Tributyltin Chloride

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  • Identifiers

    CAS number
    1461-22-9

    Molecular formula
    C12H27ClSn

    SMILES
    CCCC[Sn](CCCC)(CCCC)Cl

    Safety labels

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Waxy 48.93%
    Oily 40.74%
    Fatty 32.8%
    Fresh 31.69%
    Floral 31.31%
    Sweet 30.29%
    Citrus 26.85%
    Fruity 26.25%
    Herbal 24.58%
    Spicy 22.55%

     

    Flavor
    Alkane 22.62%
    Mild 22.35%
    Delicate 21.75%
    Bland 21.46%
    Waxy 21.36%
    Skunky 21.26%
    Slightly waxy 20.75%
    Leathery 20.73%
    Violet-leaf 20.59%
    Bloody 20.51%

     

  • Properties

    pKa est.
    5.97 (weak acid)

    Molecular weight
    325.5 g/mol

    Boiling point

    • 171-173 °C @ 25 mm Hg

    Flash point

    • 130.51 ˚C est.

    Solubility expt.

    • Soluble in the common organic solvents, including alcohol, heptane, benzene, and toluene.
    • Insoluble in cold water but hydrolyzes in hot water

  • Synonyms

    • Tributyltin chloride
    • 1461-22-9
    • Chlorotributyltin
    • Tri-N-butyltin chloride
    • Stannane, tributylchloro-
    • Tributylchlorotin
    • Chlorotributylstannane
    • Tributyl(chloro)stannane
    • TRIBUTYLCHLOROSTANNANE
    • Chlorotri-n-butyltin
    • Tributylstannyl chloride
    • Tri-n-butylchlorotin
    • Stannane, chlorotributyl-
    • Monochlorotributyltin
    • Tributylstannium chloride
    • Tin, tri-n-butyl-, chloride
    • Chlorid tri-N-butylcinicity
    • Tri-n-butylzinn-chlorid
    • WR 3396
    • CA82T4QR5F
    • DTXSID3027403
    • NSC-22323
    • DTXCID707403
    • RefChem:190933
    • 215-958-7
    • Tributyl tinchloride
    • NSC 22323
    • Tri-n-butyl tin chloride
    • MFCD00000521
    • TRIBUTYL TIN CHLORIDE
    • TBTC (Tributyltin chloride)
    • NSC22323
    • TBTC; Tributyltin chloride
    • Caswell No. 867A
    • C12H27ClSn
    • CAS-1461-22-9
    • CCRIS 6319
    • HSDB 6816
    • Tri-N-butylzinn-chlorid [German]
    • Chlorid tri-N-butylcinicity [Czech]
    • EINECS 215-958-7
    • UNII-CA82T4QR5F
    • EPA Pesticide Chemical Code 083107
    • tributyltinchloride
    • nBu3SnCl
    • Bu3SnCl
    • SnBu3Cl
    • n-Bu3SnCl
    • tributylstannylchloride
    • chloro tri-n-butyltin
    • tri-n-butyltinchloride
    • Tributylchloro stannane
    • (Bu)3SnCl
    • (n-Bu)3SnCl
    • Tri-butyl tin chloride
    • Tri-butyl-tin-chloride
    • Chloride tri-n-butyltin
    • tri-n-butyl-tin chloride
    • tri-n-butylstannylchloride
    • chloro-tri-n-butylstannane
    • tributyl tin(IV) chloride
    • tributyl(chloranyl)stannane
    • Tri(n-butyl) tin chloride
    • tri-n-butylstannyl chloride
    • EC 215-958-7
    • SCHEMBL1131
    • tributylstannanylium;chloride
    • Tributyltin chloride, 96%
    • tri-Normal-butyltin chloride
    • CHEBI:79734
    • TRIBUTYLTIN CHLORIDE [MI]
    • WLN: G-SN-4&4&4
    • MSK21051
    • Tox21_201626
    • Tox21_300543
    • TRIBUTYLCHLOROSTANNANE [HSDB]
    • EBC-47488
    • AKOS009031150
    • FT34462
    • NCGC00164186-01
    • NCGC00164186-02
    • NCGC00164186-03
    • NCGC00254242-01
    • NCGC00259175-01
    • Tributyltin chloride, analytical standard
    • NCI60_001841
    • TBTC, PESTANAL(R), analytical standard
    • NS00081186
    • EN300-21046
    • A808453
    • Q2452578
    • Tri-n-butyltin Chloride 1000 microg/mL in Methanol
    • BRD-K88145757-001-01-6
    • F0001-0521
    • TBTC (Tributyltin chloride) 10 microg/mL in Isooctane
    • 1461-22-9

  • Applications

    Tributyltin chloride (CAS 1461-22-9) is primarily used as an organotin reagent and building block in chemical synthesis. In industry, it is employed as a precursor to tributyltin-based catalysts and stabilizers for polymer processing, including PVC stabilization and polyurethane formation, and as a tin-transfer reagent for preparing organotin species used in cross-coupling reactions (notably Stille-type couplings). It also serves as a starting material for synthesizing other organotin compounds that find use in coatings and adhesives, and, in some historical marine coating formulations, as a precursor to tributyltin biocides for antifouling paints. Overall, tributyltin chloride is treated as an intermediate or starting material under appropriate safety and regulatory controls.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 272.75
    methanol 148.38
    isopropanol 339.01
    water 0.05
    ethyl acetate 504.83
    n-propanol 402.43
    acetone 560.72
    n-butanol 467.21
    acetonitrile 146.57
    DMF 635.0
    toluene 757.5
    isobutanol 369.04
    1,4-dioxane 1124.96
    methyl acetate 368.44
    THF 3026.78
    2-butanone 618.3
    n-pentanol 353.15
    sec-butanol 407.69
    n-hexane 230.08
    ethylene glycol 29.85
    NMP 913.78
    cyclohexane 799.05
    DMSO 529.25
    n-butyl acetate 777.43
    n-octanol 417.64
    chloroform 1296.8
    n-propyl acetate 469.4
    acetic acid 159.33
    dichloromethane 929.46
    cyclohexanone 1643.49
    propylene glycol 87.64
    isopropyl acetate 528.58
    DMAc 554.91
    2-ethoxyethanol 329.31
    isopentanol 446.59
    n-heptane 498.75
    ethyl formate 273.43
    1,2-dichloroethane 706.8
    n-hexanol 585.67
    2-methoxyethanol 449.41
    isobutyl acetate 431.92
    tetrachloromethane 354.2
    n-pentyl acetate 692.62
    transcutol 858.01
    n-heptanol 404.13
    ethylbenzene 338.4
    MIBK 596.11
    2-propoxyethanol 622.74
    tert-butanol 485.43
    MTBE 688.9
    2-butoxyethanol 492.09
    propionic acid 225.06
    o-xylene 443.05
    formic acid 23.83
    diethyl ether 778.38
    m-xylene 545.15
    p-xylene 385.39
    chlorobenzene 612.93
    dimethyl carbonate 172.55
    n-octane 193.23
    formamide 47.94
    cyclopentanone 1829.01
    2-pentanone 736.89
    anisole 483.83
    cyclopentyl methyl ether 1689.92
    gamma-butyrolactone 1181.33
    1-methoxy-2-propanol 490.69
    pyridine 885.05
    3-pentanone 586.7
    furfural 794.78
    n-dodecane 97.89
    diethylene glycol 238.76
    diisopropyl ether 441.05
    tert-amyl alcohol 442.3
    acetylacetone 620.25
    n-hexadecane 114.99
    acetophenone 440.21
    methyl propionate 423.37
    isopentyl acetate 751.3
    trichloroethylene 1125.83
    n-nonanol 383.56
    cyclohexanol 850.53
    benzyl alcohol 338.09
    2-ethylhexanol 528.16
    isooctanol 381.26
    dipropyl ether 1031.47
    1,2-dichlorobenzene 555.81
    ethyl lactate 176.69
    propylene carbonate 661.75
    n-methylformamide 210.8
    2-pentanol 436.97
    n-pentane 298.77
    1-propoxy-2-propanol 704.11
    1-methoxy-2-propyl acetate 648.75
    2-(2-methoxypropoxy) propanol 320.43
    mesitylene 410.31
    ε-caprolactone 1083.41
    p-cymene 397.1
    epichlorohydrin 1149.82
    1,1,1-trichloroethane 830.67
    2-aminoethanol 101.08
    morpholine-4-carbaldehyde 809.29
    sulfolane 1330.2
    2,2,4-trimethylpentane 157.87
    2-methyltetrahydrofuran 1827.81
    n-hexyl acetate 732.7
    isooctane 146.25
    2-(2-butoxyethoxy)ethanol 464.68
    sec-butyl acetate 403.17
    tert-butyl acetate 722.98
    decalin 237.4
    glycerin 98.85
    diglyme 879.56
    acrylic acid 144.86
    isopropyl myristate 372.67
    n-butyric acid 472.98
    acetyl acetate 290.45
    di(2-ethylhexyl) phthalate 246.3
    ethyl propionate 378.05
    nitromethane 259.19
    1,2-diethoxyethane 742.6
    benzonitrile 436.34
    trioctyl phosphate 234.36
    1-bromopropane 781.21
    gamma-valerolactone 1513.61
    n-decanol 275.79
    triethyl phosphate 272.38
    4-methyl-2-pentanol 323.91
    propionitrile 297.94
    vinylene carbonate 506.04
    1,1,2-trichlorotrifluoroethane 562.42
    DMS 307.04
    cumene 247.44
    2-octanol 380.83
    2-hexanone 547.41
    octyl acetate 401.64
    limonene 690.6
    1,2-dimethoxyethane 757.01
    ethyl orthosilicate 315.23
    tributyl phosphate 250.14
    diacetone alcohol 524.34
    N,N-dimethylaniline 363.97
    acrylonitrile 253.73
    aniline 489.03
    1,3-propanediol 198.28
    bromobenzene 772.61
    dibromomethane 848.46
    1,1,2,2-tetrachloroethane 1080.8
    2-methyl-cyclohexyl acetate 571.22
    tetrabutyl urea 356.48
    diisobutyl methanol 432.78
    2-phenylethanol 433.66
    styrene 396.23
    dioctyl adipate 397.27
    dimethyl sulfate 247.12
    ethyl butyrate 602.97
    methyl lactate 174.73
    butyl lactate 419.42
    diethyl carbonate 332.09
    propanediol butyl ether 364.83
    triethyl orthoformate 530.9
    p-tert-butyltoluene 413.38
    methyl 4-tert-butylbenzoate 489.33
    morpholine 1213.64
    tert-butylamine 397.81
    n-dodecanol 218.02
    dimethoxymethane 628.24
    ethylene carbonate 510.12
    cyrene 411.55
    2-ethoxyethyl acetate 577.79
    2-ethylhexyl acetate 704.36
    1,2,4-trichlorobenzene 618.43
    4-methylpyridine 873.16
    dibutyl ether 715.13
    2,6-dimethyl-4-heptanol 432.78
    DEF 629.37
    dimethyl isosorbide 775.79
    tetrachloroethylene 685.25
    eugenol 378.24
    triacetin 460.62
    span 80 427.48
    1,4-butanediol 92.27
    1,1-dichloroethane 684.82
    2-methyl-1-pentanol 336.41
    methyl formate 173.17
    2-methyl-1-butanol 424.2
    n-decane 192.45
    butyronitrile 441.23
    3,7-dimethyl-1-octanol 435.99
    1-chlorooctane 463.3
    1-chlorotetradecane 178.04
    n-nonane 212.16
    undecane 130.01
    tert-butylcyclohexane 208.4
    cyclooctane 371.64
    cyclopentanol 841.14
    tetrahydropyran 1856.11
    tert-amyl methyl ether 617.55
    2,5,8-trioxanonane 534.45
    1-hexene 413.4
    2-isopropoxyethanol 302.28
    2,2,2-trifluoroethanol 65.03
    methyl butyrate 489.88

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction