Tetraethylenepentamine

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  • Identifiers

    CAS number
    112-57-2

    Molecular formula
    C8H23N5

    SMILES
    C(CNCCNCCNCCN)N

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Fishy 80.84%
    Odorless 39.34%
    Ripe 33.86%
    Cheesy 33.13%
    Animal 26.85%
    Savory 18.18%
    Meaty 17.52%
    Pungent 14.9%
    Oily 14.41%
    Alcoholic 13.64%

     

    Flavor
    Odorless 32.07%
    Ammoniacal 22.02%
    Bland 21.73%
    Fishy 20.48%
    Sulfurous 18.9%
    Sweet-like 18.52%
    Glue 18.08%
    Rotten 18.08%
    Alkaline 18.01%
    Skunky 17.64%

     

    Odor impact est.
    Low

    Odor threshold

    • Odor Threshold Low: 0.1 [mg/m3]. [HSDB] Odor threshold low from CHEMINFO

  • Properties

    XLogP3-AA
    -2.9

    pKa est.
    5.87 (weak acid)

    Molecular weight
    189.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • -40 °F (NTP, 1992)
    • FP: -30 °C
    • -46 - -30 °C

    Boiling point

    • 644 °F at 760 mmHg (NTP, 1992)
    • 340.30 °C @ 760 MM HG
    • 320 - 340 °C

    Flash point

    • 177.3 ˚C est.
    • 325 °F (NTP, 1992)
    • 163 °C
    • 325 °F (163 °C) (OPEN CUP)
    • 163 °C o.c.

    Solubility expt.

    • greater than or equal to 100 mg/mL at 72 °F (NTP, 1992)
    • SOL IN MOST ORGANIC SOLVENTS & WATER
    • Solubility in water: miscible

  • Synonyms

    • TETRAETHYLENEPENTAMINE
    • 112-57-2
    • Tetren
    • 1,4,7,10,13-Pentaazatridecane
    • Tetraethylpentylamine
    • Tetraethylene pentamine
    • 1,11-Diamino-3,6,9-triazaundecane
    • 3,6,9-Triazaundecamethylenediamine
    • DEH 26
    • 3,6,9-Triazaundecane-1,11-diamine
    • Ancamine TEPA
    • TETRAEN
    • YZD1C9KQ28
    • DTXSID7026108
    • INSULCURE 9
    • 1,2-Ethanediamine, N-(2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-
    • NSC-88603
    • 1,2-Ethanediamine, N-(2-aminoethyl)-N'-(2-((2-aminoethyl)amino)ethyl)-
    • DTXCID006108
    • CHEBI:49798
    • N-(2-Aminoethyl)-N-(2-((2-aminoethyl)amino)ethyl-1,2-ethanediamine)
    • TH 160
    • n-(2-aminoethyl)-n'-(2-((2-aminoethyl)amino)ethyl)-1,2-ethanediamine
    • 3,6,9-TRIAZA-1,11-DIAMINOUNDECANE
    • 1,2-Ethanediamine, N1-(2-aminoethyl)-N2-(2-((2-aminoethyl)amino)ethyl)-
    • T-11509
    • 1,2-Ethanediamine, N1-(2-aminoethyl)-N2-[2-[(2-aminoethyl)amino]ethyl]-
    • RefChem:188579
    • 203-986-2
    • 682-669-4
    • Tetrene
    • MFCD00008168
    • NSC 88603
    • 26913-06-4
    • N'-[2-[2-(2-aminoethylamino)ethylamino]ethyl]ethane-1,2-diamine
    • (2-aminoethyl)[2-({2-[(2-aminoethyl)amino]ethyl}amino)ethyl]amine
    • NCGC00090964-02
    • N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine
    • CAS-112-57-2
    • PAW
    • CCRIS 6275
    • HSDB 5171
    • EINECS 203-986-2
    • UN2320
    • UNII-YZD1C9KQ28
    • BRN 0506966
    • AI3-10049
    • C8H23N5
    • Tetraethylenpentamine
    • Texlin 400
    • tetraethylene pentaamine
    • 1,6,9-triazaundecane
    • Tetraethylenepentamine, CP
    • Tetraethylenepentamine [UN2320] [Corrosive]
    • NCIOpen2_001402
    • SCHEMBL15797
    • Tetraethylenepentamine polymer
    • WLN: Z2M2M2M2Z
    • 4-04-00-01244 (Beilstein Handbook Reference)
    • MLS000028888
    • BIDD:ER0305
    • CHEMBL138297
    • SCHEMBL2201186
    • 1,7,10,13-Pentaazatridecane
    • Tetraethylenepentamine, tech grade
    • 3,9-Triazaundecane-1,11-diamine
    • NSC88603
    • TETRAETHYLENEPENTAMINE [HSDB]
    • Tox21_111047
    • Tox21_200669
    • D.E.H. 26
    • EBC-44082
    • SBB060752
    • STL453738
    • AKOS015894482
    • Tetraethylenepentamine, technical grade
    • Tox21_111047_1
    • UN 2320
    • NCGC00090964-01
    • NCGC00090964-03
    • NCGC00090964-04
    • NCGC00258223-01
    • FT106450
    • SMR000059212
    • NS00009971
    • ST51046872
    • T0098
    • BIS(2-(2-AMINOETHYLAMINO)ETHYL)AMINE
    • EN300-268351
    • Tetraethylenepentamine [UN2320] [Corrosive]
    • AB00375928_03
    • F095105
    • SR-01000944425
    • SR-01000944425-1
    • BRD-K41298358-395-01-8
    • BRD-K41298358-395-02-6
    • BRD-K41298358-395-03-4
    • Q15974770
    • 1, N-(2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-
    • ethane, 1-(2-aminoethyl)amino-2-[2-(2-aminoethyl)aminoethyl]amino-
    • N~1~,N~1'~-[Azanediyldi(ethane-2,1-diyl)]di(ethane-1,2-diamine)
    • N1-{2-[2-(2-AMINO-ETHYLAMINO)-ETHYLAMINO]-ETHYL}-ETHANE-1,2-DIAMINE
    • 27233-92-7
    • 112-57-2

  • Applications

    Tetraethylenepentamine (TEPA), CAS 112-57-2, is used primarily as a curing agent for epoxy resins in coatings, adhesives, and composite formulations, where it provides crosslinking and improves thermal and mechanical properties. It also serves as an intermediate for the manufacture of surfactants and specialty cleaners. In water treatment and oilfield applications, TEPA acts as a corrosion inhibitor and may participate in metal complexation or scale inhibition due to its multiple amine sites. It is also used as a ligand/chelating agent for metals in industrial processes and as a building block for polyamine resins and related crosslinked polymers. The exact use depends on formulation and regulatory constraints; TEPA should be used in accordance with local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 39.64
    methanol 208.91
    isopropanol 7.53
    water 1061.96
    ethyl acetate 3.96
    n-propanol 23.85
    acetone 3.25
    n-butanol 12.56
    acetonitrile 4.11
    DMF 71.01
    toluene 0.86
    isobutanol 9.19
    1,4-dioxane 8.67
    methyl acetate 4.16
    THF 20.03
    2-butanone 3.49
    n-pentanol 5.67
    sec-butanol 5.94
    n-hexane 0.31
    ethylene glycol 210.45
    NMP 184.67
    cyclohexane 0.97
    DMSO 222.52
    n-butyl acetate 4.74
    n-octanol 2.07
    chloroform 10.14
    n-propyl acetate 3.08
    acetic acid 301.73
    dichloromethane 10.01
    cyclohexanone 15.76
    propylene glycol 90.63
    isopropyl acetate 1.78
    DMAc 53.1
    2-ethoxyethanol 37.66
    isopentanol 4.78
    n-heptane 0.85
    ethyl formate 18.71
    1,2-dichloroethane 6.11
    n-hexanol 6.53
    2-methoxyethanol 122.41
    isobutyl acetate 1.59
    tetrachloromethane 4.7
    n-pentyl acetate 2.67
    transcutol 31.26
    n-heptanol 4.45
    ethylbenzene 0.36
    MIBK 0.91
    2-propoxyethanol 35.34
    tert-butanol 4.07
    MTBE 0.78
    2-butoxyethanol 22.54
    propionic acid 82.9
    o-xylene 0.93
    formic acid 1127.72
    diethyl ether 1.42
    m-xylene 0.64
    p-xylene 0.53
    chlorobenzene 2.36
    dimethyl carbonate 5.74
    n-octane 0.3
    formamide 600.21
    cyclopentanone 27.95
    2-pentanone 2.37
    anisole 1.05
    cyclopentyl methyl ether 6.69
    gamma-butyrolactone 72.45
    1-methoxy-2-propanol 36.72
    pyridine 12.58
    3-pentanone 2.74
    furfural 103.74
    n-dodecane 0.14
    diethylene glycol 82.54
    diisopropyl ether 0.36
    tert-amyl alcohol 4.66
    acetylacetone 4.06
    n-hexadecane 0.14
    acetophenone 2.93
    methyl propionate 7.28
    isopentyl acetate 2.93
    trichloroethylene 12.4
    n-nonanol 1.94
    cyclohexanol 11.84
    benzyl alcohol 6.06
    2-ethylhexanol 3.11
    isooctanol 2.69
    dipropyl ether 2.63
    1,2-dichlorobenzene 3.19
    ethyl lactate 11.37
    propylene carbonate 29.44
    n-methylformamide 131.45
    2-pentanol 3.15
    n-pentane 0.39
    1-propoxy-2-propanol 17.78
    1-methoxy-2-propyl acetate 7.29
    2-(2-methoxypropoxy) propanol 8.54
    mesitylene 0.47
    ε-caprolactone 23.19
    p-cymene 1.04
    epichlorohydrin 25.69
    1,1,1-trichloroethane 2.47
    2-aminoethanol 176.63
    morpholine-4-carbaldehyde 95.18
    sulfolane 217.78
    2,2,4-trimethylpentane 0.23
    2-methyltetrahydrofuran 7.7
    n-hexyl acetate 2.28
    isooctane 0.09
    2-(2-butoxyethoxy)ethanol 14.72
    sec-butyl acetate 1.39
    tert-butyl acetate 1.57
    decalin 0.28
    glycerin 303.84
    diglyme 24.3
    acrylic acid 147.08
    isopropyl myristate 0.74
    n-butyric acid 59.9
    acetyl acetate 4.97
    di(2-ethylhexyl) phthalate 3.19
    ethyl propionate 3.05
    nitromethane 105.94
    1,2-diethoxyethane 2.77
    benzonitrile 4.17
    trioctyl phosphate 2.58
    1-bromopropane 1.86
    gamma-valerolactone 67.1
    n-decanol 1.31
    triethyl phosphate 4.93
    4-methyl-2-pentanol 1.13
    propionitrile 4.76
    vinylene carbonate 33.99
    1,1,2-trichlorotrifluoroethane 150.69
    DMS 4.39
    cumene 0.4
    2-octanol 1.44
    2-hexanone 1.55
    octyl acetate 1.4
    limonene 1.45
    1,2-dimethoxyethane 14.06
    ethyl orthosilicate 4.26
    tributyl phosphate 3.39
    diacetone alcohol 6.53
    N,N-dimethylaniline 1.47
    acrylonitrile 11.21
    aniline 7.18
    1,3-propanediol 113.54
    bromobenzene 1.47
    dibromomethane 5.38
    1,1,2,2-tetrachloroethane 12.62
    2-methyl-cyclohexyl acetate 3.42
    tetrabutyl urea 4.13
    diisobutyl methanol 1.1
    2-phenylethanol 6.16
    styrene 0.52
    dioctyl adipate 2.01
    dimethyl sulfate 27.91
    ethyl butyrate 4.35
    methyl lactate 31.77
    butyl lactate 10.42
    diethyl carbonate 3.54
    propanediol butyl ether 19.49
    triethyl orthoformate 5.09
    p-tert-butyltoluene 1.03
    methyl 4-tert-butylbenzoate 5.67
    morpholine 23.86
    tert-butylamine 1.9
    n-dodecanol 0.97
    dimethoxymethane 12.52
    ethylene carbonate 23.41
    cyrene 27.89
    2-ethoxyethyl acetate 4.38
    2-ethylhexyl acetate 2.5
    1,2,4-trichlorobenzene 4.62
    4-methylpyridine 5.36
    dibutyl ether 0.96
    2,6-dimethyl-4-heptanol 1.1
    DEF 14.27
    dimethyl isosorbide 18.51
    tetrachloroethylene 17.38
    eugenol 10.26
    triacetin 5.99
    span 80 12.58
    1,4-butanediol 38.4
    1,1-dichloroethane 2.0
    2-methyl-1-pentanol 3.01
    methyl formate 61.9
    2-methyl-1-butanol 6.89
    n-decane 0.24
    butyronitrile 3.72
    3,7-dimethyl-1-octanol 1.37
    1-chlorooctane 0.64
    1-chlorotetradecane 0.28
    n-nonane 0.24
    undecane 0.17
    tert-butylcyclohexane 0.2
    cyclooctane 0.39
    cyclopentanol 24.64
    tetrahydropyran 5.4
    tert-amyl methyl ether 1.17
    2,5,8-trioxanonane 15.95
    1-hexene 0.57
    2-isopropoxyethanol 10.96
    2,2,2-trifluoroethanol 192.99
    methyl butyrate 5.27

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction