Tributyl Phosphate

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  • Identifiers

    CAS number
    126-73-8

    Molecular formula
    C12H27O4P

    SMILES
    CCCCOP(=O)(OCCCC)OCCCC

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fruity 42.62%
    Green 41.19%
    Herbal 41.02%
    Oily 32.29%
    Apple 30.57%
    Alcoholic 29.68%
    Ethereal 28.78%
    Fresh 28.58%
    Winey 28.53%
    Fermented 28.21%

    Scent© AI

    Odor threshold>

    • Odor perception threshold 0.014 mg/L.

  • Properties

    XLogP3-AA
    2.9

    Molecular weight
    266.31 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • less than -112 °F (NTP, 1992)
    • Less than -80 °C
    • <-112 °F
    • -112 °F

    Boiling point

    • 552 °F at 760 mmHg (NTP, 1992)
    • 289 °C (decomposes)
    • 552 °F
    • 552 °F (Decomposes)

    Flash point est.
    150.08 ˚C

    Flash point expt.

    • 295 °F (NTP, 1992)
    • 146 °C
    • 146 °C (open cup)
    • 295 °F (146 °C) (Open cup)
    • 145 °C (293 °F) (Closed cup)
    • 146 °C o.c.
    • 295 °F (open cup)
    • (oc) 295 °F

    Solubility expt.

    • less than 1 mg/mL at 68.9 °F (NTP, 1992)
    • In water, 280 mg/L at 25 °C
    • Soluble in diethyl ether, benzene, carbon disulfide; miscible with ethanol
    • Miscible with most solvents and diluents
    • Solubility in water: poor
    • 0.6%

  • Synonyms

    • TRIBUTYL PHOSPHATE
    • 126-73-8
    • Tri-n-butyl phosphate
    • Tributylphosphate
    • Butyl phosphate
    • Phosphoric acid tributyl ester
    • Tributylphosphat
    • Disflamoll TB
    • Celluphos 4
    • Phosphoric acid, tributyl ester
    • Tributoxyphosphine oxide
    • tbpa
    • Tributilfosfato
    • Tributylfosfaat
    • Tributyle (phosphate de)
    • Tri-N-butylphosphate
    • Butyl phosphate, tri-
    • Butyl phosphate, ((BuO)3PO)
    • Tributylfosfat
    • Phosphoric acid tri-n-butyl ester
    • NSC 8484
    • CCRIS 6106
    • DTXSID3021986
    • HSDB 1678
    • Tributylphsophate
    • Kronitex TBP
    • UNII-95UAS8YAF5
    • EINECS 204-800-2
    • BRN 1710584
    • AI3-00399
    • Tributyl ester of phosphoric acid
    • NSC-8484
    • Syn-O-Ad 8412
    • 95UAS8YAF5
    • DTXCID701986
    • TRIBUTYL PHOSPHATE [MI]
    • CHEBI:35019
    • TRIBUTYL PHOSPHATE [HSDB]
    • NSC8484
    • EC 204-800-2
    • Phosphoric acid, tri-n-butyl ester
    • 4-01-00-01531 (Beilstein Handbook Reference)
    • TRI-N-BUTYL PHOSPHATE [MART.]
    • TRI-N-BUTYL PHOSPHATE [EP MONOGRAPH]
    • Tributylfosfat [Czech]
    • Tributylfosfaat [Dutch]
    • Tributilfosfato [Italian]
    • Tributylphosphat [German]
    • TRI-N-BUTYL PHOSPHATE (MART.)
    • CAS-126-73-8
    • TNBP
    • TRI-N-BUTYL PHOSPHATE (EP MONOGRAPH)
    • Tributyle (phosphate de) [French]
    • MCS 2495
    • Tri-n-butyl phosphate; Phosphoric acid tributyl ester
    • TriNbutylphosphate
    • Trinbutyl phosphate
    • MFCD00009436
    • Butyl phosphate, tri
    • tributylphosphoric acid
    • Tributyle(phosphate de)
    • tri-(n-butyl)-phosphate
    • tris(1-butyl) phosphate
    • Phosphate, tributyl ester
    • Tributyl phosphate, 97%
    • Tributyl phosphate, 99%
    • TRIBUTYL phosphoric acid
    • bmse000777
    • Tributyl phosphate 10 microg/mL in Cyclohexane
    • Tributyl Phosphate 1000 microg/mL in Methanol
    • Phosphate tri-N-butyl ester
    • Tri-N-butyl phosphoric acid
    • SCHEMBL18570
    • Tributyl phosphate, >=99%
    • BIDD:ER0345
    • Tributyle (phosphoric acid de)
    • CHEMBL1371096
    • MSK9048
    • Tributyl phosphate (ACGIH:OSHA)
    • LCA19626
    • BUTYL PHOSPHATE ((BUO)3PO)
    • Tox21_201872
    • Tox21_300107
    • WLN: 4OPO & O4 & O4
    • AKOS015995460
    • FT34586
    • Tributyl phosphate, analytical standard
    • PHOSPHORIC ACID, TRI-BUTYL ESTER
    • NCGC00091588-01
    • NCGC00091588-02
    • NCGC00091588-03
    • NCGC00091588-04
    • NCGC00254202-01
    • NCGC00259421-01
    • NS00010255
    • P0266
    • Tributyl phosphate, puriss., >=99.0% (GC)
    • Tributyl phosphate, SAJ first grade, >=99.0%
    • Tributyl phosphate, Selectophore(TM), >=98.0%
    • Q613394
    • F1905-7225
    • Tributyl phosphate, 10 mug/mL in hexane, analytical standard
    • Tri-n-butyl phosphate, European Pharmacopoeia (EP) Reference Standard
    • Tributyl phosphate, Pharmaceutical Secondary Standard; Certified Reference Material

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4067.95
    methanol 4638.49
    isopropanol 3129.6
    water 8.8
    ethyl acetate 2994.57
    n-propanol 3585.34
    acetone 5184.46
    n-butanol 2773.6
    acetonitrile 3480.12
    DMF 9877.26
    toluene 2893.96
    isobutanol 2740.41
    1,4-dioxane 5167.87
    methyl acetate 3506.21
    THF 7411.68
    2-butanone 4627.79
    n-pentanol 1939.17
    sec-butanol 3099.82
    n-hexane 747.28
    ethylene glycol 730.46
    NMP 10466.21
    cyclohexane 2608.01
    DMSO 6177.98
    n-butyl acetate 2775.38
    n-octanol 1342.35
    chloroform 17322.75
    n-propyl acetate 2402.09
    acetic acid 4322.3
    dichloromethane 14905.69
    cyclohexanone 9989.92
    propylene glycol 1168.42
    isopropyl acetate 2000.24
    DMAc 7847.88
    2-ethoxyethanol 2053.53
    isopentanol 2099.18
    n-heptane 525.67
    ethyl formate 2662.74
    1,2-dichloroethane 10489.91
    n-hexanol 1895.64
    2-methoxyethanol 3553.55
    isobutyl acetate 1400.06
    tetrachloromethane 2243.78
    n-pentyl acetate 2874.73
    transcutol 3281.68
    n-heptanol 1320.55
    ethylbenzene 1226.01
    MIBK 1646.69
    2-propoxyethanol 2328.57
    tert-butanol 2646.97
    MTBE 2823.23
    2-butoxyethanol 1954.89
    propionic acid 3467.0
    o-xylene 1648.74
    formic acid 1543.49
    diethyl ether 2799.27
    m-xylene 1293.15
    p-xylene 1976.79
    chlorobenzene 5163.46
    dimethyl carbonate 1422.81
    n-octane 304.38
    formamide 2806.26
    cyclopentanone 9043.08
    2-pentanone 3354.88
    anisole 1769.25
    cyclopentyl methyl ether 3712.42
    gamma-butyrolactone 8730.11
    1-methoxy-2-propanol 2416.52
    pyridine 8464.51
    3-pentanone 3218.99
    furfural 6677.27
    n-dodecane 199.37
    diethylene glycol 1241.39
    diisopropyl ether 900.19
    tert-amyl alcohol 2628.24
    acetylacetone 3068.12
    n-hexadecane 228.74
    acetophenone 2243.47
    methyl propionate 2988.35
    isopentyl acetate 2279.02
    trichloroethylene 17012.9
    n-nonanol 1135.5
    cyclohexanol 4146.75
    benzyl alcohol 1746.02
    2-ethylhexanol 1204.96
    isooctanol 1040.71
    dipropyl ether 1385.94
    1,2-dichlorobenzene 4277.7
    ethyl lactate 864.38
    propylene carbonate 4553.79
    n-methylformamide 5096.54
    2-pentanol 2024.47
    n-pentane 769.72
    1-propoxy-2-propanol 1724.97
    1-methoxy-2-propyl acetate 1693.31
    2-(2-methoxypropoxy) propanol 1022.23
    mesitylene 833.04
    ε-caprolactone 7144.4
    p-cymene 721.48
    epichlorohydrin 8584.99
    1,1,1-trichloroethane 7308.94
    2-aminoethanol 1789.32
    morpholine-4-carbaldehyde 6103.53
    sulfolane 8984.46
    2,2,4-trimethylpentane 368.0
    2-methyltetrahydrofuran 5947.83
    n-hexyl acetate 2979.41
    isooctane 212.63
    2-(2-butoxyethoxy)ethanol 1589.09
    sec-butyl acetate 1440.42
    tert-butyl acetate 1725.45
    decalin 585.53
    glycerin 1256.81
    diglyme 3200.78
    acrylic acid 3187.53
    isopropyl myristate 855.93
    n-butyric acid 4092.69
    acetyl acetate 1952.71
    di(2-ethylhexyl) phthalate 788.37
    ethyl propionate 1825.64
    nitromethane 6490.21
    1,2-diethoxyethane 1939.88
    benzonitrile 3349.28
    trioctyl phosphate 697.56
    1-bromopropane 5849.74
    gamma-valerolactone 9732.52
    n-decanol 756.47
    triethyl phosphate 743.93
    4-methyl-2-pentanol 921.94
    propionitrile 3531.05
    vinylene carbonate 4758.24
    1,1,2-trichlorotrifluoroethane 5149.08
    DMS 1882.96
    cumene 744.18
    2-octanol 1187.24
    2-hexanone 2400.47
    octyl acetate 1193.61
    limonene 1299.89
    1,2-dimethoxyethane 3899.79
    ethyl orthosilicate 718.16
    tributyl phosphate 829.6
    diacetone alcohol 1511.9
    N,N-dimethylaniline 1322.21
    acrylonitrile 4254.54
    aniline 2841.04
    1,3-propanediol 2134.04
    bromobenzene 5645.59
    dibromomethane 11009.02
    1,1,2,2-tetrachloroethane 15008.16
    2-methyl-cyclohexyl acetate 1416.36
    tetrabutyl urea 1183.39
    diisobutyl methanol 685.04
    2-phenylethanol 1472.78
    styrene 1734.61
    dioctyl adipate 1133.74
    dimethyl sulfate 2126.69
    ethyl butyrate 1625.28
    methyl lactate 1278.79
    butyl lactate 1783.57
    diethyl carbonate 1091.93
    propanediol butyl ether 1691.37
    triethyl orthoformate 1133.61
    p-tert-butyltoluene 676.21
    methyl 4-tert-butylbenzoate 1605.73
    morpholine 7135.44
    tert-butylamine 2003.71
    n-dodecanol 561.11
    dimethoxymethane 3156.87
    ethylene carbonate 4213.63
    cyrene 1228.68
    2-ethoxyethyl acetate 2395.65
    2-ethylhexyl acetate 2022.88
    1,2,4-trichlorobenzene 4609.65
    4-methylpyridine 7323.28
    dibutyl ether 1626.55
    2,6-dimethyl-4-heptanol 685.04
    DEF 5060.89
    dimethyl isosorbide 1843.92
    tetrachloroethylene 9169.3
    eugenol 1420.74
    triacetin 1824.31
    span 80 1404.06
    1,4-butanediol 984.42
    1,1-dichloroethane 8729.61
    2-methyl-1-pentanol 1494.55
    methyl formate 3224.97
    2-methyl-1-butanol 2271.14
    n-decane 357.04
    butyronitrile 3464.43
    3,7-dimethyl-1-octanol 1048.13
    1-chlorooctane 1345.48
    1-chlorotetradecane 466.47
    n-nonane 369.13
    undecane 252.61
    tert-butylcyclohexane 420.55
    cyclooctane 647.67
    cyclopentanol 4458.41
    tetrahydropyran 7138.59
    tert-amyl methyl ether 2114.49
    2,5,8-trioxanonane 1721.47
    1-hexene 1739.53
    2-isopropoxyethanol 1291.29
    2,2,2-trifluoroethanol 1630.97
    methyl butyrate 3072.21

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction