Titanium isopropoxide

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  • Identifiers

    CAS number
    546-68-9

    Molecular formula
    C12H28O4Ti

    SMILES
    CC(C)[O-].CC(C)[O-].CC(C)[O-].CC(C)[O-].[Ti+4]

    Safety labels

    Flammable
    Flammable

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Alcoholic 55.15%
    Fermented 54.49%
    Ethereal 52.35%
    Solvent 49.62%
    Oily 39.43%
    Fishy 38.78%
    Musty 37.85%
    Cheesy 36.89%
    Sweet 36.83%
    Pungent 36.77%

     

    Flavor
    Fishy 42.16%
    Meaty 31.35%
    Ammoniacal 29.41%
    Sulfurous 29.12%
    Onion 27.55%
    Ammonia 23.47%
    Glue 22.46%
    Bloody 21.33%
    Yeasty 21.08%
    Gassy 20.65%

     

    Odor impact est.
    High

  • Properties

    pKa est.
    6.84 (neutral)

    Molecular weight
    284.22 g/mol

    Melting point expt.

    • Approx 20 °C

    Boiling point

    • 220 °C @ 760 mm Hg

    Flash point

    • -33.79 ˚C est.

    Solubility expt.

    • Sol in anhydrous ethanol, ether, benzene, chloroform

  • Synonyms

    • Titanium(IV) isopropoxide
    • 546-68-9
    • Titanium isopropoxide
    • Titanium isopropylate
    • Titanium tetraisopropylate
    • TETRAISOPROPYL TITANATE
    • Tilcom TIPT
    • Isopropyl orthotitanate
    • Tetraisopropoxytitanium(IV)
    • Tetraisopropoxytitanium
    • A 1 (titanate)
    • Tetraisopropanolatotitanium
    • Orgatix TA 10
    • Tetrakis(isopropoxy)titanium
    • Isopropyl titanate(IV)
    • Tyzor TPT
    • Tetraisopropoxide titanium
    • Titanium tetra-n-propoxide
    • Titanium, tetrakis(1-methylethoxy)-
    • Titanium tetrakis(isopropoxide)
    • Isopropyl alcohol, titanium salt
    • Titanic acid tetraisopropyl ester
    • Isopropyl titanate(IV) ((C3H7O)4Ti)
    • Titanium(4+) isopropoxide
    • Titanic acid isopropyl ester
    • Isopropyl alcohol, titanium(4+) salt
    • Titanic(IV) acid, tetraisopropyl ester
    • 2-Propanol, titanium(4+) salt
    • Ti(OiPr)4
    • 76NX7K235Y
    • Isopropyl alcohol titanium(4+) salt
    • CHEBI:139496
    • Titanium isopropoxide (Ti(OC3H7)4)
    • DTXSID5027196
    • ti(iv) isopropoxide
    • RefChem:897207
    • DTXCID007196
    • Titanium tetraisopropanolate
    • Tetraisopropyl orthotitanate
    • Titanium tetraisopropoxide
    • Ti Isopropylate
    • Isopropyl Titanate
    • TTIP
    • propan-2-olate;titanium(4+)
    • C12H28O4Ti
    • 2-Propanol, titanium(4+) salt (4:1)
    • Titanium(IV) Tetraisopropoxide
    • titanium(IV) propan-2-olate
    • titanium(4+) tetrakis(propan-2-olate)
    • titanium tetra(isopropoxide)
    • Titanium isopropylate (VAN)
    • TITANIUM (IV) ISOPROPOXIDE
    • HSDB 848
    • Tetraksi(isopropanolato)titanium
    • NSC-60576
    • EINECS 208-909-6
    • Titanium isopropoxide (Ti(OCH7)4)
    • NSC 60576
    • UNII-76NX7K235Y
    • TIPT
    • tetraisopropoxy titanium
    • tetraisopropoxy-titanium
    • titaniumtetraisopropoxide
    • titaniumtetraisopropylate
    • titanium(IV)isopropoxide
    • tetra-isopropoxy titanium
    • titanium (IV)isopropoxide
    • tetra-iso-propoxy titanium
    • titanium tetra-isopropoxide
    • titanium-tetra-isopropoxide
    • EC 208-909-6
    • SCHEMBL7085
    • titanium (4+) isopropoxide
    • Titanium isopropoxide(TTIP)
    • VERTEC XL 110
    • tetraisopropoxytitanium (IV)
    • titanium(IV)tetraisopropoxide
    • titanium tetra (isopropoxide)
    • titanium (IV)tetraisopropoxide
    • AKT872
    • titanium (IV) tetraisopropoxide
    • TITANUM-(IV)-ISOPROPOXIDE
    • AKOS015892702
    • FT60923
    • TITANIUM TETRAISOPROPOXIDE [MI]
    • TITANIUM TETRAISOPROPANOLATE [HSDB]
    • T0133
    • Q2031021
    • 546-68-9

  • Applications

    Titanium isopropoxide (CAS 546-68-9) is primarily used as a TiO2 precursor in sol-gel processes to form TiO2 coatings and thin films on glass, metal, and plastics; it also serves as a starting material for titanium oxide ceramics and inorganic–organic hybrids. Additionally, the compound is used to prepare TiO2 in nanoparticle form and TiO2-containing coatings for protective and functional applications, including coatings with photocatalytic and self-cleaning properties, depending on formulation and processing conditions. It can act as a Lewis acid catalyst in certain condensation and polymerization reactions, enabling processing routes in polymers and resins. In coatings/inks and electronics-related applications, TiO2 derived from titanium isopropoxide provides oxide networks and dielectric or protective layers on various surfaces. Specific applications depend on formulation and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 551.99
    methanol 1042.18
    isopropanol 406.48
    water 355.72
    ethyl acetate 133.09
    n-propanol 375.08
    acetone 306.9
    n-butanol 262.31
    acetonitrile 278.65
    DMF 472.43
    toluene 44.43
    isobutanol 233.6
    1,4-dioxane 317.23
    methyl acetate 207.84
    THF 290.57
    2-butanone 189.58
    n-pentanol 138.15
    sec-butanol 283.7
    n-hexane 66.61
    ethylene glycol 557.05
    NMP 406.31
    cyclohexane 72.01
    DMSO 244.94
    n-butyl acetate 81.24
    n-octanol 140.89
    chloroform 427.02
    n-propyl acetate 72.44
    acetic acid 692.7
    dichloromethane 264.52
    cyclohexanone 184.68
    propylene glycol 524.08
    isopropyl acetate 76.64
    DMAc 426.32
    2-ethoxyethanol 252.72
    isopentanol 153.0
    n-heptane 59.93
    ethyl formate 122.31
    1,2-dichloroethane 126.73
    n-hexanol 194.67
    2-methoxyethanol 536.44
    isobutyl acetate 48.77
    tetrachloromethane 143.59
    n-pentyl acetate 70.71
    transcutol 526.1
    n-heptanol 110.92
    ethylbenzene 31.4
    MIBK 61.71
    2-propoxyethanol 322.23
    tert-butanol 369.42
    MTBE 152.5
    2-butoxyethanol 191.82
    propionic acid 408.03
    o-xylene 48.82
    formic acid 506.93
    diethyl ether 155.67
    m-xylene 37.02
    p-xylene 44.2
    chlorobenzene 64.85
    dimethyl carbonate 77.87
    n-octane 23.54
    formamide 335.46
    cyclopentanone 232.92
    2-pentanone 114.11
    anisole 82.02
    cyclopentyl methyl ether 131.33
    gamma-butyrolactone 266.65
    1-methoxy-2-propanol 344.91
    pyridine 158.53
    3-pentanone 122.1
    furfural 235.66
    n-dodecane 21.08
    diethylene glycol 376.29
    diisopropyl ether 48.63
    tert-amyl alcohol 267.57
    acetylacetone 118.25
    n-hexadecane 21.17
    acetophenone 79.98
    methyl propionate 152.64
    isopentyl acetate 67.4
    trichloroethylene 224.15
    n-nonanol 120.61
    cyclohexanol 204.09
    benzyl alcohol 97.69
    2-ethylhexanol 98.95
    isooctanol 74.59
    dipropyl ether 105.17
    1,2-dichlorobenzene 70.23
    ethyl lactate 97.83
    propylene carbonate 131.63
    n-methylformamide 325.76
    2-pentanol 162.84
    n-pentane 71.36
    1-propoxy-2-propanol 216.49
    1-methoxy-2-propyl acetate 100.8
    2-(2-methoxypropoxy) propanol 195.5
    mesitylene 27.52
    ε-caprolactone 178.34
    p-cymene 39.85
    epichlorohydrin 186.0
    1,1,1-trichloroethane 168.98
    2-aminoethanol 576.65
    morpholine-4-carbaldehyde 382.78
    sulfolane 258.03
    2,2,4-trimethylpentane 30.12
    2-methyltetrahydrofuran 197.54
    n-hexyl acetate 130.8
    isooctane 16.94
    2-(2-butoxyethoxy)ethanol 252.47
    sec-butyl acetate 50.7
    tert-butyl acetate 80.8
    decalin 26.21
    glycerin 617.75
    diglyme 319.56
    acrylic acid 413.47
    isopropyl myristate 59.78
    n-butyric acid 250.34
    acetyl acetate 100.84
    di(2-ethylhexyl) phthalate 70.53
    ethyl propionate 82.54
    nitromethane 458.17
    1,2-diethoxyethane 120.26
    benzonitrile 88.74
    trioctyl phosphate 53.07
    1-bromopropane 90.27
    gamma-valerolactone 286.91
    n-decanol 92.29
    triethyl phosphate 48.74
    4-methyl-2-pentanol 76.78
    propionitrile 185.38
    vinylene carbonate 130.44
    1,1,2-trichlorotrifluoroethane 345.34
    DMS 114.85
    cumene 29.68
    2-octanol 76.04
    2-hexanone 78.19
    octyl acetate 83.65
    limonene 63.11
    1,2-dimethoxyethane 260.01
    ethyl orthosilicate 50.26
    tributyl phosphate 60.53
    diacetone alcohol 142.65
    N,N-dimethylaniline 72.8
    acrylonitrile 217.57
    aniline 117.09
    1,3-propanediol 407.04
    bromobenzene 48.75
    dibromomethane 180.06
    1,1,2,2-tetrachloroethane 221.06
    2-methyl-cyclohexyl acetate 72.64
    tetrabutyl urea 81.51
    diisobutyl methanol 54.69
    2-phenylethanol 102.17
    styrene 39.12
    dioctyl adipate 88.8
    dimethyl sulfate 106.65
    ethyl butyrate 69.92
    methyl lactate 174.52
    butyl lactate 97.38
    diethyl carbonate 53.7
    propanediol butyl ether 242.44
    triethyl orthoformate 61.03
    p-tert-butyltoluene 41.72
    methyl 4-tert-butylbenzoate 109.16
    morpholine 348.04
    tert-butylamine 250.33
    n-dodecanol 74.43
    dimethoxymethane 207.96
    ethylene carbonate 106.91
    cyrene 144.62
    2-ethoxyethyl acetate 99.25
    2-ethylhexyl acetate 57.54
    1,2,4-trichlorobenzene 98.77
    4-methylpyridine 126.58
    dibutyl ether 94.28
    2,6-dimethyl-4-heptanol 54.69
    DEF 169.99
    dimethyl isosorbide 184.74
    tetrachloroethylene 202.31
    eugenol 122.54
    triacetin 154.02
    span 80 215.92
    1,4-butanediol 202.68
    1,1-dichloroethane 164.79
    2-methyl-1-pentanol 88.58
    methyl formate 225.0
    2-methyl-1-butanol 169.93
    n-decane 32.05
    butyronitrile 129.31
    3,7-dimethyl-1-octanol 108.83
    1-chlorooctane 66.28
    1-chlorotetradecane 33.95
    n-nonane 32.79
    undecane 24.57
    tert-butylcyclohexane 29.57
    cyclooctane 25.21
    cyclopentanol 252.72
    tetrahydropyran 201.08
    tert-amyl methyl ether 120.44
    2,5,8-trioxanonane 263.82
    1-hexene 88.56
    2-isopropoxyethanol 159.9
    2,2,2-trifluoroethanol 346.25
    methyl butyrate 92.86

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction