Triclocarban

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  • Identifiers

    CAS number
    101-20-2

    Molecular formula
    C13H9Cl3N2O

    SMILES
    C1=CC(=CC=C1NC(=O)NC2=CC(=C(C=C2)Cl)Cl)Cl

    Safety labels

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 39.03%
    Fruity 34.58%
    Grape 33.03%
    Meaty 31.16%
    Savory 27.89%
    Cheesy 27.72%
    Animal 27.35%
    Cooked 27.05%
    Ripe 26.03%
    Burnt 21.29%

     

    Flavor
    Bitter 56.09%
    Odorless 43.8%
    Mild 31.9%
    Nitrile 20.32%
    Orange flower 19.84%
    Bland 19.52%
    Very strong 19.52%
    Scallion 19.43%
    Indole 19.41%
    Sweet-like 19.32%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    5.3

    pKa est.
    7.07 (neutral)

    Molecular weight
    315.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 482 to 493 °F (NTP, 1992)
    • 491.2- 493
    • 254.4 °C
    • MP: 255.2-256 °C

    Boiling point

    • 250 °C at 97.8 kPa (733 mm Hg)

    Flash point

    • 195.91 ˚C est.

    Solubility expt.

    • less than 1 mg/mL at 79 °F (NTP, 1992)
    • Insoluble
    • In water, 0.11 mg/L at 20 °C
    • Practically insoluble in water
    • 1 g dissolves in 25 mL acetone; 3 mL dimethyl formamide
    • In methanol, 1.6 g/L at 35 °C

  • Synonyms

    • Triclocarban
    • 101-20-2
    • 1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea
    • 3,4,4'-TRICHLOROCARBANILIDE
    • Cutisan
    • Procutene
    • Solubacter
    • Cusiter
    • Genoface
    • Trilocarban
    • Urea, N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)-
    • 3,4,4'-Trichlorodiphenylurea
    • Trichlocarban
    • Triclocarbanum
    • N-(4-Chlorophenyl)-N'-(3,4-dichlorophenyl)urea
    • NSC-72005
    • TCC Soap
    • 3,4,4'-trichloro carbanilide
    • 1-(3',4'-Dichlorophenyl)-3-(4'-chlorophenyl)urea
    • ENT 26925
    • TCC (soap bacteriostat)
    • Carbanilide, 3,4,4'-trichloro-
    • CP 78416
    • N-(3,4-Dichlorophenyl)-N'-(4-chlorophenyl)urea
    • DTXSID4026214
    • BGG1Y1ED0Y
    • EPA Pesticide Chemical Code 027901
    • NSC72005
    • DTXCID906214
    • trichlorcarban
    • CHEBI:48347
    • Triclocarben
    • Dial White
    • Dial Aloe
    • Dial Odor Armor
    • Dial Aloe Aloe
    • triclorocarbanilide
    • Dial Gold Bar
    • Antibacterial Beauty
    • Dollar General Gold
    • Image Essentials Gold
    • RefChem:56162
    • Antibacterial Ocean Fresh
    • Antibacterial Golden Burst
    • Dial Odor Armor Odor Armor
    • Rite Aid Renewal Gold Deodorant
    • MegaFresh Antibacterial Deodorant
    • Coralite Ultra Antibacterial Deodorant
    • 1st Date antibacterial Deodorant (Gold)
    • 1st Date antibacterial Deodorant (Green)
    • 1st Date antibacterial Deodorant (White)
    • Dial Gold Bar Antibacterial Deodorant Soap
    • DG Body Antibacterial Deodorant 3.5 oz bar
    • 202-924-1
    • Trichlorocarbanilide
    • TCC
    • 3,4,4-Trichlorocarbanilide
    • C13H9Cl3N2O
    • 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea
    • MFCD00013254
    • NSC 72005
    • NCGC00164034-01
    • Caswell No. 874
    • Triclocarban [USAN:INN]
    • Triclocarbanum [INN-Latin]
    • CAS-101-20-2
    • CCRIS 4880
    • HSDB 5009
    • 3,?4,?4'-?Trichlorocarbanilide(Triclocarban)
    • EINECS 202-924-1
    • UNII-BGG1Y1ED0Y
    • BRN 2814890
    • AI3-26925
    • (Triclocarban)
    • Nipaguard TCC
    • TCC Triclocarbon
    • Triclocarban/TCC
    • 9EG
    • Urea,4-dichlorophenyl)-
    • Triclocarban (USP/INN)
    • TRICLOCARBAN [MI]
    • Urea-based compound, 11
    • TRICLOCARBAN [INN]
    • 3,4'-Trichlorocarbanilide
    • EC 202-924-1
    • TRICLOCARBAN [HSDB]
    • TRICLOCARBAN [USAN]
    • 3,4'-Trichlorodiphenylurea
    • cid_7547
    • NCIOpen2_008923
    • SCHEMBL68658
    • TRICLOCARBAN [MART.]
    • WLN: GR DMVMR CG DG
    • 4-12-00-01265 (Beilstein Handbook Reference)
    • MLS002415563
    • Carbanilide,4,4'-trichloro-
    • TRICLOCARBAN [USP-RS]
    • TRICLOCARBAN [WHO-DD]
    • orb1302805
    • CHEMBL1076347
    • SCHEMBL27313500
    • BDBM25730
    • Triclocarban, analytical standard
    • 3,?4,?4'-?Trichlorocarbanilide
    • HMS5085G22
    • HY-B1805
    • MSK21313
    • Tox21_112078
    • Tox21_202030
    • Tox21_300481
    • TRICLOCARBAN [USP MONOGRAPH]
    • EBC-26764
    • s6444
    • STK730440
    • 3,4,4'-Trichlorocarbanilide, 99%
    • AKOS001713711
    • Tox21_112078_1
    • CS-7760
    • DB11155
    • FT04164
    • KS-5290
    • NCGC00164034-02
    • NCGC00164034-03
    • NCGC00164034-04
    • NCGC00164034-05
    • NCGC00254243-01
    • NCGC00259579-01
    • 101-20-2

  • Applications

    Triclocarban (CAS 101-20-2) is primarily used as an antimicrobial active ingredient in consumer cosmetics and personal care products, particularly in soaps and daily body washes. It is also used in some household cleaning products as an antimicrobial additive for cleaners. Additionally, triclocarban is employed as an antimicrobial additive in certain polymers/plastics and coatings to inhibit microbial growth. In textiles, antimicrobial finishes may apply triclocarban to fabrics. Its use and regulatory status depend on local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.86
    methanol 1.44
    isopropanol 0.94
    water 0.0
    ethyl acetate 7.82
    n-propanol 2.06
    acetone 7.92
    n-butanol 2.14
    acetonitrile 1.39
    DMF 33.57
    toluene 0.78
    isobutanol 1.17
    1,4-dioxane 10.63
    methyl acetate 6.95
    THF 75.64
    2-butanone 22.56
    n-pentanol 2.96
    sec-butanol 2.43
    n-hexane 0.01
    ethylene glycol 0.05
    NMP 28.4
    cyclohexane 0.0
    DMSO 13.63
    n-butyl acetate 14.84
    n-octanol 2.95
    chloroform 8.24
    n-propyl acetate 11.04
    acetic acid 3.31
    dichloromethane 4.98
    cyclohexanone 20.01
    propylene glycol 0.65
    isopropyl acetate 7.15
    DMAc 108.92
    2-ethoxyethanol 11.95
    isopentanol 2.51
    n-heptane 0.05
    ethyl formate 5.28
    1,2-dichloroethane 2.69
    n-hexanol 3.54
    2-methoxyethanol 13.84
    isobutyl acetate 6.66
    tetrachloromethane 0.17
    n-pentyl acetate 9.64
    transcutol 67.46
    n-heptanol 3.13
    ethylbenzene 1.07
    MIBK 8.7
    2-propoxyethanol 24.16
    tert-butanol 1.92
    MTBE 3.93
    2-butoxyethanol 17.35
    propionic acid 2.3
    o-xylene 0.85
    formic acid 0.64
    diethyl ether 1.3
    m-xylene 0.68
    p-xylene 1.48
    chlorobenzene 2.13
    dimethyl carbonate 5.23
    n-octane 0.03
    formamide 1.72
    cyclopentanone 30.81
    2-pentanone 12.31
    anisole 12.63
    cyclopentyl methyl ether 5.26
    gamma-butyrolactone 25.73
    1-methoxy-2-propanol 15.91
    pyridine 16.28
    3-pentanone 7.57
    furfural 31.18
    n-dodecane 0.1
    diethylene glycol 8.5
    diisopropyl ether 0.53
    tert-amyl alcohol 3.33
    acetylacetone 19.8
    n-hexadecane 0.12
    acetophenone 15.44
    methyl propionate 8.53
    isopentyl acetate 14.3
    trichloroethylene 17.83
    n-nonanol 3.58
    cyclohexanol 1.26
    benzyl alcohol 7.91
    2-ethylhexanol 3.71
    isooctanol 3.19
    dipropyl ether 5.52
    1,2-dichlorobenzene 2.98
    ethyl lactate 9.05
    propylene carbonate 14.69
    n-methylformamide 5.44
    2-pentanol 1.42
    n-pentane 0.0
    1-propoxy-2-propanol 21.83
    1-methoxy-2-propyl acetate 29.21
    2-(2-methoxypropoxy) propanol 29.62
    mesitylene 0.46
    ε-caprolactone 21.73
    p-cymene 2.0
    epichlorohydrin 39.55
    1,1,1-trichloroethane 2.48
    2-aminoethanol 0.61
    morpholine-4-carbaldehyde 38.54
    sulfolane 26.07
    2,2,4-trimethylpentane 0.05
    2-methyltetrahydrofuran 14.21
    n-hexyl acetate 11.01
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 32.38
    sec-butyl acetate 8.5
    tert-butyl acetate 10.83
    decalin 0.05
    glycerin 1.78
    diglyme 60.06
    acrylic acid 2.19
    isopropyl myristate 6.32
    n-butyric acid 6.09
    acetyl acetate 5.26
    di(2-ethylhexyl) phthalate 8.67
    ethyl propionate 10.22
    nitromethane 10.66
    1,2-diethoxyethane 20.92
    benzonitrile 7.31
    trioctyl phosphate 4.74
    1-bromopropane 1.11
    gamma-valerolactone 63.25
    n-decanol 2.83
    triethyl phosphate 8.35
    4-methyl-2-pentanol 1.54
    propionitrile 2.54
    vinylene carbonate 11.93
    1,1,2-trichlorotrifluoroethane 27.41
    DMS 10.77
    cumene 1.0
    2-octanol 2.25
    2-hexanone 17.18
    octyl acetate 7.61
    limonene 2.64
    1,2-dimethoxyethane 44.28
    ethyl orthosilicate 7.51
    tributyl phosphate 6.77
    diacetone alcohol 16.48
    N,N-dimethylaniline 8.52
    acrylonitrile 4.33
    aniline 3.16
    1,3-propanediol 1.82
    bromobenzene 1.81
    dibromomethane 1.74
    1,1,2,2-tetrachloroethane 14.15
    2-methyl-cyclohexyl acetate 13.39
    tetrabutyl urea 13.87
    diisobutyl methanol 2.69
    2-phenylethanol 10.1
    styrene 1.44
    dioctyl adipate 12.98
    dimethyl sulfate 10.05
    ethyl butyrate 15.18
    methyl lactate 8.8
    butyl lactate 14.53
    diethyl carbonate 8.75
    propanediol butyl ether 14.18
    triethyl orthoformate 13.27
    p-tert-butyltoluene 1.92
    methyl 4-tert-butylbenzoate 19.43
    morpholine 19.04
    tert-butylamine 0.76
    n-dodecanol 2.16
    dimethoxymethane 19.73
    ethylene carbonate 7.43
    cyrene 25.57
    2-ethoxyethyl acetate 19.68
    2-ethylhexyl acetate 10.51
    1,2,4-trichlorobenzene 5.7
    4-methylpyridine 13.12
    dibutyl ether 5.78
    2,6-dimethyl-4-heptanol 2.69
    DEF 17.87
    dimethyl isosorbide 54.75
    tetrachloroethylene 4.23
    eugenol 23.02
    triacetin 17.09
    span 80 19.29
    1,4-butanediol 0.72
    1,1-dichloroethane 2.2
    2-methyl-1-pentanol 4.08
    methyl formate 4.41
    2-methyl-1-butanol 2.61
    n-decane 0.12
    butyronitrile 3.64
    3,7-dimethyl-1-octanol 4.09
    1-chlorooctane 1.25
    1-chlorotetradecane 0.66
    n-nonane 0.07
    undecane 0.11
    tert-butylcyclohexane 0.08
    cyclooctane 0.0
    cyclopentanol 1.83
    tetrahydropyran 5.52
    tert-amyl methyl ether 5.18
    2,5,8-trioxanonane 46.08
    1-hexene 0.22
    2-isopropoxyethanol 9.05
    2,2,2-trifluoroethanol 1.0
    methyl butyrate 16.15

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction