trans-10-cis-12-Octadecadienoic acid

Overview IFRA Request a quote

  • Identifiers

    CAS number
    2420-56-6

    Molecular formula
    C18H32O2

    SMILES
    CCCCC/C=C\C=C\CCCCCCCCC(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Fatty 84.18%
    Oily 58.92%
    Waxy 52.91%
    Dairy 30.44%
    Green 26.09%
    Milky 24.9%
    Creamy 23.69%
    Meaty 22.86%
    Fishy 22.72%
    Sweet 22.2%

     

    Flavor
    Fatty 41.49%
    Faint 29.39%
    Waxy 26.45%
    Slightly waxy 21.4%
    Bay oil 20.28%
    Delicate 19.98%
    Diterpene 19.53%
    Low 19.49%
    Oriental 19.44%
    Pumpkin 19.18%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.1

    pKa est.
    7.38 (neutral)

    Molecular weight
    280.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    359°C

    Flash point

    • 203.65 ˚C est.

  • Synonyms

    • 2420-56-6
    • 10-trans,12-cis-Linoleic acid
    • (10E,12Z)-10,12-Octadecadienoic acid
    • 10-TRANS-12-CIS-OCTADECADIENOIC ACID
    • trans-10-cis-12-Octadecadienoic acid
    • N151ZM4M27
    • 10,12-Octadecadienoic acid, (10E,12Z)-
    • RefChem:1100216
    • 607-342-5
    • (10E,12Z)-octadeca-10,12-dienoic acid
    • 10E,12Z-octadecadienoic acid
    • (10E,12Z)-octadecadienoic acid
    • trans-10,cis-12 conjugated linoleic acid
    • trans-10,cis-12-conjugated linoleic acid
    • 10-trans-12-cis-CLA
    • 10(E),12(Z)-Conjugated linoleic acid
    • CHEMBL1093743
    • 10-trans-12-cis-linoleic acid
    • C18:2, n-6,8 cis,trans
    • 10,12-trans,cis-octadecanoic acid
    • (E,Z)-octadeca-10,12-dienoic acid
    • trans-10, cis-12-octadecadienoic acid
    • 10-trans-12-cis-conjugated linoleic acid
    • 10E, 12Z-Linoleic acid
    • 10(e),12(z)-octadecadienoic acid
    • 10,12-Octadecadienoicacid, (10E,12Z)- (9CI)
    • C18:2n-6,8
    • 10E12Z-CLA
    • t10,c12-CLA
    • UNII-N151ZM4M27
    • Conjugated Linoleic Acid (10E,12Z)
    • (10E,12Z)-octadeca-10,12-dienoicacid
    • 10,12-Octadecadienoic acid, (Z,E)-
    • 10E,12Z-Octadecadienoate
    • SCHEMBL1810737
    • DTXSID0040628
    • CHEBI:44526
    • MSK1753
    • 10-trans-12-cis-Octadecadienoate
    • HMS3649F05
    • trans-10-cis-12-Octadecadienoate
    • BDBM50394662
    • LMFA01030125
    • 10-trans,12-cis-octadecadienoic acid
    • Conjugated (10E,12Z)-Linoleic acid
    • trans-10,cis-12-octadecadienoic acid
    • DB04746
    • (10E,12Z)-10,12-Octadecadienoate
    • trans,cis-octadeca-10,12-dienoic acid
    • ODD
    • trans-10,cis-12-conjugated-linoleic-acid
    • HY-116538
    • CS-0065803
    • NS00027586
    • 10E,12Z-CLA; 10E,12Z-octadecadienoic acid
    • F71329
    • 420C566
    • Q419936
    • SR-01000946649
    • SR-01000946649-1
    • BRD-K26222048-001-01-7
    • CONJUGATED LINOLEIC ACID (MIXTURE OF ISOMERS)
    • Conjugated (10E,12Z)-Linoleic acid, analytical standard
    • (10E,12Z)-Octadeca-10,12-dienoic acid (isomers mixture)
    • (10E,12Z)-octadeca-10,12-dienoic acid

  • Applications

    trans-10-cis-12-Octadecadienoic acid (CAS 2420-56-6) is a long-chain conjugated fatty acid used primarily as an oleochemical building block and a feedstock for downstream derivatives; in cosmetics and personal care, it serves as an emollient and conditioning ingredient; in industrial manufacturing it acts as a precursor to esterified derivatives and specialty oils and can be processed into lubricants and functional oils; in polymers and plastics it can function as a plasticizer to improve flexibility and processability in PVC and other polymers; in coatings and inks it is used as a precursor for surfactants or flow modifiers and to adjust coating performance; in agriculture or animal nutrition contexts, it may be evaluated as a lipid component in feeds, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 257.38
    methanol 184.38
    isopropanol 247.55
    water 0.01
    ethyl acetate 228.91
    n-propanol 216.06
    acetone 265.68
    n-butanol 233.79
    acetonitrile 51.33
    DMF 368.09
    toluene 84.19
    isobutanol 176.4
    1,4-dioxane 288.5
    methyl acetate 122.73
    THF 999.21
    2-butanone 269.01
    n-pentanol 206.28
    sec-butanol 218.93
    n-hexane 71.83
    ethylene glycol 7.44
    NMP 464.03
    cyclohexane 98.34
    DMSO 654.48
    n-butyl acetate 315.2
    n-octanol 98.82
    chloroform 304.59
    n-propyl acetate 293.8
    acetic acid 77.8
    dichloromethane 333.66
    cyclohexanone 538.75
    propylene glycol 37.1
    isopropyl acetate 247.52
    DMAc 507.03
    2-ethoxyethanol 284.78
    isopentanol 266.55
    n-heptane 37.97
    ethyl formate 82.64
    1,2-dichloroethane 338.57
    n-hexanol 186.98
    2-methoxyethanol 310.34
    isobutyl acetate 220.39
    tetrachloromethane 68.54
    n-pentyl acetate 269.67
    transcutol 1256.38
    n-heptanol 108.43
    ethylbenzene 81.52
    MIBK 312.26
    2-propoxyethanol 328.45
    tert-butanol 339.5
    MTBE 404.0
    2-butoxyethanol 244.35
    propionic acid 90.22
    o-xylene 79.95
    formic acid 15.32
    diethyl ether 325.98
    m-xylene 87.24
    p-xylene 95.56
    chlorobenzene 113.29
    dimethyl carbonate 44.96
    n-octane 15.22
    formamide 32.71
    cyclopentanone 525.96
    2-pentanone 343.02
    anisole 170.36
    cyclopentyl methyl ether 461.25
    gamma-butyrolactone 379.76
    1-methoxy-2-propanol 365.34
    pyridine 206.07
    3-pentanone 199.06
    furfural 260.08
    n-dodecane 9.61
    diethylene glycol 116.06
    diisopropyl ether 132.85
    tert-amyl alcohol 303.57
    acetylacetone 308.93
    n-hexadecane 11.36
    acetophenone 188.82
    methyl propionate 164.62
    isopentyl acetate 328.62
    trichloroethylene 425.96
    n-nonanol 99.89
    cyclohexanol 255.25
    benzyl alcohol 115.1
    2-ethylhexanol 152.45
    isooctanol 117.36
    dipropyl ether 276.28
    1,2-dichlorobenzene 131.74
    ethyl lactate 101.67
    propylene carbonate 203.53
    n-methylformamide 95.17
    2-pentanol 204.37
    n-pentane 37.88
    1-propoxy-2-propanol 328.99
    1-methoxy-2-propyl acetate 305.47
    2-(2-methoxypropoxy) propanol 220.08
    mesitylene 70.62
    ε-caprolactone 415.48
    p-cymene 60.86
    epichlorohydrin 521.03
    1,1,1-trichloroethane 262.13
    2-aminoethanol 49.55
    morpholine-4-carbaldehyde 374.28
    sulfolane 705.8
    2,2,4-trimethylpentane 30.67
    2-methyltetrahydrofuran 631.29
    n-hexyl acetate 295.88
    isooctane 24.74
    2-(2-butoxyethoxy)ethanol 344.58
    sec-butyl acetate 242.02
    tert-butyl acetate 350.22
    decalin 50.96
    glycerin 50.06
    diglyme 621.26
    acrylic acid 44.99
    isopropyl myristate 110.36
    n-butyric acid 252.74
    acetyl acetate 101.17
    di(2-ethylhexyl) phthalate 84.15
    ethyl propionate 213.76
    nitromethane 146.75
    1,2-diethoxyethane 476.98
    benzonitrile 109.24
    trioctyl phosphate 69.03
    1-bromopropane 250.41
    gamma-valerolactone 614.85
    n-decanol 70.65
    triethyl phosphate 108.82
    4-methyl-2-pentanol 144.24
    propionitrile 81.54
    vinylene carbonate 127.45
    1,1,2-trichlorotrifluoroethane 292.73
    DMS 126.95
    cumene 68.8
    2-octanol 87.2
    2-hexanone 334.13
    octyl acetate 127.16
    limonene 121.08
    1,2-dimethoxyethane 519.74
    ethyl orthosilicate 123.65
    tributyl phosphate 90.53
    diacetone alcohol 368.48
    N,N-dimethylaniline 144.57
    acrylonitrile 65.45
    aniline 100.81
    1,3-propanediol 117.72
    bromobenzene 128.16
    dibromomethane 254.46
    1,1,2,2-tetrachloroethane 474.04
    2-methyl-cyclohexyl acetate 227.99
    tetrabutyl urea 134.56
    diisobutyl methanol 108.04
    2-phenylethanol 128.57
    styrene 89.32
    dioctyl adipate 167.52
    dimethyl sulfate 106.78
    ethyl butyrate 244.67
    methyl lactate 85.79
    butyl lactate 188.69
    diethyl carbonate 115.65
    propanediol butyl ether 201.71
    triethyl orthoformate 195.36
    p-tert-butyltoluene 62.6
    methyl 4-tert-butylbenzoate 197.81
    morpholine 528.13
    tert-butylamine 228.79
    n-dodecanol 50.98
    dimethoxymethane 290.8
    ethylene carbonate 122.94
    cyrene 192.05
    2-ethoxyethyl acetate 292.86
    2-ethylhexyl acetate 259.66
    1,2,4-trichlorobenzene 154.93
    4-methylpyridine 234.55
    dibutyl ether 252.33
    2,6-dimethyl-4-heptanol 108.04
    DEF 354.34
    dimethyl isosorbide 433.66
    tetrachloroethylene 269.37
    eugenol 165.46
    triacetin 246.8
    span 80 208.22
    1,4-butanediol 44.32
    1,1-dichloroethane 257.9
    2-methyl-1-pentanol 214.42
    methyl formate 46.28
    2-methyl-1-butanol 216.96
    n-decane 20.24
    butyronitrile 147.92
    3,7-dimethyl-1-octanol 130.93
    1-chlorooctane 94.51
    1-chlorotetradecane 31.55
    n-nonane 19.71
    undecane 13.14
    tert-butylcyclohexane 43.99
    cyclooctane 28.94
    cyclopentanol 239.47
    tetrahydropyran 586.43
    tert-amyl methyl ether 305.92
    2,5,8-trioxanonane 387.06
    1-hexene 188.4
    2-isopropoxyethanol 257.88
    2,2,2-trifluoroethanol 21.68
    methyl butyrate 304.49

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction