Tetramethyl hexaphenyl tetrasiloxane

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  • Identifiers

    CAS number
    38421-40-8

    Molecular formula
    C40H42O3Si4

    SMILES
    C[Si](C1=CC=CC=C1)(C2=CC=CC=C2)O[Si](C)(C3=CC=CC=C3)O[Si](C)(C4=CC=CC=C4)O[Si](C)(C5=CC=CC=C5)C6=CC=CC=C6

    Safety labels

  • Odor profile

    Fragrance
    Floral 65.22%
    Rose 49.0%
    Green 48.6%
    Fruity 45.69%
    Balsamic 39.35%
    Sweet 33.74%
    Fresh 31.28%
    Metallic 25.84%
    Earthy 24.79%
    Hyacinth 23.86%

     

    Flavor
    Bitter 44.8%
    Green 36.09%
    Fruity 35.62%
    Floral 29.29%
    Rose 25.21%
    Sweet 23.85%
    Waxy 20.91%
    Earthy 20.43%
    Mild 19.55%
    Herbal 19.27%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.38 (weak acid)

    Molecular weight
    683.1 g/mol

    Flash point

    • 227.97 ˚C est.

  • Synonyms

    • 1,3,5,7-Tetramethyl-1,1,3,5,7,7-hexaphenyltetrasiloxane
    • 38421-40-8
    • EINECS 253-922-2
    • Q0A43X3I6V
    • tetramethyl hexaphenyl tetrasiloxane
    • DTXSID20959324
    • Tetrasiloxane, 1,3,5,7-tetramethyl-1,1,3,5,7,7-hexaphenyl-
    • RefChem:897312
    • DTXCID801387207
    • TETRAMETHYL HEXAPHENYL TETRASILOXANE [INCI]
    • Tetrasiloxane, 1,3,5,7tetramethyl1,1,3,5,7,7hexaphenyl
    • 253-922-2
    • UNII-Q0A43X3I6V
    • SCHEMBL14649161
    • XQVNZAVBAUQQHU-UHFFFAOYSA-N
    • NS00057184
    • 1,3,5,7-tetramethyl-1,1,3,5,7,7-hexaphenyl-tetrasiloxane
    • 38421-40-8

  • Applications

    Tetramethyl hexaphenyl tetrasiloxane is a specialty organosilicon compound often used as an intermediate and additive in high-performance silicone formulations. Owing to its phenyl substituents, the compound can improve thermal stability and compatibility within silicone networks, and influence refractive properties. Common applications include use as an end-capping or crosslinking intermediate in silicone resins or elastomers, as a heat-stabilizing and gloss-enhancing additive in coatings and inks, as a dielectric or encapsulant component in electronics packaging, as a surface-treatment aid or processing additive in polymer systems, and as a processing aid in industrial formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 3.45
    methanol 2.13
    isopropanol 2.3
    water 0.01
    ethyl acetate 19.49
    n-propanol 5.81
    acetone 11.26
    n-butanol 5.82
    acetonitrile 2.83
    DMF 49.69
    toluene 23.2
    isobutanol 4.18
    1,4-dioxane 23.08
    methyl acetate 13.33
    THF 125.89
    2-butanone 24.52
    n-pentanol 5.31
    sec-butanol 5.37
    n-hexane 1.62
    ethylene glycol 0.41
    NMP 150.24
    cyclohexane 2.54
    DMSO 20.3
    n-butyl acetate 22.02
    n-octanol 4.45
    chloroform 156.35
    n-propyl acetate 15.15
    acetic acid 7.19
    dichloromethane 125.17
    cyclohexanone 55.16
    propylene glycol 1.31
    isopropyl acetate 16.3
    DMAc 87.43
    2-ethoxyethanol 7.99
    isopentanol 4.79
    n-heptane 2.53
    ethyl formate 10.27
    1,2-dichloroethane 45.09
    n-hexanol 6.47
    2-methoxyethanol 10.4
    isobutyl acetate 11.48
    tetrachloromethane 12.7
    n-pentyl acetate 21.85
    transcutol 14.91
    n-heptanol 6.24
    ethylbenzene 10.35
    MIBK 15.03
    2-propoxyethanol 17.42
    tert-butanol 2.71
    MTBE 9.83
    2-butoxyethanol 14.87
    propionic acid 8.59
    o-xylene 11.0
    formic acid 2.14
    diethyl ether 13.08
    m-xylene 11.9
    p-xylene 10.24
    chlorobenzene 42.31
    dimethyl carbonate 15.68
    n-octane 0.89
    formamide 4.3
    cyclopentanone 96.79
    2-pentanone 24.7
    anisole 21.39
    cyclopentyl methyl ether 49.59
    gamma-butyrolactone 93.82
    1-methoxy-2-propanol 11.28
    pyridine 56.4
    3-pentanone 24.1
    furfural 62.8
    n-dodecane 0.55
    diethylene glycol 4.15
    diisopropyl ether 4.3
    tert-amyl alcohol 6.02
    acetylacetone 24.69
    n-hexadecane 0.65
    acetophenone 24.2
    methyl propionate 24.82
    isopentyl acetate 20.4
    trichloroethylene 147.4
    n-nonanol 5.3
    cyclohexanol 8.94
    benzyl alcohol 10.78
    2-ethylhexanol 7.29
    isooctanol 5.6
    dipropyl ether 17.19
    1,2-dichlorobenzene 40.44
    ethyl lactate 7.79
    propylene carbonate 44.64
    n-methylformamide 12.88
    2-pentanol 4.72
    n-pentane 1.53
    1-propoxy-2-propanol 15.85
    1-methoxy-2-propyl acetate 29.43
    2-(2-methoxypropoxy) propanol 13.24
    mesitylene 5.73
    ε-caprolactone 55.72
    p-cymene 7.26
    epichlorohydrin 102.69
    1,1,1-trichloroethane 41.39
    2-aminoethanol 1.85
    morpholine-4-carbaldehyde 63.77
    sulfolane 113.23
    2,2,4-trimethylpentane 1.34
    2-methyltetrahydrofuran 63.76
    n-hexyl acetate 19.06
    isooctane 0.63
    2-(2-butoxyethoxy)ethanol 13.42
    sec-butyl acetate 13.05
    tert-butyl acetate 17.71
    decalin 1.8
    glycerin 2.35
    diglyme 27.92
    acrylic acid 7.93
    isopropyl myristate 8.12
    n-butyric acid 15.04
    acetyl acetate 12.73
    di(2-ethylhexyl) phthalate 9.88
    ethyl propionate 18.32
    nitromethane 16.25
    1,2-diethoxyethane 13.65
    benzonitrile 14.32
    trioctyl phosphate 6.57
    1-bromopropane 32.62
    gamma-valerolactone 104.36
    n-decanol 3.6
    triethyl phosphate 11.95
    4-methyl-2-pentanol 3.15
    propionitrile 6.65
    vinylene carbonate 41.05
    1,1,2-trichlorotrifluoroethane 57.83
    DMS 17.73
    cumene 5.64
    2-octanol 4.41
    2-hexanone 17.54
    octyl acetate 10.84
    limonene 11.13
    1,2-dimethoxyethane 20.52
    ethyl orthosilicate 11.88
    tributyl phosphate 7.48
    diacetone alcohol 14.04
    N,N-dimethylaniline 16.99
    acrylonitrile 8.43
    aniline 17.01
    1,3-propanediol 2.97
    bromobenzene 51.99
    dibromomethane 72.94
    1,1,2,2-tetrachloroethane 103.24
    2-methyl-cyclohexyl acetate 19.76
    tetrabutyl urea 13.91
    diisobutyl methanol 4.04
    2-phenylethanol 12.97
    styrene 12.42
    dioctyl adipate 14.22
    dimethyl sulfate 36.54
    ethyl butyrate 21.78
    methyl lactate 10.84
    butyl lactate 14.48
    diethyl carbonate 12.31
    propanediol butyl ether 7.74
    triethyl orthoformate 18.79
    p-tert-butyltoluene 6.83
    methyl 4-tert-butylbenzoate 26.29
    morpholine 35.68
    tert-butylamine 2.1
    n-dodecanol 2.55
    dimethoxymethane 27.28
    ethylene carbonate 28.43
    cyrene 23.82
    2-ethoxyethyl acetate 26.18
    2-ethylhexyl acetate 20.8
    1,2,4-trichlorobenzene 51.82
    4-methylpyridine 49.07
    dibutyl ether 8.55
    2,6-dimethyl-4-heptanol 4.04
    DEF 40.12
    dimethyl isosorbide 39.86
    tetrachloroethylene 50.22
    eugenol 18.32
    triacetin 18.23
    span 80 14.28
    1,4-butanediol 1.24
    1,1-dichloroethane 36.27
    2-methyl-1-pentanol 5.88
    methyl formate 10.16
    2-methyl-1-butanol 6.6
    n-decane 1.16
    butyronitrile 8.13
    3,7-dimethyl-1-octanol 4.74
    1-chlorooctane 5.66
    1-chlorotetradecane 2.05
    n-nonane 0.99
    undecane 0.75
    tert-butylcyclohexane 1.48
    cyclooctane 1.27
    cyclopentanol 13.87
    tetrahydropyran 37.9
    tert-amyl methyl ether 14.21
    2,5,8-trioxanonane 18.51
    1-hexene 6.05
    2-isopropoxyethanol 6.82
    2,2,2-trifluoroethanol 4.6
    methyl butyrate 22.46

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction