Tetradifon

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  • Identifiers

    CAS number
    116-29-0

    Molecular formula
    C12H6Cl4O2S

    SMILES
    C1=CC(=CC=C1S(=O)(=O)C2=CC(=C(C=C2Cl)Cl)Cl)Cl

    Safety labels

    Irritant
    Irritant

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 57.83%
    Bitter 23.79%
    Cooked 23.28%
    Burnt 22.88%
    Meaty 22.11%
    Savory 21.52%
    Grape 19.25%
    Roasted 19.0%
    Fruity 17.98%
    Phenolic 17.34%

     

    Flavor
    Bitter 83.48%
    Odorless 32.22%
    Nitrile 20.4%
    Very strong 18.93%
    Bland 18.5%
    Indole 18.39%
    Mild 18.33%
    Bread crust 18.2%
    Taco 18.1%
    Roasted peanuts 17.97%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.1

    pKa est.
    7.44 (neutral)

    Molecular weight
    356.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    450°C

    Melting point expt.

    • 146.5 - 147.5 °C
    • MELTING POINT: 144 °C /Technical product/
    • 148-149 °C

    Flash point

    • 219.43 ˚C est.

    Solubility expt.

    • Solubility in acetone 67.3, methanol 3.46, ethyl acetate 67.3, hexane 1.52, dichloromethane 297, xylene 105 (all in g/L, 20 °C)
    • Soluble in aromatic hydrocarbon solvents, dioxan
    • AT 18 °C: 0.4 G/100 G PETROLEUM ETHER; 7.1 G/100 G ETHYL ACETATE; 10.5 G/100 G METHYL ETHYL KETONE; AND 1.6 G/100 G CARBON TETRACHLORIDE.
    • In water, 7.80X10-2 mg/L @ 20 °C
    • Sol in water ... at 20 °C, 0.08 mg/l.
    • Solubility in water at 20 °C: none

  • Synonyms

    • TETRADIFON
    • 116-29-0
    • Tetradichlone
    • Duphar
    • Polacaritox
    • Akaritox
    • Aredion
    • Roztoczol
    • Roztozol
    • Mition
    • Tedion
    • Roztoczol extra
    • 2,4,5,4'-Tetrachlorodiphenyl sulfone
    • Childion
    • Tetradiphon
    • Tetrafidon
    • Dorvert
    • Tedane
    • Tedane Combi
    • Aracnol K
    • Turbair Acaricide
    • 1,2,4-Trichloro-5-((4-chlorophenyl)sulfonyl)benzene
    • 2,4,4',5-Tetrachlorodiphenyl sulfone
    • Tedion V-18
    • 4-Chlorophenyl 2,4,5-trichlorophenyl sulfone
    • Benzene, 1,2,4-trichloro-5-[(4-chlorophenyl)sulfonyl]-
    • Tetradifon [ISO]
    • FMC 5488
    • NIA 5488
    • p-Chlorophenyl 2,4,5-trichlorophenyl sulfone
    • 1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene
    • TIP8EA8VTS
    • Systematic Names
    • 1,2,4-trichloro-5-(4-chlorophenyl)sulfonylbenzene
    • 2,4,5,4'-Tetrachlorodiphenylsulphone
    • Benzene, 1,2,4-trichloro-5-((4-chlorophenyl)sulfonyl)-
    • ENT 23,737
    • Sulfone, 2,4,4',5-tetrachlorodiphenyl
    • DTXSID7021316
    • V-18
    • CHEBI:39330
    • TETRADIFON [MI]
    • p-Chlorophenyl 2,4,5-trichlorophenyl sulphone
    • Sulfone, p-chlorophenyl 2,4,5-trichlorophenyl
    • TETRADIFON [HSDB]
    • 3,4,6,4'-Tetrachlor-diphenylsulfon
    • 2,4,4',5-Tetrachloor-difenyl-sulfon
    • 2,4,4',5-Tetrachlor-diphenyl-sulfon
    • 2,4,4',5-Tetracloro-difenil-solfone
    • DTXCID401316
    • Caswell No. 836
    • TCDS cpd
    • CAS-116-29-0
    • Tetradifon [ANSI:BSI:ISO]
    • CCRIS 4026
    • HSDB 1773
    • UNII-TIP8EA8VTS
    • EINECS 204-134-2
    • EPA Pesticide Chemical Code 079202
    • 2,4,4',5-Tetrachlorodiphenyl sulphone
    • BRN 2292528
    • Acarvin
    • Mitifon
    • AI3-23737
    • Acaroil TD
    • 2,4,4',5-Tetrachloor-difenyl-sulfon [Dutch]
    • 3,4,6,4'-Tetrachlor-diphenylsulfon [German]
    • 4-Chlorophenyl 2,4,5-trichlorophenyl sulphone
    • 2,4,4',5-Tetrachlor-diphenyl-sulfon [German]
    • 2,4,4',5-Tetracloro-difenil-solfone [Italian]
    • 1,2,4-trichloro-5-((4-chlorophenyl)sulfonyl)benzene;4-chlorophenyl 2,4,5-trichlorophenyl sulfone
    • 1,2,4-trichloro-5-[(4-chlorophenyl)sulfonyl]benzene;4-chlorophenyl 2,4,5-trichlorophenyl sulfone
    • 2,4,4',5-Tetrachlorodiphenyl sulphone (british)
    • Tedion V18
    • Tetradifon 10 microg/mL in Cyclohexane
    • Tetradifon 100 microg/mL in Cyclohexane
    • Agrex T-7.5
    • SCHEMBL27902
    • CHEMBL437926
    • MLGCXEBRWGEOQX-UHFFFAOYSA-
    • 2,4,4',5Tetrachloordifenylsulfon
    • 2,4,4',5Tetrachlordiphenylsulfon
    • 2,4,4',5Tetraclorodifenilsolfone
    • 3,4,6,4'Tetrachlordiphenylsulfon
    • Tox21_202396
    • Tox21_302766
    • 2,4,5,4'Tetrachlorodiphenylsulphone
    • 2,4,4',5Tetrachlorodiphenyl sulfone
    • 2,4,5,4'Tetrachlorodiphenyl sulfone
    • AKOS015960875
    • Sulfone, 2,4,4',5tetrachlorodiphenyl
    • NCGC00163708-01
    • NCGC00163708-02
    • NCGC00163708-03
    • NCGC00256511-01
    • NCGC00259945-01
    • AC-12472
    • pChlorophenyl2,4,5trichlorophenyl sulfone
    • pChlorophenyl 2,4,5trichlorophenyl sulfone
    • 4Chlorophenyl 2,4,5trichlorophenyl sulfone
    • DB-041307
    • HY-119725
    • pChlorophenyl 2,4,5trichlorophenyl sulphone
    • 4Chlorophenyl 2,4,5trichlorophenyl sulphone
    • CS-0077874
    • NS00002806
    • Tetradifon, PESTANAL(R), analytical standard
    • C18451
    • p-Chlorophenyl, 2,4,5-trichlorophenyl sulfone
    • 1,2,4Trichloro5((4chlorophenyl)sulfonyl)benzene
    • 2,4,4',5Tetrachlorodiphenyl sulphone (British)
    • Q413684
    • Benzene, 1,2,4trichloro5((4chlorophenyl)sulfonyl)
    • Sulfone, pchlorophenyl 2,4,5trichlorophenyl (7CI)
    • 4-CHLOROPHENYL, 2,4,5-TRICHLOROPHENYL SULFONE
    • 1,2,4-Trichloro-5-((4-chlorophenyl)sulfonyl)-benzene
    • Benzene, 1,2,4-trichloro-5-(4-chlorophenyl)sulfonyl-
    • Sulfone, pchlorophenyl 2,4,5trichlorophenyl (7CI)(8CI)
    • 1,2,4-TRICHLORO-5-((4-CHLOROPHENYL)-SULFONYL)BENZENE
    • 204-134-2
    • InChI=1/C12H6Cl4O2S/c13-7-1-3-8(4-2-7)19(17,18)12-6-10(15)9(14)5-11(12)16/h1-6H

  • Applications

    Tetradifon is primarily used in agriculture as an acaricide/insecticide to control mites and certain pests on fruit trees and vegetables, typically formulated as emulsifiable concentrates or wettable powders; it may also be considered for household pest-control products in some formulations; in chemical production it can serve as an intermediate or processing aid in the synthesis of other specialty compounds; its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1.83
    methanol 0.89
    isopropanol 1.64
    water 0.0
    ethyl acetate 33.72
    n-propanol 3.34
    acetone 26.33
    n-butanol 3.07
    acetonitrile 10.26
    DMF 73.42
    toluene 35.78
    isobutanol 2.37
    1,4-dioxane 46.87
    methyl acetate 41.03
    THF 103.16
    2-butanone 63.25
    n-pentanol 4.87
    sec-butanol 7.14
    n-hexane 0.51
    ethylene glycol 0.58
    NMP 100.1
    cyclohexane 1.02
    DMSO 7.17
    n-butyl acetate 49.04
    n-octanol 7.25
    chloroform 58.42
    n-propyl acetate 40.83
    acetic acid 7.27
    dichloromethane 41.96
    cyclohexanone 82.19
    propylene glycol 1.46
    isopropyl acetate 31.95
    DMAc 141.21
    2-ethoxyethanol 16.98
    isopentanol 3.56
    n-heptane 1.93
    ethyl formate 13.82
    1,2-dichloroethane 17.8
    n-hexanol 8.01
    2-methoxyethanol 15.51
    isobutyl acetate 21.98
    tetrachloromethane 2.49
    n-pentyl acetate 34.83
    transcutol 88.71
    n-heptanol 6.74
    ethylbenzene 23.56
    MIBK 24.72
    2-propoxyethanol 29.23
    tert-butanol 2.86
    MTBE 18.23
    2-butoxyethanol 19.78
    propionic acid 7.09
    o-xylene 22.65
    formic acid 2.11
    diethyl ether 13.1
    m-xylene 19.6
    p-xylene 24.9
    chlorobenzene 25.31
    dimethyl carbonate 23.61
    n-octane 0.98
    formamide 9.53
    cyclopentanone 108.23
    2-pentanone 35.55
    anisole 68.2
    cyclopentyl methyl ether 45.78
    gamma-butyrolactone 91.53
    1-methoxy-2-propanol 16.37
    pyridine 89.82
    3-pentanone 40.55
    furfural 101.49
    n-dodecane 0.97
    diethylene glycol 12.28
    diisopropyl ether 7.26
    tert-amyl alcohol 9.27
    acetylacetone 71.44
    n-hexadecane 1.21
    acetophenone 77.17
    methyl propionate 35.62
    isopentyl acetate 42.82
    trichloroethylene 115.11
    n-nonanol 8.71
    cyclohexanol 9.8
    benzyl alcohol 26.07
    2-ethylhexanol 11.41
    isooctanol 6.66
    dipropyl ether 23.75
    1,2-dichlorobenzene 26.85
    ethyl lactate 17.89
    propylene carbonate 49.28
    n-methylformamide 16.73
    2-pentanol 4.63
    n-pentane 0.41
    1-propoxy-2-propanol 28.95
    1-methoxy-2-propyl acetate 76.04
    2-(2-methoxypropoxy) propanol 43.37
    mesitylene 10.49
    ε-caprolactone 85.55
    p-cymene 17.53
    epichlorohydrin 88.22
    1,1,1-trichloroethane 24.98
    2-aminoethanol 1.69
    morpholine-4-carbaldehyde 120.93
    sulfolane 55.78
    2,2,4-trimethylpentane 0.97
    2-methyltetrahydrofuran 68.37
    n-hexyl acetate 35.11
    isooctane 0.5
    2-(2-butoxyethoxy)ethanol 38.58
    sec-butyl acetate 39.89
    tert-butyl acetate 47.75
    decalin 1.57
    glycerin 3.4
    diglyme 84.93
    acrylic acid 8.45
    isopropyl myristate 20.43
    n-butyric acid 9.4
    acetyl acetate 32.61
    di(2-ethylhexyl) phthalate 17.58
    ethyl propionate 39.18
    nitromethane 41.8
    1,2-diethoxyethane 50.46
    benzonitrile 40.2
    trioctyl phosphate 9.81
    1-bromopropane 11.91
    gamma-valerolactone 153.77
    n-decanol 6.84
    triethyl phosphate 22.79
    4-methyl-2-pentanol 4.17
    propionitrile 11.11
    vinylene carbonate 47.46
    1,1,2-trichlorotrifluoroethane 60.21
    DMS 51.65
    cumene 11.31
    2-octanol 7.85
    2-hexanone 47.65
    octyl acetate 20.96
    limonene 24.92
    1,2-dimethoxyethane 60.18
    ethyl orthosilicate 20.43
    tributyl phosphate 14.35
    diacetone alcohol 33.13
    N,N-dimethylaniline 42.59
    acrylonitrile 22.09
    aniline 23.84
    1,3-propanediol 2.77
    bromobenzene 31.18
    dibromomethane 19.27
    1,1,2,2-tetrachloroethane 63.05
    2-methyl-cyclohexyl acetate 47.63
    tetrabutyl urea 28.71
    diisobutyl methanol 8.45
    2-phenylethanol 32.8
    styrene 26.83
    dioctyl adipate 31.74
    dimethyl sulfate 34.38
    ethyl butyrate 49.53
    methyl lactate 18.45
    butyl lactate 27.16
    diethyl carbonate 29.29
    propanediol butyl ether 17.07
    triethyl orthoformate 36.8
    p-tert-butyltoluene 16.79
    methyl 4-tert-butylbenzoate 44.13
    morpholine 52.67
    tert-butylamine 1.92
    n-dodecanol 5.34
    dimethoxymethane 37.0
    ethylene carbonate 28.37
    cyrene 57.99
    2-ethoxyethyl acetate 61.3
    2-ethylhexyl acetate 42.62
    1,2,4-trichlorobenzene 43.33
    4-methylpyridine 84.29
    dibutyl ether 19.03
    2,6-dimethyl-4-heptanol 8.45
    DEF 62.56
    dimethyl isosorbide 113.93
    tetrachloroethylene 32.56
    eugenol 48.09
    triacetin 56.52
    span 80 30.28
    1,4-butanediol 1.79
    1,1-dichloroethane 18.11
    2-methyl-1-pentanol 7.59
    methyl formate 17.26
    2-methyl-1-butanol 4.96
    n-decane 1.67
    butyronitrile 9.71
    3,7-dimethyl-1-octanol 10.11
    1-chlorooctane 7.13
    1-chlorotetradecane 3.37
    n-nonane 1.34
    undecane 1.26
    tert-butylcyclohexane 1.36
    cyclooctane 0.75
    cyclopentanol 11.06
    tetrahydropyran 40.49
    tert-amyl methyl ether 30.46
    2,5,8-trioxanonane 63.61
    1-hexene 4.32
    2-isopropoxyethanol 16.53
    2,2,2-trifluoroethanol 4.91
    methyl butyrate 48.65

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction