Teprenone

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  • Identifiers

    CAS number
    6809-52-5

    Molecular formula
    C23H38O

    SMILES
    CC(=CCC/C(=C/CC/C(=C/CC/C(=C/CCC(=O)C)/C)/C)/C)C

    Safety labels

  • Odor profile

    Fragrance
    Floral 86.13%
    Fruity 56.74%
    Waxy 55.91%
    Sweet 55.02%
    Balsamic 51.59%
    Woody 51.04%
    Green 48.84%
    Rose 48.24%
    Oily 41.57%
    Fresh 37.78%

     

    Flavor
    Floral 73.66%
    Fruity 51.04%
    Waxy 43.89%
    Citrus 41.9%
    Rose 39.81%
    Fresh 38.29%
    Green 35.01%
    Sweet 33.49%
    Orange 32.32%
    Balsam 30.84%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.4

    pKa est.
    8.15 (weak base)

    Molecular weight
    330.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    382°C

    Flash point

    • 166.12 ˚C est.

  • Synonyms

    • teprenone
    • Geranylgeranylacetone
    • Selbex
    • 6809-52-5
    • Teprenona
    • Teprenonum
    • DTXCID9028546
    • DTXSID6048620
    • CHEBI:31649
    • E-0671
    • S8S8451A4O
    • 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one
    • tetraprenyl acetone
    • teprenon
    • 5,9,13,17-NONADECATETRAEN-2-ONE, 6,10,14,18-TETRAMETHYL-
    • geranyl-geranyl-acetone
    • RefChem:891362
    • geranylgeranylacetone, (E,E,E)-
    • (5E,9E,13E)-6,10,14,18-Tetramethylnonadeca-5,9,13,17-tetraen-2-one (5Z,9E,13E)-6,10,14,18-Tetramethylnonadeca-5,9,13,17-tetraen-2-one
    • Tetraprenylacetone
    • 3796-63-2
    • (5E,9E,13E)-Teprenone
    • (5E,9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
    • Teprenonum [INN-Latin]
    • Teprenona [INN-Spanish]
    • UNII-S8S8451A4O
    • 6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
    • (5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
    • 57B67OXM8F
    • C23H38O
    • MFCD00869547
    • 5,9,13,17-Nonadecatetraen-2-one, 6,10,14,18-tetramethyl-, (E,E,E)-
    • Geranylgeranyl acetone
    • All trans-Teprenone
    • Teprenone [INN:JAN]
    • UNII-57B67OXM8F
    • Selbelle
    • (5Z,9Z,13E)-Geranylgeranylacetone
    • (5Z,9Z,13Z)-Geranylgeranylacetone
    • Teprenone RS
    • NCGC00182034-01
    • Teprenone (Standard)
    • Teprenone Impurity 16
    • SCHEMBL157509
    • HY-B0779R
    • DTXSID901166719
    • HMS5084I09
    • Ea-0671
    • HY-B0779
    • Tox21_112960
    • MSK157688
    • s5006
    • AKOS015894922
    • (E,E,E)-GERANYLGERANYL ACETONE
    • CCG-267813
    • CS-3560
    • DA-48695
    • SY052774
    • CAS-6809-52-5
    • E-671
    • A12751
    • SBI-0654108.0001
    • 809T525
    • SR-01000944917
    • Q7701388
    • SR-01000944917-1
    • BRD-K11510141-001-01-8
    • BRD-K11510141-001-02-6
    • BRD-K11510141-001-03-4
    • (5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
    • 5,9,13,17-NONADECATETRAEN-2-ONE, 6,10,14,18-TETRAMETHYL-, (5E,9E,13E)-
    • (E,E,E)-Geranylgeranyl Acetone; Tetraprenylacetone; (E,E,E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
    • 6809-52-5

  • Applications

    Teprenone (CAS 6809-52-5) is primarily encountered in the pharmaceutical field as a mucosal-protective active ingredient, commonly formulated for oral gastroprotective medicines to support gastric mucosa; it is also used as a specialty intermediate or building block in chemical syntheses related to drug development and formulation research; in formulation development and testing contexts, teprenone may be evaluated for stability and compatibility as part of research programs; its application outside pharmaceuticals is limited and subject to local regulations and supplier specifications.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 12.17
    methanol 7.3
    isopropanol 8.77
    water 0.01
    ethyl acetate 70.01
    n-propanol 14.75
    acetone 19.32
    n-butanol 20.41
    acetonitrile 7.69
    DMF 17.22
    toluene 58.67
    isobutanol 11.41
    1,4-dioxane 112.68
    methyl acetate 28.82
    THF 232.88
    2-butanone 47.16
    n-pentanol 27.78
    sec-butanol 21.09
    n-hexane 38.16
    ethylene glycol 0.27
    NMP 62.74
    cyclohexane 42.5
    DMSO 20.42
    n-butyl acetate 103.76
    n-octanol 22.88
    chloroform 216.36
    n-propyl acetate 81.36
    acetic acid 9.52
    dichloromethane 161.26
    cyclohexanone 105.82
    propylene glycol 1.55
    isopropyl acetate 71.69
    DMAc 81.16
    2-ethoxyethanol 39.56
    isopentanol 24.94
    n-heptane 29.78
    ethyl formate 15.51
    1,2-dichloroethane 83.67
    n-hexanol 34.03
    2-methoxyethanol 23.51
    isobutyl acetate 73.55
    tetrachloromethane 33.26
    n-pentyl acetate 90.71
    transcutol 345.52
    n-heptanol 23.46
    ethylbenzene 71.54
    MIBK 58.52
    2-propoxyethanol 60.9
    tert-butanol 21.22
    MTBE 101.66
    2-butoxyethanol 53.75
    propionic acid 9.97
    o-xylene 49.84
    formic acid 1.44
    diethyl ether 95.56
    m-xylene 49.06
    p-xylene 73.37
    chlorobenzene 59.68
    dimethyl carbonate 8.23
    n-octane 9.39
    formamide 2.53
    cyclopentanone 79.83
    2-pentanone 53.58
    anisole 116.41
    cyclopentyl methyl ether 129.53
    gamma-butyrolactone 64.95
    1-methoxy-2-propanol 30.4
    pyridine 69.5
    3-pentanone 55.08
    furfural 55.98
    n-dodecane 4.8
    diethylene glycol 12.69
    diisopropyl ether 49.36
    tert-amyl alcohol 40.67
    acetylacetone 57.56
    n-hexadecane 5.75
    acetophenone 95.99
    methyl propionate 35.07
    isopentyl acetate 125.41
    trichloroethylene 148.9
    n-nonanol 30.4
    cyclohexanol 32.63
    benzyl alcohol 33.71
    2-ethylhexanol 49.71
    isooctanol 27.55
    dipropyl ether 149.77
    1,2-dichlorobenzene 78.0
    ethyl lactate 21.38
    propylene carbonate 45.83
    n-methylformamide 4.95
    2-pentanol 20.28
    n-pentane 14.46
    1-propoxy-2-propanol 71.99
    1-methoxy-2-propyl acetate 126.37
    2-(2-methoxypropoxy) propanol 108.97
    mesitylene 39.42
    ε-caprolactone 122.23
    p-cymene 49.09
    epichlorohydrin 120.21
    1,1,1-trichloroethane 106.18
    2-aminoethanol 2.15
    morpholine-4-carbaldehyde 81.57
    sulfolane 80.98
    2,2,4-trimethylpentane 17.92
    2-methyltetrahydrofuran 184.92
    n-hexyl acetate 108.55
    isooctane 10.51
    2-(2-butoxyethoxy)ethanol 112.2
    sec-butyl acetate 102.7
    tert-butyl acetate 118.41
    decalin 38.17
    glycerin 2.73
    diglyme 249.42
    acrylic acid 5.11
    isopropyl myristate 57.05
    n-butyric acid 32.11
    acetyl acetate 39.76
    di(2-ethylhexyl) phthalate 42.09
    ethyl propionate 84.94
    nitromethane 16.75
    1,2-diethoxyethane 218.03
    benzonitrile 30.8
    trioctyl phosphate 22.23
    1-bromopropane 92.06
    gamma-valerolactone 123.58
    n-decanol 20.06
    triethyl phosphate 70.79
    4-methyl-2-pentanol 20.25
    propionitrile 13.79
    vinylene carbonate 31.52
    1,1,2-trichlorotrifluoroethane 51.88
    DMS 44.58
    cumene 54.56
    2-octanol 20.47
    2-hexanone 94.27
    octyl acetate 57.86
    limonene 77.63
    1,2-dimethoxyethane 137.72
    ethyl orthosilicate 89.9
    tributyl phosphate 32.39
    diacetone alcohol 61.37
    N,N-dimethylaniline 101.01
    acrylonitrile 9.42
    aniline 28.64
    1,3-propanediol 6.14
    bromobenzene 80.0
    dibromomethane 118.44
    1,1,2,2-tetrachloroethane 161.64
    2-methyl-cyclohexyl acetate 153.97
    tetrabutyl urea 49.86
    diisobutyl methanol 40.62
    2-phenylethanol 48.17
    styrene 64.16
    dioctyl adipate 88.71
    dimethyl sulfate 14.45
    ethyl butyrate 145.47
    methyl lactate 8.97
    butyl lactate 46.15
    diethyl carbonate 70.72
    propanediol butyl ether 30.22
    triethyl orthoformate 146.98
    p-tert-butyltoluene 46.62
    methyl 4-tert-butylbenzoate 102.22
    morpholine 120.97
    tert-butylamine 21.69
    n-dodecanol 14.4
    dimethoxymethane 34.96
    ethylene carbonate 28.94
    cyrene 73.52
    2-ethoxyethyl acetate 112.04
    2-ethylhexyl acetate 123.2
    1,2,4-trichlorobenzene 91.0
    4-methylpyridine 83.6
    dibutyl ether 120.99
    2,6-dimethyl-4-heptanol 40.62
    DEF 73.7
    dimethyl isosorbide 242.31
    tetrachloroethylene 83.47
    eugenol 71.17
    triacetin 106.23
    span 80 82.48
    1,4-butanediol 2.99
    1,1-dichloroethane 72.8
    2-methyl-1-pentanol 43.64
    methyl formate 3.86
    2-methyl-1-butanol 25.2
    n-decane 11.44
    butyronitrile 23.08
    3,7-dimethyl-1-octanol 39.32
    1-chlorooctane 41.73
    1-chlorotetradecane 13.93
    n-nonane 10.42
    undecane 6.91
    tert-butylcyclohexane 35.55
    cyclooctane 19.84
    cyclopentanol 19.53
    tetrahydropyran 171.87
    tert-amyl methyl ether 119.57
    2,5,8-trioxanonane 174.84
    1-hexene 73.25
    2-isopropoxyethanol 44.56
    2,2,2-trifluoroethanol 3.1
    methyl butyrate 96.1

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction