Tetrahydrofurfuryl palmitate

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  • Identifiers

    CAS number
    105-26-0

    Molecular formula
    C21H40O3

    SMILES
    CCCCCCCCCCCCCCCC(=O)OCC1CCCO1

    Safety labels

  • Odor profile

    Fragrance
    Fatty 72.93%
    Waxy 67.48%
    Oily 55.75%
    Creamy 37.42%
    Sweet 35.33%
    Buttery 31.68%
    Dairy 28.93%
    Fruity 27.42%
    Odorless 27.16%
    Milky 26.67%

     

    Flavor
    Waxy 66.82%
    Fatty 58.43%
    Oily 54.55%
    Creamy 44.68%
    Fruity 41.92%
    Coconut 40.95%
    Mild 39.49%
    Soapy 36.43%
    Sweet 36.1%
    Fat 33.8%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.8

    pKa est.
    7.08 (neutral)

    Molecular weight
    340.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    411°C

    Flash point

    • 178.45 ˚C est.

  • Synonyms

    • oxolan-2-ylmethyl hexadecanoate
    • 105-26-0
    • Tetrahydrofurfuryl palmitate
    • Hexadecanoic acid, (tetrahydro-2-furanyl)methyl ester
    • (oxolan-2-yl)methyl hexadecanoate
    • EINECS 203-282-5
    • Palmitic acid, tetrahydrofurfuryl ester
    • SCHEMBL3085045
    • NSC4908
    • CUKYEOCBCKJPPB-UHFFFAOYSA-N
    • DTXSID401216270
    • NSC 4908
    • NSC-4908
    • DB-255899
    • NS00041367
    • 105-26-0

  • Applications

    Tetrahydrofurfuryl palmitate (CAS 105-26-0) is used in cosmetics and personal care as a non-greasy emollient and conditioning agent for skin and hair, improving spreadability and texture in creams, lotions, and hair care formulations. It also serves as a solvent and solubilizer for fragrance components and active ingredients within formulations. In polymers and coatings, it may function as a plasticizer or processing aid to enhance flexibility of films and ease of processing. It can also act as a solvent or diluent in cleaning and household formulations and as a compatible ester-based component in coatings and inks, with the exact role depending on the formulation and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 113.01
    methanol 123.86
    isopropanol 149.36
    water 0.14
    ethyl acetate 1155.93
    n-propanol 164.63
    acetone 622.62
    n-butanol 225.75
    acetonitrile 326.45
    DMF 591.66
    toluene 355.41
    isobutanol 183.92
    1,4-dioxane 766.47
    methyl acetate 640.82
    THF 1650.58
    2-butanone 761.99
    n-pentanol 159.97
    sec-butanol 215.14
    n-hexane 60.78
    ethylene glycol 9.93
    NMP 1281.41
    cyclohexane 362.33
    DMSO 730.76
    n-butyl acetate 955.3
    n-octanol 185.65
    chloroform 2780.47
    n-propyl acetate 1238.02
    acetic acid 304.85
    dichloromethane 3042.18
    cyclohexanone 2100.58
    propylene glycol 27.52
    isopropyl acetate 1086.83
    DMAc 1161.31
    2-ethoxyethanol 358.33
    isopentanol 301.31
    n-heptane 64.58
    ethyl formate 446.18
    1,2-dichloroethane 1791.69
    n-hexanol 147.01
    2-methoxyethanol 331.63
    isobutyl acetate 774.94
    tetrachloromethane 563.0
    n-pentyl acetate 1231.22
    transcutol 1738.4
    n-heptanol 168.46
    ethylbenzene 236.82
    MIBK 770.7
    2-propoxyethanol 334.31
    tert-butanol 294.46
    MTBE 581.02
    2-butoxyethanol 455.03
    propionic acid 301.09
    o-xylene 307.65
    formic acid 53.96
    diethyl ether 497.14
    m-xylene 262.34
    p-xylene 376.76
    chlorobenzene 712.89
    dimethyl carbonate 213.7
    n-octane 33.23
    formamide 132.36
    cyclopentanone 1803.3
    2-pentanone 901.24
    anisole 515.43
    cyclopentyl methyl ether 999.52
    gamma-butyrolactone 1860.0
    1-methoxy-2-propanol 383.39
    pyridine 967.5
    3-pentanone 721.08
    furfural 1137.67
    n-dodecane 21.66
    diethylene glycol 124.99
    diisopropyl ether 263.28
    tert-amyl alcohol 337.44
    acetylacetone 1197.82
    n-hexadecane 27.66
    acetophenone 690.15
    methyl propionate 668.84
    isopentyl acetate 936.11
    trichloroethylene 2959.97
    n-nonanol 187.42
    cyclohexanol 535.78
    benzyl alcohol 286.81
    2-ethylhexanol 200.11
    isooctanol 197.43
    dipropyl ether 463.22
    1,2-dichlorobenzene 862.97
    ethyl lactate 326.14
    propylene carbonate 1164.86
    n-methylformamide 253.22
    2-pentanol 215.05
    n-pentane 45.44
    1-propoxy-2-propanol 403.1
    1-methoxy-2-propyl acetate 802.55
    2-(2-methoxypropoxy) propanol 401.42
    mesitylene 213.22
    ε-caprolactone 1903.07
    p-cymene 189.51
    epichlorohydrin 1848.6
    1,1,1-trichloroethane 2080.38
    2-aminoethanol 42.5
    morpholine-4-carbaldehyde 975.45
    sulfolane 2040.38
    2,2,4-trimethylpentane 51.86
    2-methyltetrahydrofuran 1385.62
    n-hexyl acetate 1050.32
    isooctane 29.88
    2-(2-butoxyethoxy)ethanol 534.03
    sec-butyl acetate 955.99
    tert-butyl acetate 1162.09
    decalin 116.95
    glycerin 52.24
    diglyme 1433.86
    acrylic acid 183.19
    isopropyl myristate 314.73
    n-butyric acid 834.27
    acetyl acetate 814.76
    di(2-ethylhexyl) phthalate 231.05
    ethyl propionate 1011.26
    nitromethane 853.92
    1,2-diethoxyethane 937.32
    benzonitrile 535.64
    trioctyl phosphate 170.03
    1-bromopropane 928.37
    gamma-valerolactone 2156.1
    n-decanol 117.02
    triethyl phosphate 423.02
    4-methyl-2-pentanol 175.73
    propionitrile 361.1
    vinylene carbonate 861.38
    1,1,2-trichlorotrifluoroethane 1036.31
    DMS 555.84
    cumene 179.65
    2-octanol 172.86
    2-hexanone 795.69
    octyl acetate 381.82
    limonene 346.83
    1,2-dimethoxyethane 1030.76
    ethyl orthosilicate 414.79
    tributyl phosphate 256.72
    diacetone alcohol 720.06
    N,N-dimethylaniline 333.56
    acrylonitrile 362.8
    aniline 338.59
    1,3-propanediol 119.42
    bromobenzene 892.69
    dibromomethane 1767.26
    1,1,2,2-tetrachloroethane 2606.13
    2-methyl-cyclohexyl acetate 668.1
    tetrabutyl urea 360.65
    diisobutyl methanol 163.85
    2-phenylethanol 256.16
    styrene 298.14
    dioctyl adipate 498.0
    dimethyl sulfate 439.89
    ethyl butyrate 996.65
    methyl lactate 203.7
    butyl lactate 589.94
    diethyl carbonate 563.1
    propanediol butyl ether 290.08
    triethyl orthoformate 690.23
    p-tert-butyltoluene 167.27
    methyl 4-tert-butylbenzoate 653.4
    morpholine 986.41
    tert-butylamine 197.56
    n-dodecanol 82.32
    dimethoxymethane 463.96
    ethylene carbonate 899.08
    cyrene 410.41
    2-ethoxyethyl acetate 1151.37
    2-ethylhexyl acetate 796.81
    1,2,4-trichlorobenzene 1002.73
    4-methylpyridine 990.62
    dibutyl ether 574.02
    2,6-dimethyl-4-heptanol 163.85
    DEF 1094.06
    dimethyl isosorbide 879.11
    tetrachloroethylene 1657.74
    eugenol 460.17
    triacetin 1013.61
    span 80 368.4
    1,4-butanediol 53.13
    1,1-dichloroethane 1579.57
    2-methyl-1-pentanol 227.73
    methyl formate 189.88
    2-methyl-1-butanol 262.21
    n-decane 50.47
    butyronitrile 467.01
    3,7-dimethyl-1-octanol 225.87
    1-chlorooctane 272.83
    1-chlorotetradecane 82.9
    n-nonane 47.86
    undecane 30.5
    tert-butylcyclohexane 73.06
    cyclooctane 82.79
    cyclopentanol 460.36
    tetrahydropyran 1312.41
    tert-amyl methyl ether 515.94
    2,5,8-trioxanonane 777.8
    1-hexene 185.97
    2-isopropoxyethanol 358.28
    2,2,2-trifluoroethanol 180.19
    methyl butyrate 1413.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction