Triethylamine

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  • Identifiers

    CAS number
    121-44-8

    Molecular formula
    C6H15N

    SMILES
    CCN(CC)CC

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fishy 86.02%
    Cheesy 78.05%
    Ripe 63.9%
    Animal 28.43%
    Oily 20.19%
    Musty 20.16%
    Meaty 19.06%
    Pungent 18.91%
    Odorless 18.58%
    Savory 16.28%

    Scent© AI

    Odor threshold>

    • Odor Threshold Low: 0.1 [mmHg]. Odor Threshold High: 0.65 [mmHg]. Detection odor threshold from AIHA (mean = 0.25 ppm)
    • Odor detection in air= 9.00X10-2 ppm (purity not specified)
    • Odor recognition in air= 2.80X10-1 ppm (purity not specified)
    • Odor low: 0.36 mg/cu m; Odor high: 1.12 mg/cu m

  • Properties

    XLogP3-AA
    1.4

    Molecular weight
    101.19 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -174.5 °F (NTP, 1992)
    • -114.7 °C
    • -115 °C
    • -175 °F

    Boiling point

    • 192.7 °F at 760 mmHg (NTP, 1992)
    • 88.8 °C
    • 88.80 to 89.00 °C. @ 760.00 mm Hg
    • 89 °C
    • 193 °F

    Flash point est.
    -13.05 ˚C

    Flash point expt.

    • 20 °F (NTP, 1992)
    • -7 °C
    • -15 °C (5 °F) - closed cup
    • 16 °F (-7 °F) (open cup)
    • -17 °C c.c.
    • 20 °F

    Solubility expt.

    • Soluble (NTP, 1992)
    • In water, 6.86X10+4 mg/L at 25 °C
    • Miscible with water below 18.7 °C
    • Soluble in ethanol, carbon tetrachloride, ethyl ether; very soluble in acetone, benzene, chloroform
    • Soluble in fixed oils, mineral oil, oleic and stearic acids and in hot carnauba and paraffin waxes.
    • For more Solubility (Complete) data for TRIETHYLAMINE (6 total), please visit the HSDB record page.
    • 68.6 mg/mL at 25 °C
    • Solubility in water, g/100ml at 20 °C: 17 (good)
    • Soluble in water
    • Soluble (in ethanol)
    • 2%

  • Synonyms

    • TRIETHYLAMINE
    • 121-44-8
    • N,N-Diethylethanamine
    • (Diethylamino)ethane
    • Ethanamine, N,N-diethyl-
    • triethyl amine
    • Triaethylamin
    • Triethylamin
    • Trietilamina
    • N,N,N-Triethylamine
    • Diethylaminoethane
    • NEt3
    • Triaethylamin [German]
    • Trietilamina [Italian]
    • (C2H5)3N
    • MFCD00009051
    • TEN [Base]
    • trietylamine
    • CCRIS 4881
    • HSDB 896
    • tri-ethyl amine
    • UNII-VOU728O6AY
    • EINECS 204-469-4
    • VOU728O6AY
    • DTXSID3024366
    • CHEBI:35026
    • AI3-15425
    • N,N-diethyl-ethanamine
    • TRIETHYLAMINE [MI]
    • TRIETHYLAMINE [FHFI]
    • TRIETHYLAMINE [HSDB]
    • TRIETHYLAMINE [USP-RS]
    • DTXCID204366
    • FEMA NO. 4246
    • EC 204-469-4
    • ethane, diethylamino-
    • TEN (Base)
    • Triaethylamin (German)
    • Trietilamina (Italian)
    • Triethylamine, >=99.5%
    • TRIETHYLAMINE (USP-RS)
    • triethyl-amine
    • Et3N
    • UN1296
    • triehtylamine
    • triehylamine
    • trieihylamine
    • triethlyamine
    • triethyamine
    • triethylamme
    • triethylarnine
    • Thethylamine
    • Triethlamine
    • triethyIamine
    • Triethylannine
    • tri-ethylamine
    • triehyl amine
    • triethyl amin
    • triethylam ine
    • triethylami-ne
    • triethylamine-
    • trietyl amine
    • tri ethyl amine
    • triethyl- amine
    • N,NDiethylethanamine
    • n,n-diethylaminoethane
    • Ethanamine, N,Ndiethyl
    • N, N-diethylethanamine
    • Trietilamina UN1296
    • N,N,N-Triethylamine #
    • triethylamine, 99.5%
    • Triethylamine, >=99%
    • Triethylamine [UN1296] [Flammable liquid]
    • N(Et)3
    • NCIOpen2_006503
    • TRIETHYLAMINE [INCI]
    • Triethylamine (ACGIH:OSHA)
    • BIDD:ER0331
    • Triethylamine, LR, >=99%
    • (CH3CH2)3N
    • CHEMBL284057
    • N(CH2CH3)3
    • Triethylamine, HPLC, 99.6%
    • Triethylamine, p.a., 99.0%
    • Triethylamine, analytical standard
    • BCP07310
    • N(C2H5)3
    • RCA68879
    • Triethylamine, for synthesis, 99%
    • Tox21_200873
    • Triethylamine, 99.7%, extra pure
    • STL282722
    • AKOS000119998
    • Triethylamine, purum, >=99% (GC)
    • Triethylamine, ZerO2(TM), >=99%
    • UN 1296
    • NCGC00248857-01
    • NCGC00258427-01
    • CAS-121-44-8
    • Triethylamine, BioUltra, >=99.5% (GC)
    • Triethylamine, SAJ first grade, >=98.0%
    • NS00002646
    • T0424
    • Triethylamine 100 microg/mL in Acetonitrile
    • EN300-35419
    • Triethylamine [UN1296] [Flammable liquid]
    • Triethylamine, trace metals grade, 99.99%
    • Triethylamine, SAJ special grade, >=98.0%
    • Triethylamine (contains < 0.01% Diethylamine)
    • Triethylamine, puriss. p.a., >=99.5% (GC)
    • Q139199
    • F0001-0344
    • Triethylamine, for amino acid analysis, >=99.5% (GC)
    • Triethylamine, for protein sequence analysis, ampule, >=99.5% (GC)
    • Triethylamine, United States Pharmacopeia (USP) Reference Standard
    • 204-469-4

  • Applications

    Triethylamine (TEA, CAS 121-44-8) is a versatile organic base used industrially and in laboratories as an acid scavenger and catalyst for alkylation, acylation, esterification, polyurethane and epoxy polymerizations, a neutralizing agent in paints, inks and water treatment, a gas-scrubbing reagent for HCl and CO₂, a selective solvent for resins, dyes and pesticides, an extractant in pharmaceutical processing, a blowing agent precursor for foundry sand binders, an intermediate for quaternary ammonium salts, surfactants, rubber accelerators, fuel and lubricant additives, photographic chemicals, a mobile-phase modifier in high-performance liquid chromatography, and generally as a pH regulator and corrosion inhibitor across many industrial operations.

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 136.41
    methanol 170.32
    isopropanol 89.27
    water 0.91
    ethyl acetate 144.7
    n-propanol 142.9
    acetone 103.61
    n-butanol 150.41
    acetonitrile 110.66
    DMF 88.15
    toluene 112.04
    isobutanol 99.32
    1,4-dioxane 291.89
    methyl acetate 126.37
    THF 441.44
    2-butanone 139.2
    n-pentanol 91.73
    sec-butanol 125.98
    n-hexane 142.51
    ethylene glycol 34.59
    NMP 297.06
    cyclohexane 295.12
    DMSO 136.27
    n-butyl acetate 258.86
    n-octanol 82.55
    chloroform 772.84
    n-propyl acetate 97.55
    acetic acid 204.36
    dichloromethane 619.67
    cyclohexanone 317.32
    propylene glycol 45.76
    isopropyl acetate 77.57
    DMAc 115.25
    2-ethoxyethanol 100.05
    isopentanol 104.22
    n-heptane 205.25
    ethyl formate 106.44
    1,2-dichloroethane 304.74
    n-hexanol 195.95
    2-methoxyethanol 150.16
    isobutyl acetate 66.43
    tetrachloromethane 310.03
    n-pentyl acetate 132.12
    transcutol 299.8
    n-heptanol 87.25
    ethylbenzene 64.22
    MIBK 51.56
    2-propoxyethanol 195.61
    tert-butanol 109.15
    MTBE 132.38
    2-butoxyethanol 116.03
    propionic acid 160.88
    o-xylene 85.19
    formic acid 62.18
    diethyl ether 191.78
    m-xylene 61.83
    p-xylene 81.58
    chlorobenzene 196.51
    dimethyl carbonate 25.48
    n-octane 56.07
    formamide 60.2
    cyclopentanone 301.57
    2-pentanone 98.48
    anisole 88.23
    cyclopentyl methyl ether 229.03
    gamma-butyrolactone 348.28
    1-methoxy-2-propanol 86.61
    pyridine 272.01
    3-pentanone 114.12
    furfural 297.2
    n-dodecane 31.42
    diethylene glycol 115.19
    diisopropyl ether 57.44
    tert-amyl alcohol 141.33
    acetylacetone 83.6
    n-hexadecane 34.64
    acetophenone 82.73
    methyl propionate 90.69
    isopentyl acetate 197.32
    trichloroethylene 493.74
    n-nonanol 78.27
    cyclohexanol 215.93
    benzyl alcohol 77.58
    2-ethylhexanol 172.53
    isooctanol 69.64
    dipropyl ether 238.98
    1,2-dichlorobenzene 194.25
    ethyl lactate 48.86
    propylene carbonate 192.21
    n-methylformamide 78.92
    2-pentanol 94.92
    n-pentane 120.85
    1-propoxy-2-propanol 176.61
    1-methoxy-2-propyl acetate 140.21
    2-(2-methoxypropoxy) propanol 110.53
    mesitylene 43.98
    ε-caprolactone 291.84
    p-cymene 103.11
    epichlorohydrin 289.19
    1,1,1-trichloroethane 367.22
    2-aminoethanol 72.36
    morpholine-4-carbaldehyde 201.88
    sulfolane 385.47
    2,2,4-trimethylpentane 55.47
    2-methyltetrahydrofuran 402.1
    n-hexyl acetate 153.56
    isooctane 25.23
    2-(2-butoxyethoxy)ethanol 132.57
    sec-butyl acetate 71.01
    tert-butyl acetate 80.79
    decalin 80.83
    glycerin 61.56
    diglyme 227.62
    acrylic acid 135.67
    isopropyl myristate 79.27
    n-butyric acid 199.71
    acetyl acetate 103.13
    di(2-ethylhexyl) phthalate 74.58
    ethyl propionate 87.27
    nitromethane 159.64
    1,2-diethoxyethane 205.2
    benzonitrile 127.97
    trioctyl phosphate 55.35
    1-bromopropane 296.91
    gamma-valerolactone 294.86
    n-decanol 60.59
    triethyl phosphate 103.63
    4-methyl-2-pentanol 48.42
    propionitrile 135.51
    vinylene carbonate 166.0
    1,1,2-trichlorotrifluoroethane 254.55
    DMS 92.42
    cumene 53.33
    2-octanol 66.03
    2-hexanone 94.57
    octyl acetate 92.23
    limonene 186.29
    1,2-dimethoxyethane 165.3
    ethyl orthosilicate 108.42
    tributyl phosphate 78.43
    diacetone alcohol 71.91
    N,N-dimethylaniline 61.04
    acrylonitrile 132.66
    aniline 136.9
    1,3-propanediol 89.26
    bromobenzene 209.06
    dibromomethane 489.27
    1,1,2,2-tetrachloroethane 445.87
    2-methyl-cyclohexyl acetate 163.96
    tetrabutyl urea 86.4
    diisobutyl methanol 84.78
    2-phenylethanol 121.83
    styrene 78.17
    dioctyl adipate 109.7
    dimethyl sulfate 48.32
    ethyl butyrate 187.8
    methyl lactate 44.61
    butyl lactate 94.7
    diethyl carbonate 115.95
    propanediol butyl ether 76.13
    triethyl orthoformate 162.94
    p-tert-butyltoluene 99.24
    methyl 4-tert-butylbenzoate 103.84
    morpholine 298.08
    tert-butylamine 105.61
    n-dodecanol 50.57
    dimethoxymethane 68.9
    ethylene carbonate 139.64
    cyrene 95.35
    2-ethoxyethyl acetate 138.06
    2-ethylhexyl acetate 207.49
    1,2,4-trichlorobenzene 231.17
    4-methylpyridine 188.47
    dibutyl ether 163.19
    2,6-dimethyl-4-heptanol 84.78
    DEF 122.76
    dimethyl isosorbide 225.12
    tetrachloroethylene 406.95
    eugenol 93.01
    triacetin 122.51
    span 80 129.15
    1,4-butanediol 39.55
    1,1-dichloroethane 284.3
    2-methyl-1-pentanol 86.61
    methyl formate 62.16
    2-methyl-1-butanol 123.28
    n-decane 53.03
    butyronitrile 133.81
    3,7-dimethyl-1-octanol 95.19
    1-chlorooctane 110.39
    1-chlorotetradecane 52.59
    n-nonane 59.08
    undecane 38.37
    tert-butylcyclohexane 67.6
    cyclooctane 96.37
    cyclopentanol 223.29
    tetrahydropyran 385.6
    tert-amyl methyl ether 132.13
    2,5,8-trioxanonane 172.62
    1-hexene 171.21
    2-isopropoxyethanol 76.77
    2,2,2-trifluoroethanol 73.16
    methyl butyrate 107.83

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction