caprolactone 404.21
    p-cymene 34.2
    epichlorohydrin 409.96
    1,1,1-trichloroethane 374.09
    2-aminoethanol 8.67
    morpholine-4-carbaldehyde 346.76
    sulfolane 953.95
    2,2,4-trimethylpentane 9.97
    2-methyltetrahydrofuran 215.32
    n-hexyl acetate 173.09
    isooctane 3.67
    2-(2-butoxyethoxy)ethanol 101.82
    sec-butyl acetate 119.16
    tert-butyl acetate 177.81
    decalin 17.29
    glycerin 15.27
    diglyme 278.87
    acrylic acid 71.37
    isopropyl myristate 52.91
    n-butyric acid 119.01
    acetyl acetate 182.09
    di(2-ethylhexyl) phthalate 59.71
    ethyl propionate 157.01
    nitromethane 282.46
    1,2-diethoxyethane 126.65
    benzonitrile 78.23
    trioctyl phosphate 38.49
    1-bromopropane 107.24
    gamma-valerolactone 529.56
    n-decanol 18.81
    triethyl phosphate 109.99
    4-methyl-2-pentanol 14.98
    propionitrile 45.03
    vinylene carbonate 282.05
    1,1,2-trichlorotrifluoroethane 330.14
    DMS 174.49
    cumene 33.21
    2-octanol 24.54
    2-hexanone 113.46
    octyl acetate 72.02
    limonene 56.2
    1,2-dimethoxyethane 139.97
    ethyl orthosilicate 94.97
    tributyl phosphate 59.33
    diacetone alcohol 123.74
    N,N-dimethylaniline 80.02
    acrylonitrile 61.02
    aniline 61.07
    1,3-propanediol 14.94
    bromobenzene 175.66
    dibromomethane 249.93
    1,1,2,2-tetrachloroethane 537.73
    2-methyl-cyclohexyl acetate 120.43
    tetrabutyl urea 89.82
    diisobutyl methanol 17.16
    2-phenylethanol 38.93
    styrene 51.24
    dioctyl adipate 108.44
    dimethyl sulfate 326.38
    ethyl butyrate 139.28
    methyl lactate 84.95
    butyl lactate 133.38
    diethyl carbonate 98.0
    propanediol butyl ether 61.49
    triethyl orthoformate 125.75
    p-tert-butyltoluene 31.95
    methyl 4-tert-butylbenzoate 204.66
    morpholine 137.11
    tert-butylamine 14.51
    n-dodecanol 12.45
    dimethoxymethane 110.22
    ethylene carbonate 232.17
    cyrene 143.63
    2-ethoxyethyl acetate 262.9
    2-ethylhexyl acetate 101.43
    1,2,4-trichlorobenzene 292.16
    4-methylpyridine 172.0
    dibutyl ether 66.71
    2,6-dimethyl-4-heptanol 17.16
    DEF 212.58
    dimethyl isosorbide 244.58
    tetrachloroethylene 318.55
    eugenol 125.43
    triacetin 305.46
    span 80 81.94
    1,4-butanediol 9.64
    1,1-dichloroethane 210.12
    2-methyl-1-pentanol 26.79
    methyl formate 80.24
    2-methyl-1-butanol 25.61
    n-decane 7.74
    butyronitrile 39.31
    3,7-dimethyl-1-octanol 30.07
    1-chlorooctane 40.75
    1-chlorotetradecane 12.2
    n-nonane 7.2
    undecane 4.6
    tert-butylcyclohexane 11.99
    cyclooctane 11.77
    cyclopentanol 60.85
    tetrahydropyran 139.27
    tert-amyl methyl ether 86.44
    2,5,8-trioxanonane 158.49
    1-hexene 25.08
    2-isopropoxyethanol 49.62
    2,2,2-trifluoroethanol 85.34
    methyl butyrate 199.89

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction