Tetrathiane

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  • Identifiers

    CAS number
    290-81-3

    Molecular formula
    C2H4S4

    SMILES
    C1CSSSS1

  • Odor profile

    Fragrance
    Sulfurous 84.81%
    Mushroom 56.87%
    Garlic 53.08%
    Meaty 51.45%
    Onion 47.66%
    Roasted 40.83%
    Alliaceous 40.24%
    Cooked 34.89%
    Savory 31.06%
    Beefy 27.24%

     

    Flavor
    Mushroom 35.7%
    Sulfurous 30.25%
    Alliaceous 29.51%
    Roasted 28.29%
    Fishy 24.13%
    Savory 23.09%
    Alkaline 22.74%
    Meaty 22.43%
    Shrimp 22.07%
    Bouillon 21.94%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.6

    pKa est.
    2.7 (strong acid)

    Molecular weight
    156.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Very slow

    Boiling point est.
    300°C

    Flash point

    • 111.85 ˚C est.

  • Synonyms

    • tetrathiane
    • [1,2,3,4]Tetrathiane
    • 290-81-3
    • SCHEMBL4454868
    • DTXSID60343965
    • AILGMPPHXLHASV-UHFFFAOYSA-N

  • Applications

    Tetrathiane (CAS 290-81-3) is primarily used as an organosulfur building block and intermediate in chemical synthesis, acting as a sulfur source for introducing polysulfide motifs and thioether linkages into target molecules; it is also explored as a precursor for sulfur-rich polymers and crosslinking agents for plastics, coatings, and adhesives, enabling enhanced thermal and mechanical properties; in research and development, it functions as a ligand or sulfur-donor in coordination chemistry and catalytic systems; and it is used as a reagent in sulfur-chemistry studies and related applications. Handling and use are subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 8.76
    methanol 7.66
    isopropanol 8.52
    water 0.09
    ethyl acetate 89.73
    n-propanol 9.63
    acetone 136.87
    n-butanol 10.48
    acetonitrile 58.23
    DMF 308.47
    toluene 96.0
    isobutanol 8.39
    1,4-dioxane 203.55
    methyl acetate 102.87
    THF 250.43
    2-butanone 97.15
    n-pentanol 10.42
    sec-butanol 9.58
    n-hexane 5.04
    ethylene glycol 5.17
    NMP 448.99
    cyclohexane 19.35
    DMSO 238.3
    n-butyl acetate 90.11
    n-octanol 19.45
    chloroform 251.96
    n-propyl acetate 69.66
    acetic acid 41.04
    dichloromethane 225.0
    cyclohexanone 248.96
    propylene glycol 5.59
    isopropyl acetate 73.29
    DMAc 265.03
    2-ethoxyethanol 35.92
    isopentanol 11.84
    n-heptane 13.48
    ethyl formate 62.22
    1,2-dichloroethane 151.67
    n-hexanol 17.05
    2-methoxyethanol 48.34
    isobutyl acetate 50.78
    tetrachloromethane 55.61
    n-pentyl acetate 67.63
    transcutol 183.16
    n-heptanol 14.36
    ethylbenzene 49.53
    MIBK 66.63
    2-propoxyethanol 50.09
    tert-butanol 17.31
    MTBE 35.63
    2-butoxyethanol 39.5
    propionic acid 28.9
    o-xylene 78.71
    formic acid 10.23
    diethyl ether 41.83
    m-xylene 68.79
    p-xylene 68.71
    chlorobenzene 185.13
    dimethyl carbonate 83.18
    n-octane 7.71
    formamide 29.3
    cyclopentanone 343.23
    2-pentanone 85.45
    anisole 134.13
    cyclopentyl methyl ether 120.33
    gamma-butyrolactone 338.28
    1-methoxy-2-propanol 42.23
    pyridine 228.63
    3-pentanone 89.89
    furfural 483.5
    n-dodecane 7.15
    diethylene glycol 40.22
    diisopropyl ether 28.43
    tert-amyl alcohol 15.81
    acetylacetone 235.94
    n-hexadecane 8.79
    acetophenone 169.35
    methyl propionate 81.75
    isopentyl acetate 79.43
    trichloroethylene 424.87
    n-nonanol 21.34
    cyclohexanol 26.92
    benzyl alcohol 62.84
    2-ethylhexanol 24.37
    isooctanol 14.87
    dipropyl ether 58.05
    1,2-dichlorobenzene 226.71
    ethyl lactate 36.19
    propylene carbonate 192.58
    n-methylformamide 69.26
    2-pentanol 10.28
    n-pentane 4.46
    1-propoxy-2-propanol 49.54
    1-methoxy-2-propyl acetate 125.17
    2-(2-methoxypropoxy) propanol 77.46
    mesitylene 59.05
    ε-caprolactone 186.14
    p-cymene 55.72
    epichlorohydrin 278.71
    1,1,1-trichloroethane 194.29
    2-aminoethanol 7.53
    morpholine-4-carbaldehyde 409.67
    sulfolane 512.8
    2,2,4-trimethylpentane 5.11
    2-methyltetrahydrofuran 140.29
    n-hexyl acetate 80.1
    isooctane 5.0
    2-(2-butoxyethoxy)ethanol 82.36
    sec-butyl acetate 56.48
    tert-butyl acetate 102.82
    decalin 17.1
    glycerin 14.59
    diglyme 227.96
    acrylic acid 41.2
    isopropyl myristate 53.66
    n-butyric acid 40.24
    acetyl acetate 129.7
    di(2-ethylhexyl) phthalate 49.47
    ethyl propionate 70.1
    nitromethane 198.78
    1,2-diethoxyethane 108.39
    benzonitrile 154.71
    trioctyl phosphate 33.19
    1-bromopropane 52.13
    gamma-valerolactone 422.21
    n-decanol 18.32
    triethyl phosphate 67.54
    4-methyl-2-pentanol 10.56
    propionitrile 37.62
    vinylene carbonate 218.26
    1,1,2-trichlorotrifluoroethane 199.4
    DMS 136.27
    cumene 36.78
    2-octanol 13.39
    2-hexanone 69.2
    octyl acetate 56.0
    limonene 72.76
    1,2-dimethoxyethane 137.43
    ethyl orthosilicate 59.7
    tributyl phosphate 44.56
    diacetone alcohol 80.14
    N,N-dimethylaniline 99.12
    acrylonitrile 70.84
    aniline 71.15
    1,3-propanediol 12.98
    bromobenzene 234.66
    dibromomethane 134.02
    1,1,2,2-tetrachloroethane 275.48
    2-methyl-cyclohexyl acetate 83.65
    tetrabutyl urea 71.32
    diisobutyl methanol 26.5
    2-phenylethanol 66.92
    styrene 76.23
    dioctyl adipate 83.03
    dimethyl sulfate 217.21
    ethyl butyrate 94.72
    methyl lactate 48.54
    butyl lactate 46.88
    diethyl carbonate 74.85
    propanediol butyl ether 35.44
    triethyl orthoformate 78.78
    p-tert-butyltoluene 56.4
    methyl 4-tert-butylbenzoate 124.45
    morpholine 137.06
    tert-butylamine 11.51
    n-dodecanol 16.81
    dimethoxymethane 123.11
    ethylene carbonate 145.43
    cyrene 123.4
    2-ethoxyethyl acetate 114.18
    2-ethylhexyl acetate 76.0
    1,2,4-trichlorobenzene 275.08
    4-methylpyridine 212.5
    dibutyl ether 54.01
    2,6-dimethyl-4-heptanol 26.5
    DEF 133.93
    dimethyl isosorbide 233.45
    tetrachloroethylene 178.74
    eugenol 106.29
    triacetin 157.53
    span 80 69.89
    1,4-butanediol 7.54
    1,1-dichloroethane 113.11
    2-methyl-1-pentanol 12.09
    methyl formate 92.22
    2-methyl-1-butanol 9.96
    n-decane 10.3
    butyronitrile 38.43
    3,7-dimethyl-1-octanol 26.37
    1-chlorooctane 34.54
    1-chlorotetradecane 20.25
    n-nonane 9.52
    undecane 8.33
    tert-butylcyclohexane 12.58
    cyclooctane 12.75
    cyclopentanol 35.25
    tetrahydropyran 107.5
    tert-amyl methyl ether 37.89
    2,5,8-trioxanonane 184.52
    1-hexene 13.89
    2-isopropoxyethanol 32.14
    2,2,2-trifluoroethanol 36.05
    methyl butyrate 87.47

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction