Triethyl phosphite

Overview IFRA Request a quote

  • Identifiers

    CAS number
    122-52-1

    Molecular formula
    C6H15O3P

    SMILES
    CCOP(OCC)OCC

    Safety labels

    Flammable
    Flammable

    Irritant
    Irritant

  • Odor profile

    Fruity 54.2%
    Ethereal 44.42%
    Alcoholic 38.91%
    Sweet 34.01%
    Odorless 30.22%
    Fresh 25.49%
    Solvent 21.85%
    Pungent 19.83%
    Fermented 19.52%
    Sharp 16.56%

    Scent© AI

  • Properties

    XLogP3-AA
    1.2

    Molecular weight
    166.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -112 °C

    Boiling point

    • 311 °F at 760 mmHg (USCG, 1999)
    • 157.9 °C
    • 157-159 °C

    Flash point est.
    49.54 ˚C

    Flash point expt.

    • 115 °F (USCG, 1999)
    • 54 °C (129 °F) - closed cup
    • 54 °C c.c.

    Solubility expt.

    • Soluble in alcohol, ether
    • Solubility in water: reaction

  • Synonyms

    • TRIETHYL PHOSPHITE
    • 122-52-1
    • Triethoxyphosphine
    • Phosphorous acid, triethyl ester
    • triethylphosphite
    • Ethyl phosphite, (EtO)3P
    • Phosphorous Acid Triethyl Ester
    • Fosforyn trojetylowy
    • Fosforyn trojetylowy [Czech]
    • Triethoxyphosphine-d15
    • HSDB 895
    • Phosphorus ether
    • NSC 5284
    • EINECS 204-552-5
    • UN2323
    • UNII-6B2R04S55G
    • BRN 0956578
    • DTXSID2026991
    • (C2H5O)3P
    • AI3-15624
    • 6B2R04S55G
    • NSC-5284
    • P(OEt)3
    • TRIS(ETHOXY)PHOSPHINE
    • DTXCID506991
    • TRIETHYL PHOSPHITE [MI]
    • TRIETHYL PHOSPHITE [HSDB]
    • EC 204-552-5
    • 4-01-00-01333 (Beilstein Handbook Reference)
    • UN 2323
    • Fosforyn trojetylowy (Czech)
    • 147672-00-2
    • CAS-122-52-1
    • triethyl-phosphite
    • tri ethyl phosphite
    • Ethyl phosphite, (EtO)3P (7CI); Ethyl phosphite, Et3PO3 (4CI); NSC 5284; Triethoxyphosphine; Tris(ethoxy)phosphine
    • Triethyl phosphite, 98%
    • (EtO)3P
    • SCHEMBL6102
    • SCHEMBL6509618
    • CHEMBL3186349
    • P(OC2H5)3
    • NSC5284
    • XFA67200
    • Tox21_201603
    • Tox21_303083
    • MFCD00009084
    • AKOS000119964
    • NCGC00164018-01
    • NCGC00164018-02
    • NCGC00257080-01
    • NCGC00259152-01
    • BP-31214
    • NS00004886
    • T0430
    • Triethyl phosphite, purum, >=95.0% (GC)
    • A804911
    • A937097
    • Q414714
    • Triethyl phosphite [UN2323] [Flammable liquid]
    • Triethyl phosphite 100 microg/mL in Acetonitrile
    • 204-552-5

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 579.68
    methanol 672.26
    isopropanol 645.29
    water 3.21
    ethyl acetate 724.74
    n-propanol 632.98
    acetone 1104.84
    n-butanol 530.54
    acetonitrile 801.67
    DMF 1930.04
    toluene 690.32
    isobutanol 502.69
    1,4-dioxane 1508.01
    methyl acetate 872.62
    THF 1950.66
    2-butanone 969.68
    n-pentanol 434.99
    sec-butanol 695.97
    n-hexane 282.23
    ethylene glycol 172.02
    NMP 2216.47
    cyclohexane 767.25
    DMSO 1606.56
    n-butyl acetate 724.46
    n-octanol 508.42
    chloroform 5038.73
    n-propyl acetate 606.35
    acetic acid 1007.2
    dichloromethane 4247.8
    cyclohexanone 1923.45
    propylene glycol 269.6
    isopropyl acetate 466.02
    DMAc 1454.36
    2-ethoxyethanol 474.23
    isopentanol 387.85
    n-heptane 288.96
    ethyl formate 659.77
    1,2-dichloroethane 2122.08
    n-hexanol 499.01
    2-methoxyethanol 760.24
    isobutyl acetate 394.68
    tetrachloromethane 969.4
    n-pentyl acetate 702.82
    transcutol 775.8
    n-heptanol 389.91
    ethylbenzene 447.49
    MIBK 402.2
    2-propoxyethanol 581.85
    tert-butanol 695.55
    MTBE 625.01
    2-butoxyethanol 457.96
    propionic acid 877.12
    o-xylene 497.58
    formic acid 247.85
    diethyl ether 666.19
    m-xylene 396.6
    p-xylene 651.23
    chlorobenzene 1351.11
    dimethyl carbonate 367.55
    n-octane 168.46
    formamide 396.05
    cyclopentanone 2081.15
    2-pentanone 707.0
    anisole 624.8
    cyclopentyl methyl ether 951.33
    gamma-butyrolactone 2402.19
    1-methoxy-2-propanol 628.56
    pyridine 1964.82
    3-pentanone 678.66
    furfural 2040.41
    n-dodecane 134.94
    diethylene glycol 361.02
    diisopropyl ether 255.32
    tert-amyl alcohol 676.92
    acetylacetone 765.97
    n-hexadecane 153.14
    acetophenone 716.91
    methyl propionate 697.91
    isopentyl acetate 581.08
    trichloroethylene 3985.61
    n-nonanol 436.25
    cyclohexanol 929.71
    benzyl alcohol 573.26
    2-ethylhexanol 408.06
    isooctanol 325.52
    dipropyl ether 536.2
    1,2-dichlorobenzene 1271.81
    ethyl lactate 330.99
    propylene carbonate 1263.02
    n-methylformamide 897.11
    2-pentanol 442.04
    n-pentane 262.13
    1-propoxy-2-propanol 518.05
    1-methoxy-2-propyl acetate 516.48
    2-(2-methoxypropoxy) propanol 393.05
    mesitylene 293.86
    ε-caprolactone 1575.95
    p-cymene 337.2
    epichlorohydrin 1997.56
    1,1,1-trichloroethane 2157.04
    2-aminoethanol 316.7
    morpholine-4-carbaldehyde 1500.89
    sulfolane 2973.4
    2,2,4-trimethylpentane 146.47
    2-methyltetrahydrofuran 1520.89
    n-hexyl acetate 896.42
    isooctane 80.51
    2-(2-butoxyethoxy)ethanol 495.46
    sec-butyl acetate 393.04
    tert-butyl acetate 485.77
    decalin 264.63
    glycerin 325.64
    diglyme 946.57
    acrylic acid 871.86
    isopropyl myristate 382.95
    n-butyric acid 901.13
    acetyl acetate 546.41
    di(2-ethylhexyl) phthalate 339.81
    ethyl propionate 526.81
    nitromethane 1504.02
    1,2-diethoxyethane 592.36
    benzonitrile 1063.97
    trioctyl phosphate 293.68
    1-bromopropane 1337.41
    gamma-valerolactone 2112.69
    n-decanol 322.99
    triethyl phosphate 369.08
    4-methyl-2-pentanol 230.83
    propionitrile 880.63
    vinylene carbonate 1425.69
    1,1,2-trichlorotrifluoroethane 1610.47
    DMS 611.59
    cumene 289.91
    2-octanol 408.42
    2-hexanone 593.23
    octyl acetate 492.33
    limonene 519.3
    1,2-dimethoxyethane 1025.59
    ethyl orthosilicate 340.55
    tributyl phosphate 341.76
    diacetone alcohol 445.65
    N,N-dimethylaniline 495.01
    acrylonitrile 1150.58
    aniline 730.06
    1,3-propanediol 412.66
    bromobenzene 1535.2
    dibromomethane 2993.06
    1,1,2,2-tetrachloroethane 3475.08
    2-methyl-cyclohexyl acetate 539.11
    tetrabutyl urea 477.14
    diisobutyl methanol 265.55
    2-phenylethanol 518.25
    styrene 616.13
    dioctyl adipate 514.11
    dimethyl sulfate 659.55
    ethyl butyrate 577.02
    methyl lactate 371.8
    butyl lactate 471.32
    diethyl carbonate 453.44
    propanediol butyl ether 453.76
    triethyl orthoformate 482.85
    p-tert-butyltoluene 334.87
    methyl 4-tert-butylbenzoate 604.7
    morpholine 1568.2
    tert-butylamine 521.9
    n-dodecanol 263.23
    dimethoxymethane 766.87
    ethylene carbonate 1120.78
    cyrene 521.4
    2-ethoxyethyl acetate 625.57
    2-ethylhexyl acetate 563.13
    1,2,4-trichlorobenzene 1541.06
    4-methylpyridine 1543.22
    dibutyl ether 614.26
    2,6-dimethyl-4-heptanol 265.55
    DEF 981.84
    dimethyl isosorbide 722.12
    tetrachloroethylene 2170.75
    eugenol 534.42
    triacetin 716.82
    span 80 528.2
    1,4-butanediol 227.35
    1,1-dichloroethane 2082.52
    2-methyl-1-pentanol 356.91
    methyl formate 760.14
    2-methyl-1-butanol 436.5
    n-decane 216.87
    butyronitrile 798.81
    3,7-dimethyl-1-octanol 416.3
    1-chlorooctane 563.29
    1-chlorotetradecane 251.02
    n-nonane 228.44
    undecane 162.45
    tert-butylcyclohexane 202.9
    cyclooctane 246.3
    cyclopentanol 1125.37
    tetrahydropyran 1683.4
    tert-amyl methyl ether 550.76
    2,5,8-trioxanonane 634.29
    1-hexene 544.07
    2-isopropoxyethanol 352.95
    2,2,2-trifluoroethanol 408.55
    methyl butyrate 769.5

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction