Thiram

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  • Identifiers

    CAS number
    137-26-8

    Molecular formula
    C6H12N2S4

    SMILES
    CN(C)C(=S)SSC(=S)N(C)C

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Sulfurous 61.38%
    Onion 51.89%
    Garlic 43.11%
    Roasted 40.62%
    Alliaceous 39.74%
    Savory 39.21%
    Meaty 36.68%
    Cooked 36.62%
    Pungent 32.04%
    Fresh 26.59%

     

    Flavor
    Cooked 31.99%
    Onion 28.99%
    Roasted 27.83%
    Sulfurous 26.63%
    Cabbage 24.19%
    Sulfury 24.06%
    Meaty 22.82%
    Alliaceous 21.8%
    Scallion 20.99%
    Taco 20.99%

     

    Odor impact est.
    Low

    Odor threshold

    • 5 mg/cu m

  • Properties

    XLogP3-AA
    1.7

    pKa est.
    5.26 (weak acid)

    Molecular weight
    240.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 311 to 313 °F (NTP, 1992)
    • 155-156 °C
    • MP: 146 °C /Commercial grade/
    • 312 °F

    Boiling point

    • 264 °F at 20 mmHg (NTP, 1992)
    • 129 °C at 20 mm Hg
    • at 2.6kPa: 129 °C
    • 264 °F at 20 mmHg
    • Decomposes

    Flash point

    • 138.88 ˚C est.
    • 280 °F (NTP, 1992)
    • 89 °C (192 °F) (closed cup)
    • 89 °C c.c.
    • 280 °F

    Solubility expt.

    • less than 1 mg/mL at 72 °F (NTP, 1992)
    • Solubility in alcohol and in ether less than 0.2%; solubility in acetone 1.2%; in benzene 2.5%.
    • Sol in carbon disulfide
    • Solubility in ethanol <10 g/L at 25 °C, acetone 80 g/L at 25 °C, chloroform 230 g/L at 25 °C, hexane 0.04 g/L at 20 °C; dichloromethane 170 g/L at 20 °C, toluene 18 g/L at 20 °C, isopropanol 0.7 g/L at 20 °C.
    • In water, 30 mg/L at 25 °C
    • Solubility in water: none
    • 0.003%

  • Synonyms

    • thiram
    • Tetramethylthiuram disulfide
    • 137-26-8
    • Thiuram
    • Rezifilm
    • Thirame
    • TMTD
    • Pomarsol
    • Arasan
    • Fernasan
    • Nobecutan
    • Thirasan
    • Aapirol
    • Tersan
    • Tetrathiuram disulfide
    • Tetramethylthiuram
    • Tetramethylthiouram disulfide
    • Falitiram
    • Formalsol
    • Hexathir
    • Kregasan
    • Mercuram
    • Normersan
    • Sadoplon
    • Spotrete
    • Tetrasipton
    • Thillate
    • Thiramad
    • Aatiram
    • Atiram
    • Fermide
    • Fernide
    • Hermal
    • Pomasol
    • Puralin
    • Thiosan
    • Thiotox
    • Thiulin
    • Thiulix
    • Heryl
    • Pomarsol forte
    • Methyl tuads
    • Accelerator T
    • Methyl Thiram
    • Fernasan A
    • Tetramethylthiuram disulphide
    • Nocceler TT
    • Arasan-M
    • Bis(dimethylthiocarbamoyl) disulfide
    • Thiram B
    • Arasan-SF
    • Cyuram DS
    • Ekagom TB
    • Hermat TMT
    • Tetramethylenethiuram disulfide
    • Accel TMT
    • Accelerator thiuram
    • Aceto TETD
    • Radothiram
    • Royal TMTD
    • Tetramethyl-thiram disulfid
    • Fernacol
    • Sadoplon 75
    • Tetramethylthiuram bisulfide
    • Tetrapom
    • Thioknock
    • Thirampa
    • Thiramum
    • Anles
    • Arasan-SF-X
    • Aules
    • Thimer
    • Panoram 75
    • Tetramethylthiurane disulfide
    • Arasan 70
    • Arasan 75
    • Tersan 75
    • Thiram 75
    • Thiram 80
    • Spotrete-F
    • TMTDS
    • Arasan 70-S Red
    • Tetramethylthioperoxydicarbonic diamide
    • Methylthiuram disulfide
    • N,N-Tetramethylthiuram disulfide
    • Metiurac
    • Micropearls
    • Nomersan
    • Thianosan
    • Cunitex
    • Delsan
    • Thimar
    • Teramethylthiuram disulfide
    • Tersantetramethyldiurane sulfide
    • Pol-Thiuram
    • Arasan 42-S
    • Tetramethylthiurum disulfide
    • Disulfure de tetramethylthiourame
    • Tetrathiuram disulphide
    • Sranan-sf-X
    • Hy-Vic
    • SQ 1489
    • Chipco thiram 75
    • Bis(dimethyl-thiocarbamoyl)-disulfid
    • Orac TMTD
    • Tetramethylthioramdisulfide
    • Tetramethyldiurane sulphite
    • Thiotox (fungicide)
    • Disulfide, bis(dimethylthiocarbamoyl)
    • Bis((dimethylamino)carbonothioyl) disulfide
    • Fermide 850
    • Tetramethyl thiuramdisulfide
    • Tetramethylthiocarbamoyldisulphide
    • Thiuramyl
    • Thylate
    • Methyl thiuramdisulfide
    • Bis(dimethylthiocarbamyl) disulfide
    • Tetramethyl thiurane disulfide
    • Bis(dimethyl thiocarbamoyl)disulfide
    • Thirame [INN-French]
    • Thiramum [INN-Latin]
    • Thiuram D
    • Disolfuro di tetrametiltiourame
    • Tetramethyl thiurane disulphide
    • Tetramethylenethiuram disulphide
    • N,N'-(Dithiodicarbonothioyl)bis(N-methylmethanamine)
    • RCRA waste number U244
    • Flo Pro T Seed Protectant

  • Applications

    Thiram is a dithiocarbamate fungicide (CAS 137-26-8) widely used in agriculture, including as a seed-treatment fungicide to protect germinating seeds and seedlings from fungal diseases, as well as in crop-protection formulations for foliar and soil-borne diseases. In the rubber and elastomer industry, it acts as an accelerator for vulcanization, speeding curing and improving the network structure of rubber compounds. In the chemical industry, it is used as an intermediate for the synthesis of other dithiocarbamate fungicides and related rubber chemicals.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 21.73
    methanol 34.97
    isopropanol 12.56
    water 1.65
    ethyl acetate 58.26
    n-propanol 16.28
    acetone 99.29
    n-butanol 14.84
    acetonitrile 92.04
    DMF 253.17
    toluene 32.97
    isobutanol 11.63
    1,4-dioxane 137.94
    methyl acetate 88.68
    THF 224.93
    2-butanone 64.05
    n-pentanol 11.5
    sec-butanol 11.2
    n-hexane 1.11
    ethylene glycol 19.26
    NMP 464.1
    cyclohexane 7.3
    DMSO 210.88
    n-butyl acetate 55.07
    n-octanol 8.91
    chloroform 260.74
    n-propyl acetate 43.0
    acetic acid 110.2
    dichloromethane 217.8
    cyclohexanone 148.69
    propylene glycol 13.96
    isopropyl acetate 34.66
    DMAc 248.66
    2-ethoxyethanol 46.44
    isopentanol 12.64
    n-heptane 2.93
    ethyl formate 84.11
    1,2-dichloroethane 110.98
    n-hexanol 15.98
    2-methoxyethanol 93.67
    isobutyl acetate 29.06
    tetrachloromethane 50.9
    n-pentyl acetate 31.28
    transcutol 88.77
    n-heptanol 9.89
    ethylbenzene 13.57
    MIBK 27.39
    2-propoxyethanol 59.04
    tert-butanol 18.11
    MTBE 22.38
    2-butoxyethanol 33.22
    propionic acid 40.96
    o-xylene 25.54
    formic acid 82.68
    diethyl ether 23.65
    m-xylene 20.53
    p-xylene 22.98
    chlorobenzene 87.13
    dimethyl carbonate 66.39
    n-octane 1.16
    formamide 124.84
    cyclopentanone 216.05
    2-pentanone 42.77
    anisole 54.02
    cyclopentyl methyl ether 73.4
    gamma-butyrolactone 276.7
    1-methoxy-2-propanol 50.59
    pyridine 172.06
    3-pentanone 45.71
    furfural 407.45
    n-dodecane 1.11
    diethylene glycol 67.0
    diisopropyl ether 7.59
    tert-amyl alcohol 15.31
    acetylacetone 97.36
    n-hexadecane 1.32
    acetophenone 79.74
    methyl propionate 60.71
    isopentyl acetate 48.44
    trichloroethylene 313.58
    n-nonanol 9.34
    cyclohexanol 28.12
    benzyl alcohol 46.8
    2-ethylhexanol 14.75
    isooctanol 9.04
    dipropyl ether 22.62
    1,2-dichlorobenzene 103.34
    ethyl lactate 31.97
    propylene carbonate 173.9
    n-methylformamide 119.56
    2-pentanol 9.0
    n-pentane 2.0
    1-propoxy-2-propanol 41.9
    1-methoxy-2-propyl acetate 77.24
    2-(2-methoxypropoxy) propanol 43.28
    mesitylene 12.95
    ε-caprolactone 124.92
    p-cymene 19.71
    epichlorohydrin 236.87
    1,1,1-trichloroethane 138.73
    2-aminoethanol 21.29
    morpholine-4-carbaldehyde 322.58
    sulfolane 346.25
    2,2,4-trimethylpentane 1.71
    2-methyltetrahydrofuran 111.77
    n-hexyl acetate 30.94
    isooctane 1.02
    2-(2-butoxyethoxy)ethanol 44.54
    sec-butyl acetate 26.16
    tert-butyl acetate 43.9
    decalin 3.35
    glycerin 37.13
    diglyme 120.62
    acrylic acid 66.7
    isopropyl myristate 16.2
    n-butyric acid 48.3
    acetyl acetate 82.92
    di(2-ethylhexyl) phthalate 27.02
    ethyl propionate 39.17
    nitromethane 318.21
    1,2-diethoxyethane 43.63
    benzonitrile 95.77
    trioctyl phosphate 15.71
    1-bromopropane 30.34
    gamma-valerolactone 316.73
    n-decanol 7.38
    triethyl phosphate 41.41
    4-methyl-2-pentanol 6.94
    propionitrile 43.77
    vinylene carbonate 188.55
    1,1,2-trichlorotrifluoroethane 256.84
    DMS 66.23
    cumene 10.73
    2-octanol 6.53
    2-hexanone 33.5
    octyl acetate 20.96
    limonene 27.0
    1,2-dimethoxyethane 103.29
    ethyl orthosilicate 35.87
    tributyl phosphate 22.21
    diacetone alcohol 47.95
    N,N-dimethylaniline 43.24
    acrylonitrile 84.61
    aniline 59.84
    1,3-propanediol 28.69
    bromobenzene 82.52
    dibromomethane 105.29
    1,1,2,2-tetrachloroethane 235.34
    2-methyl-cyclohexyl acetate 54.2
    tetrabutyl urea 33.79
    diisobutyl methanol 11.4
    2-phenylethanol 53.35
    styrene 20.49
    dioctyl adipate 35.44
    dimethyl sulfate 139.03
    ethyl butyrate 49.4
    methyl lactate 51.74
    butyl lactate 30.01
    diethyl carbonate 44.42
    propanediol butyl ether 25.11
    triethyl orthoformate 43.76
    p-tert-butyltoluene 20.48
    methyl 4-tert-butylbenzoate 60.34
    morpholine 133.52
    tert-butylamine 10.93
    n-dodecanol 6.07
    dimethoxymethane 99.17
    ethylene carbonate 134.14
    cyrene 104.9
    2-ethoxyethyl acetate 60.32
    2-ethylhexyl acetate 43.32
    1,2,4-trichlorobenzene 146.17
    4-methylpyridine 136.5
    dibutyl ether 13.51
    2,6-dimethyl-4-heptanol 11.4
    DEF 90.2
    dimethyl isosorbide 151.88
    tetrachloroethylene 160.34
    eugenol 61.25
    triacetin 61.79
    span 80 38.6
    1,4-butanediol 13.61
    1,1-dichloroethane 82.99
    2-methyl-1-pentanol 11.13
    methyl formate 141.45
    2-methyl-1-butanol 11.67
    n-decane 1.64
    butyronitrile 39.53
    3,7-dimethyl-1-octanol 11.53
    1-chlorooctane 8.48
    1-chlorotetradecane 4.24
    n-nonane 1.39
    undecane 1.32
    tert-butylcyclohexane 2.51
    cyclooctane 2.26
    cyclopentanol 45.01
    tetrahydropyran 76.83
    tert-amyl methyl ether 22.07
    2,5,8-trioxanonane 87.66
    1-hexene 4.73
    2-isopropoxyethanol 29.02
    2,2,2-trifluoroethanol 88.04
    methyl butyrate 54.77

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction